... Development of an HSV-tk transgenic mouse model Fig Comparison of serum parameters of TK5-F1 mice with the wild-type mice (n ¼ 3) Results are expressed as mean ± SD of three mice After 21 days of GCV ... survival rate of Hep-G2 cells was reduced significantly after transfection with HSV-tk (Fig 1B) Detection of inserted transgene and monitoring of the pedigree of mouse family TK5 by PCR A total of 182 ... 2005 FEBS Y Zhang et al Development of an HSV-tk transgenic mouse model A B Fig Analysis of integration of transgene in mouse family TK5 (A) PCR analysis of the transgenic mice in TK5-F1 1, Hep-G2...
Ngày tải lên: 30/03/2014, 16:20
... can of the total transferred power, and the impact of in (26), be neglected Substituting the model of the dc link is deduced as follows: (29) The model of DFIG in (21) is a nonlinear dynamic model ... components of the stator flux of a DFIG in a field-oriented frame of can be obtained from (15) and (16) as reference with and can be readily obtained from the solution of (37) for B Model of the Grid-Side ... derivatives of assumption, currents will be proportional to the derivatives of power based on (2) and (5) B Model of DFIG Using Instantaneous Power Components The voltage and flux equations of a doubly...
Ngày tải lên: 27/06/2014, 16:04
Acoustic behaviors of polymer microspheres with tailored chain or matrix structures
... Modification of Porous Copolymer Networks 33 3.3.1 Preparation of Porous Crosslinked Microspheres 33 3.3.2 Metallization of Porous Copolymer Microspheres 34 3.3.3 Preparation of Semi-IPN Composed of Poly(ethyl ... rotations and creeping of polymer segments or pendant groups, tiny amounts of heat are generated due to the frictions of these motions or change of potential energy in the polymer phase Polymer segments ... properties of polymers to damp sound waves has been a technology related to the protection of human being from the pollution of noise The theoretical basis and recent developments of this type of functional...
Ngày tải lên: 26/09/2015, 10:59
Báo cáo y học: "MALDI-TOF MS Combined With Magnetic Beads for Detecting Serum Protein Biomarkers and Establishment of Boosting Decision Tree Model for Diagnosis of Colorectal Cancer"
... based on a first pass of signal-noise ratio of and a minimum peak threshold of 20% of all spectra This process was completed with a second pass of peak selection at 0.2% of the mass window, and ... calculated as the ratio of the 42 number of correctly classified diseased samples to the total number of diseased samples Specificity was calculated as the ratio of the number of negative samples ... Diagnostic Model The decision tree could differentiate samples of CRC and healthy controls Here, we used the biomarker wizard function of the ProteinChip software to identify clusters of peaks...
Ngày tải lên: 25/10/2012, 11:18
Báo cáo y học: "Parvovirus B19 Nonstructural Protein-Induced Damage of Cellular DNA and Resultant Apoptosis"
... indicating that NS1 damages cellular DNA, and that this damage leads to apoptosis Upon detection of DNA damage, DNA damage response proteins inhibit the cell cycle and are capable of inducing apoptosis ... 5-aminoisoquinolinone The importance of DNA damage to NS1-induced apoptosis is shown by the abrogation of apoptosis in 93 the presence of inhibitors of DNA damage recognition enzymes Both the ... result in apoptosis if the damage is severe Damage of chromosomal DNA by parvoviral proteins has not been directly demonstrated, except in the case of specific integration of AAV We present here...
Ngày tải lên: 25/10/2012, 11:18
Appendix 1 - Outline of Density Matrix Analysis
... time dependence of pj is omitted, the time variation of can be written as X ðtÞ ¼ UðtÞj j ð0Þipj h j ð0ÞjUðtÞy ¼ UðtÞð0ÞUðtÞy ðA1:6Þ j Then, calculation of the time derivative of results in ... calculate the value of the macroscopic observable hAi without knowing j ji and pj, provided that is obtained A1.2 EQUATION OF MOTION FOR THE DENSITY OPERATOR The time variation of a state j ji ... equation to calculate (t), followed by calculation of hAi by Eq (A1.4), clarifies the behavior of the whole system concerning the observation of the quantity A The above description is made in...
Ngày tải lên: 17/10/2013, 13:15
06 ON TAYLOR MODEL BASED INTEGRATION OF ODES
... by a Taylor model, or • when operations between Taylor models are executed Example 2.4 Addition of two univariate floating-point Taylor models For simplicity, we use Taylor models of order and ... Taylor models U and V instead of a Taylor model vector The symbolic variables are denoted by a and b (instead of the vector x) Example 5.1 Absorption of the interval part into the symbolic part of ... terms of order higher than n (which in applications are usually small) are processed according to the rules of interval arithmetic Example 2.2 Multiplication of two univariate Taylor models of order...
