5new developments in medical research and ethical implications

... ruler and color/gray charts should be acquired at the beginning and the end of each working session, keeping in mind the need to maintain the image acquisition conditions strictly constant during ... AIMS AND SCOPE OF DEVELOPMENTS IN PALEOENVIRONMENTAL RESEARCH SERIES Paleoenvironmental research continues to enjoy tremendous interest and progress in the scientific community The overall aims and ... They include among other things, the characteristics and settings of the acquisition device (e.g., depth of field, current intensity in a SEM filament) and any event occurring during the working...

Ngày tải lên: 03/06/2014, 01:32

... generally considered inaccurate and manual sleep staging remains the preferred option Even manual sleep staging may be subjective, particularly in identifying drowsiness and sleep onset in stage All ... those pertaining to sleep measurement in adult patients during their critical care admission and published in full in English Study comparing different sleep measurement techniques In the context ... Orr and Stahl (1977) [17] Richards and Bairnsfathera (1988) [20] 10 Hilton (1976) [16] Karacan et al (1974) [15] Medical Medical Medical Burns Medical Trauma Medical Surgical Medical Surgical Medical...

Ngày tải lên: 13/08/2014, 08:20

... responsibility for staff training by conducting disaster and disaster-related courses and training The involvement of the same people in both planning for emergencies and disasters, training the staff for ... the duration and intensity of consequent activities varied The data concerning the increase in mass-gatherings and sport events in the region are vital for planning and distributing the regional ... teenagers The following investigation revealed certain short-comings regarding the medical response, recognizing the need of a regional point of contact ("POC") and command and control centre...

Ngày tải lên: 25/10/2012, 09:56

... the weak financial markets and administrative interest rates are the overriding feature in most of the developing countries In most developing countries the nominal interest rate is institutionally ... the mining industry was mainly zinc production in Khammouane province Transport and communication was difficult, creating barriers for the distribution of goods and people domestically and internationally ... stability The findings will be useful for central bankers to understand the factors influencing money demand in the Lao PDR, especially taking into account of dollarization problems prevailing in the...

Ngày tải lên: 18/01/2014, 02:01

... 1990s Since then research and practice in digital libraries has become standard Plenty research funding, especially in the United States and United Kingdom, have made sure that both researchers and ... viewed, retrieved and preserved and shared according to international standards Future Developments Problem solving As we have seen digital libraries are thriving and expanding their services ... being engaging in meaningful human interactions with students and researchers while on the same time performing machine-like investigations of network resourcers, constantly on the hunt for information...

Ngày tải lên: 24/01/2014, 00:20

... attention to ethical issues: I was researching decision making, in particular ethical issues and decision making I was also keeping a journal, reflecting on and re-examining my own thoughts, feelings, ... According to Denzin and Lincoln (1994), ‘qualitative researchers study things in their natural settings, attempting to make sense of, or interpret, phenomenon in terms of the meanings people bring ... variety of industry and academic contexts (Selvin, 1999; Selvin, 2003, Selvin & Buckingham Shum, 2002, Buckingham Shum & Selvin, 2000) In that time I have grown increasingly aware that doing such...

Ngày tải lên: 30/03/2014, 11:20

... British Medical Journal Publishers President’s Commission for the Study of Ethical Problems in Medicine and Biomedical and Behavioral Research (1981) Defining death: Medical, legal and ethical ... the Guillain Barre and the locked -in syndromes Guillain Barre syndrome (GBS) is an in ammatory disorder of nerves and nerve roots outside the brain and spinal cord In severe cases the in ammation ... genuine interdisciplinary progress A third reason that these are strange times is because, in what feels like an instant, we have moved from living in the present to living in the future Nothing...

Ngày tải lên: 12/05/2014, 17:05

... PRINCIPLES AND ADVANCED METHODS IN MEDICAL IMAGING AND IMAGE ANALYSIS This page intentionally left blank PRINCIPLES AND ADVANCED METHODS IN MEDICAL IMAGING AND IMAGE ANALYSIS ... courses in biomedical engineering and medical sciences The book is a unique combination of chapters describing the principles as well as state-of-the-art advanced methods in medical imaging and image ... ch02 FA CHAPTER Medical Imaging and Image Formation Atam P Dhawan Medical imaging involves a good understanding of imaging medium and object, physics of imaging, instrumentation, and often computerized...

Ngày tải lên: 05/06/2014, 11:52

... Chen, Ming-Huei Chu and Der-Ming Chry 19 Linear Programming in Database 339 Akira Kawaguchi and Andrew Nagel 20 Searching Model Structures Based on Marginal Model Structures 355 Sung-Ho Kim and ... a vector and A is a matrix in frequency-domain Equations (2) and (3) are in matricial form and correspond to convolutions in a time-domain The index n is the discrete time instant linked to the ... contain a graph spanning tree So it is possible to maintain network connectivity constraining every sensor just to maintain direct communication links that corresponds to the edges of a spanning...

Ngày tải lên: 27/06/2014, 06:20

... receptor NLRP3 (NOD-, LRRand pyrin domain-containing 3) and the PYHIN (pyrin and HIN200 domain-containing) family protein AIM2 (absent in melanoma 2) are two PRRs that survilliance intracelluar DAMPs ... future  research.   The  book  is  targeted  at  researchers  and clinicians  who  are  interested  in learning  about  new  advances  in the  understanding and treatment of AMD, and insights into future research of AMD.  ... (Martinon et al., 2009) NLRs contain a central nucleotide-binding oligomerization domain (NACHT), an N-terminal effector domain (pyrin domain, caspase-recruitment domain or BIR domain) and C-terminal...

