6immunogenicity and efficacy of mucosal dry powder vaccines

... compliance Compliance was assessed by capsule count at visits 3, 4, and and review of subject diary Efficacy and Safety Variables Efficacy and safety measurements assessed Adverse events During the study, ... Canada) Appropriateness of Measurements The efficacy and safety assessments used in this study were standard for OA and are widely used and recognized as reliable, accurate, and relevant WOMAC scores ... common form of arthritis, and it is often associated with significant disability and an impaired quality of life Clinical and radiographic surveys have found that the prevalence of OA increases...

Ngày tải lên: 26/10/2012, 09:48

... transfected with μg of the FLC, 0.8 μg each of the N and P, and 0.1 μg of the L support plasmids in a volume of 100 μl of Opti-MEM per well Transfection was carried out with Lipofectamine 2000 (Invitrogen, ... (A) and LRT (B) of AGMs rHPIV1 wt and non-ts rHPIV1 mutants were assigned a shut-off temperature of 40°C for the purposes of this schematic The limit of detection for the mean sum of daily virus ... transfected with μg each of the FLC and the pCL-Neo-BCI-T7 plasmid (expressing T7 polymerase under the control of a eukaryotic promoter) [30], 0.2 μg each of the N and P, and 0.1 μg of the L support...

Ngày tải lên: 18/06/2014, 18:20

... transfected with μg of the FLC, 0.8 μg each of the N and P, and 0.1 μg of the L support plasmids in a volume of 100 μl of Opti-MEM per well Transfection was carried out with Lipofectamine 2000 (Invitrogen, ... (A) and LRT (B) of AGMs rHPIV1 wt and non-ts rHPIV1 mutants were assigned a shut-off temperature of 40°C for the purposes of this schematic The limit of detection for the mean sum of daily virus ... transfected with μg each of the FLC and the pCL-Neo-BCI-T7 plasmid (expressing T7 polymerase under the control of a eukaryotic promoter) [30], 0.2 μg each of the N and P, and 0.1 μg of the L support...

Ngày tải lên: 20/06/2014, 01:20

... contrast to self-expanding stainless steel biliary wall stents and other nitinol stents [4,9-11], none of the nitinol expandable stents were broken, shortened or migrated The flared ends of the stent ... likely prevented stent migration and increased stent stability Dorsoventral radiographs comparing the length and location of each stent with the number of cervical and thoracic vertebrae showed ... implantation of only one stent for treatment of tracheal collapse, whereas dogs required multiple implantations of other nitinol stents [4,9,11] In conclusion, we found that implantation of self- expandable...

Ngày tải lên: 07/08/2014, 20:23

... degrees of success ranging from a maximum of 61-71% to an average of 23% Side-effects include osteoradionecrosis of the temporal bone, radiation necrosis of the temporal lobe, mastoiditis and second ... dysphagia The presence of jugular foramen syndrome (paresis of cranial nerves IX-XI) is pathognomonic of this tumor, but it usually follows the initial symptoms of hearing loss and pulsatile tinnitus ... of radiotherapy for chemodectomas Mayo Clin Proc 1992, 67:537-540 doi:10.1186/1477-7819-8-76 Cite this article as: Hafez et al.: The safety and efficacy of gamma knife surgery in management of...

Ngày tải lên: 09/08/2014, 03:22

... weeks of ART (P > 0.05) Group A patients had a median CD4 cell count of 85, 125, 158 and 198 cells/mm3 and group B patients had a median CD4 of 240, 280, 305 and 331 cells/mm3 at 12, 24, 36 and ... initiation of a FDC of d4T/3TC/NVP in HIV-infected patients with baseline CD4 cell count of

Ngày tải lên: 10/08/2014, 05:20

... assessed the duration of drainage, the day of maximum loss of chylous and the type and duration of treatment (fatty acidfree MCT-enriched diet, TPN, octreotide, recanalisation of thrombosed veins ... in newborns and infants – risk factors and efficacy of MCT-diet Journal of Cardiothoracic Surgery 2010 5:127 Submit your next manuscript to BioMed Central and take full advantage of: • Convenient ... transposition of the great vessels, DORV = double outlet right ventricle, TOF = Tetralogy of Fallot, CoA = coarctation of the aorta; ALVS = aorto left ventricular shunt Biewer et al Journal of Cardiothoracic...

