8 epidermal growth factor receptor

Tài liệu Báo cáo khoa học: Epidermal growth factor receptor in relation to tumor development: EGFR gene and cancer ppt

Ngày tải lên : 16/02/2014, 09:20

... the kinase domain of epidermal growth factor receptor Cell 125, 1137–1149 Voldborg BR, Damstrup L, Spang-Thomsen M & Poulsen HS (1997) Epidermal growth factor receptor (EGFR) and EGFR mutations, ... Mitsudomi T & Yatabe Y (2007) Mutations of the epidermal growth factor receptor gene and related genes as determinants of epidermal growth factor receptor tyrosine kinase inhibitors sensitivity in ... Sliwkowski MX (2006) Kinetic analysis of epidermal growth factor receptor somatic mutant proteins shows increased sensitivity to the epidermal growth factor receptor tyrosine kinase inhibitor, erlotinib...

8
684
0

Tài liệu Báo cáo khoa học: Epidermal growth factor receptor in relation to tumor development: EGFR-targeted anticancer therapy doc

Ngày tải lên : 16/02/2014, 09:20

... kinase inhibitors (TKIs) and triggered the development of this class of agents for targeting growth factor receptors frequently expressed in epithelial cancers [9] Two such inhibitors of the tyrosine ... EGFR-TKI resistance is key References Mendelsohn J & Baselga J (2003) Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer J Clin Oncol 21, 2787–2799 Lenz ... EGFR Cancer Treat Rev 35, 262–271 Peeters M, Price T & Van Laethem JL (2009) Antiepidermal growth factor receptor monotherapy in the treatment of metastatic colorectal cancer: where are we today?...

7
511
0

Tài liệu Báo cáo khoa học: Mitogen-activated protein kinase phosphatase-1 modulated JNK activation is critical for apoptosis induced by inhibitor of epidermal growth factor receptor-tyrosine kinase pdf

Ngày tải lên : 18/02/2014, 13:20

... (2002) Activation of BAD by therapeutic inhibition of epidermal growth factor receptor and transactivation by insulin-like growth factor receptor J Biol Chem 277, 27643–27650 10 Janmaat ML, Kruyt ... R & Bundred NJ (2001) ZD1839 (Iressa), a novel epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, potently inhibits the growth of EGFRpositive cancer cell lines with or without ... PL, Haserlat SM, Supko JG, Haluska FG et al (2004) Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to geﬁtinib N Engl J Med...

11
659
0

Báo cáo khoa học: Calmodulin-mediated regulation of the epidermal growth factor receptor doc

Ngày tải lên : 06/03/2014, 09:22

... the epidermal growth factor and nerve growth factor receptors J Biol Chem 271, 30505–30509 Browaeys-Poly E, Cailliau K & Vilain JP (1998) Fibroblast and epidermal growth factor receptor expression ... epidermal growth factor receptor ligands at a glance J Cell Physiol 218, 460–466 ´ 21 Villalobo A, Ruano MJ, Palomo-Jimenez PI, Li H & Martı´ n-Nieto J (2000) The epidermal growth factor receptor ... epidermal growth factor in epithelial LLC-PK1 cells Am J Physiol 265, C966–C975 29 Elliget KA, Phelps PC & Smith MW (1996) Transforming growth factor b modulation of the epidermal growth factor...

16
459
0

Báo cáo khoa học: Epidermal growth factor receptor-regulated miR-125a-5p – a metastatic inhibitor of lung cancer potx

Ngày tải lên : 07/03/2014, 00:20

... cancer cell lines correlates with dependence on the epidermal growth factor (EGF) receptor ⁄ extracellular signalregulated kinase ⁄ and EGF receptor ⁄ Akt pathway for proliferation Mol Cancer Ther ... epidermal growth factor receptor signaling and enhanced sensitivity to EGFR inhibitors in lung cancer Cancer Res 65, 226–235 Prenzel N, Fischer OM, Streit S, Hart S & Ullrich A (2001) The epidermal growth ... Studies leading to the identiﬁcation of ZD1839 (IRESSA): an orally active, selective epidermal growth factor receptor tyrosine kinase inhibitor targeted to the treatment of cancer Bioorg Med Chem Lett...

