4 other causes of heart failure symptoms in patients with normal ef

... strongly associated with the manifestations of NPSLE We found elevated levels of the antibody-inducing cytokine APRIL in the CNS of NPSLE patients compared with SLE patients without CNS involvement Elevated ... and BAFF in CSF of systemic lupus erythematosus (SLE) patients, (d) APRIL and BAFF in serum of SLE patients, (e) IL-6 and APRIL in CSF of SLE patients, and (f) IL-6 and BAFF in CSF of SLE patients ... levels of APRIL and BAFF in the CSF of SLE patients APRIL was augmented in NPSLE patients compared with SLE patients without CNS involvement Potential implications of our findings could be that APRIL...

Ngày tải lên: 09/08/2014, 10:23

... understanding of the specific role of such pain symptoms in worsening the functioning in patients with GAD The presence of PPS is associated with a statistically and clinically significant impairment in ... of comorbid MDD in patients with GAD was approximately 40% and the prevalence of GAD in primary care patients was around 8% In order to obtain a final sample size of 249 patients in the comorbid ... estimated in order to achieve a power of 88% when comparing differences between a proportion of patients with PPS in the GAD+MDD- group of 44% [30] and a proportion of patients with PPS in the control...

Ngày tải lên: 11/08/2014, 15:22

... were in line with those reported from the observed case analysis The efficacy of asenapine in treating depressive symptoms is supported by in vitro and in vivo preclinical findings Asenapine has ... reported in patients with bipolar I or II depression receiving quetiapine or in patients with bipolar I depression receiving olanzapine/ fluoxetine [21-23] They are also within the range of values ... categories, with reductions in depressive symptoms being more robust in patients with baseline MADRS total scores ≥20 than in those with baseline CGI-BP-D severity scores of ≥4 or those experiencing...

Ngày tải lên: 11/08/2014, 15:22

... demonstrating internal validity Within each category of symptoms, multiple symptoms were associated with any PFT abnormality but no single symptom resulted in AUC > 0.63, indicating that individual ... calculated, including C-reactive protein [37] Joints were examined for swelling and tenderness by a single trained examiner The extent of radiographic joint damage was assessed at the baseline visit ... 10 of 11 Additional file Probability of abnormal PFTs with varying combinations of predictors Word document containing a graphical representation of the range of probabilities associated with...

Ngày tải lên: 12/08/2014, 14:21

... of 2004 were included The decision to intubate was left to the discretion of the treating intensivist ALI was defined according to the American-European Consensus Conference definition [13] Sepsis ... defined according to the American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference definition [14] Patients who had 'do not resuscitate/do not intubate' preferences ... and two patients who refused research authorization, 54 patients were included in the analysis The principal diagnosis was pneumonia in 34 (63%) patients, followed by vasculitis in (15%) patients, ...

Ngày tải lên: 12/08/2014, 23:23

... (12 of 17) of the formalin-fixed samples, and 38% (10 of 26) of the Bouin's fixed tissues Thus, the VHL gene was entirely sequenced (ie 100% of the coding sequence analysed) for a total of 26 ... ppm.years with peaks) other chlorinated solvents, cutting oils, lead, ionizing radiations, asbestos and welding fumes 20 pack-years < 25 of missense mutations is different in the two groups with 68% of ... support the hypothesis of the involvement of environmental factors in the aetiology of sporadic RCC [17-19] Brüning et al studied the RCC incidence in individuals with former prolonged and high-level...

Ngày tải lên: 20/06/2014, 00:20

... presence of floor (an excess of minimum scores) and ceiling (an excess of maximum scores) effects were examined by calculating the distribution of domain scores at SIV-1 Floor or ceiling effects indicate ... the refined version because it was clearly understood by patients during cognitive debriefing The two domains were renamed Injection-site reactions and Ease of use in the refined version Finally, ... self-injection domain demonstrated sensitivity in discriminating between patients with lower and higher scores in the PRE module Selfconfidence and Feelings about injections domains or in any of...

Ngày tải lên: 20/06/2014, 15:20

... compared the magnitude of within-patient change in pain severity with corresponding changes in function and health status The cutpoint analysis indicated that pain severity ratings of 1-3, 4-6, and ... (Figure 1) A 2-point decrease in pain was associated with an estimated 1.5-point decrease in pain interference on daily function or PII (Figure 2) A 2point decrease in pain was associated with an estimated ... other PROs assessed at baseline and end of double-blind treatment at week These PROs included the following: the Pain Interference Index (PII) from the modified Brief Pain Inventory - short form (mBPI-sf)...

Ngày tải lên: 20/06/2014, 15:20

... verified by studies performed with patients with respiratory failure, with depression being observed in 30% of patients with moderate failure and in 50% in patients with severe obstructive pulmonary ... mood disorder in patients with chronic disease is 8.9% to 12.9%, with a 6-month prevalence of 5.8% to 9.4% [3,4] According to findings from worldwide research, 20% of patients with somatic disease ... patients with TB had the lowest depression scores Anxiety was higher in patients with COPD compared to patients with TB Patients with COPD were older and had more years of illness compared to those with...

Ngày tải lên: 08/08/2014, 23:20

... However, there is smaller bank of conflicting data demonstrating that GC use in RA paradoxically restores glucose handling to normal whilst also inducing hyperinsulinism [68] In the present RA population, ... suppressing the impact of inflammation on the metabolic syndrome may outweigh the harmful effects of GCs For example, in RA, many components of the lipid profile are suppressed by the ongoing inflammatory ... almost two thirds of patients with RA have features of rheumatoid cachexia [46], and a recent study has demonstrated the need for redefining the body mass index in RA to take into account these...

