8 hemangioblasts and their progeny
Cell Cycle Regulation in Mammalian Germ Cells
Ngày tải lên :
25/10/2013, 21:20
... 271, 277, 284 , 288 , 290, 294, 2 98, 299, 301, 304, 3 08, 310, 312 cyclin D2, 281 , 284 , 288 , 290, 2 98, 3 08 cyclin D3, 240, 243, 288 , 290, 291 Subject Index cyclin E, 8, 1 58, 159, 184 , 185 , 188 , 190, ... 77, 78, 150, 183 – 186 , 188 , 190, 192, 193, 195, 196, 1 98, 199, 205–207, 210, 271– 282 , 284 – 286 , 289 , 291–296, 2 98 301, 304, 307–313, 343, 345, 353–3 58, 360 – Cdc25A, 77, 78 – Cdc7, 78 – Cdk2, 78 – ... 294, 296, 2 98 301, 303–305, 307, 309–313, 334, 335, 353, 354 370 Cdk3, 2 78, 279 Cdk4, 184 , 185 , 188 , 193, 196, 2 08, 232, 259–262, 273, 276, 2 78, 281 , 284 , 285 , 287 , 289 , 290, 294, 297, 2 98, 300,...
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scientific american - 1996 10 - hell's cells
Ngày tải lên :
12/05/2014, 15:15
... her abusive husband and also Sally and her two older brothers The family moved in with Sally’s paternal grandmother Sally’s father was an alcoholic, always in and out of jobs and, because he ... of poor housed mothers and their children into homelessness, despite their efforts to find work Microbes Deep inside the Earth James K Fredrickson and Tullis C Onstott 68 Biologists once viewed ... into the Martian soil and crust and recent work on Earth adds reasons to think so J ames K Fredrickson and Tullis C Onstott explain why in their article, beginning on page 68 Drilling experiments...
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báo cáo hóa học:" Aurora kinase inhibitors synergize with paclitaxel to induce apoptosis in ovarian cancer cells" pot
Ngày tải lên :
18/06/2014, 15:20
... lines, and Merck & Co and Vertex 19 Weaver BA, Cleveland DW: Decoding the links between mitosis, cancer, and chemotherapy: The mitotic checkpoint, adaptation, and cell death Cancer Cell 2005, 8( 1):7-12 ... (INCENP) and aurora B in histone H3 phosphorylation, metaphase chromosome alignment, kinetochore disjunction, and chromosome segregation J Cell Biol 2001, 153(4) :86 5 -88 0 Kallio MJ, McCleland ML, ... 12(4) :85 1 -86 2 Bourguignon LY, Zhu H, Shao L, Chen YW: CD44 interaction with tiam1 promotes Rac1 signaling and hyaluronic acid-mediated breast tumor cell migration J Biol Chem 2000, 275(3): 182 9- 183 8...
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báo cáo hóa học:" KSP inhibitor ARRY-520 as a substitute for Paclitaxel in Type I ovarian cancer cells" potx
Ngày tải lên :
18/06/2014, 15:20
... Protein 88 Nuclear factor κB (TLR-4/MyD 88/ NF-κB) pathway, and the ligation of TLR-4 by Paclitaxel (a known TLR-4 ligand) is able to induce NF-κB activation and secretion of proinflammatory and pro-tumor ... pathway and does not induce the secretion of pro-inflammatory and pro-tumor cytokines in Type I EOC cells Methods Cell lines and culture conditions Established human EOC cell lines, A2 780 and A2 780 / ... functions of NF-kappaB in liver physiology and cancer Cancer Lett 20 08, 267: 182 - 188 Greten FR, Karin M: The IKK/NF-kappaB activation pathway-a target for prevention and treatment of cancer Cancer Lett...