8
536
0

Báo cáo khoa học: Membrane distribution of epidermal growth factor receptors in cells expressing different gangliosides doc

Ngày tải lên : 16/03/2014, 16:20

... of growth factor receptors Nat Cell Biol 4, E75–E76 Wang, X.Q., Sun, P & Paller, A.S (2002) Ganglioside induces caveolin-1 redistribution and interaction with the epidermal growth factor receptor ... relatively weak interaction with membrane components Taking into account that growth factor receptors, including EGFr, and integrin receptors are functionally associated [27,28], we explored the behaviour ... with that of the total Ó FEBS 2004 EGF receptors distribution in cell membranes (Eur J Biochem 271) 2433 Fig Tyrosine-phosphorylated epidermal growth factor receptor (EGFr) membrane distribution...

10
327
0

Báo cáo khoa học: Phosphorylation of Hrs downstream of the epidermal growth factor receptor docx

Ngày tải lên : 17/03/2014, 11:20

... remains bound to the receptor at the acidic endosomal pH, thus activating the receptor kinase, transforming growth factor a (TGFa) rapidly dissociates and leaves the EGF receptor inactive after ... REFERENCES Schlessinger, J & Ullrich, A (1992) Growth factor signaling by receptor tyrosine kinases Neuron 9, 383–391 Komada, M & Kitamura, N (1995) Growth factor- induced tyrosine phosphorylation of ... 27 Ebner, R & Derynck, R (1991) Epidermal growth factor and transforming growth factor- alpha: diﬀerential intracellular routing and processing of ligand -receptor complexes Cell Regul 2, 599–612...

7
343
0

Báo cáo khoa học: Mutation of epidermal growth factor receptor is associated with MIG6 expression docx

Ngày tải lên : 30/03/2014, 01:20

... epidermal growth factor receptor signaling Mol Syst Biol 1, 2005.0010 Kholodenko BN (2007) Untangling the signalling wires Nat Cell Biol 9, 247–249 Santos SD, Verveer PJ & Bastiaens PI (2007) Growth factor- induced ... EGFR mutation and MIG6 expression T Nagashima et al Introduction Epidermal growth factor receptor (EGFR) is a membrane tyrosine kinase that is involved in the regulation of a wide ... Haluska FG et al (2004) Activating 5250 15 16 17 18 19 20 21 22 23 mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to geﬁtinib N Engl J Med...

13
347
0

Báo cáo hóa học: " Epidermal growth factor receptor gene copy number in 101 advanced colorectal cancer patients treated with chemotherapy plus cetuximab" doc

Ngày tải lên : 18/06/2014, 16:20

... implications of the ErbB/HER signaling network of growth factor receptors Adv Cancer Res 2000, 77:25-79 Diasio RB, Furie J: Targeting the epidermal growth factor receptor in the treatment of colorectal ... epidermal growth factor receptor by immunohistochemestry J Clin Oncol 2005, 23(9):1803-1811 Moroni M, veronese S, Benvenuti S, et al.: Gene copy number for epidermal growth factor receptor and ... 23 24 Prewett M, Hooper A, Bassi R, et al.: Enanched antitumor activity of antiepidermal growth factor receptor monoclonal antibody IMC-C225 in combination with irinotecan (CPT-11) against human...

8
472
0

Báo cáo khoa học: " Assessment of Epidermal Growth Factor Receptor (EGFR) expression in human meningioma" docx

Ngày tải lên : 09/08/2014, 09:20

... of epidermal growth factor receptors in meningiomas J Neurosurg 1997, 87(2):315-323 Diedrich U, Lucius J, Baron E, Behnke J, Pabst B, Zoll B: Distribution of epidermal growth factor receptor gene ... Macchia V: Epidermal growth factor receptor in human brain tumors J Endocrinol Invest 1992, 15(1):31-37 Johnson MD, Horiba M, Winnier AR, Artiaga CL: The epidermal growth factor receptor is associated ... Gregoriou M, Hughes JT: Epidermal Growth Factor Receptor expression in 72 meningiomas Cancer 1990, 66(1):152-155 Dorward NL, Hawkins RA, Whittle IR: Epidermal growth factor receptor activity and clinical...

