5 genetic association studies for complex traits

... recorded for this trait Moderate value for heritability indicates little scope for improvement through selection for these traits Srinivas et al., (2014) reported moderate heritability for fibre ... breeders for further improvement using these characters The mean data and range for different traits across the genotypes are presented in Table variability parameters for different traits across ... assortment for favourable genes and gene complexes The information regarding genetic variability and potential of genotypes, heritability in desirable traits provides reliable basis for the crop

Ngày tải lên: 17/03/2020, 20:21

... regimes, we have performed a genome-wide association study for different root parameters Roots contribute to water stress avoidance and are a still underexploited target for breeding purpose ... accessions) subcomponents The two associations with the highest significance were for root thickness on chromosome and for crown root number on chromosome 11 No common associations were detected between ... was highly significant for all of the traits The broad-sense heritability of the traits, ranging from 0.65 to 0.90, was moderate to high, with the exception of two related traits (deepest point

Ngày tải lên: 22/05/2020, 04:06

... genome-wide association studies [9] Although genome-wide association studies that generate dense genotype data are becoming increasingly practical, targeted association studies? ??such as candidate gene studies ... as (0.01,0.01) for cluster 1, (À0.02,–0.06) for cluster and (À0.04,0.01) for cluster (Figure 2) Impact of European American population structure on genetic association studies In association analyses ... markers that are highly informative for distinguishing these ancestries We demonstrate that this panel of markers can be used to correct for stratification in association studies that not generate

Ngày tải lên: 01/11/2022, 09:46

... September 2016 accepted: 23 December 2016 Published: 09 February 2017 Genome-wide association study for performance traits in chickens using genotype by sequencing approach Fábio Pértille1, Gabriel Costa Monteiro Moreira1, ... Gerson Barreto Mourão1, Mônica Corrêa Ledur3 & Luiz Lehmann Coutinho1 Performance traits are economically important and are targets for selection in breeding programs, especially in the poultry industry ... especially in the poultry industry To identify regions on the chicken genome associated with performance traits, different genomic approaches have been applied in the last years The aim of this study

Ngày tải lên: 04/12/2022, 10:36

... RESEARCH ARTICLE Open Access The Personality Inventory for DSM-5 Short Form (PID-5-SF): psychometric properties and association with big five traits and pathological beliefs in a Norwegian population ... reliability and structural validity The associations with FFM traits and pathological personality beliefs were conceptually coherent and similar for the two forms of the PID-5 Conclusions: The results ... of these traits The PID5 is the result of three waves of data collection in which 37 maladaptive personality traits were reduced to 25 traits to be included in the instrument [30] These traits

Ngày tải lên: 10/01/2020, 14:46

... used for computing diversity indices (XLSX 102 kb) Additional file 5: Table S4 Phenotypic data for five traits and genotypic data at 20 SSRs, for the association panel Genotypic data at 20 SSRs for ... in linkage disequilibrium and genome-wide association studies, corresponding matrices were calculated for the association and wild panels together, i.e for a total of 334 individuals, based on ... background markers for relationship estimation in association mapping Plant Genome 2009;2:63–77 36 Gao X, Starmer J, Martin ER A multiple testing correction method for genetic association studies using

Ngày tải lên: 22/05/2020, 04:09

... character association of traits in F2 populations of rice from the cross BPT-5204 x WAB 450 for grain yield and its component characters In general, the PCV was higher than the GCV for all the traits ... appropriate formula for comparing individual line means Correlation analysis To estimate the degree of association between the traits studied, phenotypic correlation was computed by using the formula ... regard to specific traits Incidentally the parental lines used for developing mapping populations were also divergent for many of the trait related to productivity Therefore, an effort was made to

Ngày tải lên: 06/08/2020, 00:29

... two loci For case-control studies of genetic association, researchers 12,13 have found that, for a particular error model (not presented here), errors lead to a loss in power to detect association ... genetic case-control association studies for multiple disease models, although other authors6,14-17 have developed methods that allow for errors in genetic linkage and/or association analyses ... monotonically as D’ decreases to 0.5 for all studies Introduction Single nucleotide polymorphisms (SNPs) may be used in case-control designs to test for genetic association between marker and disease

Ngày tải lên: 18/10/2022, 13:47

... (SNP) markers was used for genome-wide association study (GWAS) for six stalk lodging resistance-related traits The heritability of all traits ranged from 0.59 to 0.72 in the association mapping ... environment were both significant for six traits in the association mapping panel (Table 2) For the association mapping panel, the broad-sense heritability (h2B) of all traits in low and high plant ... type [20] Genome-wide association study (GWAS) is a powerful tool for analyzing the genetic basis of complex traits So far, GWAS has been used to analyze many agronomic traits such as plant height,

Ngày tải lên: 30/01/2023, 21:03

... thresholds for all the traits than the 50 K SNP panel as summarized in Table 2, indicating that the 7.8 M sequence variant panel improved the power of GWAS to detect associations for the traits Therefore, ... per DNA variant for all the traits examined while missense, 5’UTR and other regulatory region variants accounted for relatively more additive genetic variance per sequence variant for RFI and ADG, ... wide association studies, Feed efficiency, Beef cattle Background Improving animal meat production efficiency has become an imperative goal for the industry to achieve as the global demand for

Ngày tải lên: 28/02/2023, 08:02

... from 31,909 for REA to 34,227 for AFAT The majority of the suggestive SNPs identified by the 50 K SNP panel GWAS for the five carcass merit traits (ranging from 85% for AFAT to 91% for CMAR) were ... association studies (GWAS) were conducted on 7,853,211 imputed whole genome sequence variants in a population of 3354 to 3984 animals from multiple beef cattle breeds for five carcass merit traits ... architecture, Imputed whole genome sequence variants, Genome wide association studies, Carcass merit traits, Beef cattle, Background Carcass merit traits are important to beef production as they directly

