6 il 8 and mcp 1 gene expressions in activated mast cells
Báo cáo y học: "Baicalein inhibits IL-1β- and TNF-α-induced inflammatory cytokine production from human mast cells via regulation of the NF-κB pathway" pot
... the gene expression of IL -6, IL- 8, and MCP- 1 in IL- 1 - and TNF-α -activated HMC -1 cells RT-PCR RT-PCR analysis of effects of BAI on the gene expression of IL -6, IL- 8, and MCP- 1 in IL- 1 - and TNF-α -activated ... production of IL -6, IL- 8, and MCP- 1 Effects from TNF-α -activated HMC -1 cells Effects of Baicalein (BAI) on production of IL -6, IL- 8, and MCP- 1 from TNF-α -activated HMC -1 cells To each well of a 6- well ... assayed for cytokines by ELISA The results are shown in Fig IL- 1 at 10 ng/mL concentration markedly induced IL -6, IL- 8, and MCP- 1 production from HMC -1 (3 26. 7 ± 8. 0, 3 68 .1 ± 19 .1, and 432.4 ± 40.9...
Ngày tải lên: 13/08/2014, 13:22
Báo cáo khoa học: Human airway trypsin-like protease induces amphiregulin release through a mechanism involving protease-activated receptor-2-mediated ERK activation and TNF a-converting enzyme activity in airway epithelial cells doc
... M (19 94) Grb2 ⁄ Ash binds directly to tyrosines 1 0 68 and 10 86 and indirectly to tyrosine 11 48 of activated human epidermal growth factor receptors in intact cells J Biol Chem 269 , 313 10– 313 14 ... activates the mitogen -activated protein kinase ⁄ activator protein -1 pathway in human peripheral blood eosinophils, causing cytokine production and release J Immunol 16 9 , 266 2– 266 9 Scmidlin F, Amadesi ... airway trypsin-like protease on 63 98 13 14 15 16 17 intracellular free Ca2+ concentration in human bronchial epithelial cells J Med Invest 50, 95 10 7 Schmidlin F & Bunnett NW (20 01) Protease-activated...
Ngày tải lên: 30/03/2014, 11:20
báo cáo hóa học: " The impact of shift work induced chronic circadian disruption on IL-6 and TNF-a immune responses" pot
... 0.0 06 0.099 0.9 21 BMI 0.025 0.447 0 .65 6 Shift work 0. 010 0. 1 68 0. 86 6 TNF-a p Age - 0.0 16 - 0.275 0. 783 Smoking - 0.022 - 0.400 0 .69 0 sleep quality 0. 014 0.239 0 . 81 1 BMI - 0.043 - 0.7 71 0.4 41 Shift ... (ß) with IL -6, TNF-a and lymphocytes in multiple regression analysis Component Factor ß t IL -6 BMI 0 .10 3 1 .84 2 0. 066 Shift work 0.049 0 .82 0 0. 413 Age Smoking 0.0 06 0 .10 0 0 .10 3 1. 794 0.9 18 0.074 ... 2.30 2 .67 1. 54 3.79 0.2 76 TNF-a Daytime workers Shift workers 5. 58 5 . 68 2. 91 5 .19 0 .84 1 Lymphocytes Daytime workers Shift workers 33 . 68 32.99 7 .64 7.49 0.404 Component PSQI Mean SD p IL -6 PSQI...
Ngày tải lên: 20/06/2014, 00:20
báo cáo khoa học: " Effects of ulinastatin and docataxel on breast tumor growth and expression of IL-6, IL-8, and TNF-a" doc
... h s) s) Inhibition rate (%) A value ( x 1. 366 ± 0.042 1 .88 1 ± 0 .1 06 7. 919 0. 86 7 ± 0 .10 2a 36. 530 0 .63 1 ± 0. 067 a 66 .454 21. 455 0.703 ± 0.043a,b 48. 5 36 0.440 ± 0. 063 a,b 76. 6 08 28. 8 21 0.590 ± 0.059a,b,c ... Mean tumour inhibition (%) Control 0.5 51 ± 0.0 26 4.257 ± 0. 212 UTI 0. 563 ± 0. 012 3. 16 6 ± 0 .13 4 29. 312 TAX 0.592 ± 0.0 18 1. 1 06 ± 0 .14 5 86 . 0 21 UTI +TAX 0. 589 ± 0.0 21 0 .62 7 ± 0.0 16 98. 264 Zhao et ... Biol 2009, 22(9): 86 5 - 86 8 doi :10 .11 86 / 17 56- 9 966 -30-22 Cite this article as: Zhao et al.: Effects of ulinastatin and docataxel on breast tumor growth and expression of IL -6, IL- 8, and TNF-a Journal...
