... ASY, Celgene, Novartis, and Methylgene Authors' contributions GG, DM, and AY contributed equally to the content and focus of the manuscript from its earliest conception All authors read and approved ... infiltration of pleural fluids and an association between effusions and immunemediated reactions, such as rash and autoimmune events [24,26] It has been suggested that dasatinib may inhibit the function ... http://www.jhoonline.org/content/2/1/46 Dasatinib Dasatinib is a thiazole carboximide with potent activity against BCR-ABL and also SFKs [15] This agent has 325fold greater activity against unmutated BCR-ABL in vitro than imatinib,...
Ngày tải lên: 10/08/2014, 22:20
... dermatologists, may represent an essential issue for an optimal overall management of cases with a congenital primary lymphedema [14] Conclusions Assessing the impact of the duration and severity of the condition ... lymphedema in a 33-year old female Discussion In the first case the analysis of SF-36 results disclosed a significant functional impairment with a slight impact of the condition on emotional and social ... family history of similar disorders A conventional approach was applied, involving elevation of the affected limb, massage, physical activity and compression with elastic stockings On physical...
Ngày tải lên: 25/10/2012, 11:40
Tài liệu Sexual Coercion and Reproductive Health, A focus on Research doc
... Pan American Health Organization and the Organization of American States -recognized the gravity of gender-based abuse and passed resolutions condemning it A coalition of more than 900 international ... prostitution), sexually transmitted diseases (STDs), neonatal and maternal mortality and chronic pelvic pain In addition, there is a growing consensus among scholars, jurists and human rights activists ... documented consequences of sexual abuse are early onset of sexual activity and an inability to distinguish sexual from affectionate behavior (Donaldson, Whalen and Anastas, 1989; Browne and Finkelhor,...
Ngày tải lên: 13/02/2014, 10:20
Tài liệu Accounting Information Systems (AIS) and Knowledge Management: A Case Study pptx
... called Project Accountants) and head office such as the Financial Accountants, Management Accountants and Finance Manager are the internal users of the system Also, the management team that consists ... existing value of accountants AIS also provide information on both actual and budget data of the organisation that helps company’s management to plan and control business operation Good management of ... Director, Managing Director Tactical Chief Operating Officer, General Manager (Finance) Operational Finance Manager, Management Accountant, Financial Accountant, Project Accountant Transaction Processing...
Ngày tải lên: 17/02/2014, 09:20
Tài liệu LAND-BASED POLLUTION SOURCES: A global Synopsis of Land-Based Pollui on Sources science and transboundary management pdf
... regulation of pollution discharge and other impact-generating activities; Long-term lease agreements and management rights; Education and training; Education tools to raise awareness; and National, ... nutrients and contaminants into the marine environment / Marine Photobank 2008, G Bergsma Resilience and adaptive capacity; Participation in management and governance; and Collaborative learning and ... China) and Batangas Bay Demonstration Project (Philippines), and one site that demonstrates transboundary marine pollution, the “Malacca Straits Demonstration Project”, which assesses and manages...
Ngày tải lên: 17/02/2014, 10:20
Báo cáo khoa học: A study on genomic distribution and sequence features of human long inverted repeats reveals species-specific intronic inverted repeats pptx
... study on human long inverted repeats Y Wang and F C C Leung Table GO terms over-represented in human genes having human- specific LIRs The genes are human orthologs that have at least one human- specific ... essential for the initiation of DNA replication in plasmids, bacteria, eukaryotic viruses and mammalian cells [24] The inverted repeats in introns are able to affect the alternative splicing of exons ... them have been implicated as the mediator of constitutional t(11;22) translocation in humans [38] Although there are also a large number of (CA)n and (GA)n repeats in the human genome, the frequency...
Ngày tải lên: 07/03/2014, 00:20
A study on English idioms and proverbs expressing human feelings and emotions
... typical idioms and proverbs on human feelings and emotions are presented and analyzed Particularly , I pay attention to collect and analyze idioms and proverbs on human feelings and emotions , ... proverbs relating to human being feelings and emotions are large and plentiful Because of my limitation of knowledge and time, some typical feelings and emotions are mentioned in the graduation paper ... human feelings and emotions: Human beings are a higher animal than others in natural world; thus, human being‟s brain is constructed more complicatedly than others An evidence is that an human...
Ngày tải lên: 20/03/2014, 01:26
The Semantic Web: A Guide to the Future of XML, Web Services, and Knowledge Management doc
... “semantic algebra.” This allows the combination and recombination of data at a more atomic level and very fine-grained analysis of data Thus, in this stage, data no longer exists as a blob but as ... information, and save you a lot of time and work If you had a corporate knowledge base that could be searched and analyzed by software agents, you could have Web-based applications that save you a ... relation as depicted in Figure 1.7: If a person C is a male and childOf a person A, then person C is a “sonOf” person A If a person B is a male and siblingOf a person A, then person B is a “brotherOf”...
Ngày tải lên: 27/06/2014, 08:20
From The Bit Bucket: (A)Musings on Engineering, Supervision, and Management Francis W. Porretto pdf
... COM and DCOM standards, the CORBA standard, and a number of similar application interface patterns But a surprising number of vendors regard their allegiance to such meta-standards as revocable ... Christmas season, for centuries a time of relaxation, pleasure, and renewal, can be so once again Yes, some work and expense are involved, but even that, properly approached and suitably apportioned, ... Jones has painted a bull's-eye on his back: he's guaranteed that Davis, and any other manager who notices what Davis has done, will return with additional requests Why not? By accommodating Davis,...
