6 making stem cells home better

... factor expression in stem cells has been used to greatest effect to generate nonendocrine cells Thus, a few examples of directed differentiation of stem cells into nonendocrine cells are described ... differentiation 3.1.3 INSULIN-SECRETING CELLS FROM TISSUE STEM CELLS An alternative approach to using ES cells is to redirect the differentiation of adult stem cells along an islet lineage One means ... and beta cells Proc Natl Acad Sci USA 2003;100:12660–12665 Chapter / Transcription Factor-Directed Differentiation of Stem Cells 133 Transcription Factor-Directed Differentiation of Stem Cells...

Ngày tải lên: 10/08/2014, 18:21

... macrophages or NK cells activate T lymphocytes to proliferate Cytotoxic T cells are responsible for eliminating foreign cells or cells infected with viruses The proliferation of cytotoxic T cells can ... proinflammatory cytokine release from injured cells or antigen-presenting cells (macrophages or natural killer cells) These cytokines stimulate parenchymal cells to produce chemokines that recruit ... EFFECTS OF ADIPOSE STEM CELLS Tumor necrosis factor-induced protein (TSG-6) has been shown to mitigate inflammation Its presence in the secretome of adipose stem / stromal cells (ASC) and its...

Ngày tải lên: 24/08/2014, 11:56

... Flk-1+CD31-CD34- mesenchymal stem cells: feasibility and safety from monkey to human Stem Cells Dev,2006,15(3):349-357 Devine SM, Bartholomew AM, Mahmud N, et al Mesenchymal stem cells are capable of ... transplantation of stem cells, it is very important to observe the survival and curative effects of transplanted stem cells Traditional immunohistochemical method can easily identify the transplanted cells ... expressed in injured tissues play important roles (2) Stem cells circulate among tissues, and stem cells migrate to the injured tissues once injury occurs Stem cell homing is a complicated process in...

Ngày tải lên: 25/10/2012, 11:18

... efficient and safe xeno-free cryopreservation method for the storage of human embryonic stem cells Stem Cells 2004;22(5):779-89 10 Speicher MR, Ballard SG, Ward DC Karyotyping human chromosomes ... some cells detached after exposure to low temperature Virtually all of the detached cells were determined to be non-viable with tryphan blue staining (data not shown) All of the detached cells ... so as to enable some of the cells to undergo mitosis Mitotic hESC were then arrested at metaphase by colcemid treatment (0.1 μg/ml) for 16-18 h Subsequently, the cells were subjected to hypotonic...

Ngày tải lên: 31/10/2012, 16:57

... new Hue clothes Sorry, You’re Congratulation! not correct! You’re right! Nha Trang Ha Long Bay HOMEWORK : -Learn by heart A4 and A5 -Prepare section B ...

Ngày tải lên: 18/09/2013, 14:10

... Lab 3.1.6 Enable Secret password Enable/VTY/Console passwords Cisco1 Copyright  2003, Cisco Systems, Inc b To change information, go to the proper command mode and retype the command with the ... the router off 3-5 CCNA 2: Routers and Routing Basics v 3.0 - Lab 3.1.6 Copyright  2003, Cisco Systems, Inc Erasing and reloading the router Enter into the privileged EXEC mode by typing enable ... startup-config Router#erase startup-config The responding line prompt will be: Erasing the nvram filesystem will remove all files! Continue? [confirm] Press Enter to confirm The response should be: Erase...

Ngày tải lên: 11/12/2013, 13:15

... to the host 2-5 CCNA 2: Routers and Routing Basics v 3.0 - Lab 3.1.6 Copyright  2003, Cisco Systems, Inc Step Bring down Serial interface a Bring the interface down for maintenance by entering: ... the router off 3-5 CCNA 2: Routers and Routing Basics v 3.0 - Lab 3.1.6 Copyright  2003, Cisco Systems, Inc Erasing and reloading the router Enter into the privileged exec mode by typing enable ... startup-config Router#erase startup-config The responding line prompt will be: Erasing the nvram filesystem will remove all files! Continue? [confirm] Press Enter to confirm The response should be: Erase...