7
302
0

Báo cáo khoa học: " The epidermal growth factor receptor (EGFR) in head and neck cancer: its role and treatment implications" pptx

Ngày tải lên : 09/08/2014, 10:20

... association with epidermal growth factor receptor/ transforming growth factor alpha expression in head and neck squamous carcinoma and inhibition by anti-epidermal growth factor receptor treatments Cancer ... head and neck 10 RT: radiation therapy EGF: epidermal growth factor EGFR: epidermal growth factor receptor 11 TGF-α: transforming growth factor alpha 12 RTOG: Radiation Therapy Oncology Group ... analysis of epidermal growth factor action: assignment of human epidermal growth factor receptor gene to chromosome Proc Natl Acad Sci 1980, 77:4188-4192 Roskoski R Jr: The ErbB/HER receptor protein-tyrosine...

6
295
0

Rapid detection of epidermal growth factor receptor mutations with multiplex PCR and primer extension in lung cancer pdf

Ngày tải lên : 10/08/2014, 05:21

... M, Bunn PA Jr, Di Maria MV, Veve R, Bremmes RM, Baron AE, Zeng C, Franklin WA: Epidermal growth factor receptor in nonsmall-cell lung carcinomas: correlation between gene copy number and protein ... Fujiuchi S, Nishigaki Y, Ishida S, Nagase A, Miyokawa N, Hirata S, Kikuchi K: Epidermal growth factor receptor expression correlates with poor prognosis in non-small cell lung cancer patients ... Oncol Rep 2000, 7(3):603-607 Veale D, Ashcroft T, Marsh C, Gibson GJ, Harris AL: Epidermal growth factor receptors in non-small cell lung cancer Br J Cancer 1987, 55(5):513-516 Miller VA, Kris MG,...

6
234
0

Báo cáo y học: "Wildtype epidermal growth factor receptor (Egfr) is not required for daily locomotor or masking behavior in mice" pps

Ngày tải lên : 10/08/2014, 09:20

... transforming growth factor- alpha and neuregulin-1 suppress active behaviors and cause weight loss in hamsters Brain Research 2005, 1038:171-182 Wakefield LM, Yang Y, Dukhanina O: Transforming growth factor- beta ... JA, Chetty R, Burgess AW, Dunn AR: A mutation in the epidermal growth factor receptor in waved-2 mice has a profound effect on the receptor biochemistry that results in impaired lactation Proceedings ... KE, Amann V, Threadgill DW: Phenotypic variation resulting from a deficiency of epidermal growth factor receptor in mice is caused by extensive genetic heterogeneity that can be genetically and...

5
323
0

báo cáo khoa học: "Sustained complete remission of human epidermal growth factor receptor 2-positive metastatic breast cancer in the liver during long-term trastuzumab (Herceptin) maintenance therapy in a woman: a case report" docx

Ngày tải lên : 11/08/2014, 02:22

... Editor-in-Chief of this journal Abbreviations CT: computed tomography; HER2: human epidermal growth factor receptor 2; MBC: metastatic breast cancer Authors’ contributions JS collected and analyzed ... efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic Syrios et al Journal of Medical Case Reports 2010, 4:401 http://www.jmedicalcasereports.com/content/4/1/401 ... doi:10.1186/1752-1947-4-401 Cite this article as: Syrios et al.: Sustained complete remission of human epidermal growth factor receptor 2-positive metastatic breast cancer in the liver during long-term trastuzumab (Herceptin)...

4
211
0

Báo cáo y học: "Role of epidermal growth factor receptor activation in regulating mucin synthesis" pdf

Ngày tải lên : 12/08/2014, 18:20

... Nasuhara Y, Sato A, Takahashi T, Homma Y, Kawakami Y: Expression of epidermal growth factor and epidermal growth factor receptor immunoreactivity in the asthmatic human airway Am J Respir Crit Care ... epidermal growth factor receptors to airway goblet cell production Am J Respir Crit Care Med 2001, 163:1–6 Elovic A, Wong DTW, Weller PF, Matossian K, Galli SJ: Expresα sion of transforming growth factors-α ... process in goblet-cell development [4] Stimuli for mucin synthesis: role of the epidermal growth factor receptor cascade The mechanism of EGFR expression and activation Stimulation of airway epithelial...