Ngày tải lên: 27/06/2014, 23:20
Management A Focus on Leaders pdf
... Review or Evaluate Mission, Vision, Goals, and Strategies (pg 162) Steps and 3: Conduct Internal and External Analyses (pg 162) SWOT Analysis: A Popular Approach to Internal and External Analysis ... practical application that will support you both in life and at work • Integration of the foundations of management As management changes, how we view management must also change Scholars and ... experience and apply the concepts, explore the additional material associated with Chapter Social Changes Today Part Part Part Part Part 1: Leading and Managing for Today and the Future (Chapters...
Ngày tải lên: 29/06/2014, 08:20
The Semantic Web:A Guide to the Future of XML, Web Services, and Knowledge Management phần 2 potx
... information, and save you a lot of time and work If you had a corporate knowledge base that could be searched and analyzed by software agents, you could have Web-based applications that save you a ... relation as depicted in Figure 1.7: If a person C is a male and childOf a person A, then person C is a “sonOf” person A If a person B is a male and siblingOf a person A, then person B is a “brotherOf” ... Semantic Web technologies are limitless Information Sharing and Knowledge Discovery Information sharing and communication are paramount in any organization, but as most organizations grow and...
Ngày tải lên: 14/08/2014, 12:20
The Semantic Web:A Guide to the Future of XML, Web Services, and Knowledge Management phần 3 pdf
... universal syntax for exchanging data between organizations By agreeing on a standard schema, organization can produce these text documents that can be validated, transmitted, and parsed by any application ... primary reasons for XML’s success: XML creates application-independent documents and data XML can be inspected by humans and processed by any application It has a standard syntax for meta data ... application, a Java applet, or server-side Web page, can take the information received from that application and style it to provide graphics and presentation Because only XML data is sent back...
Ngày tải lên: 14/08/2014, 12:20
The Semantic Web:A Guide to the Future of XML, Web Services, and Knowledge Management phần 4 pdf
... reification Most databases treat data as facts, so it is a stretch to think about data as assertions One commonsense application of reification is annotations of other people’s work Annotations, ... available cars on a certain date, lists rental rates, and allows an application to make a reservation for a car Expense report creator This Web service automatically creates expense reports, based ... and authorization information between services and servers, and XACML is the authentication and authorization information The idea of XACML is that XML documents (or SOAP messages themselves) can...
Ngày tải lên: 14/08/2014, 12:20
The Semantic Web:A Guide to the Future of XML, Web Services, and Knowledge Management phần 5 ppsx
... JIVA DIA
Ngày tải lên: 14/08/2014, 12:20
The Semantic Web:A Guide to the Future of XML, Web Services, and Knowledge Management phần 6 ppsx
... constitute a taxonomy A taxonomy based on the part of relation would be an aggregation taxonomy (as opposed to a generalization/specialization taxonomy, the first kind of taxonomy we looked at) ... sometimes called a generalization/specialization taxonomy Understanding Taxonomies 147 animate object agent person manager organization employee Subclass of Figure 7.1 A simple taxonomy Taxonomies are ... The ANSI/NISO Monolingual Thesaurus Standard defines a thesaurus as a controlled vocabulary arranged in a known order and structured so that equivalence, homographic, hierarchical, and associative...
Ngày tải lên: 14/08/2014, 12:20
The Semantic Web:A Guide to the Future of XML, Web Services, and Knowledge Management phần 7 ppt
... Organization isa isa isa manages part_of isa manages President Class Company manages isa isa Manager Class Department Director Class Division manages isa isa manages Department part_of Class Division ... associations, and each topic in an association has a particular role that it plays in that association But RDF was explicitly developed to enable the description (and linkage) of meta data to ... Halpin (1995) and Ullman (1989) Understanding Taxonomies 167 people, databases, and applications that need to share domain information (a domain is just a specific subject area or area of knowledge, ...
Ngày tải lên: 14/08/2014, 12:20
The Semantic Web:A Guide to the Future of XML, Web Services, and Knowledge Management phần 8 pdf
... intension and the second is the extension In the database world, a schema is the intensional database, whereas the tuples of the database constitute the extensional database In the formal/natural language ... decision support, speech and natural language understanding, knowledge management, intelligent databases, and electronic commerce 206 Chapter As we saw in Chapter 7, an ontology can range from ... example, in an ontology, you could represent information describing the semantics of many domains: person, location, event, and so on, and the relationships among them (a person is at a location...
Ngày tải lên: 14/08/2014, 12:20
The Semantic Web:A Guide to the Future of XML, Web Services, and Knowledge Management phần 9 pps
... Rule-Based Orchestration Data Searches Manual Searches Search by Association Rule-Based Orchestration Automated Inferences Taxonomy/Classification Searches Pattern-Based Searches: On- Demand Mining ... statement into three parts: a management employee part, a managing an organization part, and a manages part But in Table 8.9, we will just that Table 8.8 Predicate Logic Example PROPOSITIONS AND ... to and so cannot tell if “x is a management_ employee” is true or not In this example, we have only two predicates, management employee and managing an organization; we have not yet teased apart...
Ngày tải lên: 14/08/2014, 12:20