a knowledge base of biological literature

... series of metabolic pathway databases based on the EcoCyc infrastructure, including HumanCyc, a database of human pathways [33,34] Although HumanCyc includes a modest number of curated reactions, ... literature- based curation of genetic and physical interactions These databases are broad but shallow; individual interactions have little additional information, and hence are not easily associated ... large 'reaction map' that summarizes all of the currently curated or inferred pathways, and a table of contents that describes each of the top-level pathways in the database In the reaction map,...

Ngày tải lên: 14/08/2014, 20:22

Ngày tải lên: 14/08/2014, 21:20

... coordination, in data acquisition and analysis, and in manuscript preparation EG and AZ participated in data acquisition and in manuscript preparation All authors read and approved the final manuscript ... 'clinical trials phase II', 'clinical trials phase III', and 'clinical trials phase IV' We searched even in the abstract databases of both the European League Against Rheumatism (EULAR) and the ACR ... biomarkers are not at hand Furthermore, prescribing a biological agent is an important decision that can greatly impact the quality of life of a patient and can be associated with varying medical costs,...

Ngày tải lên: 09/08/2014, 14:22

... Psychiatric Research, USA; Faiza Anwar, Women’s Health Educator, Australia; Victor Aparicio Basauri, WHO Collaborating Centre, Spain; Lara Asuncion Ramon de la Fuente, National Institute of Psychiatry, ... Ahmed G Abou El-Azayem, Eastern Mediterranean Regional Council of the World Federation for Mental Health, Egypt; Mlay Akwillina, Reproductive Health Project, Tanzania; Mary Jane Alexander, Nathan ... University, USA; Amnon Carmi, International Center for Health Law and Ethics, Haifa University, Israel; Rebecca J Cook, University of Toronto, Canada; Dilbera, DAJA Organization, Macedonia; Mary Ellsberg,...

Ngày tải lên: 06/03/2014, 02:20

... measures No clinical audit of HR performance to assess EMOC quality was found in the literature Performance measures are often combined with an analysis of the availability of material and organizational ... Green A, Pearson S: The implications of shortages of health professionals for maternal health in sub-saharan Africa Reproductive Health Matters 2006, 14:40-50 Islam MT, Haque YA, Waxman R, Bhuiyan ... Par tially addr essed theme in study [56] User s’ assessment Addr essed aspects Hospital-based morbidity and mortality Acceptability, patients’ satisfaction Caesarean rates, case fatality rates...

Ngày tải lên: 18/06/2014, 17:20

... Australia [14] and Canada [7] Generally male pharmacists predominated above the age of 50 Education One response to the shortage of pharmacists was found to be a planned expansion of the number of ... numbers of entrants to the profession However, this expansion presented many concerns regarding quality of teaching, the number of available pharmacy-trained faculty and the academic standard of applicants ... Relevant peer-reviewed and non-peer-reviewed international literature was initially identified via searches on electronic databases The databases searched included MEDLINE, EMBASE, International...

Ngày tải lên: 18/06/2014, 17:20

... of ET and MSrelated tremor in 12 patients of advanced age (median of 75 years) Patient outcomes were also assessed using the tremor scale diagrammed by Fahn-Tolosa Of the 11 evaluable patients, ... survival of neurons adjacent to the thalamic lesion after GK thalamotomy by Ohye et al [16] They performed a total of 36 thalamotomies in 31 patients and analyzed the treatment outcomes It was noted ... LD: Gamma knife thalamotomy for multiple sclerosis tremor Surg Neurol 2007, 68:394-399 Niranjan A, Jawahar A, Kondziolka D, Lunsford LD: A comparison of surgical approaches for the management of...

Ngày tải lên: 09/08/2014, 03:21

... Although majority of the nodes are located in internal iliac and external iliac areas, nodes have been found in also presacral, parametrial and pararectal areas [33] In a sentinel node study carried ... blue, have caused disappointment at first [1] DeCesare et al., demonstrated the applicability of intra-operative gamma ray use, and a year later, Hullu et al., demonstrated the applicability of a ... Of the cases, 90% are squamous cell carcinomas, while the rest are melanoma, adenocarcinoma, basal cell carcinoma and sarcoma [7] Nodal metastasis in vulva cancer is the main prognostic factor,...

Ngày tải lên: 09/08/2014, 07:21

... echocardiography papillary fibroelastoma usually arise via a pedicle from mitral valve tissue or adjacent endocardium, and have a characteristic frond-like appearance [31] A remarkable feature that LS ... GR: Association of antibodies against phospholipids with heart valve disease in systemic lupus erythematosus Lancet 1990, 335:1541-4 Takayama T, Teramura M, Sakai H, Tamaki S, Okabayashi T, Kawashima ... [47] Again stressing the importance of anticoagulation in this disease In addition, (SLE associated) renal failure can accelerate bioprosthetic degeneration as a consequence of abnormal calcium and...

Ngày tải lên: 10/08/2014, 10:20

... publication and interview data will be analyzed A research assistant will enter findings into a data matrix to facilitate comparison of how each publication performs on principal components of each ... The main decision-makers and stakeholders of this knowledge synthesis are patients, public, government, and health professional organizations in Canada and abroad that are interested in, or affected ... Canadian Diabetes Association Clinical Practice Guidelines Expert Committee: Canadian Diabetes Association 2003 Clinical Practice Guidelines for the Prevention and Management of Diabetes in Canada...