Ngày tải lên: 10/08/2014, 10:21
Báo cáo y học: "Effects of cigarette smoke on degranulation and NO production by mast cells and epithelial cells" pot
... Nicotine(µM) A549 Cell Line AEC Cells NHTBE Cell Line 31. 25 62 .5 12 5 250 67 .0 ± 5.79* 11 2 .8 ± 25. 06 87 .9 ± 8 . 61 65 .0 ± 7 .87 * 12 0.2 ± 9.70 83 .4 ± 10 .53 69 .8 ± 7 .12 * 10 5.7 ± 20 . 68 87 .9 ± 3.37 69 .4 ... 2005, 6: 1 08 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 Takeno S, Osada R, Furukido K, Chen JH, Yajin K: Increased nitric oxide production in nasal epithelial cells from ... cells declined from 1 .60 to 1. 29 (t = 8. 9 31, p = 0. 012 , paired t test, two-tailed) Similarly, eNOS positive RBL-2H3 cells were decreased after 1% CSS treatment from 2. 78 to 2.24 ± 0 .17 iNOS and...
Ngày tải lên: 12/08/2014, 18:22
Báo cáo khoa học: "Macrophages, myofibroblasts and mast cells in a rat liver infected with Capillaria hepatica" ppsx
... hepatica-infected rats Mem Inst Oswaldo Cruz 20 01, 96, 10 01- 1003 10 Ramos SG, Montenegro AP, Goissis G, Rossi MA Captopril reduces collagen and mast cell and eosinophil accumulation in pig serum-induced rat ... myofibroblasts and mast cells in carbon tetrachloride-induced rat liver cirrhosis Anticancer Res 2002, 22, 86 9 -87 7 Laskin DL Non parenchymal cells and hepatotoxicity Semin Liver Dis 19 90, 10 , 293-304 ... Li CY, Baek JY Mastocytosis and fibrosis: role of cytokines Int Arch Allergy Immunol 2002, 12 7, 12 3 -1 26 Neafie RC, Connor DH, Cross JH Capillariasis (intestinal and hepatic) In: Binford CH, Connor...
Ngày tải lên: 07/08/2014, 20:23
Báo cáo y học: " Eradication of intractable malignant ascites by abdominocentesis, reinfusion of concentrated ascites, and adoptive immunotherapy with dendritic cells and activated killer cells in a patient with recurrent lung cancer: a case report" pps
... 4 21 79 25 23 36 61 82 5 14 1 2.7 85 2 .6 0.3
Ngày tải lên: 11/08/2014, 19:21
Báo cáo khoa học: Recombinant bovine zona pellucida glycoproteins ZP3 and ZP4 coexpressed in Sf9 cells form a sperm-binding active hetero-complex ppt
... bovine ZP4 cDNA as template The ZP4 mutants rZP 41 36) 464 and rZP4 18 2 ) 464 correspond to regions Asp1 36 to Arg 464 and Gly 18 2 to Arg 464 , respectively The 5¢-sense primers contained SmaI sites, and ... rZP 41 36) 464 mutant lacks residues Lys25 to Pro135 and consists of the trefoil and ZP domains of rZP4 The rZP4 18 2 ) 464 mutant lacks residues Lys25 to Tyr 18 1 and thus consists only of the ZP domain ... sequencing [6, 19 – 21] , are 77%, 85 % and 75% identical, respectively The mature porcine and bovine ZP4 polypeptides differ in that an N-terminal region corresponding to residues 1 13 5 of bovine ZP4...
Ngày tải lên: 07/03/2014, 05:20
Báo cáo Y học: Incorporation of 3-nitrotyrosine into the C-terminus of a-tubulin is reversible and not detrimental to dividing cells potx
... nitrotyrosine into tubulin was determined in 0 .1 mL-aliquots (.): lCiÆmL )1 (6. 7 lM) [14 C]nitrotyrosine; (d): lCiÆmL )1 (1 mM) [14 C]nitrotyrosine; (j): lCiÆmL )1 (6. 7 lM) [14 C]nitrotyrosine plus 0 .1 mM ... Sci 11 1, 17 1– 18 1 29 Liu, J.S., Zhao, M.L., Brosnan, C.F & Lee, S.C (20 01) Expression of inducible nitric oxide synthase and nitrotyrosine in multiple sclerosis lesions Am J Pathol 1 58, 2057–2 066 ... to incorporate [14 C]-tyrosine into endogenous tubulin [22, 26] Under similar conditions, [14 C]-3-nitrotyrosine (6. 7 lM, )1 450 lCiÆlmol ) was incorporated into protein (Fig 1A) Inclusion of mM...
