7 early and late cognitive dysfunction may result from different etiologies
Báo cáo sinh học: "Association between neuroserpin and molecular markers of brain damage in patients with acute ischemic stroke" pot
Ngày tải lên :
18/06/2014, 19:20
... and designed the research; analyzed and interpreted the data; performed statistical analysis, handled funding and supervision and drafted the manuscript RRG, DB, OM, have acquired, analyzed and ... out on admission and between days and Infarct volume was calculated in the second CT by using the formula 0.5 × a × b × c, where a and b are the largest perpendicular diameters, and c is the number ... patients’ clinical and laboratory results Laboratory determinations Serum glucose, platelet count and coagulation tests were assessed in a central laboratory Blood samples, drawn from all patients...
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báo cáo hóa học:" Association between neuroserpin and molecular markers of brain damage in patients with acute ischemic stroke" pdf
Ngày tải lên :
20/06/2014, 03:20
... and designed the research; analyzed and interpreted the data; performed statistical analysis, handled funding and supervision and drafted the manuscript RRG, DB, OM, have acquired, analyzed and ... out on admission and between days and Infarct volume was calculated in the second CT by using the formula 0.5 × a × b × c, where a and b are the largest perpendicular diameters, and c is the number ... patients’ clinical and laboratory results Laboratory determinations Serum glucose, platelet count and coagulation tests were assessed in a central laboratory Blood samples, drawn from all patients...
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Báo cáo khoa học: "Biological markers of lung injury before and after the institution of positive pressure ventilation in patients with acute lung injury" potx
Ngày tải lên :
13/08/2014, 03:20
... contributions GC and MAM designed the study GC performed data acquisition GC and SB performed the immunoassays MC and MAM performed the data analysis and interpretation and drafted the manuscript MC and AS ... IL-8, vWF, and ICAM-1 IL-8 and IL-6 are pro-inflammatory cytokines that are elevated in patients with ALI and are predictive of clinical outcomes, and their levels are altered by different ventilation ... 6.5) and lung-protective (7.6 ml/kg, PEEP 14.8) ventilation strategies and measured bronchoalveolar lavage (BAL) and plasma biomarker levels at baseline and at 36 hours after intubation BAL and...
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Textbook of Traumatic Brain Injury - part 4 pdf
Ngày tải lên :
10/08/2014, 18:20
... of other anxiety disorders Mayou and Bryant (1994) and Mayou et al (1993) evaluated 188 people soon after a motor vehicle accident, then months later, and then year later Patients were interviewed ... condition May appear stunned or dazed May appear drowsy or indifferent May be disoriented or have trouble with complex commands May complain of headache or nausea or vomit a See Teasdale and Jennett ... the anxiety, and the situation in which the anxiety occurs Other cognitive or somatic complaints may mask the anxiety symptoms Therefore, collateral information from family members and others involved...
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Báo cáo y học: "Technical Considerations in Decompressive Craniectomy in the Treatment of Traumatic Brain Injury"
Ngày tải lên :
25/10/2012, 11:40
... procedure may lead to temporal lobe herniation and necrosis.18 A study performed by Alexander et al demonstrated that the calculated additional space provided by subtemporal decompression ranged from ... refractory intracranial hypertension, and the variations in results between studies may be explained by the different methods of surgical decompression Presently, unilateral fronto-temporoparietal craniectomy/hemisphere ... the dura and to allow it to stretch and expand They performed decompressive craniectomy combined with this technical improvehttp://www.medsci.org Int J Med Sci 2010, ment in six patients, and found...
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awareness of deficit after brain injury clinical and theoretical issues jan 1991
Ngày tải lên :
11/06/2014, 09:45
... 1889 and "emphasized the relationship of unawareness of disease and focal cerebral lesions" (Friedland and Weinstein, 1977) Anton was making the point that a lack of awareness could result from ... published 1900) Friedland, R P., and Weinstein, E A (1977) Hemi-inattention and hemisphere specialization: Introduction and historical review In E A Weinstein and Friedland R P (eds.), Advances ... beliefs may be viewed differently by the cognitive biologist and the logician More precisely, they show that certain (wholly irrational) beliefs, rather than being inferred from other beliefs, may...
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Báo cáo hóa học: " Effectiveness of a Wii balance board-based system (eBaViR) for balance rehabilitation: a pilot randomized clinical trial in patients with acquired brain injury" ppt
Ngày tải lên :
19/06/2014, 08:20
... the scores of scales and tests The results are given in terms of mean ( X ) and standard deviation (s) The subindexes and 20 represent the ¯ assessments carried out before and after the treatment, ... due to causes unrelated to the study and system, and, consequently, their data are not included in the present contribution The final sample consisted of 11 men and women ranging from 16 to 76 years ... throughout the sessions and a different reinforcement when the patient performs an incorrect action The patient’s score is continuously displayed and points are accumulated to calculate the final score...