Ngày tải lên: 09/08/2014, 01:22

... of a trial of interferon-β-1a in patients with rheumatoid arthritisa Response, according to ACR criteria, of subjects in a trial of β interferon-β-1a in patients with rheumatoid arthritis Adverse ... immunomodulation of RA and potentially lead to a reduction in symptoms and increase in function in patients with RA The present study was designed to assess the effects of the use of IFN-β-1a for ... recruitment, including the commercial availability of other biologic response modifiers, patients concerns regarding self-administration of an intramuscular injection, and perception on the part of patients...

Ngày tải lên: 09/08/2014, 01:23

... carrying groceries; climbing several flights of stairs; climbing one flight of stairs; bending, kneeling or stooping; walking more than a mile; walking several blocks; walking one block; and bathing ... bed, lifting a cup, walking, bathing, bending, turning faucets, and getting in and out of a car), on a scale ranging from to (without difficulty, with some difficulty, with much difficulty, and ... or research nurse, trained in joint examination techniques, assessed 48 joints in each patient for the presence or absence of tenderness or pain on motion, swelling, or deformity, as described...

Ngày tải lên: 09/08/2014, 01:23

... Cystadenocarcinoma of the appendix: an incidental imaging finding in a patient with adenocarcinomas of the ascending and the sigmoid colon BMC Gastroenterol 2003, 3:30 Lyda MH, Noffsinger A, Belli ... appendices with neoplasms did not appear abnormal in the preoperative imaging and during the intraoperative examination However, the case of metastases in the mesoappendix from a descending colon ... these authors suggested performing incidental appendectomy in all CRC patients Meanwhile, Albright et al determined the cost-effectiveness of interval appendectomy in patients who undergo curative...

Ngày tải lên: 09/08/2014, 04:21

... a cut- Therapy with infliximab has definite long-term clinical efficacy and safety in patients with AS Patients who discontinue therapy are likely to have a clinical relapse within several weeks ... 41 were again receiving infliximab in patients with AS Several important observations were made First, we found that discontinuation of long-term therapy with infliximab in patients with AS leads ... treatment Of the 42 patients, 10 had to be retreated within 12 weeks after discontinuation of infliximab infusions, 37 within 24 weeks, and 38 within 36 weeks By week 48, of the 42 patients had not...

Ngày tải lên: 09/08/2014, 06:22

Ngày tải lên: 09/08/2014, 06:23

... expression of ICOS in these patients with SLE We examined expression of ICOS in three patients with active SLE before and after treatment with highdose prednisolone In these three cases, percentages of ... one with inactive SLE were receiving maintenance doses of corticosteroid whereas 13 out of the 16 patients with active SLE considered in the analysis of ICOS expression were examined before institution ... cell line CHO-K1 were stained with biotinylated JTA009 (thick line), biotinylated SA12 (broken line), or biotinylated JMAb23 (human IgG2; thin line) and streptavidin-FITC, and then analyzed using...

Ngày tải lên: 09/08/2014, 07:20

... reduction in mobility achieved with the use respiratory gating, derived from calculating the displacement of the GTVgating within GTVall phases, and (iii) residual GTV mobility within gating windows, ... respiration-induced mobility), plus an isotropic margin of 1.0 cm for microscopic extension and set-up inaccuracies; (iii) PTVgating, consisting of the volume encompassing 3– GTVs in the gating window, ... the efficiency of treatment delivery, and a total of phases were selected in patients as review of the 4DCT movies suggested limited mobility of the primary tumor within in these 'gates' Deriving...

Ngày tải lên: 09/08/2014, 10:20

... reduction of adhesive properties of CPCs One could logically consider the in vitro binding of CPCs to fibronectin as a reflection of the capacity of CPCs to bind to damaged endothelium in vivo ... proteolytic domain Caspase 8L binds to the Fas-associating protein with death domain (FADD) and blocks the binding of caspase to FADD by competiive inhibition [39] Indeed, in hematopoietic stem cells ... During maturation of these cells, the expression of CD133 is lost The combined expression of CD34 and CD133, therefore, defines a population of (immature) circulating progenitor cells Because of...

Ngày tải lên: 09/08/2014, 10:20

... However, there is smaller bank of conflicting data demonstrating that GC use in RA paradoxically restores glucose handling to normal whilst also inducing hyperinsulinism [68] In the present RA population, ... suppressing the impact of inflammation on the metabolic syndrome may outweigh the harmful effects of GCs For example, in RA, many components of the lipid profile are suppressed by the ongoing inflammatory ... almost two thirds of patients with RA have features of rheumatoid cachexia [46], and a recent study has demonstrated the need for redefining the body mass index in RA to take into account these...

Ngày tải lên: 09/08/2014, 13:22

... bioavailability of vitamin D in obesity Am J Clin Nutr 2000, 72:690-693 Page of 38 Bischoff-Ferrari H: Health effects of vitamin D Dermatol Ther 2010, 23:23-30 39 Glare PA: Pain in patients with HIV infection: ... prevalence of vitamin D deficiency of 62% in dark-skinned individuals in a cross-sectional study of HIV-positive individuals In their study, patients on an NNRTI-based therapy had lower vitamin D levels ... was defined as urea and creatinine twofold above the normal reference values “Severe liver disease” was defined as a patient having both elevated alanine aminotransferase and aspartate aminotransferase...

Ngày tải lên: 10/08/2014, 05:21