Ngày tải lên: 17/03/2014, 10:20
Báo cáo Y học: Group IID heparin-binding secretory phospholipase A2 is expressed in human colon carcinoma cells and human mast cells and up-regulated in mouse inflammatory tissues doc
... Biol Chem 2 76, 11 1 26 11 134 Enomoto, A., Murakami, M & Kudo, I (2000) Internalization and degradation of type IIA phospholipase A2 in mast cells Biochem Biophys Res Commun 2 76, 66 7 67 2 Koduri, ... M., Yoshihara, K., Singer, A., Valentin, E., Ghomashchi, 13 14 15 16 17 18 19 20 21 22 23 24 25 26 F., Lambeau, G., Gelb, M.H & Kudo, I (20 01) Distinct arachidonate-releasing functions of mammalian ... A2 J Biol Chem 274, 1 18 8 1 1 18 8 8 Tojo, H., Ono, T., Kuramitsu, S., Kagamiyama, H & Okamoto, M (1 988 ) A phospholipase A2 in the supernatant fraction of rat spleen: its similarity to rat pancreatic...
Ngày tải lên: 18/03/2014, 01:20
Báo cáo khoa học: Saporin and ricin A chain follow different intracellular routes to enter the cytosol of intoxicated cells pptx
... HeLa ID50 Toxin exposures – + pM Ricin nM Saporin Ricin-6K (4 h) Ricin ( 18 h) Saporin ( 18 h) 17 .4 ± 16 . 8 ± 4 .8 214 0 pM 0 .19 9 pM 17 .6 nM 6. 8 ± 20.5 ± 7.3 33.4 pM 0.0997 pM 5.3 nM Chloroquine Cell ... (19 97) Retrograde transport of mutant ricin to the endoplasmic reticulum 4993 Saporin trafficking in intoxicated mammalian cells 10 11 12 13 14 15 16 17 18 19 20 21 22 with subsequent translocation ... (n ¼ 6) HeLa ID50 (6 h) Toxin exposures – + pM Ricin nM Saporin Ricin RTA-KDEL Saporin 30.4 ± 9 .8 19 ± 5 .6 3.3 pM 33.4 nM 210 0 nM 89 .3 ± 7 .1 34 ± 12 > 17 00 pM > 16 7 0 nM 19 40 nM Proteasome inihibitors...
Ngày tải lên: 23/03/2014, 15:21
Báo cáo Y học: Repression of FasL expression by retinoic acid involves a novel mechanism of inhibition of transactivation function of the nuclear factors of activated T-cells pptx
... death gene Cell Death Differ 6, 11 74 1 18 1 Nagata, S (19 99) Fas ligand-induced apoptosis Annu Rev Genet 33, 29–55 Dhein, J., Walczak, H., Baumier, C., Debatin, K.-M & Krammer, P.H (19 95) Autocrine ... Flag-NFATp and NFATZH This work was supported by a grant (KRF-99– 015 DP03 98) from the Korea Research Foundation to M.-O L and J P 10 11 12 13 14 17 REFERENCES Pinkoski, M.J & Green, D.R (19 99) Fas ligand, ... lM) with PMA (10 ngÆmL )1) and ionomycin (0.5 lM); E, CsA (1 lgÆmL )1) with PMA (10 ngÆmL )1) and ionomycin (0.5 lM) DISCUSSION Although it has been convincingly documented that RA induces the repression...
Ngày tải lên: 24/03/2014, 03:21
Báo cáo sinh học: " No relationship between the distribution of mast cells and the survival of stage IIIB colon cancer patients" pdf
... 12 10 11 11 10 12 18 13 Pushing 31 15 16 18 13 16 15 Infiltrating 62 30 32 Growth type Invasive depth T3 T4 1. 000 0. 769 16 15 11 0.239 17 14 30 32 0 . 68 3 0.0 01 26 36 0.293 0. 769 28 34 0.2 41 30 ... 0.9 98 0.4 71 0.250 28 26 34 39 11 0.799 26 26 32 P 23 20 20 15 22 17 0 .65 2 37 36 0 .12 1 0.094 21 33 17 22 0.732 Papillary + tubular 17 18 0.3 36 MCClnwm
Ngày tải lên: 18/06/2014, 19:20
Báo cáo hóa học: " Hantaviruses and TNF-alpha act synergistically to induce ERK1/2 inactivation in Vero E6 cells" docx
... MEK/ERK and protein kinase A in virus multiplicitation J Biol Chem 20 01, 2 76: 383 53- 38 360 Page of (page number not for citation purposes) Virology Journal 20 08, 5 :11 0 18 19 20 21 22 23 24 25 26 27 28 ... Journal 20 08, 5 :11 0 http://www.virologyj.com/content/5 /1/ 110 Figure TULV inhibits ERK1/2 cell survival pathway in Vero E6 cells TULV inhibits ERK1/2 cell survival pathway in Vero E6 cells A In order ... mitogen -activated protein kinase signal transduction pathway J Virol 2005, 79 :11 366 -11 3 81 Kang JI, Park SH, Lee PW, Ahn BY: Apoptosis is induced by hantaviruses in cultured cells Virology 19 99, 264 :99 -10 5...
