0

aβ1 10 is more immunogenic than wsn aβ1 7

Báo cáo sinh học:

Báo cáo sinh học: "Combination of cyclosporine and erythropoietin improves brain infarct size and neurological function in rats after ischemic stroke" potx

Điện - Điện tử

... 20 07, 38:1655- 171 1 Bravata DM: Intravenous thrombolysis in acute ischaemic stroke: optimising its use in routine clinical practice CNS Drugs 2005, 19:295-302 10 Sandercock P, Berge E, Dennis ... loaded Statistical Analysis Data were expressed as mean values (mean ± SD) Statistical analysis was adequately performed by analysis of variance, followed by Scheffe multiple-comparison post hoc ... after IS) (group 2, n = 10) , IS plus CsA (20.0 mg/kg at 0.5 and 24 hour, intra-peritoneal) (group 3, n = 10) , IS plus EPO (5,000 IU/kg at 0.5, 24, and 48 hour, subcutaneous) (group 4, n = 10) ,...
  • 14
  • 475
  • 0
báo cáo hóa học:

báo cáo hóa học:" Airborne particulate matter PM2.5 from Mexico City affects the generation of reactive oxygen species by blood neutrophils from asthmatics: an in vitro approach" docx

Hóa học - Dầu khí

... × 106 ± 2.018 × 106 and 2.044 × 106 ± 1.462 × 106 , respectively, as a consequence of normal metabolism The addition of PM2.5 did not stimulate CL in NHV (3.425 × 106 ± 2.018 × 106 vs 2.889 × 106 ... Neutrophils (103 /mm3) 3.11 ± 0.55 3.84 ± 0 .74 0.0364 APO-A (mg/dL) 133.3 ± 19.93 165.0 ± 27. 59 0.0150 MPO (U/mg) 24. 17 ± 18.21 52.58 ± 25.44 0.0250 0. 07 ± 0.02 0.02 ± 0.02 0.0005 1 57. 6 ± 115.4 4 97. 6 ± ... 6) This response is reflected as higher susceptibility to lipoperoxidation in those patients (Figure 7) Discussion Oxidant generation is part of normal metabolism in many cell types and is critical...
  • 11
  • 511
  • 0
báo cáo khoa học:

báo cáo khoa học: " Differential patterns of reactive oxygen species and antioxidative mechanisms during atrazine injury and sucrose-induced tolerance in Arabidopsis thaliana plantlets" ppsx

Báo cáo khoa học

... seedlings Phytochemistry 1995, 40(3):6 57- 660 Page 17 of 18 (page number not for citation purposes) BMC Plant Biology 2009, 9:28 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 Däschner ... Arabidopsis thaliana J Exp Bot 2006, 57( 8): 171 9- 172 4 Scott I, Logan DC: Mitochondrial morphology transition is an early indicator of subsequent cell death in Arabidopsis New Phytol 2008, 177 (1):90 -101 ... At4g2 5100 At5g1 8100 At5g23 310 Localisation Superoxide dismutase (Cu-Zn) (SODCC)/copper/zinc superoxide dismutase (CSD1) Superoxide dismutase (Cu-Zn) chloroplast (SODCP)/copper/zinc superoxide dismutase...
  • 18
  • 265
  • 0
Báo cáo khoa học: Antioxidant defences and homeostasis of reactive oxygen species in different human mitochondrial DNA-depleted cell lines pot

Báo cáo khoa học: Antioxidant defences and homeostasis of reactive oxygen species in different human mitochondrial DNA-depleted cell lines pot

Báo cáo khoa học

... Homeostasis of ROS in q0 cells (Eur J Biochem 271 ) 3653 Ó FEBS 2004 ρ+ 103 104 101 102 FL1-H 103 104 101 102 103 104 103 104 101 102 FL1-H 103 104 101 102 FL1-H 103 104 60 40 Counts 20 80 100 60 ... 40 20 0 100 102 FL1-H 100 Counts 60 40 20 Counts Lung 101 80 100 100 80 100 100 60 80 100 20 0 Counts 102 FL1-H Muscle 101 30 60 90 120 150 180 100 40 Counts 60 20 Bone 40 Counts 80 100 ρ0 FL1-H ... mitochondrialsuperoxide dismutase J Biol Chem 279 , 75 12 75 20 17 Chandel, N.S & Schumacker, P.T (1999) Cells depleted of mitochondrial DNA (q0) yield insight into physiological mechanisms FEBS Lett 454, 173 – 176 18...
  • 11
  • 412
  • 0
Báo cáo y học:

