a critical appraisal of the literature

... in the parametrial areas [35], whereas Levenback found 9% of the sentinel nodes in the paraaortic area, 11% in the common iliac, 71% in the external iliac, and 9% in the parametrial area in a ... Of the cases, 90% are squamous cell carcinomas, while the rest are melanoma, adenocarcinoma, basal cell carcinoma and sarcoma [7] Nodal metastasis in vulva cancer is the main prognostic factor, ... Although majority of the nodes are located in internal iliac and external iliac areas, nodes have been found in also presacral, parametrial and pararectal areas [33] In a sentinel node study carried...

Ngày tải lên: 09/08/2014, 07:21

... they are generally downplayed and not affect the decisiveness of the conclusions Interpretation of the findings is often biased and obvious caveats and alternative explanations for the data are ... asked them, among other aspects of their experience, about addiction and loss of autonomy The claim that participants could validly report physical addiction to nicotine was based on the observation ... that “When asked what exactly it was they were addicted to, participants readily answered that it is the nicotine in cigarettes.” Clearly, the responders had no way of knowing this for a fact and...

Ngày tải lên: 11/08/2014, 18:20

... from an efficiency perspective Critical appraisal of the economic analysis of IABP therapy in AMI patients The factors which we consider when critically appraising an economic analysis are summarized ... care Intracoronary thrombolysis was used in 42% of patients later randomized to IABP therapy compared to 46% of patients in the standard therapy arm Intravenous heparin was used for a mean of ... [10], randomization took place at the end of the initial emergency catheterization, before the patient was transferred to the critical care unit (CCU) The randomization was stratified by clinical...

Ngày tải lên: 12/08/2014, 18:20

... finding and the investigators should be congratulated for their efforts Nevertheless, because of the landmark nature of the trial, a critical analysis is certainly in order The purpose of the present ... CRRT and IHD doses is complex due to the nonsteady-state nature of the latter therapy A physiologically logical approach to comparing the two modalities is the standardized urea Kt/V parameter, as ... Tolwani and colleagues [8] A relatively high plasma creatinine, the result of both a predominantly male patient population and late renal replacement therapy initiation, may have contributed to the...

Ngày tải lên: 13/08/2014, 11:22

... first analysis (frontline treatment alone) Outcome The primary goal of the analyses was to compare the response rates of R-CVP and R-CHOP in the treatment of patients with FL as frontline therapy ... separately Czuczman et al [4] and Marcus et al [7] did not include patients of stage To make the data accurate and comparable across all four studies, we reassigned patients into two broad stages: ... early stage (Ann-Arbor stages I and II) and late stage (Ann-Arbor stages III and IV) Combining the studies, there were 439 patients, and over 98% of these were late-stage Treatment efficacy The...

Ngày tải lên: 10/08/2014, 22:20

... work of the Appraisal of Guidelines Research and Evaluation (AGREE) collaboration, an 'international collaboration of researchers and policy makers working together to improve the quality and ... purposes) Arthritis Research & Therapy Vol No Poitras et al Table Domain scores and overall assessment of the guidelines Appraisal of Guidelines Research and Evaluation domain EULAR [6] Ottawa Panel ... data, and in the revision of the manuscript All authors read and approved the final manuscript SP additionally drafted the manuscript Acknowledgements The authors are grateful to the Laboratoires...

Ngày tải lên: 09/08/2014, 10:22

... developed from the transformation are retained and transferred to other problems and parts of the healthcare organization The two exceptions to the question of sustainability are Furman and Caplan's report ... and Management in the School of Rural Public Health at the Texas A& M Health Science Center in College Station, Texas Additional material Additional file Table S1 Summaries of organizational transformation ... Backoff RW: Organizational Transformation Journal of Management Inquiry 1997, 6:235-254 Van Tonder C: 'Organisational transformation': wavering on the edge of ambiguity SA Journal of Industrial...

