7 recovering after the nologging clause is specified

... database This protection mode (the default) provides the highest level of data protection that is possible without affecting the performance of the primary database This is accomplished by allowing ... the primary database on a block-for-block basis The database schema, including indexes, are the same A physical standby database is kept synchronized with the primary database by recovering the ... The transition occurs without having to re-create either database A failover is when the primary database is unavailable Failover is performed only in the event of a catastrophic failure of the...

Ngày tải lên: 17/01/2014, 06:20

... adaptation [23,24], the use of aids [25-27], assistance from others [28,29] and changes in perception [30,31] The aim of this prospective analysis was to describe the onset and persistence of person-perceived ... of the natural history of these three levels and of the underlying health conditions, is uneven The prevalence and incidence of several health conditions and impairments (e.g cardiovascular disease ... outcomes The following analysis was carried out on the observed data, i.e on those completing the 3-year follow-up, and to assess the effects of loss to follow-up, we repeated the onset and persistence...

Ngày tải lên: 18/06/2014, 19:20

... forestlands vis-à-vis the squared products had an upward trend, and such a trend increased several times in comparison with the early years of the studied period The data collected from the total ... during the last 20 years MATERIALS AND METHODS Areas under Study Located in the northern part of Iran, the study areas are known as the Northern Forests or Hyrcanian Forests and are distributed ... comparison with the years between 1989 and 1999 The total log volume imported to Iran since 1989 has been less than 1% in total This information, together with other references, showed that other...

Ngày tải lên: 07/08/2014, 10:21

... the position Q120 is most likely responsible for the observed effects The interpretation of the low-affinity Km values (not given) is not straightforward since the explanation for this phase is ... for docking The figure was prepared on the basis of the published coordinates (pdb1ar1), using the SWISS PDB VIEWER/POV RAY program [31] Here we give a comprehensive description of the interaction ... assignment to either a hyperbolic or nonhyperbolic Michaelis–Menten kinetic regime Tables and list the relevant parameters, Km and kcat, for the different ionic strength conditions: the Km value is taken...

Ngày tải lên: 22/02/2014, 07:20

... for the wildtype enzyme, Glu144 is the only relevant titratable residue in the pH 6–12 range and the pKa of this residue is affected by substratebinding Therefore, it is surprising that the pH-kcat ... where the enzyme is most active Summarizing, the calculations show that the carboxylic groups in the Asp140-Asp142-Glu144 triad contain two protons at the pH where the enzyme is most active The ... raising it by 3.8 to 5.4 units, depending on the position of Asp142 and the calculation used Interestingly, the calculations also suggest that the magnitude of this effect is in part due to the...

Ngày tải lên: 07/03/2014, 14:20

... to locate the catalytic center and predict the shape of the dimeric protein The model reinforced our hypothesis proposed above To further address this hypothesis, we have characterized the protein ... of the HDC reactions with the natural substrate histidine and the histidineanalogs HisOMe and a-FMH This scheme was built from the major forms for each step mentioned in the text deduced from the ... before, this external aldimine complex (complex III) is the final product of the reaction with HisOMe In fact, after min, the spectra of the HisOMe-treated samples had stabilized with the 390-nm...

Ngày tải lên: 08/03/2014, 08:20

... on the b4-strand (Fig 1) The Glu (E) in this motif acts as the catalytic proton donor, and the second Asp (D2) is supposed to contribute to the stabilization of the essential distortion of the ... that these residues stabilize the distortion of the NAG3 residue In these interactions, we particularly focused on the Trp664 residue, which is located at the bottom of the active site cleft The ... could be formed with the assistance of an amino acid residue other than the DXDXE motif, as originally proposed by Tews et al [43] This is simpler than the mechanism of the other family 18 chitinases...

Ngày tải lên: 15/03/2014, 11:20

... biosynthesis and molybdopterin biosynthesis, respectively, and for the sulfuration of uridine in tRNA to thiouridine can be envisaged [34–36] This mechanism probably also applies for the synthesis ... MCRs isolated from the Black Sea mats a ANME-1 cluster (Table 2) The sequence around the methylated histidine is shown in Fig The methylated arginine (R271) is also highly conserved in the a-subunit ... electron transport from the disulfide anion radical to the nickel The redox potential of the thioxo peptide ⁄ radical couple is estimated to lie between that of the disulfide ⁄ disulfide anion radical...

Ngày tải lên: 16/03/2014, 05:20

... coli The inserts of the selected neosynthetized vectors were fully sequenced As neosynthetized DNA is not a template for the reaction, the amplification is linear, which is expected to keep the ... side-chain with the aromatic ring of the substrate Our model supports this hypothesis The model predicts that I371 is another residue in close proximity to the substrate I371 aligns with F361 in the limonene ... that of P1 The K484M mutation does not significantly affect the P2/P1 ratio This is not surprising considering that it does not affect the global rate of I2C metabolism As the length of the I2C molecule...

Ngày tải lên: 17/03/2014, 10:20

... DAAO, the spectrum of the oxidized enzyme was converted into the reduced form, lacking the isosbestic points and peak maxima characteristic of the formation of the semiquinone intermediate The ... acid/base catalysis, e.g in the subtraction of the a-carbon proton The most striking difference observed for the Y238 mutants in comparison to the wild-type DAAO is a decrease in the turnover number ... [28] Furthermore, though these substitutions modied the interaction of the reduced enzyme with the IP product, as indicated by the observation that Y228F totally abolished the formation of the absorbance...