Báo cáo y học: " Reduced levels of reactive oxygen species correlate with inhibition of apoptosis, rise in thioredoxin expression and increased bovine leukemia virus proviral loads" potx

Báo cáo khoa học

... intensity (X100) B 50 Control BLV *** 40 30 20 10 Non-B cells B-cells ROS levels in B cells (x 100 ) C BLV control 45 40 35 30 25 20 15 10 R2= 0.40 97, p< 0.05 10 20 DNA oxidative damage is reduced ... lymphocytosis in bovine leukemia virusinfected sheep Proc Natl Acad Sci USA 2002, 99 :100 48 -100 53 Page of 10 (page number not for citation purposes) Retrovirology 2009, 6 :102 10 11 12 13 14 15 16 17 18 ... spontaneous B cell apoptosis J Gen Virol 19 97, 78 (Pt 1):153-162 Thannickal VJ, Fanburg BL: Reactive oxygen species in cell signaling Am J Physiol Lung Cell Mol Physiol 2000, 279 :L1005-L1028 Monteiro HP,...
  • 10
  • 328
  • 0
Báo cáo y học:

Báo cáo y học: "Rheumatoid peripheral blood phagocytes are primed for activation but have impaired Fc-mediated generation of reactive oxygen specie" pptx

Báo cáo khoa học

... (× 109 /l) WBC (× 109 /l) Lymphocytes Neutrophils (× 109 /l) (× 109 /) 7. 8 1 .7 Medication M 71 58 60 12 .7 351 10. 3 Diclofenac M 53 93 36 10. 3 4 17 10. 5 8.4 1.5 Methotrexate M 78 57 74 12.4 422 7. 8 ... 1.5 - M 62 16 17 14.1 2 07 6.1 3.5 - F 61 37 - 12.3 261 6.1 3.9 1.6 Leflunomide F 75 61 77 11.6 246 6.5 5.3 0.8 - F 42 27 17 13 .7 356 12 .7 10. 4 1.8 - F 63 49 45 11.1 359 5.8 4 .7 0.6 Clarithromycin ... Invest 19 87, 79 :669- 674 Malech HL, Gallin JI: Current concepts: immunology Neutrophils in human diseases N Engl J Med 19 87, 3 17: 6 87- 694 Daeron M: Fc receptor biology Annu Rev Immunol 19 97, 15:203-234...
  • 11
  • 587
  • 0
báo cáo khoa học:

báo cáo khoa học: " Reactive oxygen species and transcript analysis upon excess light treatment in wild-type Arabidopsis thaliana vs a photosensitive mutant lacking zeaxanthin and lutein" pps

Báo cáo khoa học

... light at 10 C Functional Categories UP h ( 476 ) UP 24 h (606) DOWN h (336) DOWN 24 h ( 370 ) 19.6 ( 176 ) 17. 3 ( 210) - - 02 Energy - 2.2 (23) - - 11 Transcription - - 7. 5 ( 57) 4.5 (72 ) 01 Metabolism 14 ... BAF60b domain -1 ,10 259 976 _at AT1G76560 CP12 domain-containing -1 ,10 260465_at AT1G10 910 pentatricopeptide (PPR) repeat -1 ,10 246205_at AT4G36 970 remorin family protein -1,09 2 577 06_at AT3G12685 ... 91,6 ± 6,1 79 ,5 ± 20,4 78 ,5 ± 10, 3 Asc/(Asc +DHA) 74 ,5 ± 4,1 73 ,1 ± 1,2 78 ,6 ± 2,4 75 ,6 ± 2,2 68,9 ± 4,0 71 ,2 ± 5,3 69,1 ± 2,2 67, 8 ± 4,4 74 ,5 ± 3,4 74 ,2 ± 2,8 72 ,9 ± 2,9 53,2 ± 4,0 * WT and...
  • 22
  • 475
  • 0
Báo cáo khoa học: Muramyl-dipeptide-induced mitochondrial proton leak in macrophages is associated with upregulation of uncoupling protein 2 and the production of reactive oxygen and reactive nitrogen species docx

