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5 case control association studies

Báo cáo y học:

Báo cáo y học: "Role of STAT4 polymorphisms in systemic lupus erythematosus in a Japanese population: a case-control association study of the STAT1-STAT4 region" pot

Báo cáo khoa học

... genome-wide association studies [8,9], a study focused on the STAT4 region in Caucasians [10], and replication studies in Colombians [11] and a Japanese population [12] have confirmed the association In ... Patients and healthy controls Patients and controls were recruited at Juntendo University, the University of Tsukuba, and the University of Tokyo All patients and healthy controls were unrelated ... patients and 102 female healthy controls, and allele frequencies were compared between SLE patients and controls A linkage disequilibrium (LD) plot and the results of the association study in the STAT1-STAT4...
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Báo cáo y học:

Báo cáo y học: "TLR7 single-nucleotide polymorphisms in the 3’ untranslated region and intron 2 independently contribute to systemic lupus erythematosus in Japanese women: a case-control association study" ppsx

Báo cáo khoa học

... association of the TLR7 3’ untranslated region (3’ UTR) SNP, rs3853839, was identified Subsequently, the association of rs3853839 was replicated in two independent Chinese and Japanese case -control ... Therefore, male patients and controls were excluded from this study No deviation from the Hardy-Weinberg equilibrium was observed in the controls (P > 0.05) In addition to the association of rs3853839 ... Page of Table Association of TLR7 SNPs with SLE in a Japanese populationa Allelic association Genotype, n (%) Study population rs3853839 G/G G/C C/C 197 (57.3) 125 (36.3) 22 (6.4) Controls 137...
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Báo cáo y học:

Báo cáo y học: "Lack of association of a variable number of aspartic acid residues in the asporin gene with osteoarthritis susceptibility: case-control studies in Spanish Caucasians" potx

Báo cáo khoa học

... patients versus controls, P = 0.9; THR patients versus controls, P = 0.9; and hand OA patients versus controls, P = 0.8), as well as male patients and controls (TKR patients versus controls, P = ... versus controls, P = 0.6; THR patients versus controls, P = 0.5; and hand OA patients versus controls, P = 0.9 Similar results were obtained after stratifying by sex (Table 1) Female patients and controls ... susceptibility in Spanish Caucasians This result reinforces the overall lack of association reported in other studies in Caucasians The association between variation in the number of D residues and OA described...
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Báo cáo y học:

Báo cáo y học: "Association of single-nucleotide polymorphisms in RHOB and TXNDC3 with knee osteoarthritis susceptibility: two case-control studies in East Asian populations and a meta-analysis" docx

Báo cáo khoa học

... (9.7% in control individuals) and Japanese (14.2% in control individuals), which were significantly different from the frequency in the UK control individuals [10] (Table 3) A positive association ... found no association of RHOB and TXNDC3 with knee OA, even though the ethnicity and disease ascertainment were basically the same in the two studies [10] To examine the replication of association ... significant association was detected after stratification by sex Because the results were mixed, we performed the meta-analysis for the four studies (first German study [7] and three replication studies) ...
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Báo cáo y học:

Báo cáo y học: "Association of a single nucleotide polymorphism in growth differentiate factor 5 with congenital dysplasia of the hip: a case-control study" ppt

Báo cáo khoa học

... of CDH To evaluate this possible association, we examined the genetic association of the GDF5 SNP with CDH in people of Han Chinese origin and found a compelling association between GDF5 and CDH ... healthy control subjects (316 females and 306 males) were enrolled at the Physical Examination Center, Drum Tower Hospital, affiliated to the Medical School of Nanjing University, China The controls ... participating institutions, and informed consent was obtained from patients and controls The ages of patients with CDH and controls (mean ± SD) were 21.6 ± 12.4 months (range to 72 months) and 58.1...
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Báo cáo y học:

Báo cáo y học: "Association between occupational exposure to mineral oil and rheumatoid arthritis: results from the Swedish EIRA case–control study" docx

Báo cáo khoa học

... Selection of controls For each potential case a control was randomly selected from the study base with consideration taken for age, gender and residential area The selection of controls was conducted ... continuously updated If a control declined to participate, was not traceable or reported having RA, a new control was selected using the same principles (see also [16]) Controls belonging to cases ... identical way for the case and control groups In total, 1,480 cases and 2,038 controls were identified Of these, 1,419 cases (1,012 women and 407 men) and 1,674 controls (1,188 women and 486 men)...
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Báo cáo y học:

Báo cáo y học: "Association of functional variants of PTPN22 and tp53 in psoriatic arthritis: a case-control study" docx

Báo cáo khoa học

... at onset of psoriasis and PsA, and disease pattern The control individuals (controls) were of similar ethnicity to the patients (cases) Controls for the Newfoundland population were volunteers ... participated in our study as a result of a local campaign seeking population-based controls for genetic studies The Toronto controls were ascertained from the local HLA laboratory DNA bank, which includes ... rationale for this association Alternatively, a false-positive association may have occurred in the Toronto PsA cohort because of population stratification Because the reported RA associations with...
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Báo cáo y học:

Báo cáo y học: "Association of the microsatellite in the 3'''' untranslated region of the CD154 gene with rheumatoid arthritis in females from a Spanish cohort: a case-control study" ppsx

Báo cáo khoa học

... controls, indicating that the 24CAs allele seems to protect from RA when homozygous Association of CD154 with RA is independent of HLADRB1 and HLA-DQB1 Epidemiological studies show a strong association ... cells from patients with RA Materials and methods Patients and controls The study used a case -control design to compare patients and controls A total of 189 patients diagnosed with RA according ... linkage studies have drawn attention to several regions that probably contain candidate genes, namely 1p, 5q, 8p, 12, 13, 18q, 21q and the X chromosome [9-15], for which association studies are...
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Báo cáo y học:

Báo cáo y học: "Association of MICA with rheumatoid arthritis independent of known HLA-DRB1 risk alleles in a family-based and a case control study" pps

Cao đẳng - Đại học

... between results of these studies may be due at least partially to confounding of results by LD with HLA-DRB1 alleles Some studies reported association analyses without controlling for LD of MICA ... these genome-wide studies, association analysis was reported without controlling for LD of MICA alleles with HLA-DRB1 alleles If LD structure in Caucasians in these genome-wide studies was similar ... Table Case -control analysis in German Caucasians (a) All individuals without controlling for LD with HLA-DRB1 Minor allele Allele frequency in cases/controls Total alleles of RA cases/controls...
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Báo cáo y học:

Báo cáo y học: "Association of the T allele of an intronic single nucleotide polymorphism in the colony stimulating factor 1 receptor with Crohn''''s disease: a case-control study" ppt

Báo cáo khoa học

... documented [15-18] Here we report the results of a case -control study of Louisiana patients with Crohn's disease and ethnically similar controls showing increased prevalence of the T allele of ... performed in 111 patients with Crohn's disease and 108 controls (Table 1) Thirty patients with Crohn's disease (27%) but only fourteen controls (13%) had the T allele of the SNP (χ2 = 6.74, p ... Crohn's disease to those of non-Acadian controls (Table 4) In this analysis, patients with Crohn's disease still had significantly higher rates of the T allele than controls The CSF1R protein is expressed...
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báo cáo khoa học:

báo cáo khoa học: " The association of aggressive and chronic periodontitis with systemic manifestations and dental anomalies in a jordanian population: a case control study" pdf

Báo cáo khoa học

... 3.1) a CP vs Controls (Chi-square test)-Anxiety AP vs Controls (Chi-square test) -Anxiety c CP vs AP (Chi-square test) -Anxiety d CP vs Controls (Chi-square test) -Depression e AP vs Controls (Chi-square ... Dental Anomalies in Cases and Controls Dental Anomalies Yes No Total 100 (100) P-valuesa Chi-square test AP Controls No (%) a CP No (%) No (%) CP vs Controls AP vs Controls CP vs AP 15 (15) 85 ... differential distribution of systemic manifestations Systemic Manifestation AP Controls No (%)a No (%)b No (%)c CP vs Control AP vs Control CP vs AP Fatigue 21 (21) 13 (16.0) 15 (18.5) 0.405 0.851 0.229...
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báo cáo khoa học:

báo cáo khoa học:" Lack of association between celiac disease and dental enamel hypoplasia in a case-control study from an Italian central region" pdf

Báo cáo khoa học

... studied and lack of adequate controls Finally, no studies have been performed, in CD patients of a Central Region of Italy (Ancona, Marche, Italy) The aim of this case -control study was to assess ... has been reported in other studies [17,43-48]; our data are in agreement with other studies performed in Italy (Table 1) and the high frequency of enamel defect found in controls, as well as its ... observed in 13/50 (26%) subjects with CD and in 8/50 (16%) controls, with a ratio male-female of 1:2 for the celiac group and 2:1 for control group (p > 0.2; OR = 1.8446; 95% CI = 0.6886: 4.9414)...
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Báo cáo y học:

Báo cáo y học: "Association between occupation and knee and hip replacement due to osteoarthritis: a case-control study" doc

Báo cáo khoa học

... questionnaire, leaving 490 men and 592 women as our controls The cases and controls were thus of similar age and from the same genetic pool Cases and controls signed an informed consent and answered ... example, farmers or fishermen also in the control sample The association with hip osteoarthritis amongst male farmers has been established in several studies [7-9,13,22,23], including one prospective ... http://arthritis-research.com/content/12/3/R102 son of the risk for hip and knee OA Most studies have been cross-sectional, but recently results from longitudinal studies have been published, strengthening the causality of...
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Báo cáo y học:

