4 mesenchymal stem cells in cord blood
Báo cáo khoa học: "Transplantation of canine umbilical cord blood-derived mesenchymal stem cells in experimentally induced spinal cord injured dogs" pot
Ngày tải lên :
07/08/2014, 23:22
... ilumits cinegotim cificepsnon ro ralullec yb decudni noitarefilorp etycohpmyl-T sserppus sllec lamorts worram enob namuH MA innaiG ,S itnasirG ,P iccuettaM ,DP inognoL ,M isenaliM ,M ingaM ,C ... latipsoH gnihcaeT lacideM yranireteV ytisrevinU lanoitaN luoeS ta god lergnom gk 85 a fo noitces nairaseaC eht gnirud deniatbo saw BCU :noitcelloc lleC sCSM-BCU eninac fo snoitaraperP dehsilbatse saw ... yliad semit eerht tsael ta demrofrep saw noisserpxe reddalb launam ,dedeen fi dna ,tinu erac evisnetni na ni derotinom erew sgod eht ,noitarepo eht retfA h 21 retfa devomer neht dna ,erutus epyt...
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Báo cáo y học: "Therapeutic potential of human umbilical cord mesenchymal stem cells in the treatment of rheumatoid arthritis" pps
Ngày tải lên :
12/08/2014, 15:22
... self-antigen-reactive T cells in vivo [38] The upregulation of IL-10 is in line with the induction of Tregs in vitro and in vivo in our study Moreover, in our experiments we did not find UC-MSCs in the joint of ... UC-MSCs, indicating that UC-MSCs might be potentially important in the inhibition of bone erosion in RA T cells are believed to play a critical role in orchestrating the inflammatory response in RA ... enzyme-linked immunosorbent assay; FLS: fibroblast-like synoviocyte; FOXP3: forkhead box P3; IL-10: interleukin 10; IDO: indoleamine 2,3-dioxygenase; INDO: indomethacin; L-NAME: N-nitro-Larginine...
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Báo cáo y học: "Mesenchymal stem cells in arthritic disease" pot
Ngày tải lên :
09/08/2014, 13:22
... delivered via either adenoviral infection or osmotic pumps in inhibiting bleomycin-induced increases in TNF-α, IL-1α, and trafficking of lymphocytes and neutrophils into the lung [56] These successful ... produce inflammatory mediators, including IL-1, TNF-α, IFN-γ, and IL-6, and secrete MMPs, leading to the systemic inflammation that eventually results in joint destruction [78,80] Pharmacological interventions ... recovery after coinfusion of autologous -blood stem cells and cultureexpanded marrow mesenchymal stem cells in advanced breast cancer patients receiving high-dose chemotherapy J Clin Oncol 2000,...
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báo cáo khoa học: " Efficacy of Mesenchymal Stem Cells in Suppression of Hepatocarcinorigenesis in Rats: Possible Role of Wnt Signaling" doc
Ngày tải lên :
10/08/2014, 10:21
... that link MSCs to the targeted inhibition of tumor cells Despite their distinct origins, stem cells and tumor cells share many characteristics[15,16] In particular, they have similar signaling ... signaling target genes:cyclin D, PCNA, survivin, b-catenin Methods Ninety albino female rats inbred strain (Cux1: HEL1) of matched age and weight (6 months-1 year & 120-150 gm) were included in ... tissues, including the liver Microvesicles are mediators of cell reprogramming Following injury, tissues release chemokines attracting circulating BMDC, and can produce microvesicles including RNA,...
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Báo cáo y học: " Mesenchymal stem cells in autoimmune diseases: hype or hope" ppt
Ngày tải lên :
12/08/2014, 14:21
... rejection in a nonmyeloablative setting Blood 2006, 108:2114-2120 Boissel L, Tuncer HH, Betancur M, Wolfberg A, Klingemann H: Umbilical cord mesenchymal stem cells increase expansion of cord blood ... mesenchymal stromal cells Blood 2007, 110:3499-3506 Nauta AJ, Westerhuis G, Kruisselbrink AB, Lurvink EG, Willemze R, Fibbe WE: Donor-derived mesenchymal stem cells are immunogenic in an allogeneic ... [1] Given the apparent difficulties in recapitulating the in vitro effects in vivo, however, researchers should be cautioned and should remain critical concerning the use of MSCs for the treatment...
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Báo cáo y học: " Curcumin mediated suppression of nuclear factor-κB promotes chondrogenic differentiation of mesenchymal stem cells in a high-density co-culture microenvironment" pdf
Ngày tải lên :
12/08/2014, 14:22
... through the inhibition of IκB kinase Page of 15 [13,18] There is increasing interest in curcumin as a therapeutic option for OA and RA, with evidence that curcumin inhibits the IL-1β-induced activation ... containing viable, rounded cells that were embedded in a cartilage specific matrix In these Page of 15 cultures, a four-hour curcumin pre-treatment (d) was as effective in inhibiting IL-1β induced ... signalling molecules such as β1-Integrin Similar observations have been made in chondrocytes [15] Interestingly, integrins have already been shown in several tissues to be able to mediate curcumin...