Ngày tải lên: 12/01/2014, 21:46
10 on taylor model based integration of ODEs neuer 2006
... Taylor Models Verified Integration of ODEs Taylor Model Methods for ODEs Verified Integration of Linear ODEs Outline Interval Arithmetic and Taylor Models Verified Integration of ODEs Taylor Model ... On Taylor Model Based Integration of ODEs Interval Arithmetic and Taylor Models Verified Integration of ODEs Taylor Model Methods for ODEs Verified Integration of Linear ODEs Quadratic Model Problem ... On Taylor Model Based Integration of ODEs Interval Arithmetic and Taylor Models Verified Integration of ODEs Taylor Model Methods for ODEs Verified Integration of Linear ODEs Quadratic Model Problem...
Ngày tải lên: 12/01/2014, 21:47
Tài liệu Báo cáo khoa học: Solution structure of the matrix attachment region-binding domain of chicken MeCP2 ppt
... were analyzed by comparison of 1H-15N HSQC spectra of free MAR-BD with those of MAR-BD titrated with the 15mer oligonucleotide duplex at molar ratios of : 1.2 and of : 2.4 Experimental procedures ... involvement of residues located in the unfolded parts of unbound MAR-BD is hard to predict, because a considerable fraction of the NMR signals of those regions could not be assigned in the spectra of ... contacting the DNA backbone The solution structure of the MBD of MBD1 shows high similarity to that of MeCP2 except for the C-terminus [18] At the C-terminus of the MBD, MeCP2 exhibits a one-turn helix,...
Ngày tải lên: 21/02/2014, 00:20
Báo cáo khoa học: Reduction of a biochemical model with preservation of its basic dynamic properties doc
... parameters 4864 20D model lumping & fitting 20L8D model elimination of variables elimination of variables 20E6D model 20LE3D model Fig Overview of the model reductions The 20D model is the model described ... constrained 20L8D model Table S1 Parameters of the 20L8D model Table S2 Parameters of the 20E6D model Table S3 Parameters of the 20LE3D model Table S4 Unstable stationary state of the 20L8D model provided ... reduced model of lowest dimension Model properties We judge the effects of the model reductions by comparing the dynamic and biochemical properties of the original 20D model to those of the three...
Ngày tải lên: 07/03/2014, 11:20
Báo cáo khoa học: Molecular cloning of the Matrix Gla Protein gene from Xenopus laevis Functional analysis of the promoter identifies a calcium sensitive region required for basal activity doc
... coding sequence (Fig 2) Analysis of the phase of each of the xMGP introns located within the coding region revealed that introns and are of phase I while intron is of phase II [29] The same phases ... regulators of xMGP transcription is the topic of ongoing investigations ể FEBS 2002 Functional analysis of Xenopus MGP gene promoter (Eur J Biochem 269) 1955 The understanding of the ne tuning of MGP ... identied 5Â end of the xMGP cDNA [4] The lower group of bands, identied as site ễBế in Fig 4, probably corresponds to a premature arrest of the reverse transcriptase due to the presence of an inverted...
Ngày tải lên: 08/03/2014, 10:20
Báo cáo khoa học: Membrane type-1 matrix metalloprotease-independent activation of pro-matrix metalloprotease-2 by proprotein convertases docx
... 6275 Activation of pro -matrix metalloprotease-2 by proprotein convertases A C B Fig PC-dependent processing of pro-MMP-2 (A) Effect of various inhibitors on the propeptide processing of MMP-2 in ... B.-H Koo et al Activation of pro -matrix metalloprotease-2 by proprotein convertases A C B Fig Cellular location of PC processing of pro-MMP-2 (A) Protease activities of PCs in conditioned medium ... et al Activation of pro -matrix metalloprotease-2 by proprotein convertases A A B B Fig Regulation of excessive PC processing of pro-MMP-2 by Pro100 residue (A) PC processing of pro-MMP-2 and...