Ngày tải lên: 17/03/2014, 17:20

... Learning the Basics of LIS Flexible Analyses 6–2 What Is Flexible Analysis? 6–2 How Is Flexible Analysis Different From Standard Analysis? 6–2 How Is LIS Flexible Analysis ... What Is the Administrator Workbench? 7–5 What Is the Meta Data Repository? 7–5 What Is the Staging Engine? 7–5 What Is an InfoCube? 7–6 What Is the ... A–2 What Is The ABAP List Viewer? A–2 ABAP List Viewer: Cost Versus Benefit Analysis A–3 Report Lists Without ABAP List Viewer A–4 Report Lists With ABAP List Viewer...

Ngày tải lên: 27/10/2013, 07:15

... university, it is best to use a formal, impersonal style… 11 Some clothes can be made from synthetic… 12 Inside the hydrogen atom, there is one electron… a …otherwise the conclusions they come to ... the sentence Choose the best ending for each of the sentence extracts below from the list underneath: 10 11 12 13 The decision to expand the airport has caused a great deal of controversy,… The ... night to finish their work, but it is impossible to maintain this for very long and so it is not recommended _ One of the main causes of the increase in inner-city lawlessness is the number...

Ngày tải lên: 02/11/2013, 10:20

... through the bi-directional relationship between individuals In one direction, there is trust from the employee to his manager and there is also trust from the manager to the employee Therefore, ... judgment is made which determines the importance of the transaction which is then factored into the totality of all other transactions in order to determine the value of the judgment Trust becomes the ... transaction If the interaction outcome is negative, the trust relationship is diminished proportional to the scale of the violation The value or weight of each transaction is compared to the outcomes...

Ngày tải lên: 24/12/2013, 18:15

... of Drug Distribution Following its uptake into the body, the drug is distributed in the blood (1) and through it to the various tissues of the body Distribution may be restricted to the extracellular ... license 24 Distribution in the Body Blood-Tissue Barriers Drugs are transported in the blood to different tissues of the body In order to reach their sites of action, they must leave the bloodstream ... confined to the vascular space, because their permeation through the blood-tissue barrier, or endothelium, is impeded, even where capillaries are fenestrated This property is exploited therapeutically...

Ngày tải lên: 22/01/2014, 00:20

... within the context of the full-length PAI-2 3¢ UTR, and the influence of these mutations on the mRNA decay characteristics was determined As shown in Fig 5, the estimated half-lives of these transcripts ... protein binding activity to the ‘extended ARE’, despite the fact that it contributes to mRNA stability Whether this is a consequence of the limitation of the REMSA approach or the influence of alternative ... manner with the nonameric ARE To determine whether the ‘extended ARE’ possessed all of the destabilizing elements within the PAI-2 3¢ UTR, the entire 108 nucleotide sequence was deleted from the 3¢...

Ngày tải lên: 16/02/2014, 09:20

... glial scar formation It is important to note that the synthesis of MT1 and MT2 in the injured or diseased brain is quite different from the synthesis of GIF While GIF synthesis is generally considered ... injured brain, however, the synthesis of MT1 and MT2, as well as the synthesis of GIF, are up-regulated by reactive astrocytes in the vicinity of the lesion [23] This suggests that these proteins may ... processes of these cells Astrocytic synthesis of GIF is mainly found in the cortex, brainstem and spinal cord [6] Additionally however, there are also consistent reports of neuronal synthesis of GIF,...

Ngày tải lên: 16/02/2014, 15:20

... 65% activity after h We then applied the technique of N-terminal pegylation to visualize the relative solvent exposure of the N-terminus of FVIIa To the best of our knowledge, this is the rst time ... cleavage of the scissile bond This would affect FX and peptide hydrolysis similarly, supported by the similar decrease in the rate of cleavage of both types of substrates The effect of the G372(223)A ... orientation of the P1 Arg residue The magnitude of the effects of the G372(223)A mutation is slightly substrate-dependent The fact that the relative reduction in activity was not greater in the presence...

Ngày tải lên: 18/02/2014, 08:20

... analysis, and the determination of released ammonia The coupled enzyme assay revealed the mechanism of the deamination reaction and the subsequent metabolism, including the deamination step The ... accumulated via these steps based on the changes in the absorption spectrum (Fig 2B,C) In addition, picolinic acid was not detected in the reaction mixture after the coupled enzyme assay The other possibility ... succinate/glucose-grown cells; therefore, the synthesis of the enzyme was inducible Table shows a summary of a typical enzyme purification The enzyme was purified 103-fold with an overall yield of 2% The specific...

Ngày tải lên: 19/02/2014, 16:20

... mutant GAPDH In all plots, the arrow on the left indicates the beginning of the association phase; the beginning of the dissociation phase is marked by the arrow on the right The experimental data ... code in PDB:1JN0), the other being the catalytic domain (residues 148313) The latter comprises the S loop (residues 177203) that is close to the NADP nicotinamide moiety [35] The structure of wild-type ... In the past [24], we have shown that the conserved residue arginine 64 of C reinhardtii PRK is involved in the interaction of this enzyme with the GAPDHCP12 subcomplex This report describes the...

Ngày tải lên: 19/02/2014, 16:20