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Applying macromolecular crowding to promote the expansion and adipogenic differentiation of human mesenchymal stem cells in vitro; an effect of matrix reciprocity
Ngày tải lên :
11/09/2015, 09:16
... 2001;Function and interactions of integrins Cell Tissue Res (3):285-298 41 Mould AP, Askari JA, Aota SI, et al 1997;Defining the topology of integrin alpha5beta1-fibronectin interactions using inhibitory ... colony-forming cell and the haemopoietic stem cell Blood Cells (12):7-25 32 Moore KA, Lemischka IR 2006 ;Stem cells and their niches Science (5769):1880-1885 33 Lemischka IR, Moore KA 2003 ;Stem cells: interactive ... 2007 ;In vitro enhancement of collagen matrix formation and crosslinking for applications in tissue engineering: a preliminary study Tissue Eng (2):385391 37 Qian L, Saltzman WM 2004;Improving...
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Báo cáo khoa học: "In vitro neuronal and osteogenic differentiation of mesenchymal stem cells from human umbilical cord blood" ppt
Ngày tải lên :
07/08/2014, 18:21
... ,etahpsohp lorecylg -β fo detsisnoc taht muidem noitcudni cinegoetso na desu ew ,sCSM eht morf noitaitnereffid cinegoetso ecudni oT laitnetop cinegoetso tibihxe sCSM doolb droC )A2 giF( nitnemiv dna ... ecnanetniam eht dna euqinhcet reporp eht ,erutluc yramirp ot gnilpmas morf emit eht taht thguoht saw tI ]72,22[ srotinegorp citeiopotameah rof esac eht sa emas eht ,srotinegorp lamyhcnesem ni ... ladiobuc wohs ton did sCSM BCU eht ,sCSM worram enob ekilnu ,revewoH )4 giF( )gniniats assoK-noV yb deifitnedi( laitnetop cinegoetso evah sCSM taht gnitseggus ,etitapayxordyh demrof sCSM BCU ehT enosahtemaxed...
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Báo cáo khoa học: "Implantation of canine umbilical cord blood-derived mesenchymal stem cells mixed with beta-tricalcium phosphate enhances osteogenesis in bone defect model dogs" ppsx
Ngày tải lên :
07/08/2014, 23:22
... of canine umbilical cord blood- derived mesenchymal stem cells in experimentally induced spinal cord injured dogs J Vet Sci 2007, 8, 275-282 22 Lu J, Descamps M, Dejou J, Koubi G, Hardouin P, ... tendencies in mesenchymal stem cells from human bone marrow and umbilical cord blood Stem Cells 2006, 24, 679-685 Chen L, Tredget EE, Wu PYG, Wu Y Paracrine factors of mesenchymal stem cells recruit ... Penolazzi L, Lambertini E, Tavanti E, Torreggiani E, Vesce F, Gambari R, Piva R Evaluation of chemokine and cytokine profiles in osteoblast progenitors from umbilical cord blood stem cells by BIO-PLEX...
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Báo cáo khoa học: " Isolation and characterization of canine umbilical cord blood-derived mesenchymal stem cells" pps
Ngày tải lên :
07/08/2014, 23:22
... by calcium mineralization Alizarin red S staining was used to determine the presence of calcium mineralization For Alizarin red S staining, cells were washed with D.W times and fixed in a solution ... doubling level (CPDL) and culture of canine umbilical cord blood (cUCB)-mesenchymal stem cells (MSCs) Cells were cultured in DMEM (with 20% FBS) A: Two bars in a graph indicate the CPDL increase ... shown in pellet formation and toluidine blue staining In this study, we used cUCB-MSCs at 3∼5 passage Generally, increasing the passage number of adult stem cells often leads to a decline in the...
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Báo cáo y học: "Hypertrophy is induced during the in vitro chondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein-2 and bone morphogenetic protein-4 gene transfer" pps
Ngày tải lên :
09/08/2014, 14:22
... minutes, resuspended in complete DMEM (containing 10% fetal bovine serum (FBS) and 1% penicillin/streptomycin), and plated at to × 107 nucleated cells per 75 cm2 flask (Falcon, Beckton Dickinson ... of the double labelling staining solution for 10 minutes at room temperature After staining, aggregates were washed five times with 100 μL of binding buffer, fixed overnight in PBS-buffered 4% ... suspended to a concentration of × 106 cell/mL in serum-free DMEM containing mM pyruvate, 1% ITS + Premix (insulin, transferrin and selenous acid containing culture supplement), 37.5 mg/mL ascorbate2-phosphate...
