9 vegf and pcna expression in residual hepatic vx2 carcinoma tissues

... staining for Oct4 and Sox2 expression in hypopharyngeal squamous cell carcinoma Brown grains represent a positive signal (3, 3-diaminobenzidine staining) The positive expression site of Oct4 and ... Positive staining for Oct4 and Sox2, mainly localized in the nucleus, were observed in the cancer cells of tumor tissues (Fig 1) The distribution of immunostaining Figure Expression of Oct4 and Sox2 ... ratio 95 %CIa Oct4 expression 0. 296 0.1 290 .6 79 Sox2 expression 0.855 0.4771.532 a b LRC P b P Odds ratio 95 %CIa b 0.004 0.183 0.0400.475 0.001 0. 599 1.2 39 0.6812.254 0.485 CI, Confidence interval...

Ngày tải lên: 18/06/2014, 16:20

... positive MMP9, VEGF and PCNA tumor cells in group I was even higher (P < 0.05) MMP -9, VEGF and PCNA expression in residual hepatic VX2 carcinoma tissues Expression of MMP -9 in tumor tissues was ... of 10 Figure Immunohistochemical staining for MMP -9, VEGF and PCNA in residual hepatic VX2 carcinoma tissues Original magnifications: MMP -9 and VEGF, ×400; PCNA, ×200 A, control group; B, group ... visualized by incubating the samples in 3,3’-diaminobenzedine Finally, the slides were counterstained with hematoxylin To evaluate the expression of MMP -9, VEGF and PCNA, all slides were examined and scored...

Ngày tải lên: 18/06/2014, 16:20

... localization of integrin-linked kinase is regulated by the PINCHbinding ANK repeats J Cell Sci 199 9, 112(Pt 24):45 89- 4 599 Li Y, Yang J, Dai C, Wu C, Liu Y: Role for integrin-linked kinase in mediating tubular ... c-Myc, VEGF, and SOX -9 mRNA expression VEGF, c-Myc, and SOX -9 are all involved in AC proliferation and differentiation Therefore, we next determined whether mRNA expression for c-Myc, VEGF, and ... Mechanical signals control SOX -9, VEGF, and c-Myc expression and cell proliferation during inflammation via integrinlinked kinase, B-Raf, and ERK1/2-dependent signaling in articular chondrocytes Arthritis...

Ngày tải lên: 12/08/2014, 14:21

... expressed in highly metastatic mammary adenocarcinoma cell lines cDNA cloning, expression, and protein analyses J Biol Chem 199 4, 2 69( 37):2 295 8-63 Jangq KS, Paik SS, Chung H, Oh YH, Konq G: MTA1 overexpression ... silence and consequentially recover the protein expression of ER alpha, resulting in increase sensitivity of antiestrogens, as well as suppress the protein expression of MMP -9 and cyclinD1 in ER-negative ... ShRNA-mediated gene silencing of MTA1 influenced on protein expression of ER alpha, MMP -9, CyclinD1 and invasiveness, proliferation in breast cancer cell lines MDA-MB-231 and MCF7 in vitro Journal of...

Ngày tải lên: 10/08/2014, 10:21

... from both brain and intestine in L maderae [14,15] The finding that N-terminally extended TKRPs are predominantly expressed only in the gut and not in the brain are in line with findings of enrichment ... tachykinin and insect kinin ⁄ Tyr-W-MIF neuropeptide family pairs Ann NY Acad Sci 897 , 388–400 Nassel DR ( 199 9) Tachykinin-related peptides in inver¨ tebrates: a review Peptides 20, 141–158 Vanden ... Swinnen E, Ferket K & De Loof A ( 199 9) Tachykininlike peptides and their receptors; a review Ann NY Acad Sci 897 , 374–387 Satake H, Kawada T, Nomoto K & Minakata H (2003) Insight into tachykinin-related...

Ngày tải lên: 20/02/2014, 01:20

... long chain fatty acids (Elovl3), type iodothyronine deiondinase (Dio2), homeobox C9 (Hoxc9), insulin-like growth factor binding protein (Igfbp3), dermatopontin (Dpt), and b-actin are showed in Table ... reduced in both eWAT and iBAT in response to PM2.5 exposure Recent studies have implicated PM2.5 in increased adipose inflammation and insulin resistance [11,12], and epidemiological studies indicate ... Stiles AD, D’Ercole AJ: Expression of insulinlike growth factor-I (IGF-I) and IGF-binding proteins during adipogenesis Endocrinology 199 4, 135:1863-1868 29 Gesta S, Bluher M, Yamamoto Y, Norris...