Ngày tải lên: 20/06/2014, 01:20
báo cáo hóa học:" No relationship between the distribution of mast cells and the survival of stage IIIB colon cancer patients" potx
... 12 10 11 11 10 12 18 13 Pushing 31 15 16 18 13 16 15 Infiltrating 62 30 32 Growth type Invasive depth T3 T4 1. 000 0. 769 16 15 11 0.239 17 14 30 32 0 . 68 3 0.0 01 26 36 0.293 0. 769 28 34 0.2 41 30 ... 0.9 98 0.4 71 0.250 28 26 34 39 11 0.799 26 26 32 P 23 20 20 15 22 17 0 .65 2 37 36 0 .12 1 0.094 21 33 17 22 0.732 Papillary + tubular 17 18 0.3 36 MCClnwm
Ngày tải lên: 20/06/2014, 03:20
Báo cáo khoa học: "Role of mucosal mast cells in visceral hypersensitivity in a rat model of irritable bowel syndrome" ppt
... J, Bueno L Role of kinin B1 and B2 receptors and mast cells in post intestinal infection-induced hypersensitivity to distension Neurogastroenterol Motil 19 98, 10 , 499-5 08 19 Mertz H, Naliboff ... Bunnett NW Mast cell tryptase regulates rat colonic myocytes through proteinaseactivated receptor J Clin Invest 19 97, 10 0, 1 383 -13 93 11 Dunlop SP, Jenkins D, Spiller RC Distinctive clinical, 323 ... Gut 2000, 47, 80 4 81 1 24 Stead RH, Tomioka M, Quinonez G, Simon GT, Felten SY, Bienenstock J Intestinal mucosal mast cells in normal and nematode-infected rat intestines are in intimate contact...
Ngày tải lên: 07/08/2014, 18:20
Báo cáo y học: "Controlling Osteogenesis and Adipogenesis of Mesenchymal Stromal Cells by Regulating A Circadian Clock Protein with Laser Irradiation" pptx
... photoreceptors hCRY1 and hCRY2 are flavoproteins Biochemistry 19 96; 35 :1 387 1 1 387 7 [5] Young MW Circadian rhythms Marking time for a kingdom Science 2000; 288 : 4 51- 453 [6] Shearman LP, Sriram S, Weaver DR, ... homologs in mouse and human cells Nucleic Acids Res 19 98; 26: 50 86 - 5092 [17 ] Young MW, Kai SA Time zones: a comparative genetics of circadian clocks Nature Rev Genet 20 01; 2:702- 715 [ 18 ] Kawasaki S, ... 1 966 ; 210 : 411 -4 18 [20] Gundberg CM, Markowitz ME, Mizruchi M, Rosen JF Osteocalcin in human serum: a circadian rhythm J Clin Endocrinol Metab 1 985 ;60 :7 36- 739 [ 21] Spiegelman BM Flier JS Obesity and...
Ngày tải lên: 08/08/2014, 17:20
Báo cáo y học: "Significance of Conversation between Mast Cells and Nerves" pdf
... Chem 1 987 ; 262 :1 363 –73 1 06 Silver R, Silverman AJ, Vitkovic L, Lederhendler II Mast cells in the brain: evidence and functional significance Trends Neurosci 19 96; 19 :25– 31 107 Persinger MA Brain mast ... are released, including prostaglandins and leukotrienes In the late-phase allergic response, cytokines such as interleukin (IL) -4, IL- 5, IL -6, IL- 8, IL- 13 , and TNF are induced and secreted.30 ... axis in dogs J Exp Med 20 01; 194: 71 8 11 0 Mares V, Bruckner G, Biesold D Mast cells in the rat brain and changes in their number under different light regimens Exp Neurol 19 79 ;65 :2 78 83 11 1 MacQueen...
Ngày tải lên: 08/08/2014, 20:23