Báo cáo y học: "Association of the D repeat polymorphism in the ASPN gene with developmental dysplasia of the hip: a case-control study in Han Chinese" potx

Báo cáo khoa học

... than the common allele, D13 [15] This association was replicated in different populations and confirmed by meta-analysis although some studies denied this association [23-29] This polymorphism ... pathogenesis of DDH To evaluate the possible association, we conducted a casecontrol study on ASPN with DDH in the Chinese Han population and found a compelling association between ASPN and DDH Materials ... DDH with a case -control association study in Chinese Han population D14 was identified as the risk allele; otherwise the common allele, D13, seemed to be a protective allele Association was detected...
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Báo cáo y học:

Báo cáo y học: "Attributable mortality of Acinetobacter baumannii infections in critically ill patients: a systematic review of matched cohort and case-control studies" doc

Báo cáo khoa học

... with matched controls Reference Site of infection; patients and setting Cases Controls Matching of controls to cases Colonization or infection Mortality Length of ICU stay (days) Cases Controls p ... baumannii infection in these studies ranged from 7.8% to 23% In addition, three studies reported data about the mortality of cases and controls in the ICU [11,14,21] In all three studies mortality in ... case -control and cohort studies in our attempt to provide data from comparative studies with analytical methodology However, it should be noted that different matching criteria were used in the studies...
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THE VALUE OF RE USING PRIOR NESTED CASE CONTROL DATA IN NEW STUDIES WITH DIFFERENT OUTCOME

THE VALUE OF RE USING PRIOR NESTED CASE CONTROL DATA IN NEW STUDIES WITH DIFFERENT OUTCOME

Cao đẳng - Đại học

... function of number of controls per case, with dashed lines representing studies with new cases and prior data, and solid lines representing studies with newly sampled controls for studies with (a) ... functions 19 3.2 Nested case -control studies For each simulated cohort, we conducted two nested case -control studies and allowed the length of the follow-up period in the two studies to vary in order ... existing NCC data in many areas, such as Genome-wide association studies (GWAS) in genetic epidemiology as well as biomarker studies GWAS and biomarker studies are used to identify common genetic factors...
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 Báo cáo y học:

Báo cáo y học: "Comparative study of control selection in a national population -based case-control study: Estimating risk of smoking on cancer deaths in Chinese men"

Y học thưởng thức

... case -control study to assess the validation of the novel control selection design by comparing the consistency between the new design and a routine control selection design in a large case -control ... husband and wife in control group in terms of tobacco use; (3) the causes of death in control group were unrelated to tobacco exposure Thus two separate population-based case -control studies were formed ... total of 130,079 cases and 152,579 controls (103,248 in control group 1; 49,331 in control group 2) in our study The basic characteristics of the cases and controls, and relative risk of smoking-related...
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Breast cancer risk in relation to occupations with exposure to carcinogens and endocrine disruptors: a Canadian case–control study pptx

Breast cancer risk in relation to occupations with exposure to carcinogens and endocrine disruptors: a Canadian case–control study pptx

Sức khỏe giới tính

... research on associated breast cancer risk A weak association was found for breast cancer risk and soluble metalworking fluids [18] Several studies have found associations between PAH exposure and breast ... the numbers of industrial workers developing cancer [25] Two exploratory breast cancer case control studies were undertaken by a multidisciplinary team of occupational and environmental researchers ... and counts of controls and cases by minor sector of longest duration Major sector Non-plastics light manufacturing Cases 1006 Agriculture/plants 23 37 Agriculture/animals Farming Controls 1146...
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Occupation and Breast Cancer: A Canadian Case–Control Study docx

Occupation and Breast Cancer: A Canadian Case–Control Study docx

Sức khỏe giới tính

... cohort, and case-controls studies. 38 Of 10 administrative and cohort studies, found a positive association with breast cancer39−46 while did not.47,48 Among six case control studies3 1,49–53 there ... is generally noted in several studies that examined breast cancer among registered hospital nurses but these studies shared methodological limitations; most did not control for known or suspected ... NEW YORK ACADEMY OF SCIENCES Study.” The controls were approximately matched by age and by geographical area Five hundred ninety-nine eligible community controls participated out of 1146 contacted...
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Associated factors for treatment delay in pulmonary tuberculosis in HIV-infected individuals: a nested case-control study docx

Associated factors for treatment delay in pulmonary tuberculosis in HIV-infected individuals: a nested case-control study docx

Sức khỏe giới tính

... delay Chest pain is one of the symptoms associated with TB in some studies [18,19,33], but no studies have been encountered with an association of diagnostic and treatment delay of TB related to ... affect comparability between studies Finnie et al [22] reported that HIV and its relation with a delay in diagnosing and treating TB was assessed in only 20% of the studies selected for their systematic ... initiated [11] Several studies have addressed the problem of delayed diagnosis and treatment for TB, but only a few with HIV-infected individuals [5,8,12-19] Of these reports, only the studies by Kramer...
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