Ngày tải lên: 10/08/2014, 09:23

... maximum rate of 60 µg kg-1 h-1 and/ or additional boluses and/ or increases in the infusion rate of propofol up to a maximum dose of mg kg-1 h-1 to attain and then maintain optimum analgesia and sedation ... effects of remifentanil compared with those of alfentanil [8] and fentanyl [9] are similar; remifentanil also has a safety profile similar to that of other opioids [8-10] The predictable offset of ... and sedation beyond day 3, propofol was discontinued and replaced with midazolam in accordance with local transitioning protocols The infusion rates of fentanyl and morphine and bolus doses and...

Ngày tải lên: 12/08/2014, 20:20

... dose of 20 mg during the course of the study All 14 subjects who were randomized to placebo and completed weeks of treatment had their "dose" of blinded medication "increased" to 20 mg The rate of ... by a clinical evaluation by a child and adolescent psychiatrist Specification of abuse disorder (abuse vs dependence), age of onset of symptoms, and length of illness were based on data obtained ... a group of youths who were at risk for ongoing substance abuse, the dose of fluoxetine used in this study was limited to a maximum of 20 mg/day Although the efficacy of higher doses of fluoxetine...

Ngày tải lên: 13/08/2014, 18:21

... damage of HIV and TB as well as HIV/TB coinfection Expanding and deploying of intervention programs on HIV infection such as giving out clean needles and condoms Expanding medical gridlines and ... 14,769 and (incubatory oral fluid) techniques; 09 studies with total samples of 6,562 and lung x-ray and incubatory oral fluid techniques; 01 study with total samples of 161 and lung x-ray and Mantoux ... noted that 88.3% of them were once IDUs and 40.2% of them had shared needles 4.3 Assessment on efficacy of community intervention measures for IDUs group The efficacy study of community intervention...

Ngày tải lên: 04/10/2014, 12:44

... EDUCATION AND TRAINING MINISTRY OF HEALTH NATIONAL INSTITUTE OF HYGIENE AND EPIDEMIOLOGY *************** PHAM THI DUNG THE SITUATION OF INCREASING SERUM URIC ACID, RELATED FACTORS AND EFFICACY OF DIETARY ... BMI, use of red meat, organ meats, bone soup and use of soft drink regularly In female, we eliminated factors of using alcohol and using bone soup in the analysis as less frequent use of these ... group of 70-79 and 4.5 times in the age group of 80 and older as compared to the age group of 30 Our results were consistent with epidemiological studies in Vietnam and oversea Assessment of the...

Ngày tải lên: 21/10/2014, 20:53

... DEGREE OF MASTER OF SCIENCE DEPARTMENT OF MEDICINE NATIONAL UNIVERSITY OF SINGAPORE 2003 ACKNOWLEDGEMENTS With special thanks: To Prof Lim Tow Keang and consultant Dr Malcolm, for their professional ... Department of Emergency Medicine, National University Hospital i TABLE OF CONTENTS ACKNOWLEDGEMENTS i TABLE OF CONTENTS ii LIST OF TABLES AND FIGURES iv Summary of the ... a multitude of presentations and, most likely, a multitude of causes Traditionally, asthma has been regarded as a manifestation of an underlying abnormality of airway smooth muscle and its neural...

Ngày tải lên: 26/09/2015, 11:07

... region of Der p and Der p clones were amplified using DP2F-DP2R and DP5F-DP5R forward and reverse primer pairs The clones of Der p and Der p were amplified using AFTF-DP1R and AFTF-DP7R forward and ... EXPRESSION AND PURIFICATION OF HYBRIDS IN ESCHERICHIA COLI (BL21 STRAIN) 45 3.2.1 Expression and purification of Der p 1-2 45 3.2.2 Expression and purification of Der p 7-5 ... allergens and inhibited the binding of human serum IgE to them 77 4.4 COMPARISON OF INDIVIDUAL DER P AND HYBRID DER P 1-2 AS POTENTIAL VACCINES 84 v 4.4.1 Incorporation of Der p...