Ngày tải lên: 11/12/2013, 13:15

Ngày tải lên: 07/01/2014, 15:28

... get into such things as a total memorized, word-for-word system of education, which will not result in the gain of any knowledge Such a system only produces graduates who can possibly parrot back ... In fact, in this second application, Scientology offers nothing less than practical methods to better every aspect of our existence—means to create new ways of life And from this comes the subject ... Chap 1.book Page Sunday, September 23, 2001 4:37 PM SCIENTOLOGY Making the World a Better Place Founded and developed by L Ron Hubbard, Scientology is an applied religious philosophy...

Ngày tải lên: 22/01/2014, 10:20

... mesenchymal stem cells and mononuclear cells Stem Cells 25, 1166–1177 Li L, Zhang S, Zhang Y, Yu B, Xu Y & Guan Z (2009) Paracrine action mediates the antifibrotic effect of transplanted mesenchymal stem ... mesenchymal stem cells Science 284, 143–147 Porada CD, Zanjani ED & Almeida-Porad G (2006) Adult mesenchymal stem cells: a pluripotent population with multiple applications Curr Stem Cell Res ... & Chen X (2008) Lysophosphatidic acid protects mesenchymal stem cells against hypoxia and serum deprivation-induced apoptosis Stem Cells 26, 135–145 21 Li Z, Wei H, Liu X, Hu S, Cong X & Chen...

Ngày tải lên: 18/02/2014, 04:20

... outcome in described stem cell types Stem cell type BMP signal outcome Embryonic stem cells (i) Embryonic stem cells (ii) Hair-cell progenitors (inner ear) Mesodermal progenitor cells Stemness upkeep ... embryonic stem cells J Cell Biol 138, 1207–1217 Sumi T, Fujimoto Y, Nakatsuji N & Suemori H (2004) STAT3 is dispensable for maintenance of self-renewal in nonhuman primate embryonic stem cells Stem Cells ... human embryonic stem cells Stem Cells 22, 770–778 Ying QL, Nichols J, Chambers I & Smith A (2003) BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal...

Ngày tải lên: 19/02/2014, 00:20

... ES cells and in human hematopoietic progenitor cells Discussion B Fig Transcription of LCR hypersensitive site in undifferentiated murine embryonic stem cells and in human CD 133+ bone marrow cells ... Rex-1 gene, primer sets span introns Day cells are composed of ES cells and MEF cells grown in ES media containing leukemia inhibitory factor (LIF) These cells express the Rex-1 and b-actin genes ... differentiation of murine embryonic stem cells PCR analysis of DNase I treated and reverse-transcribed total RNA extracted from differentiating embryonic stem cells at the indicated time points...

Ngày tải lên: 07/03/2014, 12:20

... Section Neural Stem Cells as Progenitor Cells Chapter Systems for ex-vivo Isolation and Culturing of Neural Stem Cells Simona Casarosa, Jacopo Zasso and Luciano Conti Chapter Neural Stem Cell Heterogeneity ... of stem cells in the tis‐ sue homeostasis is largely known and efficacious stem cell therapies are already available The most urgent question is whether and how the potential of neural stem cells ... Institute Cavalieri-Ottolenghi (NICO) Section Neural Stem Cells as Progenitor Cells Chapter Systems for ex-vivo Isolation and Culturing of Neural Stem Cells Simona Casarosa, Jacopo Zasso and Luciano...

Ngày tải lên: 08/03/2014, 19:20

... Shinya Yamanaka Stem Cells Make Copies of Themselves Through Cell Division, or … Stem Cells Adapt for Many Parts of the Body Stem Cells Brain Bone marrow Fat Heart Pancreas Pluripotent Stem Cell Sources ... Embryonic Stem Cells from Somatic Cell Nuclear Transfer (SCNT) If inner cell mass is placed in culture, the stem cells will divide Develops into a blastocyst Asexual production of pluripotent stem cells ... organisms composed of stable combinations of cells derived from different species Chimera Issues • Can human embr y onic stem cells differentiated into brain cells and inser t ed into mouse brain make...