Ngày tải lên: 06/03/2014, 19:20

... (2006) Neuroglobin and cytoglobin: oxygen-binding proteins in retinal neurons Invest Ophthalmol Vis Sci 47, 1016–1023 Stein I, Itin A, Einat P, Skaliter R, Grossman Z & Keshet E ( 199 8) Translation ... differentially regulates the expression of neuroglobin and cytoglobin in rat brain Brain Res 1 096 (1), 173–1 79 Schmidt M, Gerlach F, Avivi A, Laufs T, Wystub S, Simpson JC, Nevo E, Saaler-Reinhardt S, Reuss ... detection and protein level was studied in second order As can be seen in Fig 3, in eyes, during hypoxic incubation, H2O2 production remained at levels comparable with normoxia This finding was...

Ngày tải lên: 23/03/2014, 09:21

... adenocarcinoma cell lines (Bic-1 and Seg-1), human gastric adenocarcinoma cell lines (AGS, AZ521 and KATOIII), colorectal adenocarcinoma cell lines (Caco-2 and DLD1), a human cervix epithelioid carcinoma ... was fixed in 10% formalin and embedded in paraffin for histopathology The paraffinembedded biopsy specimens were cut into 5-μm-thick sections and stained with hematoxylin and eosin, and the three ... expression in squamous cell carcinoma and adenocarcinoma of the esophagus: associations with survival Clin Cancer Res 20 09, 15:6 192 -200 Orringer MB: Multimodality therapy for esophageal carcinoma...

Ngày tải lên: 18/06/2014, 19:20

... hypopharynx/larynx 12 (100%) Indeterminate 0 .99 8 10 (100%) 31 (66.0%) (0%) 16 (34.0%) 0.048* Indeterminate 0 .99 8 0.170 Age female 0.53 (0.07, 3.65) 1.000 0.520 Indeterminate 1.000 Tumor Site 0.0 49* Stage IVa ... DNA-dependent protein kinase and EGFR and then delayed the DNA repair [37- 39] Oxaliplatin induced double-strand breaks [40] When cetuximab was combined with oxaliplatin, cetuximab reduced the expression ... Characteristics of mutations in the p53 gene in oral squamous cell carcinoma associated with betel quid chewing and cigarette smoking in Taiwanese Carcinogenesis 2001, 22:1 497 -1503 Adelstein DJ, Li Y, Adams...

Ngày tải lên: 18/06/2014, 19:20

... Neuroinflammation 2005, 2:27 http://www.jneuroinflammation.com/content/2/1/27 Findings Aberrant expression of cyclins, cyclin dependent kinases (CDKs) and their inhibitors has been observed in ... to potentially induce COX-2 and cell cycle protein expression in vitro [3,11-13] It has been shown that interleukin-1β induces COX-2 expression in neuronal cell models [11,12] and conditioned ... Boehringer M, Hull M: Interleukin-1beta induces cyclooxygenase-2 and prostaglandin E(2) synthesis in human neuroblastoma cells: involvement of p38 mitogenactivated protein kinase and nuclear factor-kappaB...

Ngày tải lên: 19/06/2014, 22:20

... Interleukin 12; IL-13: Interleukin 13; IL-13rα1: Interleukin 13 receptor alpha 1; IL-15: Interleukin 15; IL-16: 19 ` Interleukin 16; IL-17B: Interleukin 17B; IL-18: Interleukin 18; IL-1F5: Interleukin ... gene expression of 84 cytokines, chemokines, and their receptors in the brain and spleen was examined by relative quantitative PCR using a PCR array, and protein levels in the brain, spleen, and ... beta; IL-2rγ: Interleukin receptor, gamma; IL-3: Interleukin 3; IL-4: Interleukin 4; IL-5: Interleukin 5; IL-5rα: Interleukin receptor, alpha; IL-6: Interleukin 6; IL-6rα: Interleukin receptor,...

Ngày tải lên: 19/06/2014, 22:20

... hypopharynx/larynx 12 (100%) Indeterminate 0 .99 8 10 (100%) 31 (66.0%) (0%) 16 (34.0%) 0.048* Indeterminate 0 .99 8 0.170 Age female 0.53 (0.07, 3.65) 1.000 0.520 Indeterminate 1.000 Tumor Site 0.0 49* Stage IVa ... DNA-dependent protein kinase and EGFR and then delayed the DNA repair [37- 39] Oxaliplatin induced double-strand breaks [40] When cetuximab was combined with oxaliplatin, cetuximab reduced the expression ... Characteristics of mutations in the p53 gene in oral squamous cell carcinoma associated with betel quid chewing and cigarette smoking in Taiwanese Carcinogenesis 2001, 22:1 497 -1503 Adelstein DJ, Li Y, Adams...