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báo cáo hóa học:" ST6Gal-I expression in ovarian cancer cells promotes an invasive phenotype by altering integrin glycosylation and function" pptx
Ngày tải lên :
20/06/2014, 07:20
... by NIH grant R01CA842 48 (SLB) References Varki NM, Varki A: Diversity in cell surface sialic acid presentations: implications for biology and disease Lab Invest 2007, 87 :85 1 -85 7 Bellis SL: Variant ... acquisition and analysis DRC wrote the manuscript with editorial assistance from JAL III and SLB DRC, SLB and JAL III were responsible for the initial conception and design of the study 18 Acknowledgements ... Acta 19 98, 1379:23- 28 Wang XC, Smith TJ, Lau JT: Transcriptional regulation of the liver beta-galactoside alpha 2,6-sialyltransferase by glucocorticoids J Biol Chem 1990, 265:1 784 9-1 785 3 Vandamme...
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báo cáo hóa học:" Sensitization of ovarian cancer cells to cisplatin by genistein: the role of NF-kappaB" doc
Ngày tải lên :
20/06/2014, 07:20
... Pharmacol 20 08, 588 :1 58- 164 Choi EJ, Kim T, Lee MS: Pro-apoptotic effect and cytotoxicity of genistein and genistin in human ovarian cancer SK-OV-3 cells Life Sci 2007, 80 :1403-14 08 Gossner G, ... assessing apoptosis in A2 780 and C200 cells treated with genistein, cisplatin, taxotere, gemcitabine and their combinations according to the manufacturer's protocol Briefly, A2 780 and C200 cells were ... cisplatin, gemcitabine and taxotere, and the combination treatments on apoptotic cell death Induction of apoptosis by genistein, cisplatin, gemcitabine and taxotere in A2 780 and C200 ovarian cancer...
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báo cáo hóa học:" Trastuzumab Sensitizes Ovarian Cancer Cells to EGFR-targeted Therapeutics" docx
Ngày tải lên :
20/06/2014, 07:20
... 1.000 ± 0.023 1.000 ± 0.1 08 1.000 ± 0.047 Lapatinib μM μM 0.762 ± 0.063 0.645 ± 0.069 0. 789 ± 0.0 98 0.666 ± 0.031 0 .81 9 ± 0. 084 0.673 ± 0.0 48 0 .84 5 ± 0.023 0 .88 9 ± 0. 082 p = 0.001 p = 0.0001 p ... Reagents and cell lines Ovarian carcinoma cell lines A 184 7, A2 780 (and cisplatin-resistant subclones A2 780 CP30 and A2 780 CP70), BG-1, ES-2, MDAH-2774, OVCAR-7, OVCAR-10, PEO1, PEO-4, and UPN-251 ... 1.000 ± 0.010 1.000 ± 0.034 1.000 ± 0.0 08 1.000 ± 0.002 μM 0 .81 2 ± 0.006 0 .82 9 ± 0.040 0.9 98 ± 0.039 0.691 ± 0.026 0.977 ± 0.125 0 .89 9 ± 0.060 0.797 ± 0.060 0 .88 4 ± 0.022 p = 0.001 p = 0.0005 p =...
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báo cáo hóa học:" Curcumin induces chemo/radio-sensitization in ovarian cancer cells and curcumin nanoparticles inhibit ovarian cancer cell growth" pot
Ngày tải lên :
20/06/2014, 07:20
... cisplatin A2 780 CP cells were treated as indicated for a total of 48 hrs and protein lysates were collected and analyzed by immunoblotting for caspase and PARP (D) Bands for full length and cleaved ... understanding regarding the molecular mechanisms involved in curcumin mediated chemo/radio-sensitization in ovarian cancer cells Materials and methods Cell culture and drugs A2 780 and A2 780 CP (resistant ... applications J Am Chem Soc 2007, 129:1 381 0-1 381 1 Gavert N, Ben-Ze'ev A: beta-Catenin signaling in biological control and cancer J Cell Biochem 2007, 102 :82 0 -82 8 Wheelock MJ, Johnson KR: Cadherin-mediated...