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báo cáo hóa học: "Usability of a virtual reality environment simulating an automated teller machine for assessing and training persons with acquired brain injury" pdf
Ngày tải lên :
19/06/2014, 08:20
... formulated concepts and ideas in Part I of the study WAKY and YEWH collected and analyzed data for Part I KNKF formulated concepts in Part II of the study CBCH, LKCK, LJCK, and LTHY collected and ... difficulties understanding the operational tasks, and 6) the influence of social pressure In addition, persons with acquired brain injuries (ABI) have different levels of cognitive function that ... self-care and participate in the community [3] They may also lack the ability to operate an ATM either because of cognitive deficits like memory difficulty, poor problem-solving, or slow motor and...
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báo cáo hóa học: " Inhibition of the alternative complement activation pathway in traumatic brain injury by a monoclonal anti-factor B antibody: a randomized placebo-controlled study in mice" pot
Ngày tải lên :
19/06/2014, 22:20
... Sunnyvale, CA) All samples were analyzed in duplicate and results were calculated from the means of duplicate sample analysis The standard curve was linear from 0.1 ng/ml to 50 ng/ml 100 × ( sample mean ... MET, and MR performed the TUNEL and immunohistochemistry experiments IL, MR and DH performed the real-time RT-PCR analyses DR and PAW performed the murine C5a ELISA experiments All authors read and ... Germany) RNA was isolated and further purified using RNeasy® Mini-kits (Qiagen) and RNA concentrations were measured using a spectrophotometer (Bio-Rad, Munich, Germany) From each brain hemisphere,...
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báo cáo hóa học: " Air pollution & the brain: Subchronic diesel exhaust exposure causes neuroinflammation and elevates early markers of neurodegenerative disease" pdf
Ngày tải lên :
19/06/2014, 22:20
... system Band density was quantitated with ImageJ [34] and analyzed as a ratio of GAPDH and a synuclein Results are reported as a percent increase from control TNFa, IL-6, MIP-1a, IL-1b, Ab42, and ... elevates subclinical markers and induces AD-like pathology in both the frontal and temporal lobe Figure Subchronic DE Exposure Differentially Regulates Other Cytokines and Chemokines in the Midbrain ... component of plaques, and has been widely implicated in AD and frontotemporal dementia (FTD) pathology [43] In fact, deposition of Ab42 is linked to cognitive changes and may even be a marker...
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báo cáo hóa học: " Differential aquaporin 4 expression during edema build-up and resolution phases of brain inflammation" doc
Ngày tải lên :
19/06/2014, 22:20
... peak at dpi and a secondary decrease between and dpi (p = 0.015) The ADC values at 7, 14 and 20 dpi returned to baseline and were not statistically different from those of the contralateral side ... lesion site (3 and dpi, arrows) followed by a complete restoration of the BBB integrity at the later time points (14 and 20 dpi) (B) and (C) are representative illustrations of MRI and histological ... Double labeling of ED1 (Alexa 488, green) and Iba1 (CY3, red) in the contralateral brain (A) and at the lesion site at dpi (B) and 14 dpi (C) On the contralateral side (A), only resting microglia...
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báo cáo hóa học: " Origin and consequences of brain Toll-like receptor 4 pathway stimulation in an experimental model of depression" docx
Ngày tải lên :
19/06/2014, 22:20
... BEHAVIOR in IL-1b and COX-2/PGE2 in brain cortex This result supports the notion that LPS from translocated bacteria stimulates TLR-4, and in that way produces the increases in IL-1b and COX-2/PGE2 ... data and revising the manuscript critically; LB and EB contributed to acquisition, analysis and interpretation of CMS model and behavioural data; JAM and JRC revised the manuscript critically; and ... group values) for pro-inflammatory and oxidative/nitrosative parameters previously analyzed, including LPS and LBP plasma concentrations and TLR4 and MD-2 expression and mRNA levels In this vein,...
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báo cáo hóa học: " Interleukin-1alpha expression precedes IL-1beta after ischemic brain injury and is localised to areas of focal neuronal loss and penumbral tissues" pdf
Ngày tải lên :
19/06/2014, 22:20
... Nuclear fluorescence intensities for IL-1α and GFP were quantified from confocal images, and the fold enrichment of IL-1α and GFP in microglial nuclei was calculated in comparison to whole cell fluorescence ... blood brain barrier (BBB) and its presence in the brain parenchyma indicates BBB disruption and injury [9] Staining of coronal brain sections from C57BL6/H mice (Figure 2C) and CX3CR1-GFP+/- mice ... localization between the nucleus and cytosol was regulated (Figure 2F) We have previously reported that IL-1α is retained in the nuclei of dead and dying cells [11], and also that microglia die in...