Ngày tải lên: 11/08/2014, 05:21

... developed from the transformation are retained and transferred to other problems and parts of the healthcare organization The two exceptions to the question of sustainability are Furman and Caplan's report ... and Management in the School of Rural Public Health at the Texas A& M Health Science Center in College Station, Texas Additional material Additional file Table S1 Summaries of organizational transformation ... Backoff RW: Organizational Transformation Journal of Management Inquiry 1997, 6:235-254 Van Tonder C: 'Organisational transformation': wavering on the edge of ambiguity SA Journal of Industrial...

Ngày tải lên: 11/08/2014, 16:20

... higher rates than usual radical rearrangements [98,312] On the other hand, the timing of radical rearrangement (radical clocks) may depend critically on the tightness of the radical cage and the ... [68], the enzyme variant still mediated N-oxygenation of the tertiary arylamine at a rate less than half that of the wild-type-catalyzed reaction [142], so that reasonable interpretation of the data ... permit the unmasking of radical intermediates that rearrange at a rate faster than that of the recombination step [16,93] Despite the apparent predominance of the hydrogen transfer mechanism as the...

Ngày tải lên: 19/02/2014, 16:20

... Psychiatric Research, USA; Faiza Anwar, Women’s Health Educator, Australia; Victor Aparicio Basauri, WHO Collaborating Centre, Spain; Lara Asuncion Ramon de la Fuente, National Institute of Psychiatry, ... Ahmed G Abou El-Azayem, Eastern Mediterranean Regional Council of the World Federation for Mental Health, Egypt; Mlay Akwillina, Reproductive Health Project, Tanzania; Mary Jane Alexander, Nathan ... non-depressed mothers of the same age, socioeconomic status and religious affiliation They found that the infants of the depressed mothers had more neonatal complications and were less adaptable and fussier...

Ngày tải lên: 06/03/2014, 02:20

... INTERNATIONAL MONETARY FUND Fiscal Affairs Department Chart of Accounts: A Critical Element of the Public Financial Management Framework Prepared by Julie Cooper and Sailendra Pattanayak Authorized ... Note: Sailendra Pattanayak is a Senior Economist in the Fiscal Affairs Department of the International Monetary Fund; Julie Cooper was a Technical Assistance Advisor in the Fiscal Affairs Department ... prepare useful financial reports and even then the accuracy of data may be questionable Account types (also called natural accounts) Revenue and expense accounts are netted off at year-end and the...

Ngày tải lên: 06/03/2014, 15:21

... in Kazakhstan are provided by the Almaty branch of Dechert Kazakhstan Limited A list of the names of the directors of Dechert Kazakhstan Limited is available for inspection at its registered office: ... the meaning of the draft of the GIC In contrast, in the scope of application of the Regulation on European venture capital funds (still in the draft phase), what are known as ‘semiprofessional’ ... requirements already given in the InvA (e.g., verification of the legality of the AIF management company’s instructions) Impact on Taxation According to the reasoning of the draft of the GIC, the revision...

Ngày tải lên: 23/03/2014, 06:20

... the greatest part of that delay was attributed to the purchase of therapeutic material by patients and their families [48] The overall evaluation of professional skills, together with the quality ... remainder of the analysis was carried out using the data extraction form and the analytical framework presented in the following section Analytical framework The concept of "quality of care" was defined ... Green A, Pearson S: The implications of shortages of health professionals for maternal health in sub-saharan Africa Reproductive Health Matters 2006, 14:40-50 Islam MT, Haque YA, Waxman R, Bhuiyan...

Ngày tải lên: 18/06/2014, 17:20

... [9], Australia [14] and Canada [7] Generally male pharmacists predominated above the age of 50 Education One response to the shortage of pharmacists was found to be a planned expansion of the ... to become an ageing profession Finally, the death of pharmacists was another factor in the permanent attrition of pharmacists from the workforce Although the death of pharmacists was not reported ... Potential areas of recruitment to the pharmacist workforce Potential areas of recruitment to the pharmacist workforce Another important issue in the recruitment of pharmacists was the lack of male...