Ngày tải lên: 16/03/2014, 00:20
Báo cáo khoa học: Characterization of Trypanosoma brucei PEX14 and its role in the import of glycosomal matrix proteins pptx
... the level of PEX14 mRNA in these cells was significantly lower (not shown) In order to determine the influence of the reduction of the expression of TbPEX14 on the import of glycosomal matrix proteins, ... component of the docking complex and a point of convergence of the PEX5- and PEX7-dependent import pathways [15–17] The N-terminal part of PEX14 interacts with the repeated motifs WXXXF/Y of PEX5 ... domain of the polypeptide of each of these organisms is followed by a stretch of hydrophobic amino acids that is presumably involved in the protein’s anchoring to the membrane Also in PEX14 of T...
Ngày tải lên: 23/03/2014, 17:21
Báo cáo Y học: A model for recognition of polychlorinated dibenzo-p-dioxins by the aryl hydrocarbon receptor docx
... the central part of the ligand and of electrophilic sites at the sides of the principal molecular axis are both explained by our model CONCLUSIONS Given the limitations in today's modelling and ... helix, which shows a Ê translational displacement of A that allows the accommodation of the heme cofactor (Fig 1C) [12] The hydrophobic core of the three domains is generally well conserved, ... transducing regions of PYP and FixL are thus located at the opposite ends of the Fig Schematic representation of the HERG (A), PYP (B), and FixL (C) PAS domains displaying the high degree of structural...
Ngày tải lên: 24/03/2014, 00:21
assessing damage of flood by using alos data in thua thien - hue province - vietnam
... calculation of flooded time is based on information from the People Commutee of Thua Thien - Hue Province 4.4 Damage level Assessment of damage level of flood needs based on two groups of basic ... different levels in order to assess damage of landuse/cover types based on scale of DEM 4.3 Flooded time The flooded time is one of important parameters to evaluate damage of landuse/cover types The big ... method of detecting and assessing damages due to flood by using ALOS satellite data is developed - Map of landuse/cover in 2008, map of distribution of flooding areas at October nd 2007 and a DEM of...
Ngày tải lên: 26/03/2014, 14:07
APPENDIX A – THE AUDIT RISK MODEL INDEPENDENT AUDITS OF FINANCIAL STATEMENTS pdf
... concept of materiality enters into the risk assessment process, and the selection of the nature, timing and extent of the audit procedures is an integral part of the model Furthermore, the model ... model contains and does not contain are worthy of discussion First, the model subsumes the concept of “materiality.” Auditors not have to concern themselves with every possible misstatement of ... auditor might send a larger number of accounts receivable confirmations at year end The model requires an assessment of the risk of fraud (intentional misstatements of financial statements) in every...
Ngày tải lên: 29/03/2014, 18:20
Báo cáo khoa học: "A Joint Model for Discovery of Aspects in Utterances" potx
... αD Nud + αA d The Nu is the number of occurrences of domain topic d in utterance u, Na|ud is the number of occurrences of act a given d in u During sampling of a Domain p(Sujd = k Nujd + β k N(.) ... (acoustic modeling engine) to train our models Thus, our dataset contains 18084 NL utterances, 5034 of which are used k The Nujd is the number of times segment wuj is for measuring the performance of ... topic model for credit attribution in multi-labeled corpora Proc EMNLP J Reisinger and M Pasca 2009 Latent variable models ¸ of concept-attribute attachement Proc of the Annual Meeting of the...
Ngày tải lên: 30/03/2014, 17:20
principles of polymer engineering
... Eyring's model of the flow of solids 5.2.3 Yielding under multiaxial stresses 5.3 Crazing 5.4 Fracture mechanics 5.4.1 Measurement and application of KIc 5.5 Fracture properties of polymers Problems ... Dynamic properties 4.3 Theory of linear viscoelasticity 4.3.1 The Zener model 4.3.2 Distribution of relaxation times 4.3.3 Origin of temperature dependence 4.4 Polymer selection: stiffness 4.4.1 ... past 0.2 Engineering plastics Structure of the molecule Introduction 1.2 Addition polymers 1.3 Condensation polymers 1.4 Copolymers 1.5 Cross-linked polymers 1.6 Molecular symmetry and the...
Ngày tải lên: 02/04/2014, 16:29
principles of polymer processing
... rate of change of P of the system, at the instant it coincides with the control volume, is the sum of two terms: the rate of change of P within the control volume, and the net rate of flow of P ... which is very useful in modeling of polymer processing operations, and discuss the broad principles of mathematical modeling of complex processes See R Feynman, The Character of Physical Law, MIT ... developments that have led to today’s diverse arsenal of sophisticated polymer processing machines and methods of processing polymers and polymer systems of ever-increasing complexity and variety As discussed...
Ngày tải lên: 02/04/2014, 16:29