8clinical impact of late central nervous system toxicity
báo cáo khoa học: "Isolated angiitis of the central nervous system with tumor-like lesion, mimicking brain malignant glioma: a case report and review of the literature" pdf
Ngày tải lên :
09/08/2014, 02:20
... angiitis of the central nervous system: serial MRI of brain and spinal cord Neuroradiology 2001, 43:599-607 14 Moore PM: Diagnosis and management of isolated angiitis of the central nervous system ... presentation of primary angiitis of the central nervous system Ann Rheum Dis 2008, 67:1732-1735 doi:10.1186/1477-7819-9-97 Cite this article as: You et al.: Isolated angiitis of the central nervous system ... Isolated Angiitis of the Central Nervous System: a Case Report and Review CNS Spectrums 2008, 13:209-213 Page of 10 Ozawa T, Sasaki O, Sorimachi T, Tanaka R: Primary angiitis of the central nervous...
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Characterization of MP2 cell division and pins function on spindle asymmetry of drosophila central nervous system
Ngày tải lên :
12/09/2015, 09:55
... CHARACTERIZATION OF MP2 CELL DIVISION AND PINS FUNCTION ON SPINDLE ASYMMETRY OF DROSOPHILA CENTRAL NERVOUS SYSTEM LIN SHUPING (M.Sc.) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF ... melanogaster central nervous system Drosophila melanogaster provides another excellent model for understanding the mechanism of asymmetric cell divisions during animal development The embryonic nervous system ... asymmetric cell divisions regulate the ability of cells to maintain the stem cell fate versus acquiring different fate, particularly in the vertebrate nervous system However, most of our mechanistic insights...
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Báo cáo y học: "The impact of therapy for childhood acute lymphoblastic leukaemia on intelligence quotients; results of the risk-stratified randomized central nervous system treatment trial MRC UKALL XI" ppsx
Ngày tải lên :
10/08/2014, 21:23
... inherent genetic susceptibility, drug toxicity, time out of full-time education or particular vulnerability of certain individuals to the impact of chronic illness Page of 12 Pharmacogenomic and genome ... as: Halsey et al.: The impact of therapy for childhood acute lymphoblastic leukaemia on intelligence quotients; results of the risk-stratified randomized central nervous system treatment trial ... hours after the start of the HDM infusion) may have reduced late effects of HDM Both of these factors would have been expected to widen any gap between HDM and XRT in terms of adverse effects These...
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Báo cáo y học: "Gene expression atlas of the mouse central nervous system: impact and interactions of age, energy intake and gender" pdf
Ngày tải lên :
14/08/2014, 08:20
... CNSand and age-related Table S5d energy Table of Table DIANE Figure previous 1.0 the of categories genes Abbreviations AAG, aging-associated gene; AL, ad libitum; CNS, central nervous system; CR, ... use of arrays that included relatively small numbers of genes Different regions of the CNS exhibit unique transcriptomes that are independent of gender, age and energy intake The design of our ... region of the CNS exhibits a unique pattern of gene expression Gene expression profiles were generated for each of the five brain regions (5 mice × ages × genders × diets), resulting in a total of...
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Cancer of the Brain and Other Central Nervous System doc
Ngày tải lên :
22/03/2014, 17:20
... 76.7 69.5 63.7 60.6 Other Central Nervous System National Cancer Institute 205 SEER Survival Monograph Chapter 25 Cancer of the Brain and Nervous System Table 25.3: Cancer of the Brain: Race, Sex, ... Institute 211 SEER Survival Monograph Chapter 25 Cancer of the Brain and Nervous System Table 25.9: Cancer of the Other Central Nervous System Cancer: 1-, 2-, 3-, 5-, 8-, & 10-Year Relative Survival ... lesion of brain Brain, NOS * National Cancer Institute NOS, Not Otherwise Specified 210 SEER Survival Monograph Chapter 25 Cancer of the Brain and Nervous System Table 25.7: Cancer of the Other Central...
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báo cáo hóa học: " Temporal expression and cellular origin of CC chemokine receptors CCR1, CCR2 and CCR5 in the central nervous system: insight into mechanisms of MOG-induced EAE" pptx
Ngày tải lên :
19/06/2014, 22:20
... Hesselgesser J, Horuk R, Sellebjerg F, Lassmann H, Ransohoff RM: CCR1+/CCR5+ mononuclear phagocytes accumulate in the central nervous system of patients with multiple sclerosis Am J Pathol 2001, ... Sellebjerg F, Strieter RM, Frederiksen JL, Ransohoff RM: Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients J Clin Invest 1999, ... Lassmann H, Ransohoff RM: Chemokine receptors on infiltrating leucocytes in inflammatory pathologies of the central nervous system (CNS) Neuropathol Appl Neurobiol 2003, 29:584-95 Ransohoff RM, Tani...
