... participate and patients were lost during the follow-up, therefore, a total of 129 patients were finally included in the study This research was carried out in accordance with the Declaration ... Declaration of Helsinki of the World Medical Association (2000) and approved by the Ethics Committee of the participating hospital Informed consent was obtained from each patient or their relatives after ... calculated in the second CT by using the formula 0.5 × a × b × c, where a and b are the largest perpendicular diameters, and c is the number of 1-cm thick sections that contain the lesion All...
Ngày tải lên: 18/06/2014, 19:20
... participate and patients were lost during the follow-up, therefore, a total of 129 patients were finally included in the study This research was carried out in accordance with the Declaration ... Declaration of Helsinki of the World Medical Association (2000) and approved by the Ethics Committee of the participating hospital Informed consent was obtained from each patient or their relatives after ... calculated in the second CT by using the formula 0.5 × a × b × c, where a and b are the largest perpendicular diameters, and c is the number of 1-cm thick sections that contain the lesion All...
Ngày tải lên: 20/06/2014, 03:20
Báo cáo khoa học: "Biological markers of lung injury before and after the institution of positive pressure ventilation in patients with acute lung injury" potx
... hospital The protocol was approved by the Institutional Committee on Human Research, and informed consent was obtained from the patients or the surrogates All patients with ALI admitted to the adult ... post-intubation There was no statistically significant difference among the levels of vWF at the three different time points (p = 0.57) The horizontal line represents the median, the box encompasses the ... time points during the first 24 hours and then on days and after the inclusion in the study APACHE II (acute physiology and chronic health) scores at the time of admission to the intensive care...
Ngày tải lên: 13/08/2014, 03:20
Textbook of Traumatic Brain Injury - part 4 pdf
... determine the mental status of the patient before the agitated or aggressive event, the nature of the precipitant, the physical and social environment in which the behavior occurs, the ways in which the ... psychotherapy for anxiety disorders after TBI Whether anxiety is readily apparent during a patient interview depends on the severity of the patient s deficits, the extent of the anxiety, and the ... of patients Hence, the rate of panic was several times higher than that in the general population Unlike the high rates of anxiety disorders seen in the referral patients in other studies (Fann...
Ngày tải lên: 10/08/2014, 18:20
Báo cáo y học: "Technical Considerations in Decompressive Craniectomy in the Treatment of Traumatic Brain Injury"
... the base backwards along the zygoma but left the fascia base 1-2 cm long for the blood supply Finally, they turned the temporal fascia beneath the temporal muscle and sutured it to the dura They ... to the midpoint between the angles of the dural opening The most significant step involves constructing small supporting pillars on the bilateral sides of the vessels as they pass the edge of the ... meninges The method using temporal fascia is similar to the one introduced by Yu et al.32 They separated the temporal deep fascia from the temporal muscle to the zygomatic arch, and then cut the fascia...
Ngày tải lên: 25/10/2012, 11:40
awareness of deficit after brain injury clinical and theoretical issues jan 1991
... in the bed by a previous patient Sometimes the patients have a tolerant attitude to the repudiated limbs, whereas in other instances they are irritated by their presence and insist on having them ... had made them The authors emphasized that the patients denied any kind of paresthesia, the occurrence of which had been suggested to them by the examiners as a possible explanation of their movements ... form of these disorders may be seen in the feeling of alienness of the limbs contralateral to the brain lesion, explicitly referred to by the patients or inferred by the peculiar nicknames they...
Ngày tải lên: 11/06/2014, 09:45
Báo cáo hóa học: " Effectiveness of a Wii balance board-based system (eBaViR) for balance rehabilitation: a pilot randomized clinical trial in patients with acquired brain injury" ppt
... of the patients, achieving a system that reinforces the motivation of the patients during the rehabilitative process and providing the therapists with objective data of the evolution of the patients ... position the patients are required to maintain their soles on the WBB In sitting position, the patients sit directly on the WBB In the study presented in this paper, the patients play with the system ... rehabilitation [24,25] The system calibrates the maximum excursion of the patients and adapts the range of motion of the exercises to fit their impairment In addition, the therapist can configure the difficulty...