Báo cáo khoa học: Muramyl-dipeptide-induced mitochondrial proton leak in macrophages is associated with upregulation of uncoupling protein 2 and the production of reactive oxygen and reactive nitrogen species docx

Báo cáo khoa học

... rate B 100 101 PI 102 103 A 104 MB (100 lgÆmL)1) 100 ± 112 ± 14.2 1 07 ± 10. 8 95.68 ± 4.6 LPS (1 lgÆmL)1) 100 ± 1.5 102 ± 12.3 98 ± 7. 6 98. 27 ± 8.2 100 101 102 103 Annex-FITC 104 100 101 102 103 ... electron transport chain J Biol Chem 277 , 4 478 4–4 479 0 Lefrancier P, Choay JP, Derrien M & Lederman I (1 977 ) Synthesis of N-acetyl-muramyl-L-alanyl-D-iso- FEBS Journal 278 (2011) 3054–3064 ª 2011 The ... homogenizer in isolation medium consisting of 250 mm UCP2 modulates MDP-induced mitochondrial inefficiency sucrose, mm Tris ⁄ HCl (pH 7. 4) and mm EGTA The homogenate was centrifuged at 104 7 g for The...
  • 11
  • 430
  • 0
Báo cáo khoa học: Structure, regulation and evolution of Nox-family NADPH oxidases that produce reactive oxygen species pptx

Báo cáo khoa học: Structure, regulation and evolution of Nox-family NADPH oxidases that produce reactive oxygen species pptx

Báo cáo khoa học

... 67 68 69 70 71 72 73 74 75 76 77 78 79 nism of Ca2+ activation of the NADPH oxidase (NOX5) J Biol Chem 279 , 18583–18591 Grasberger H, De Deken X, Miot F, Pohlenz J & Refetoff S (20 07) Missense ... FEBS 3 275 Structure, regulation and evolution of Nox 176 177 178 179 180 181 182 183 184 185 3 276 H Sumimoto and of p47phox: conversion of a pagan NADPH oxidase to monotheism J Biol Chem 277 , 18605–18 610 ... p47phox, p67phox and Rac as cytosolic regulators, p47phox is dispensable for cell-free activation in the presence of excess amounts of p67phox and Rac [99 ,100 ] It is thus considered that p47phox...
  • 29
  • 618
  • 0
Báo cáo y học:

Báo cáo y học: "Reactive oxygen species induce expression of vascular endothelial growth factor in chondrocytes and human articular cartilage explants" pps

Báo cáo khoa học

... arthritis [26] It is obvious that tissues other than cartilage are participating in these processes, especially the surrounding synovial tissue This reflects the findings of Felson and coworkers [ 27] , ... knee joints Ann Rheum Dis 2001, 60 :1 07 0 -1 07 3 Enomoto H, Inoki I, Komiya K, Shiomi T, Ikeda E, Obata K, Matsumoto H, Toyama Y, Okada Y: Vascular endothelial growth factor isoforms and their receptors ... articular chondrocytes Ann Rheum Dis 2003, 62 :105 4 -106 0 Cerimele F, Brown LF, Bravo F, Ihler GM, Kouadio P, Arbiser JL: Infectious angiogenesis: Bartonella bacilliformis infection results in endothelial...
  • 8
  • 332
  • 0
Bone Metabolism: The Role of STAT3 and Reactive Oxygen Species

Bone Metabolism: The Role of STAT3 and Reactive Oxygen Species

Y khoa - Dược

... plagiarism and all materials appearing in this thesis/dissertation have been properly quoted and attributed I certify that all copyrighted material incorporated into this thesis/dissertation is in ... Measurement 17 2.6 Biomechanical Testing 17 2 .7 Histomorphometry 17 2.8 Cell Culture 19 2.9 FSS Studies 19 2 .10 Western Blot Analysis ... exercise in mice; this stimulates bone remodeling and osteoblasts to form new bone (11) 1.5 Disruptions in Bone Homeostasis When one type of cell becomes more active than the other, the homeostasis...
  • 73
  • 255
  • 0
Báo cáo y học:

Báo cáo y học: " Helicobacter pylori induces mitochondrial DNA mutation and reactive oxygen species level in AGS cells"