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báo cáo hóa học:" Anti-proliferative effect of LXR agonist T0901317 in ovarian carcinoma cells" pptx
Ngày tải lên :
20/06/2014, 07:20
... replicated and contain double DNA content and thus double intensity of fluorescence (G2/M) and cells in S phase Caspase-3 and -7 assay Vybrant FAM Caspase-3 and -7 Assay Kit V351 18, (Molecular ... (Santa Cruz, CA) Anti-p21 (ab7960-1, 1:100), and anti-β actin (ab -82 29, 1:1000) antibodies were from Abcam (Cambridge, MA) Anti-phospho Rb (Ser 80 7 /81 1) (#93 08, 1:1000) was from Cell Signaling Technology ... SKOV3, A2 780 (human ovarian carcinoma cell lines) and HS- 68 (human foreskin fibroblasts) cell lines were obtained from the American Type Culture Collection (Manassas, VA) CaOV3 and HS- 68 cells...
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báo cáo hóa học:" MUC4 stabilizes HER2 expression and maintains the cancer stem cell population in ovarian cancer cells" ppt
Ngày tải lên :
20/06/2014, 07:20
... Nebraska Medical Center, Omaha, NE 681 98- 587 0, USA 2Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE 681 98- 587 0, USA Authors’ contributions ... Institutes of Health (RO1 CA 785 90, CA 131944 and CA133774) and the Susan G Komen Foundation (KG07 082 6) The authors acknowledge the invaluable technical support from Mr Erik Moore and Mrs Kavita Mallya ... have read and approve the final manuscript PPM: Conception and design, collection and/ or assembly of data, data analysis and interpretation, manuscript writing PS.: Experimental help and data...
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báo cáo hóa học:" Gene Expression and Pathway Analysis of Ovarian Cancer Cells Selected for Resistance to Cisplatin, Paclitaxel, or Doxorubicin" docx
Ngày tải lên :
20/06/2014, 08:20
... cycle-dependent cytotoxicity, G2/M phase arrest, and disruption of p34cdc2/cyclin B1 activity induced by doxorubicin in synchronized P 388 cells Mol Pharmacol 1996, 49 :83 2 -84 1 Mendelsohn AR, Hamer JD, Wang ZB, ... from the cell surface and cell movement for cisplatin resistance, proteasome regulation and steroid biosynthesis for doxorubicin resistance, and control of translation and oxidative stress for ... cancer [8- 10] Overall, these studies indicate that a better understanding of the mechanisms of drug action and drug resistance may ultimately lead to new approaches for circumventing resistance and...
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Báo cáo sinh học: "TBP2 is a general transcription factor specialized for female germ cells" doc
Ngày tải lên :
06/08/2014, 19:21
... Akhtar and Veenstra [5] highlight the functional significance of the apparent differentially available pool of TBP and TBP2 in oocytes and provide mechanistic insights into the dynamics of TBP and ... highly flexible and can switch factors depending on the cellular and ontogenic requirements A common model for subfunctionalization of TBP and TBP2 during the transition between oocyte and embryo ... http://jbiol.com/content /8/ 11/97 Müller and Tora: Journal of Biology 2009, 8: 97 97.4 formed [5] In contrast to mammals, a large amount of TBP mRNA is produced maternally and seems to be prevented...
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Báo cáo y học: "On the number of founding germ cells in humans" ppt
Ngày tải lên :
13/08/2014, 23:20
... 13 14 32 36 789 80 25300 21450 7320 188 0 15 580 486 0 2650 1450 310 Ratio Index ˆ a 19–30 years 31–35 years 36–40 years 41–45 years >45 years 104 5.1 2.1 4.7 0 .8 1.0 103 102 10 20 30 40 50 age Shown ... 0.090) and µ2 = 0.2 48/ year (0.204 – 0. 283 ) The 95% confidence intervals (95% CI) are based on Markov chain Monte Carlo methods [20] The expected number of oocytes (solid curve) and the pointwise 80 % ... cumulative rate function f(t) is defined as follows: µ1(t − 0.42), 0.42 ≤ t < 38 f (t ) = µ1( 38 − 0.42) + µ2 (t − 38) , 38 ≤ t < 52 (2) Conditional on the initial number X(t) = n of oocytes at...