Ngày tải lên: 19/06/2014, 08:20
báo cáo hóa học: "Usability of a virtual reality environment simulating an automated teller machine for assessing and training persons with acquired brain injury" pdf
... rehabilitation hospital For the real ATM practice, the therapist issued the participant an ATM card, a password, and the account number of the target account for the money transfers The assessment criteria ... the system: 1) whenever the user performed incorrectly, the program provided a reminder signal and the user had the opportunity to retry; 2) if the user again answered incorrectly, a cue in the ... varied randomly as set by the system, although the amount used in the intervention was not the same as that used in the pre- and post-testing stages The trainer also taught the participants cash...
Ngày tải lên: 19/06/2014, 08:20
báo cáo hóa học: " Inhibition of the alternative complement activation pathway in traumatic brain injury by a monoclonal anti-factor B antibody: a randomized placebo-controlled study in mice" pot
... on the finding of a significantly increased mortality in the steroid cohort, compared to the placebo control group [15] These data imply that the "pan"-inhibition of the immune response by the ... interfering with the cascade at the central level of the C3 convertases, where the three activation pathways merge (Fig 1) [20,21,25-27] Other approaches were designed to inhibit the main inflammatory ... initiates the formation of the membrane attack complex (MAC, C5b-9) through the terminal complement pathway The MAC forms through the self-association of C5b along with C6 through C9 and leads to the...
Ngày tải lên: 19/06/2014, 22:20
báo cáo hóa học: " Air pollution & the brain: Subchronic diesel exhaust exposure causes neuroinflammation and elevates early markers of neurodegenerative disease" pdf
... increased in the frontal lobe in response to DE only at the highest concentration Interestingly, a synuclein was elevated in the midbrain at only the highest concentration, suggesting that the TNFa ... MIP-1a in the midbrain at the highest concentrations tested This decline in MIP-1a is consistent with a pattern seen in the lung of these same animals, as previously reported [30] Thus, the enhanced ... DE Exposure Modifies the Pro-inflammatory Profile of the Midbrain In an effort to further address the degree of sensitivity of the midbrain to air pollution, we measured the effects of DE inhalation...
Ngày tải lên: 19/06/2014, 22:20
báo cáo hóa học: " Differential aquaporin 4 expression during edema build-up and resolution phases of brain inflammation" doc
... mechanisms include the digestion of serum proteins in the extracellular space by astrocytes [1,7] Therefore, AQP4 may highly facilitate the efflux of water into the blood or the CSF along the osmotic ... participated in the study design and revised the manuscript CM supervised the MR imaging and revised the manuscript KGP participated in the study design, supervised the experiments, contributed to the data ... for by the normalization to the corresponding actin signal by applying the same procedure These molecular markers were compared between the MRI-defined build-up and resolution phases using the Mann-Whitney...
Ngày tải lên: 19/06/2014, 22:20
báo cáo hóa học: " Origin and consequences of brain Toll-like receptor 4 pathway stimulation in an experimental model of depression" docx
... express a large majority of the already discovered 10 TLRs has challenged the way neuroscience explains the role of the immune system in the brain and, as a result, the view of the brain as an immune ... to the inflammatory pathophysiology of the disease [23] Thus, the aims of the present study were to evaluate (1) activation of the TLR-4 pathway in brain after chronic stress exposure, (2) the ... kits following the manufacturer’s instructions (Hycult Biotech, The Netherlands) Plasma LPS was measured using a chromogenic endpoint assay The principle of the test is based on the fact that...
Ngày tải lên: 19/06/2014, 22:20
báo cáo hóa học: " Interleukin-1alpha expression precedes IL-1beta after ischemic brain injury and is localised to areas of focal neuronal loss and penumbral tissues" pdf
... analysis of the study and wrote the manuscript AD carried out the surgeries, contributed to the design and analysis of the study and wrote the manuscript All authors read and approved the final ... confocal slice at the level of the nucleus The fold enrichment of IL-1α and GFP in the nucleus were calculated as follows: Fold enrichment = MFI (nucleus) / MFI (whole cell) The fold enrichment ... microglia-like cells in the ipsilateral hemisphere expressed IL-1α (Figure 2A) IL-1α-positive microglia were present in the cerebral cortex, the piriform cortex, the ventral striatum and the thalamus Immunohistochemistry...