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Báo cáo sinh học: "The long term effects of chemotherapy on the central nervous system" docx
Ngày tải lên :
06/08/2014, 18:21
... Adornato BT, DiChiro G: Abnormal CT scans of the brain in asymptomatic children with acute lymphocytic leukemia after prophylactic treatment of the central nervous system with radiation and intrathecal ... no longer valid Further evidence of the development of methotrexateinduced leukoencephalopathy in the absence of cranial radiation was shown in a German study of infants with medulloblastoma treated ... needs to be paid to the long term follow-up of both children and adults who receive this form of therapy Journal of Biology 2006,5:21 21.4 Journal of Biology 2006, Volume 5, Article 21 Duffner...
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Báo cáo sinh học: "Systemic 5-fluorouracil treatment causes a syndrome of delayed myelin destruction in the central nervous system" doc
Ngày tải lên :
06/08/2014, 18:21
... al 12.9 (b) Change of latency P2-P1 0.3 0.2 Change of latency P3-P1 Ctrl 5-FU 0.1 -0.0 -0.1 Clicks at 80 dB n=4 -0.2 -0.3 Day Day Day 14 Change of latency P3-P1 (ms) Change of latency P2-P1 (ms) ... lack of effect of 5-FU treatment on DPOAEs, comparison of the changes in inter-peak latencies P2-P1 and P3-P1 with those of a sham-treated control group revealed that at the later time points of ... 49:542-554 113 Tofilon PJ, Fike JR: The radioresponse of the central nervous system: a dynamic process Radiat Res 2000, 153:357-370 114 Hopewell JW, Withers HR: Late effects of radiation are...
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Báo cáo khoa học: "Immunohistochemical study of constitutive neuronal and inducible nitric oxide synthase in the central nervous system of goat with natural listeriosis" potx
Ngày tải lên :
07/08/2014, 14:23
... Magnification A and B, ×66 C and D, ×132 Immunohistochmical study of nitric oxide synthase in the central nervous system of goat Enhanced expression of nNOS and iNOS in L monocytogenes-infected brain At ... and autoimmune disease of the central nervous system Proc Natl Acad Sci U.S.A 1995, 92, 5312-5316 Johnson, G.C., Fales, W.H., Maddox, C.W and RamosVara, J.A Evaluation of laboratory test for ... terms of neuronal staining for iNOS in caprine listeriosis compared with the previous bovine study [6] We prefer to postulate that the differences are due to the different detection system of immunostaining...
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Báo cáo khoa học: " Experimental concepts for toxicity prevention and tissue restoration after central nervous system irradiation" ppt
Ngày tải lên :
09/08/2014, 10:21
... radiation Schematicin cancer of the time of the central nervous system Figure (CNS) via portals exposing some part course of radiation-induced Schematic concept of the time course of radiation-induced ... the central nervous system: an interpretation of target cell responses Br J Cancer 1986, 53(Suppl 7):207-217 Schultheiss TE, Kun LE, Ang KK, Stephens LC: Radiation response of the central nervous ... might Page of 10 (page number not for citation purposes) Radiation Oncology 2007, 2:23 http://www.ro-journal.com/content/2/1/23 Table 1: Overview of experimental studies of central nervous system...
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Báo cáo y học: "Cerebrospinal fluid neopterin: an informative biomarker of central nervous system immune activation in HIV-1 infection" ppt
Ngày tải lên :
10/08/2014, 05:21
... neopterin, in particular One of these again parallels considerations of systemic HIV disease and relates to the renewed appreciation of the importance of immune activation in systemic disease pathogenesis ... neopterin concentrations in the different stages of systemic HIV infection and HIV-related neurological disease in untreated patients and the impact of treatment To examine and illustrate these issues, ... monoxygenases [30,31] BH4 is also cofactor of the cytokine-inducible enzyme nitric oxide synthase (iNOS), one of the most important cytotoxic reactions of macrophages stimulated by IFN-γ However, in...
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báo cáo khoa học: "In vivo observation of gold nanoparticles in the central nervous system of Blaberus discoidalis" potx
Ngày tải lên :
11/08/2014, 00:22
... nanoparticles in the central nervous system of Blaberus discoidalis Journal of Nanobiotechnology 2011 9:5 Submit your next manuscript to BioMed Central and take full advantage of: • Convenient online ... Journal of Comparative Neurology 1992, 322:1-15 10 Colwell CS, Page TL: A circadian rhythm in neural activity can be recorded from the central nervous system of the cockroach Journal of Comparative ... into the nervous system and to conduct in situ characterization There were 67% of treated roaches and 78% of untreated roaches alive after two months of treatment which indicates no major impact...
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báo cáo khoa học: "Extensive central nervous system involvement in Merkel cell carcinoma: a case report and review of the literature" docx
Ngày tải lên :
11/08/2014, 03:20
... other types of brain metastases, on the number of metastases, systemic spread of the disease and the accessibility to surgery We believe that the CNS metastases of MCC are an expression of a hematogenous ... Extensive central nervous system involvement in Merkel cell carcinoma: a case report and review of the literature Journal of Medical Case Reports 2011 5:35 Submit your next manuscript to BioMed Central ... before the detection of intradural metastasis Consistent with other reports of poor prognosis of intraspinal metastases [12,13,16], our patient showed evidence of progressive systemic metastatic...