Ngày tải lên: 18/06/2014, 17:20

... related to one another in just the same way as the genera of a family, and the groups themselves as the families of an order, or the orders of a class; while all have the same sort of structural ... of the other subkingdoms For similar reasons men and horses are arranged as members of the same Class, 'Mammalia'; men and apes as members of the same Order, 'Primates'; and if there were any animals ... you have reason to believe there has also been a great lapse of time or a great change of conditions The animals, for instance, of the newest tertiary rocks, in any part of the world, are always,...

Ngày tải lên: 28/06/2014, 19:20

... beneficial to every patient Niranjan et al [15] explored the role of GK thalamotomy in the management of ET and MSrelated tremor in 12 patients of advanced age (median of 75 years) Patient outcomes ... performed a study that evaluated the safety and efficacy of GK thalamotomy in the treatment of tremors The UPDRS and Hoehn and Yahr ratings determined by trained specialists were utilized Overall, an ... after GK thalamotomy by Ohye et al [16] They performed a total of 36 thalamotomies in 31 patients and analyzed the treatment outcomes It was noted in this analysis that in the majority of patients,...

Ngày tải lên: 09/08/2014, 03:21

... 'clinical trials phase II', 'clinical trials phase III', and 'clinical trials phase IV' We searched even in the abstract databases of both the European League Against Rheumatism (EULAR) and the ACR ... data acquisition and analysis, and in manuscript preparation EG and AZ participated in data acquisition and in manuscript preparation All authors read and approved the final manuscript 14 15 References ... tocilizumab and placebo, with a minimal impact of C-reactive protein on clinical disease activity measures The introduction of anti-TNFα marked the beginning of a new era in the treatment of RA Nonetheless,...

Ngày tải lên: 09/08/2014, 14:22

... lupus erythematosus Lancet 1990, 335:1541-4 Takayama T, Teramura M, Sakai H, Tamaki S, Okabayashi T, Kawashima T, Yamamoto T, Horie M, Suzuki T, Asai T: Perforated mitral valve aneurysm associated ... fibroelastoma On echocardiography papillary fibroelastoma usually arise via a pedicle from mitral valve tissue or adjacent endocardium, and have a characteristic frond-like appearance [31] A remarkable ... history and the echocardiographic appearance of the tumor the initial working diagnosis was papillary fibroelastoma Laboratory findings are shown in Table The patient was diagnosed with primary APS...

Ngày tải lên: 10/08/2014, 10:20

... aspects of content validity, indicating that all their items are relevant to the assessment of PF of patients with RA and all three relevant ICF chapters are measured by the items making up the ... PM, Taal E, van de Laar MA: Rasch analysis of the Dutch Health Assessment Questionnaire disability index and the Health Assessment Questionnaire II in patients with rheumatoid arthritis Arthritis ... Rosemann T, Szecsenyi J: Cultural adaptation and validation of a German version of the Arthritis Impact Measurement Scales (AIMS2) Osteoarthritis Cartilage 2007, 15(10):1128-1133 56 Bakheit A, Harries...

Ngày tải lên: 12/08/2014, 00:20

... and audit of the Bath insulin protocol Anaesth Intensive Care 2004, 32:311-316 Dazzi D, Taddei F, Gavarini A, Uggeri E, Negro R, Pezzarossa A: The control of blood glucose in the critical diabetic ... to achieve tight glycaemic control) were included if they satisfied the inclusion criteria The abstracts and the abstracts of 'related papers' were evaluated by two researchers (SM and JJML); all ... (personnel, fast and accurate point -of- care blood glucose determination, among other factors) and on the prevailing mean blood glucose level before starting a protocol Acceptance of the protocol...

Ngày tải lên: 12/08/2014, 23:21