Ngày tải lên: 19/06/2014, 22:20
Báo cáo y học: "Plasmatic B-Type Natriuretic Peptide and C-Reactive Protein in Hyperacute Stroke as Markers of Ct-Evidence of Brain Edema." pptx
... stroke The cause of early death was brain herniation in two patients, and heart failure in the other The mean age of the patients excluded was 84.5 years; two were women and two were man The four ... excluded patients showed very high levels of NT-PBNP (> 400 pmol/L) as it is expected in patients with heart failure The remaining 41patients underwent the complete protocol of the study The mean ... edema, and that these proteins increase in response to edema The second objective of the study is to know whether the values of these proteins change according to clinical outcome PATIENTS AND METHODS...
Ngày tải lên: 08/08/2014, 16:23
Theory of Brain Function quantum mechanics and superstrings - part 4 ppt
... aminoacids, from the 43 = 64 possible combinations of four bases of triplets Then, the messenger RNA (mRNA) is synthesized from the one strand of the DNA double helix, while the other strand of the double ... symmetries, and the very existence of the global states, somehow can trace back their origin to the 2-dimensionality of the world-sheet! In other words, the stringy nature of the modified quantum ... polarity or dipole, with the negative end oriented towards the α-monomer and the positive end towards the β-monomer The dipole character of the dimer originates from the 18 Calcium ions (Ca++...
Ngày tải lên: 10/08/2014, 00:21
Traumatic brain injury and the effects of diazepam, diltiazem, and MK-801 on GABA-A receptor subunit expression in rat hippocampus ppt
... pharmacological responsiveness after TBI These studies, therefore, support the hypotheses that TBI alters the constituent proteins of the GABAAR and that these alterations may be driven by a calcium-mediated ... placed over the exposed dura and sealed with cyanoacrylate adhesive Dental acrylic was applied over the entire device to secure the hub to the skull (leaving the hub accessible) The incision ... comparisons for each subunit The results of this analysis indicated that the 24 hour post-injury time point revealed the greatest changes across the most subunits Therefore, in Study the effects of pre-injury...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: "Regional characterization of energy metabolism in the brain of normal and MPTP-intoxicated mice using new markers of glucose and phosphate transport" doc
... that binds the sodium-dependent phosphate symporter PiT2 has been derived from the RBD of the amphotropic MLV (AMLV) [20,16] Since the gibbon ape leukemia virus (GALV) uses PiT1, the other sodium-dependent ... observed in the cortex in addition to the diffuse staining throughout the striatum (Figure 2B) Noteworthy, the white matter tracts were not stained with any of the three markers In the Substantia ... conditions With HRBD, the GLUT1 ligand, we observed a staining of GLUT1 in the corpus callosum and the basal ganglia apparently weaker than in the cerebellum and in the cortex These results were...
Ngày tải lên: 10/08/2014, 05:21
Textbook of Traumatic Brain Injury - part 1 ppt
... gliding contusion), the corpus callosum, the structures in the walls of the third ventricle, and in the striatum (so-called basal ganglia hematomas) In the majority of these cases, the patients are ... 2–5), and they have a characteristic distribution affecting the poles of the frontal lobes; the inferior aspects of the frontal lobes, including the gyri recti; the cortex above and below the operculum ... 1981) Fractures of the skull may be limited to the vertex, the base of the skull, or may affect both (Table 2–4) The majority of skull fractures are linear, affecting the vault of the skull in 62%...
Ngày tải lên: 10/08/2014, 18:20
Textbook of Traumatic Brain Injury - part 2 potx
... in TBI patients than they are by their physical disabilities (Brooks 1991) Understanding the nature of the stresses on the family and the family’s concerns about the TBI patient enables the clinician ... white arrow), whereas the AC is almost not discernible in the sagittal view of the TBI patient (lower left) Note also the thinness of the corpus callosum in the TBI patient, another reflection of ... toward the lesion In rating PV lesions, the signal intensity involving the WM that “hugs” the ventricle is rated The signal intensity is abnormal in the box on the left that highlights the anterior...
Ngày tải lên: 10/08/2014, 18:20