Ngày tải lên: 27/06/2014, 15:20

... main factors or interaction RESULTS The results will be presented in three stages: 1) just prechilling, 2) after prechilling and drying and 3) prechilling, drying and storage for 18 months in ... with germination in nursery conditions The results are expressed as germination percentage (GP) in the laboratory or seedling emergence percentage (SEP) in the nursery and mean germination time ... arrival of the seeds in the laboratory = The seeds were tested in the laboratory, after receiving the dormancy breaking treatments, before and after drying and after 1, and years of storage After18...

Ngày tải lên: 08/08/2014, 14:21

... approved for this indication both in the European Community and the US Inflixmab is given as an intravenous infusion over the course of hours in a dose of mg/kg intially at weeks 0, and and then every ... uncoupling of inflammation and joint remodeling in a mouse model of spondyloarthritis Arthritis Rheum 2007, 56:489-497 van der Heijde D, Landewe R, Einstein S, Ory P, Vosse D, Ni L, Lin SL, Tsuji ... more of the following criteria: fulfilling the clinical symptom of inflammatory back pain, being positive for HLA-B27, or showing evidence of sacroiliitis by imaging [11] Analyzing 350 referred...

Ngày tải lên: 09/08/2014, 01:22

... pyrin domain (PYD) in other proteins that have homology with pyrin’s N-terminal sequence [12] Members of the death domain superfamily are involved in the assembly and activation of apoptotic and ... motif containing Page of 10 (page number not for citation purposes) four cysteine-rich domains, a transmembrane domain, and an intracellular death domain Binding of soluble circulating TNF causes ... abdominal pain occurs in 80%; and skin manifestations, including erythematous rash (Figure 2), oedematous plaques (often overlying areas of mylagic pain), and discrete reticulate or serpiginous lesions,...

Ngày tải lên: 09/08/2014, 01:22

... chemokines, and prostaglandins Proinflammatory cytokines, chemokines, and prostaglandins and some anti-inflammatory cytokines such as transforming growth factor-beta have been found in myositis muscle ... the induction of MHC class I and ER stress) In this context, the safety and benefits of physical training are interesting and there are sufficient scientific data to advocate exercise training ... response’ The folding, exporting, and processing of newly synthesised proteins, including the processing of MHC class I molecules, occur in the ER ER stress response could be induced as a protective...

Ngày tải lên: 09/08/2014, 13:21

... (NACHT, LRR, and pyrin domain-containing-3) inflammasome and lead to caspase-1 processing of pro-IL-1β Activation of the endothelium by IL-1β increases trafficking of neutrophils to the inflammatory ... Arthritis Research & Therapy Vol 10 No So tions for these findings include lifestyle and dietary changes brought about by increasing prosperity and increased life expectancy and age of the ... specklike protein containing a caspase-associated recruitment domain [CARD]) and a protein of the NLR (Nod/NACHT-LRR domains) family Because of its ability to initiate IL-1β processing and secretion,...

Ngày tải lên: 09/08/2014, 13:22

... within the spinal cord through the activity of inhibitory neurotransmitters, which include serotonin, norepinephrine, enkephalins, γ-amino butyric acid and adenosine A decrease in this pain inhibitory ... improvements in pain and other symptoms [62] Duloxetine is a norepinephrine and serotonin reuptake inhibitor Two 12-week randomized, double-blind, placebocontrolled trials have evaluated duloxetine in ... developed and clinical studies demonstrate the effectiveness of the α2δ ligands (pregabalin) and the serotonin and noradrenalin reuptake inhibitors (duloxetine and milnacipran) As our understanding...

Ngày tải lên: 09/08/2014, 14:21

... described in this edition are being extensively used in medical research and they find their way into the reports subsequently published in the medical press It is important that the medical research ... an expanding subject, with a continually developing body of techniques, and a steadily growing number of practitioners, especially in medical research organizations and the pharmaceutical industry, ... the continuity and cohesion of the presentation, and to extend the scope to cover many new ideas now being introduced into the analysis of medical research data We have tried to maintain the modest...

Ngày tải lên: 10/08/2014, 15:20

... intervals will include m, whilst in  5% x will be more than 1Á96 standard errors away from m (as in the fourth sample in Fig 4.6) and the interval will not include m Example 4.1, continued In ... other, the latter being achieved by an infinitely long interval in that direction It is customary to use symmetric intervals unless otherwise stated In the following sections, and in Chapter 5, these ... value in modelling certain symmetric frequency distributions or as an approximation to the binomial and Poisson distributions We shall note in §4.2 a central role in describing the sampling distribution...

Ngày tải lên: 10/08/2014, 15:20

... variances, s2 =n and s2 In this sense, precision has been gained by combining the information from the data and the prior information These results illustrate various points made in §6.1 First, ... Shrinkage The phenomenon of shrinkage was introduced in §6.2 and illustrated in several of the situations described in that section and in §6.3 It is a common feature of parameter estimation in ... to variance between individuals, and this may be achieved by increasing n In some studies of medical interventions, subjects are selected by preliminary screening tests as having high values of...

Ngày tải lên: 10/08/2014, 15:20

... terms being rearranged here so that the factors are introduced in order The main effects of B and C are defined in a similar way 9.3 Factorial designs 253 The two-factor interaction between A and ... easily obtained by multiplying together the coefficients for the corresponding main effects; and those for the three-factor interaction by multiplying the coefficients for ‰AŠ and ‰BCŠ, ‰BŠ and ‰ACŠ, ... of the factors having fixed effects and some having random effects If there is just one random factor (as with blocks in the example in the last paragraph), any main effect or interaction of the...

Ngày tải lên: 10/08/2014, 15:20