Ngày tải lên: 20/06/2014, 03:20

... was more common in rectal carcinomas than in nonrectal colon carcinomas ( 89% versus 70%, χ2=6.8 39; p=0.0 09) and in low grade carcinomas than in high grade carcinomas (91 % versus 55%, χ2 = 17,247; ... CK20 in colorectal adenocarcinomas, gastric adenocarcinomas and pancreatic adenocarcinomas CK7 and CK20 CK7 expression was detected in 22% (26/118) of colorectal, in 80% (47/ 59) of gastric, and in ... Cytokeratin immunostaining in differentiating primary ovarian carcinoma from metastatic colonic adenocarcinoma Mod Pathol 199 6, 9: 1040–1044 18 Loy TS, Calaluce RD: Utility of cytokeratin immunostaining...

Ngày tải lên: 21/06/2014, 19:20

... rats were found to express nestin and/ or vimentin in rats with EAE This finding is in part Embryonic Intermediate Filaments, Nestin and Vimentin, Expression in the Spinal Cords of Rats with Experimental ... reported vimentin expression in astrocytes and macrophages in EAE lesions [4], and nestin expression in astrocytes and ependymal cells in EAE lesions [3] The latter focused on the remyelination capacity ... acidic protein and vimentin in reactive astrocytes following brain injury in rats Brain Res 199 1, 566(1-2), 333-336 Calza , L., Fe rn a n de z, M., Giu lian i, A., Alo e , L a n d Gia rd in o, L...

Ngày tải lên: 07/08/2014, 17:22

... chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions J Clin Invest 199 8, 101:746754 Murdoch C, Finn A: Chemokine receptors and their role in inflammation ... NW, Kunkel SL: Chemokines and their role in disease Int J Clin Lab Res 199 8, 28 :91 -95 Tuschil A, Lam C, Haslberger A, Lindley I: Interleukin-8 stimulates calcium transients and promotes epidermal ... patients within Table Staining of the indicated proteins on parallel blots is shown Equal loading of tissue extracts was controlled by β-actin protein staining MW indicates a protein from ECL...

Ngày tải lên: 09/08/2014, 01:23

... minutes, and 72°C for minute [35 cycles]; β-actin: 94 °C for 0.5 minutes, 56°C for 0.5 minutes, and 72°C for minute [35 cycles]) was performed in a DNA engine cycler (MJ Research, Inc., Watertown, MA, ... pathways involved in TWEAKinduced RANTES production in MC3T3-E1 cells, we examined the effects of several inhibitors on TWEAK-induced RANTES production in MC3T3-E1 cells Helenalin (an inhibitor ... inhibited BMP-Smad signaling by inducing serine phosphorylation of the linker region of Smad proteins, resulting in the blockade of Smad nuclear translocation in a certain cell type [22] It is...

Ngày tải lên: 09/08/2014, 08:22

... Tlr12 Toll-like receptor 12 3.3 3815 49 Zfp 69 Zinc finger protein 69 3.2 3.3 2307 79 Serinc2 Serine incorporator 2.2 16818 Lck Lymphocyte protein tyrosine kinase 2 .9 12260 C1qb Complement component ... protein 54 (Tmem54), coiled coil domain containing 28B (Ccdc28b) and testis-specific serine kinase (Tssk3) all to be downregulated Furthermore, we found zink finger and BTB domain containing (Zbtb8) ... 1 .9 1.6 20720 Serpine2 Serine (or cysteine) peptidase inhibitor, clade E, member 1.8 14700 Gng10 Guanine nucleotide binding protein (G protein), gamma 10 230657 Tmem 69 Transmembrane protein 69...

Ngày tải lên: 09/08/2014, 10:21

... patterns of neurotrophins and neurotrophin receptors in articular chondrocytes and inflammatory infiltrates in knee joint arthritis Cells Tissues Organs 2008, 188: 299 -3 09 Rihl M, Kruithof E, ... determined in the SF cells are depicted in Table and outlined in detail by scatter plots in Figure (ligands) and Figure (receptors) As for the transcripts encoding the ligands, BDNF revealed high expression ... mitogen-activated protein kinase pathway involving the c-jun N-terminal, the p38, and the extracellular-regulated protein kinases (ERK1/2) all of which have been identified in arthritis as well Interestingly,...

Ngày tải lên: 09/08/2014, 14:21

... years in men and 62.8 ± 3.4 years in women Cirrhosis etiology was alcohol in 13 patients, HBV infection in 9, HCV infection in 1, combined alcohol and HBV infection in and combined alcohol and ... Endocrinol 199 1, 79( 1–3):C153-C158 Skene DJ, Lockley SW, Arendt J: Use of melatonin in the treatment of phase shift and sleep disorders Adv Exp Med Biol 199 9, 467: 79- 84 Arendt J: Melatonin in humans: ... Clinical importance of melatonin Prog Brain Res 197 9, 52:5 39- 547 Steindl PE, Finn B, Bendok B, Rothke S, Zee PC, Blei AT: Disruption of the diurnal rhythm of plasma melatonin in cirrhosis Ann Intern...

Ngày tải lên: 10/08/2014, 09:20