Ngày tải lên: 28/02/2023, 08:02

... decapod crustacean In this study, we report for banana shrimp genetic parameters for morphometric traits and, the first time for any shrimp, parameter estimates for body colour Ten highly polymorphic ... were firstly performed to detect possible errors and examine distribution of the data for all traits studied The sample statistics (skewness and kurtosis values) for all body traits were close ... was performed using an Eppendorf Mastercycler (Hamburg, Germany) with cycling conditions as follows: initial denaturation at 95°C for min, followed by 35 cycles of 94°C for 30 s, 57°C for 90

Ngày tải lên: 27/03/2023, 04:24

... followed for raising the crop Details of landraces used for the present study as given in table Observations recorded Observations were recorded for both qualitative traits as well as quantitative traits ... values for number of seeds per pod and seed yield and minimum for branches per plant Cluster II showed no maximum and minimum values for any of the trait Cluster III showed maximum values for branches ... minimum values for none of the trait Cluster IV showed no maximum and minimum values for any of the trait Cluster V showed maximum value for biological yield per plant and minimum values for none of

Ngày tải lên: 13/01/2020, 23:34

... importance for both culinary and processing purpose, it has been cultivated over large area around the world This crop exhibits rich genetic diversity for various horticultural traits and has a scope for ... their parents for Yields and yield attributing traits taken under consideration and also to identify best heterotic combinations for the same revealed that mean sum of squares for parents and ... significant for all the traits except days to first flowering and number of fruits per cluster indicating presence of heterosis for these characters Significant positive heterosis for plant height

Ngày tải lên: 14/01/2020, 01:20

... The GCA effects for lines and SCA effects for crosses were significant at P≤ 0.01 for all the traits studied The GCA effects for testers were observed to be significant for all the traits The ratio ... exhibited by the cross L4 × T2 for fruit length (83.53%), L5 × T3 for fruit girth (45.26%), L6 × T1 for fruits plant -1 (90.60%), L1 × T2 for fruit weight (95.28%) and L3 × T2 for yield plot-1 (151.34%) ... the cross L6 × T4 for fruit length (74.71%), by L4 × T3 for fruit girth (37.58%), by L6 × T1 for fruits plant -1 (37.86%), by L1 × T2 for fruit weight (51.64%) and by L3 × T2 for yield plot -1

Ngày tải lên: 14/01/2020, 15:37

... model than for model For all the traits, the accuracies for model were slightly higher than those for model although the differences in accuracy between models and were not significant For FDC and ... additive relationship for each trait For all traits, the correlation among full-sibs (k = 1/2) was relatively much Page of 14 higher than for other types of relationship For CC, the correlation ... exponentially For REP, the correlations for k = 1/16, 1/8 and 1/4 were relatively low and there was little increase until a highly increased correlation for k = 1/2 For FDC, the correlations for k =...

Ngày tải lên: 14/08/2014, 13:21

... Supplementary Information LIST OF SUPPLEMENTARY INFORMATION SI 1: Manhattan plot of Genome-Wide Association Study for NBA in LW_2 196 SI 2: Manhattan plot of Genome-Wide Association Study for NBA in ... Genome-Wide Association Study for NBA in LW_2b 196 SI 4: Manhattan plot of Genome-Wide Association Study for NBA in LW_3 197 SI 5: Manhattan plot of Genome-Wide Association Study for NBA in ... Genome-Wide Association Study for NBA in LR_2 197 SI 7: Manhattan plot of Genome-Wide Association Study for NBA in LR_3 198 SI 8: Manhattan plot of Genome-Wide Association Study for NBA in...

Ngày tải lên: 26/11/2015, 10:18

... from these major pieces of the system: Perform Satellite Operations, Perform Launcher Operations, and Perform Ground Operations In keeping with the N2 format, the functions are arranged diagonally ... Focus Research and Development (R&D) Efforts — Finally, if functionality and performance can be identified for future systems, research and development (R&D) efforts can be directed toward developing ... risk performance of the system Since the goal of this book is simply to establish a framework for complex system design, it is beyond the scope of this discussion to elaborate on these Therefore,...

Ngày tải lên: 07/08/2014, 10:20

... Work To Do (04)Cum UD RW Rate (25) SS Task Gen = IF THEN ELSE (Cum SS Tasks > Syn Tasks for SS ∗ Table for SS Tasks wrt Syn FC (Sys Syn Prcv’d Fraction Complete), 0, Number of SS ∗ (Sys Syn Work ... Units: Task Uses: (45)Sys Rqmt Work To Do (16)SR Prcv’d Fraction Complete (17)SR Tasks for Sys Syn (35)Syn Tasks for SS (37)Sys Rqmt Finished (48)Sys Syn Prcv’d Fraction Complete (63) TIME STEP = ... (49)Sys Syn Quality (09) Number of SS = Units: Dimensionless Uses: (25)SS Task Gen (35)Syn Tasks for SS (10) Productivity = 0.5 Units: Task/(Man ∗ Month) Uses: (13)RW Pot Work Rate (21)SS Potential...

Ngày tải lên: 07/08/2014, 10:20

... parameters for reproductive and growth traits in turkeys because 1) reproductive traits are measured on a restricted fraction of the population; 2) there are missing records for some traits, which ... Unfortunately, computational costs prohibited an analysis for all traits simultaneously under this model We suspected, however, that the influence of a maternal genetic effect was greater for traits ... desired to perform multivariate analyses because sequential selection invalidates univariate analyses Unfortunately, the computational burden involved by a multivariate analysis fort traits is far...

Ngày tải lên: 09/08/2014, 18:22