5
375
0

Báo cáo y học: "Systems analysis of circadian time-dependent neuronal epidermal growth factor receptor signaling" pdf

Ngày tải lên : 14/08/2014, 16:21

... of epidermal growth factor receptor changes in the hypothalamus during the onset of female puberty Mol Cell Neurosci 1994, 5:246-262 Li X, Sankrithi N, Davis FC: Transforming growth factor- alpha ... of short term signaling by the epidermal growth factor receptor J Biol Chem 1999, 274:30169-30181 Terlau H, Seifert W: Influence of epidermal growth factor on long-term potentiation in the hippocampal ... Maity A, Pore N, Lee J, Solomon D, O'Rourke DM: Epidermal growth factor receptor transcriptionally up-regulates vascular endothelial growth factor expression in human glioblastoma cells via a pathway...

15
312
0

Báo cáo sinh học: "Silencing the epidermal growth factor receptor gene with RNAi may be developed as a potential therapy for non small cell lung cancer" pot

Ngày tải lên : 14/08/2014, 19:22

... epidermal growth factor receptor inhibition by ZD1839 (Iressa) Cancer Res 2002, 62:4300-4306 Williams KJ, Telfer BA, Stratford IJ, et al.: ZD1839 ('Iressa'), a specific oral epidermal growth factor receptor- tyrosine ... R, Blanco R, et al.: Inhibition of growth factor production and angiogenesis in human cancer cells by ZD1839 (Iressa), a selective epidermal growth factor receptor tyrosine kinase inhibitor Clin ... of human malignancies by epidermal growth factor Br J Cancer 1995, 72:615-619 Zhang M, Zhang X, Bai CX, Chen J, Wei MQ: Inhibition of epidermal growth factor receptor (EGFR) by RNA interference...

12
314
0

Quantification of epidermal growth factor receptor dynamics and interactions in living cells by fluorescent correlation and cross correlation spectroscopy

Ngày tải lên : 10/09/2015, 09:25

... polypeptide, now known as epidermal growth factor (EGF) (Cohen 1962) In 1975, the same group characterized its cell membrane receptor, namely epidermal growth factor receptor (EGFR) (Carpenter, Lembach ... second D Diffusion coefficient DNA Deoxyribonucleic acid EGFR Epidermal growth factor receptor EGF Epidermal growth factor FCCS Fluorescence cross-correlation spectroscopy FCS Fluorescence correlation ... cross-correlation spectroscopy (R)TK (Receptor) Tyrosine kinase 𝑉 𝑒𝑓𝑓 TM Transmembrane Effective volume xiv Chapter Introduction 1.1 Epidermal Growth Factor Receptor (EGFR) The history of studying...

186
1.4K
0

Báo cáo Y học: Chimeric receptor analyses of the interactions of the ectodomains of ErbB-1 with epidermal growth factor and of those of ErbB-4 with neuregulin potx

Ngày tải lên : 24/03/2014, 03:21

... (1993) A 40-kDa epidermal growth factor/ transforming growth factor a-binding domain produced by limited proteolysis of the extracellular domain of the epidermal growth factor receptor J Biol Chem ... position 13 of human growth factor in receptor binding J Biol Chem 268, 10114–10119 26 Campion, S.R & Niyogi, S.K (1994) Interaction of epidermal growth factor with its receptor Prog Nucleic ... epidermal growth factor receptor J Biochem 127, 65–72 30 Abe, Y., Odaka, M., Inagaki, F., Lax, I., Schlessinger, J & Kohda, D (1998) Disulﬁde bond structure of human epidermal growth factor receptor...

7
450
0

Tài liệu Báo cáo khoa học: The ubiquitin ligase Itch mediates the antiapoptotic activity of epidermal growth factor by promoting the ubiquitylation and degradation of the truncated C-terminal portion of Bid ppt

Ngày tải lên : 16/02/2014, 09:20

... of epidermal growth factor family in the regulation of postnatal somatic growth Endocr Rev 28, 284–296 Henson ES & Gibson SB (2006) Surviving cell death through epidermal growth factor (EGF) ... BA & Angers A (2009) Reciprocal regulation of the ubiquitin ligase Itch and the epidermal growth factor receptor signaling Cell Signal 21, 1326–1336 Gao M, Labuda T, Xia Y, Gallagher E, Fang D, ... Henson ES, Haney N, Villanueva J & Gibson SB (2002) Epidermal growth factor protects epithelial-derived cells from tumor necrosis factor- related apoptosis-inducing ligand-induced apoptosis by...

12
718
0