Y học thưởng thức

... 2.33±0. 47 3.03±0.51 260. 67 18 .70 52.00±16.09 148. 67 33.50a 2.00±0 3.03±0.51 272 .00±11.86 166.00±39.59 473 .00±63.51b,f Duration of stimulation (h) 12 2. 67 0. 47 2. 67 0. 47 3.03±0.51 3. 37 0.59 284. 67 17. 42 ... 2. 67 0. 47 3.03±0.51 3. 37 0.59 284. 67 17. 42 300. 67 23 .79 316. 67 49.60 475 .33±59.01j 79 6. 67 71 .53c,g 1149.00±161.28d,h 24 2. 67 0. 47 3. 37 0.59 310. 67 24.01 880.33±80.69k 1409.33±182.92e,i Note: a: ... 1415±1 47 Negative con- 1484±166 trol Positive con- 77 3±82 trol 11638M 8 07 86 11638 75 0±82a Duration (h) 12 24 1482±153 14 27 162 1564±164 1 474 ±139 1 571 ± 172 1 378 ±148 1623± 175 1568±151 816±93 848±80 75 9 73 ...
  • 12
  • 557
  • 2
Báo cáo khoa học: Neuroglobin and cytoglobin expression in mice Evidence for a correlation with reactive oxygen species scavenging doc

Báo cáo khoa học: Neuroglobin and cytoglobin expression in mice Evidence for a correlation with reactive oxygen species scavenging doc

Báo cáo khoa học

... morphologically distinct: further evidence for an apoptosis–necrosis continuum J Comp Neurol 378 , 88 104 FEBS Journal 274 (20 07) 1312–13 17 ª 20 07 The Authors Journal compilation ª 20 07 FEBS 13 17 ... levels comparable with normoxia This finding was expected, as it is reoxygenation, FEBS Journal 274 (20 07) 1312–13 17 ª 20 07 The Authors Journal compilation ª 20 07 FEBS 1313 Neuroglobin as ROS scavenger? ... explanation for why the retina is capable of tolerating an almost 10 times longer period of ischemia than brain They described how the presence of hypoxia in the retina is consistent with the finding...
  • 6
  • 391
  • 0
Báo cáo khoa học: Is there more to aging than mitochondrial DNA and reactive oxygen species? pot

Báo cáo khoa học: Is there more to aging than mitochondrial DNA and reactive oxygen species? pot

Báo cáo khoa học

... 2009 FEBS M F Alexeyev 100 101 102 103 104 105 106 1 07 108 109 110 111 112 113 sites takes place by single-nucleotide insertion and long-patch DNA synthesis DNA repair 7, 605–616 Liu P, Qian ... (2009) 576 8– 578 7 ª 2009 The Author Journal compilation ª 2009 FEBS 578 5 mtDNA + ROS = Aging? 176 177 178 179 180 181 182 183 184 185 186 1 87 188 M F Alexeyev factor-alpha-induced apoptosis J Biol ... Friedberg EC (1 974 ) The absence of a pyrimidine dimer repair mechanism in 578 2 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 mammalian mitochondria Proc Natl Acad Sci USA 71 , 277 7– 278 1 Clayton DA,...
  • 20
  • 523
  • 0
Báo cáo Y học: Inactivation of the Na+-translocating NADH:ubiquinone oxidoreductase from Vibrio alginolyticus by reactive oxygen species pot

Báo cáo Y học: Inactivation of the Na+-translocating NADH:ubiquinone oxidoreductase from Vibrio alginolyticus by reactive oxygen species pot

Báo cáo khoa học

... Biol Chem 270 , 1 976 7–1 977 7 Ackrell, B.A.C., Johnson, M.K., Gunsalus, R.P & Cecchini, G (1992) Structure and function of succinate dehydrogenase and fumarate reductase Chemistry and Biochemistry of ... bacterium, Vibrio alginolyticus, in relation to the primary Na+ pump Biochim Biophys Acta 76 7, 470 – 478 10 Dimroth, P (19 97) Primary sodium ion translocating enzymes Biochim Biophys Acta 1318, 11–51 11 ... Tokuda, H & Unemoto, T (1984) Na+ is translocated at NADH:quinone oxidoreductase segment in the respiratory chain of Vibrio alginolyticus J Biol Chem 259, 77 85 77 90 Imlay, J.A (1995) A metabolic...
  • 6
  • 307
  • 0
báo cáo khoa học:

báo cáo khoa học: "Reactive oxygen species-mediated apoptosis contributes to chemosensitization effect of saikosaponins on cisplatin-induced cytotoxicity in cancer cells" pdf