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Báo cáo y học: "Enigma variations: control of sexual fate in nematode germ cells" docx
Ngày tải lên :
14/08/2014, 16:21
... tra-1 and tra-2 are conserved in C briggsae, and both regulate sexual development much as in C elegans [ 18, 19] A third gene, fog-3, is a major target of TRA-1 in C elegans [20] (see Figure 1), and ... spermatogenesis Given these findings, and the likelihood that C briggsae and C elegans had evolved self-fertile hermaphroditism independently, Hill et al [1] focused on the germline, and the role of the three ... between worms and flies 11 deposited research Third, what constitutes the switch that controls spermatogenesis and oogenesis in C briggsae? That C briggsae fem2(lf), fem-3(lf) and tra-1(lf) mutants...
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Interactions between early germ cells and inner germarial sheath cells in drosphila ovary
Ngày tải lên :
14/09/2015, 08:42
... (Cox et al., 19 98; Cox et al., 2000) and Yb (female sterile (1) Yb) and Hh (King and Lin, 1999; King et al., 2001), and pathways including Dpp signaling (Xie and Spradling, 19 98) , JAK-STAT (Janus ... Complex and its subunit 20 (Part II) 26 1.7 Function of Daughter of Sevenless in Drosophila (Par II) . 28 ii 1 .8 Objectives and Significance of This Thesis . 28 Chapter II Materials and ... signaling and Notch signaling (Arbouzova and Zeidler, 2006; King et al., 2001; Lopez-Onieva et al., 20 08; Song et al., 2007; Wang et al., 20 08; Ward et al., 2006; Xie and Spradling, 19 98) Dpp signaling...
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Tài liệu Báo cáo khoa học: Expression and secretion of interleukin-1b, tumour necrosis factor-a and interleukin-10 by hypoxia- and serum-deprivation-stimulated mesenchymal stem cells Implications for their paracrine roles ppt
Ngày tải lên :
18/02/2014, 04:20
... group FEBS Journal 277 (2010) 3 688 –36 98 ª 2010 The Authors Journal compilation ª 2010 FEBS 3 689 Paracrine anti-fibrotic effects of MSCs in vitro Z Li et al > 30 and < 30 kDa components using a ... ⁄ (ERK1 ⁄ 2) and p 38 mitogen-activated protein kinase (p 38) signalling pathways play important roles in hypoxia ⁄ SD-induced apoptosis of MSCs [20,21] and may also affect IL-1b and TNF-a transcriptional ... presence and absence of IL-10 *P < 0.05 and **P < 0.01 versus Cont group (D) Representative western blots for collagen I and III in the presence and absence of 0.1 lM angiotensin II and IL-10...
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Báo cáo Y học: A new siglec family member, siglec-10, is expressed in cells of the immune system and has signaling properties similar to CD33 docx
Ngày tải lên :
24/03/2014, 04:21
... D19S425 and D19S4 18, at a distance of 32 centiRay (cR) [log of odds (LOD) score ¼ 6.47] and 29 cR (LOD score ¼ 6. 28) , respectively, and corresponded to an approximate physical distance of 960 and 87 0 ... 34210 48; in pSPORT vector, Gibco/BRL, Grand Island, NY, USA) for several splice variants were obtained from Incyte and sequenced Sequencing and alignment Individual clone colonies were cultured and ... probabilities Genome Res 8, 86 –194 Gordon, D.C., Abajian, P & Green, P (19 98) Consed: a graphical tool for sequence finishing Genome Res 8, 195– 202 Smith, D.B & Johnson, K.S (1 988 ) Single-step purification...
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Báo cáo hóa học: "Inhibiting adenoid cystic carcinoma cells growth and metastasis by blocking the expression of ADAM 10 using RNA interference" pdf
Ngày tải lên :
18/06/2014, 16:20
... metastatic potential, and the changes in biological behaviors such as cell proliferation and metastasis were observed both in vitro and in vivo Materials and methods Cell lines and specimens Adenoid ... SACC -83 group (p < 0.001; Figure 2C, D, F) These results verified the difference in metastasis potential of SACC-LM and SACC -83 bothin vitro and in vivo Subsequently, both ADAM 10 mRNA and protein ... parental and mock-transfected SACC-LM cells were 0.57 ± 0.19 g and 0.60 ± 0.17 g, respectively, compared to 0.23 ± 0. 08 g, 0.21 ± 0.07 g, and 0.24 ± 0.07 g for the SACC-ADAM 10-RNAi (1), (2), and...
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