Ngày tải lên: 07/10/2015, 10:02

... of the antibody response titrations of 14 dpv and 28 dpv of vaccinated pigs by LPB-ELISA and protective effect in pigs were recorded in table The average titer at 14 dpv and 28 dpv was 1.50 and ... http://www.virologyj.com/content/7/1/215 Page of Table The results of the sera titers of 14 dpv and 28 dpv of vaccinated pigs by LPB-ELISA and protective effect in swine challenged with OH/99 No of pig 10 11 12 13 14 ... article as: Li et al.: Alternative way to test the efficacy of swine FMD vaccines: measurement of pigs median infected dose (PID50) and regulation of live virus challenge dose Virology Journal 2010...

Ngày tải lên: 12/08/2014, 01:21

... children aged 6-12 year and there was a significant reduction of pain in balloon group compared with distraction and control groups.8 This study evaluated the efficacy of Valsalva maneuver on ... projection pain and hemodynamic responses during spinal puncture Methods and Materials This randomized clinical trial was performed in Dr.Shariati Hospital of Tehran University of Medical Sciences ... mild pain, 2= moderate pain and 3= severe pain, and visual analog scale of 0–10, where 0=no pain and 10= worst imaginable pain Agrawal et al used both, 4-point scale and VAS, in which the first...

Ngày tải lên: 25/10/2012, 11:15

... comparative efficacy and tolerability of 5-Loxin® and Aflapin® in the treatment of OA of the knee Materials and Methods Study materials BE-30 (5-Loxin) is a novel Boswellia serrata extract standardized ... software to evaluate the efficacy of 5-Loxin® and Aflapin® in comparison with the placebo group in terms of improvement in pain and physical function scores at baseline and on days 7, 30, 60 and ... Hematological and biochemical evaluations For assessment of safety of 5-Loxin® and Aflaseveral parameters were evaluated in serum, urine and whole blood of all subjects at each visit of the study...

Ngày tải lên: 25/10/2012, 11:40

... Delhi city and validation of interior illuminance model Location and climatic conditions New Delhi is located in Northern part of India, a latitude 28.58o N and a longitude of 77.02o E and at an ... of rain The average temperatures are around 29oC (8 5oF) , although they can vary from around 25oC (7 8oF) on rainy days to 32oC (9 0oF) during dry spells The monsoons recede in late September, and ... global luminous efficacy is 108.0 lm/W and the yearly average diffuse luminous efficacy is 136.5 lm/W Diffuse luminous efficacy is higher than the global efficacy in the sky type of the area indicating...

Ngày tải lên: 05/09/2013, 16:10

... properties of nonreplicating vectors and biological response modifiers by direct intra-nodal administration of plasmid and peptide [19,41] We showed that the sequence and the route of administration of ... treatment of diseases such as HIV, other microbes and cancer [11,22-37] In addition, such protocols offer a more Page of 11 practical alternative for active immunotherapy of cancer and other ... immune profile of peptide epitopes and biological response modifiers in their simplest form Intriguingly, a rather low dose of peptide co-administered with robust doses of CpG (TLR9 ligand) resulted...

Ngày tải lên: 18/06/2014, 16:20

... quantitative analysis of m-RNA of bcl-2 by RT-PCR confirmed the highest efficacy of the combination in reducing the expression of the targeted gene (Figure 4C and 4D) Apoptosis and proliferation ... marked antitumoral effect with a TWI of more than 50% and 20 days of TRD being observed Table Antitumor efficacy of G3139 alone or in combination with chemotherapy and EP on M14 melanoma-bearing mice ... antitumor efficacy of the treatments was assessed by the following end-points: a) percent of tumor weight inhibition (TWI%), calculated as [1(mean tumor weight of treated mice/mean tumor weight of controls)]...

Ngày tải lên: 18/06/2014, 22:20

... quantitative analysis of m-RNA of bcl-2 by RT-PCR confirmed the highest efficacy of the combination in reducing the expression of the targeted gene (Figure 4C and 4D) Apoptosis and proliferation ... marked antitumoral effect with a TWI of more than 50% and 20 days of TRD being observed Table Antitumor efficacy of G3139 alone or in combination with chemotherapy and EP on M14 melanoma-bearing mice ... antitumor efficacy of the treatments was assessed by the following end-points: a) percent of tumor weight inhibition (TWI%), calculated as [1(mean tumor weight of treated mice/mean tumor weight of controls)]...

Ngày tải lên: 20/06/2014, 04:20