Báo cáo khoa học

... cytometry analysis Early apoptosis is defined by Annexin V+/PIstaining (Q4) and late apoptosis is defined by Annexin V+/PI+ staining (Q2) (C) and (D) HeLa cells were treated with cisplatin (8 μM) ... 8( 17) : 277 9-88 15 Lopez G, Liu J, Ren W, et al: Combining PCI-2 478 1, a novel histone deacetylase inhibitor, with chemotherapy for the treatment of soft tissue sarcoma Clin Cancer Res 2009, 15 (10) :3 472 -83 ... thus is a potent inducer of cell cycle arrest and apoptosis in most cancer cell types [10] However, a major limitation of cisplatin chemotherapy is that many tumors either are inherently resistant...
  • 8
  • 395
  • 0
Báo cáo y học:

Báo cáo y học: " Early The tripeptide feG regulates the production of intracellular reactive oxygen species by neutrophils" pps

Báo cáo khoa học

... anaphylaxis Dig Dis Sci 19 97, 42(11):2 378 -2383 Mathison RD, Befus AD, Davison JS: A novel submandibular gland peptide protects against endotoxic and anaphylactic shock Am J Physiol 19 97, 273 (3 Pt ... Mathison R, Woodman R, Davison JS: Regulation of leukocyte adhesion to heart by the tripeptides feG and feG(NH2) Can J Physiol Pharmacol 2001, 79 (9) :78 5 -79 2 Turesin F, Sadr A, Davison JS, Mathison ... digestion Oral Dis 2002, 8(3):1 17- 129 Mathison R, Davison JS, Befus AD: Neuroendocrine regulation of inflammation and tissue repair by submandibular gland factors Immunol Today 1994, 15(11):5 27- 532 Rougeot...
  • 9
  • 214
  • 0
Báo cáo khoa học:

Báo cáo khoa học: "A Reactive oxygen species: toxic molecules or spark of life" docx

Báo cáo khoa học

... 2000, 97: 975 3- 975 8 Cowley HC, Bacon PJ, Goode HF, Webster NR, Jones JG, Menon DK: Plasma antioxidant potential in severe sepsis: a 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 ... 2004, 2 87: R1014-R1030 Geiszt M, Leto TL: The Nox family of NAD(P)H oxidases: host defense and beyond J Biol Chem 2004, 279 :5 171 5-5 171 8 Nisimoto Y, Motalebi S, Han CH, Lambeth JD: The p 67( phox) ... number not for citation purposes) Critical Care 74 75 76 77 78 Vol 10 No Magder edge: direct interaction of TLR4 with NAD(P)H oxidase isozyme is essential for lipopolysaccharide-induced producκ...
  • 8
  • 226
  • 0
Báo cáo y học:

Báo cáo y học: "Endogenous TGF-β activation by reactive oxygen species is key to Foxp3 induction in TCR-stimulated and HIV-1-infected human CD4+CD25- T cells" docx

Báo cáo khoa học

... activationinduced T cell apoptosis Immunity 1999, 10: 73 5 -74 4 Barcellos-Hoff MH, Dix TA: Redox-mediated activation of latent transforming growth factor-beta Mol Endocrinol 1996, 10: 1 077 -108 3 Chen W, Frank ... smaller (Fig 7A, R2 green) and stained positive for Annexin-V and 7- AAD (Fig 7C) They exhibited higher MFI of ROS (Fig 7B) than that of live (Annexin-V -7- AAD) or early apoptotic (Annexin +7- AAD-) cells ... vs 18%) (Fig 10A) Consistent with the data of uninfected CD25- T cells (Fig 5), neutralization of TGF-β Page 10 of 16 (page number not for citation purposes) Retrovirology 20 07, 4: 57 http://www.retrovirology.com/content/4/1/57...
  • 16
  • 250
  • 0

Xem thêm