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Báo cáo y học: "Plasmatic B-Type Natriuretic Peptide and C-Reactive Protein in Hyperacute Stroke as Markers of Ct-Evidence of Brain Edema." pptx
Ngày tải lên :
08/08/2014, 16:23
... with edema (from 130/75 to 160/92; from 155/85 to 170/95; and from 165/90 to 188/100); in the remainder it was similar as at baseline The mean NIHSS score on admission was 7.5 (SD: 6.18) and at discharge ... hyponatremia and natriuresis in subarachnoid hemorrhage [26] as well as to hyponatremia and delayed vasospasm-related ischemic deficits [27] Focal brain edema was related with elevations of ANP and BNP ... peptides and mortality after stroke Stroke 2005; 36: 1016-1020 14 Etgen T, Baum H, Sander K, Sander D Cardiac troponins and N-terminal pro-brain natriuretic peptide in acute ischemic stroke not relate...
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Theory of Brain Function quantum mechanics and superstrings - part 4 ppt
Ngày tải lên :
10/08/2014, 00:21
... α-helix, 31% β-sheet and 29% random coil The α-tubulin consists of four α-helixes, four β-sheets, and two random coils, while the β-tubulin has six α-helixes, one β-sheet, and seven random coils Each ... each and every turn! The alert reader may have already noticed the stunning similarity between the string dynamics in singular spacetime backgrounds, like black holes and spacetime foam, and the ... made of up (u) and down (d) constituent quarks, but for my arguments they are of comparable mass and thus would give the same results Now, since the bulk of matter is due to nucleons, and not to...
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Traumatic brain injury and the effects of diazepam, diltiazem, and MK-801 on GABA-A receptor subunit expression in rat hippocampus ppt
Ngày tải lên :
10/08/2014, 05:21
... [25] The β subunits also differentially regulate inhibitory Cl- flow [35] The transitory increase in β3 expression at hours and decrease at and 24 hours post-injury may be related to time-dependent ... relevance, often through the use of knockout and knockdown animals Differential changes in subunits may have important relevance since GABAAR subunits regulate different functions The β subunit of the ... by glutamate-related excitotoxic effects of TBI Specifically, Stelzer and Shi [17] found that NMDA and glutamate altered GABAAR currents in acutely isolated hippocampal cells, and this effect...
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Báo cáo y học: "Regional characterization of energy metabolism in the brain of normal and MPTP-intoxicated mice using new markers of glucose and phosphate transport" doc
Ngày tải lên :
10/08/2014, 05:21
... EL and HA: carried out the immunofluorescence assays and drafted the manuscript; JLB and MS: conceived the envelope-derived tagged ligands while; JLB, HA, ML and JT: generated, optimized and ... ligand, we observed a staining of GLUT1 in the corpus callosum and the basal ganglia apparently weaker than in the cerebellum and in the cortex These results were reproducible in all animals and ... Thus, assessing Pi metabolism with ligands to the PiT1 and PiT2 high affinity transporters may be a more reliable approach, although PiT1 and PiT2 might exhibit different cellular functions [12]...
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Textbook of Traumatic Brain Injury - part 1 ppt
Ngày tải lên :
10/08/2014, 18:20
... findings from 13 studies Source Bassett and Slater 1990; Bawden et al 1985; Costeff et al 1988; Dennis and Barnes 1990; Ewing-Cobbs et al 1985, 1987; Gulbrandson 1984; Hannay and Levin 1988; Jordan and ... studies (Bassett and Slater 1990; Bawden et al 1985; Costeff et al 1988; Dennis and Barnes 1990; Ewing-Cobbs et al 1985, 1987; Gulbrandson 1984; Hannay and Levin 1988; Jordan and Murdoch 1990; ... findings from NHIS, NHAMCS, and NHDS vary widely (see Figure 1–1) because the data sources are so different from one another An estimate derived from published sources (summarized in Figure 1–3 and...
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Textbook of Traumatic Brain Injury - part 2 potx
Ngày tải lên :
10/08/2014, 18:20
... phases of recovery; and results of neuroimaging, electrophysiological, and neuropsychological testing delineating the location and extent of injury and pattern of cognitive and memory impairment ... apathy, depressed mood, and anxiety (Hinkeldey and Corrigan 1990; Thomsen 1984; Van Zomeren and Van Den Burg 1985) Signs and Symptoms After TBI The types of signs and symptoms that may occur after a ... disturbance, and hypersexuality (Cummings 1985; Gualtieri 1991) Some of the signs and symptoms of TBI result from the patient’s emotional and psychological responses to having experienced a TBI and having...
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