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Báo cáo y học: "Ischemia as a possible effect of increased intraabdominal pressure on central nervous system cytokines, lactate and perfusion pressures" ppsx
Ngày tải lên :
13/08/2014, 20:21
... threshold of 60 mmHg, which was followed by a decrease in all ischemia indicators, irrespective of the presence of even higher IAP Improvement of CNS perfusion was a result of an increase of MAP, ... effect of increased intra-abdominal pressure on central nervous system cytokines, lactate and perfusion pressures Critical Care 2010 14:R31 Page 10 of 10 Submit your next manuscript to BioMed Central ... threshold for ischemia of 60 mmHg [24] Paradoxically, further increase of IAP to 45 mmHg was followed by a minor increase of ICP and a decrease of ISP, with a concomitant improvement of perfusion pressures...
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Báo cáo y học: "MicroRNAs show a wide diversity of expression profiles in the developing and mature central nervous system" docx
Ngày tải lên :
14/08/2014, 08:20
... Predictions of miRNA targets For predictions of possible mRNA targets of miRNAs, we used prediction programs and related resources available at [39,40] Abbreviations CNS, central nervous system; ... majority of CNS cells and from transient to constitutive expression We describe several classes of expression profile and discuss these in terms of known and predicted modes of action of miRNAs ... importance of miRNAs in brain development, function and disease, we still have little idea of the range of miRNA activities in neural cells Given the known modes of action of miRNAs, knowledge of the...
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The role of hydrogen sulfide in the central nervous system implications in the treatment of alzheimers disease
Ngày tải lên :
09/09/2015, 08:17
... institutionalization of patients An additional impact of AD is on the day to day activity of patients (activities of daily living) These symptoms result in adverse effects of quality of life, impact on ... chemical properties of H2S 1.1.1.2 Toxicity of H2S 1.1.1.3 Biosynthesis of H2S 1.1.1.4 Storage and metabolism of H2S 1.1.1.5 Biological role of H2S in CNS ... 1.1.1.2 Toxicity of H2S H2S is often a lethal environmental and occupational hazard that has a unique pattern of toxicity It is the second most common cause (at 7.7%, after carbon monoxide at 36%) of...
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Role of central nervous system ceramides and free radicals in a mouse model of orofacial pain
Ngày tải lên :
14/09/2015, 08:42
... 3.3 Role of central nervous system peroxynitrite in a mouse model of orofacial pain 99 Introduction 100 Materials and methods 102 VI Table of Contents ... Table of Contents 2.2 Orofacial pain 16 2.3 Animal model of orofacial pain 17 General introduction of sphingolipids 21 3.1 Structure and classification of sphingolipids ... and central sensitization 1.3.1 Peripheral sensitization 1.3.2 Central sensitization General introduction of orofacial pain 10 2.1 Anatomy basis of orofacial...
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Genetic engineering and surface modification of baculovirus derived vectors for improved gene delivery to the central nervous system
Ngày tải lên :
14/09/2015, 11:28
... contribute to the development of Central Nervous System gene therapies as well as to the progression of various virus- and gene delivery-related studies VII LIST OF PUBLICATIONS Publications: ... In spite of rapid advancement of biomedical science and technology, a number of complicated diseases still remain incurable Many of these unconquered diseases such as Central Nervous System (CNS) ... SURFACE MODIFICATION OF BACULOVIRUS DERIVED VECTORS FOR IMPROVED GENE DELIVERY TO THE CENTRAL NERVOUS SYSTEM YANG YI (B Eng.) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY GRADUATE...
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Development of hybrid promoters and viral vectors for improved gene delivery to the central nervous system
Ngày tải lên :
16/09/2015, 08:30
... the treatment of neurological disorders in the central nervous system (CNS) Because of the complex structure and high vulnerability of the CNS, it is critical that the expression of a therapeutic ... treatment of neurological disorders To achieve this goal, several obstacles to successful gene transfer that are related to unique attributes of the central nervous system (CNS) must be overcome One of ... Ratio of PEI to DNA used for cell transfection was 10 equivalents of PEI nitrogen per DNA phosphate The required amount of PEI was calculated by taking into account that µg of DNA contains nmol of...
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Effects of central nervous system free fatty acids, prostaglandins and lysophospholipids on allodynia in a mouse model of orofacial pain
Ngày tải lên :
05/10/2015, 13:53
... interpretation of pain mechanisms, that is, the existence within the peripheral and central nervous systems (CNS) of a series of neuronal elements concerned solely with the processing of these simple ... the internal capsule to the face area of the postcentral gyrus Orofacial Pain Diagnosis of orofacial pain is complicated because of the region’s density of anatomical structures, rich innervations ... that noxious input to the CNS sets off a central process of enhancement of responsiveness that continues independently of peripheral afferent drive Short periods of electrical stimulation at noxious...
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