Ngày tải lên: 11/08/2014, 05:21

... publication and interview data will be analyzed A research assistant will enter findings into a data matrix to facilitate comparison of how each publication performs on principal components of each ... The main decision-makers and stakeholders of this knowledge synthesis are patients, public, government, and health professional organizations in Canada and abroad that are interested in, or affected ... Canadian Diabetes Association Clinical Practice Guidelines Expert Committee: Canadian Diabetes Association 2003 Clinical Practice Guidelines for the Prevention and Management of Diabetes in Canada...

Ngày tải lên: 11/08/2014, 16:20

... patients were on antidepressant medication, and all had seen their clinicians on at least two occasions for standard treatment and standard psycho-education as a part of standard clinical care prior ... clear language at the appropriate level (Grade 9) and was as much as possible without medical or psychiatric jargon, 3) each requires patient knowledge to be demonstrated in a specific area of ... women than men Q5 Relapse risks of, and triggering factors Knowledge of the chances of relapse rates after remission Understanding that sopping antidepressants after recovery may lead to relapse...

Ngày tải lên: 11/08/2014, 17:20

... they are generally downplayed and not affect the decisiveness of the conclusions Interpretation of the findings is often biased and obvious caveats and alternative explanations for the data are often ... unbearable automaticity of being American Psychologist 1999, 54:462-479 42 American Psychiatric Association: Diagnostic and statistical manual of mental disorders: DSM-IV-TR Washington, DC: American ... items None of the articles we reviewed acknowledged the difficulty inherent in taking participants’ causal attributions at face value Some even assume that participants can accurately attribute...

Ngày tải lên: 11/08/2014, 18:20

... properties is available in the supplementary material (additional File 1, additional File & Additional File 3.) absolute magnitude of correlations, a valid measure of PF was expected to correlate strongly ... PM, Taal E, van de Laar MA: Rasch analysis of the Dutch Health Assessment Questionnaire disability index and the Health Assessment Questionnaire II in patients with rheumatoid arthritis Arthritis ... factor analysis was applied before calculating Cronbach’s a The AIMS was the only questionnaire to receive a negative rating, because a < 0.70 was reported for the physical activities and activities...

Ngày tải lên: 12/08/2014, 00:20

... hypoglycaemic episodes We provide recommendations for a feasible and reliable insulin/ glucose algorithm Materials and methods We performed a search of the PubMed, Embase and Cochrane databases ... or antiarrhythmic therapy after cardiopulmonary bypass J Cardiothorac Vasc Anesth 2002, 16:405-412 Jaspers CA, Elte JW, Olthof G: Perioperative diabetes regulation with the help of a standard ... satisfied the inclusion criteria The abstracts and the abstracts of 'related papers' were evaluated by two researchers (SM and JJML); all papers that satisfied the inclusion criteria were read...

Ngày tải lên: 12/08/2014, 23:21

... intra-assay CV of less than or equal to 7% and an interassay CV of less than or equal to 10%, and at concentrations greater than 0.3 ng/ml the intra-assay CV is less than or equal to 3% and the interassay ... bcase report Aa disc, dissection of the aortic artery; APACHE, acute physiology and chronic health evaluation; AT III, antithrombin III; CABG, coronary artery bypass grafting; CBT, coronary artery ... rejection after heart and/or lung transplantation from bacterial and fungal infections PCT levels typically remain unchanged after acute rejection but increase markedly after bacterial and fungal infections...

Ngày tải lên: 13/08/2014, 03:20

... treatment (for example, central venous pressure of mmHg) Hemodynamic measures and goals that were listed as part of the trial entry criteria but were not included as part of a mandated treatment ... Fewer than 30% of all clinical trials in the field of sepsis have mandated hemodynamic treatment goals for patient management For those studies that report hemodynamic goals of therapy, there are ... Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: A randomized controlled trial JAMA 2003, 290:238-247 28 Abraham E, Laterre P, Garg R, Levy H, Talwar...

Ngày tải lên: 13/08/2014, 03:21

... dT4 = stavudine, DLV = delaviridine, IDV = indinavir, 3TC = lamivudine HAART HAART HAART HAART HAART, mainly HAART Antiretroviral treatment, not specified HAART Antiretroviral treatment (HAART 31%) ... and adherence in patients with HIV/AIDS, we evaluated the available data regarding the possible association between the major separate determinants of SES (income, education, occupation) and adherence ... emphasized that a statistically significant association between income and education, two main determinants of SES, and adherence was found in only half and less than a third of the studies that...

Ngày tải lên: 13/08/2014, 06:20

... taken in account Further studies are warranted to validate clinical criteria against pathological diagnosis The role of bacteriological data in improving the accuracy of a clinical diagnosis of ... Nanas S, Argyropoulou A, Margariti G, Kyprianou T, Papagalos E, Paniara O, Roussos C: The diagnostic value of gram stain of bronchoalveolar lavage samples in patients with suspected ventilator-associated ... Chassard D: An evaluation of the Gram stain in protected bronchoalveolar lavage fluid for the early diagnosis of ventilator-associated pneumonia Anesth Analg 2001, 92:442-447 47 Prekates A, Nanas...

Ngày tải lên: 13/08/2014, 10:20

... Djupsjobacka, Vertical posture and head stability in patients with chronic neck pain Journal of rehabilitation medicine : official journal of the UEMS European Board of Physical and Rehabilitation ... alterations caused by the neck pain Overall, the lack of data available, no conclusions can be drawn regarding a possible relationship between postural stability and perceived pain or disability ... doi:10.1016/j.neulet.2003.12.047 P Era, P Sainio, S Koskinen, P Haavisto, M Vaara, A Aromaa, Postural balance in a random sample of 7,979 subjects aged 30 years and over Gerontology 52, 204–213 (2006)...

Ngày tải lên: 13/08/2014, 15:21