Ngày tải lên: 13/03/2014, 16:29

... cells derived from cultured mouse ESCs are fat cells, various brain and nervous system cells, insulin-producing cells of the pancreas, bone cells, hematopoietic cells, yolk sac, endothelial cells, ... limited to only a few cell types: neural stem cells, including neural crest cells; hematopoietic stem cells; and pancreatic islet progenitors Neural stem cells, which are numerous in the fetal ... adult stem cells is the relationship of the cellular environment to the concept of plasticity in adult stem cells Markus Grompe showed that HSCs and pancreatic stem cells can give rise to liver cells...

Ngày tải lên: 15/03/2014, 09:20

... pluripotent stem cells (Takahashi and Yamanaka, 2006) To realize the full potential of embryonic and induced pluripotent stem cells, technologies, and especially those related to stem cell-based ... and more recently, of human induced pluripotent stem cells The exploration and realization of the incredible potential of these pluripotent stem cells for studying the fundamentals of early human ... Pluripotent Stem Cells Derivation and Culturing, summarizing 12 years of our team’s experience, skill and knowledge in the derivation, culture and expansion of human embryonic stem cells, and...

Ngày tải lên: 22/03/2014, 09:20

... Thaddeus G Golos 13 Reproductive Stem Cells of Embryonic Origin: Comparative Properties and Potential Benefits of Human Embryonic Stem Cells and Wharton’s Jelly Stem Cells 136 Chui-Yee Fong, Kalamegam ... mesenchymal stem cells Science 1999; 284:143–147 Goodman JW, Hodgson GS Evidence for stem cells in the peripheral blood of mice Blood 1962; 19:702–714 Gamete Generation from Stem Cells: Will ... embryonic stem ¨ cells Science 2003; 300:1251–1256 17 Novak I, Lightfoot DA, Wang H, et al Mouse embryonic stem cells form follicle-like ovarian structures but not progress through meiosis Stem Cells...

Ngày tải lên: 22/03/2014, 20:21

... of embryonic stem cells TE N Hattori and K Shiota ICM PGC TS cells Placental cells 77 ES cells 49 EG cells Embryonic cells Fig Epigenetic distances between ES cells and other stem cells derived ... profiles Epigenetic study of embryonic stem cells Differences in DNA methylation profiles between ES and other stem cells Comparing ES cells with other stem cells established from developing embryos ... the ED between ES and EG cells (49) is less than that between ES and TS cells (77), confirming the previous notion that EG cells are more similar to ES cells than to TS cells (Fig 1) Change of...

Ngày tải lên: 23/03/2014, 07:20

... mesenchymal stem cells of fetal or maternal origin from human placenta Stem Cells 22, 1338–1345 Bieback K, Kern S, Kluter H & Eichler H (2004) Critical parameters for the isolation of mesenchymal stem cells ... differentiation from stem cells For microarray analysis, we confirmed the hepatic differentiation of AT-MSC into hepatocyte-like cells using the original protocol (Fig 1A) The differentiated cells (AT-MSC-Hepa) ... into hepatic cells, the findings presented here suggest that MET might be a pivotal factor in determining stem cell transdifferentiation Discussion AT-MSCs may be good candidates as stem cells for...

Ngày tải lên: 30/03/2014, 04:20

... (slowly dividing astroglial cells and the bona fide adult neural stem cells) , type C cells (transit-amplifying cells derived from asymmetric division of Type B cells) , type A cells (immature neuroblasts ... orders@intechweb.org Neural Stem Cells and Therapy, Edited by Tao Sun p cm ISBN 978-953-307-958-5 Contents Preface IX Part Chapter Characterization of Neural Stem Cells Neural Stem Cells from Mammalian ... glial fibrillary acidic protein-positive cells from the adult central nervous system results in the loss of forebrain neural stem cells but not retinal stem cells Eur J Neurosci, Vol 18, No 1, (July...

Ngày tải lên: 30/03/2014, 23:20