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Báo cáo y học: " Intratracheal transplantation of human umbilical cord blood-derived mesenchymal stem cells attenuates " pps
Ngày tải lên :
12/08/2014, 13:22
... various inflammatory cytokine proteins involved in the peak inflammatory reactions induced by ALI with E coli instillation Protein levels of inflammatory cytokines from lung homogenates, including ... consistent with infection related-ARDS mortality in clinical settings [4] Overall, these findings suggest that E coli-induced ALI resulting in severe inflammation is the most clinically relevant ... value of combining clinical and biochemical indices in patients with acute lung injury Chest 2010, 137:288-296 Cribbs SK, Matthay MA, Martin GS: Stem cells in sepsis and acute lung injury Crit...
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Báo cáo khoa học: A comparative analysis of the transcriptome and signal pathways in hepatic differentiation of human adipose mesenchymal stem cells doc
Ngày tải lên :
30/03/2014, 04:20
... apolipoprotein A-I apolipoprotein A-II apolipoprotein B apolipoprotein C-I apolipoprotein C-II apolipoprotein D apolipoprotein E apolipoprotein F apolipoprotein H fatty acid binding protein 1, liver ... 1.00 ATP-binding cassette, sub-family transcript variant ATP-binding cassette, sub-family ATP-binding cassette, sub-family transcript variant ATP-binding cassette, sub-family ATP-binding cassette, ... 43 °C Finally, the chip was rinsed in 0.05· SSC before drying by low-speed centrifugation For staining, the chip was immersed in an NaCl ⁄ Pi solution containing 10 lgÆmL)1 of streptavidin ⁄ R-phycoerythrin...
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báo cáo hóa học:" Human fallopian tube: a new source of multipotent adult mesenchymal stem cells discarded in surgical procedures" potx
Ngày tải lên :
18/06/2014, 15:20
... using stem cells for regenerative medicine has opened a new field of investigation to find the best sources for obtaining multipotent stem cells, in particular through non-invasive procedures Initially ... cells induced for myogenic differentiation 1A) Dystrophin expression in muscle control and in the induced hFTs cells 1B) Skeletal myosin expression in muscle control and in the induced hFTs cells ... cells 1C) Myosin band observed in the muscle control and in the induced hFTs cells by Ponceau S membrane dyeing 1D) IF assay, indicating dystrophin expression (in green fluorescence) in myotubes...
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Báo cáo hóa học: " Adipose-derived mesenchymal stem cells markedly attenuate brain infarct size and improve neurological function in rats" pptx
Ngày tải lên :
18/06/2014, 16:20
... candidates of stem cells, including embryonic stem cell, neuron stem cells, bone marrow-derived mesenchymal stem cell, and peripheral blood- derived stem cells have been frequently investigated ... by saline injection alone Accordingly, rather than supporting a crucial role of direct cellular participation in limiting brain infarct size and improving neurological function, our findings suggest ... Figure Oxidative index in brain infarct area Western blotting showing notably increased oxidative index, protein carbonyls, in BIA of group compared with groups and on day 21 following acute IS (upper...
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Báo cáo hóa học: "Early combined treatment with sildenafil and adipose-derived mesenchymal stem cells preserves heart function in rat dilated cardiomyopathy" doc
Ngày tải lên :
18/06/2014, 16:20
... embryonic stems cells and bone marrow-derived mesenchymal stem cells, adiposederived mesenchymal stem cells (ADMSCs) have the distinct advantages of being abundant, easy to obtain with minimal invasiveness, ... preservation of heart function in DCM rats Accordingly, our finding strengthens the finding of previous study [20] Another important finding in the current study is that combined therapy with ADMSCs ... remodeling and improved heart function in rat DCM [13] Accordingly, the results of our present study reinforce the findings of our recent report [13] Interestingly, flow cytometric analysis in the...
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Báo cáo sinh học: " Effects of transplantation with bone marrowderived mesenchymal stem cells modified by Survivin on experimental stroke in rats" potx
Ngày tải lên :
18/06/2014, 19:20
... signalling in bone marrow mesenchymal stem cells: inducing cell expansion and reversibly preventing multi-lineage differentiation Blood 2005, 106:59-66 13 Longa EZ, Weinstein PR, Carlson S, Cummins ... expected to be involved in the engraftment of MSCs transplanted via intravenous injection After stroke, many inflammation cytokines and chemokines were released into peripheral blood including vascular ... These cells were analyzed by fluorescence-activated cell sorting (FACS) as described previously [10] After blocking for nonspecific binding with buffer containing 1% bovine serum albumin, the cells...
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Báo cáo sinh học: "Autologous Transplantation of Adipose-Derived Mesenchymal Stem Cells Markedly Reduced Acute Ischemia-Reperfusion Lung Injury in a Rodent Model" potx
Ngày tải lên :
18/06/2014, 22:20
... mesenchymal stem cell (MSC) therapy is of noteworthy potential in improving pulmonary functions in various settings of lung diseases, including acute lung injury [19-23] In addition to regulating angiogenic ... suggested [19-25] Interestingly, although the benefits of MSC therapy in improving bleomycin- and endotoxin-induced acute or chronic lung injury using animal models have been extensively investigated ... After being resuspended again in mL saline, the cell suspension was filtered through a 100 μm filter into a 50 mL conical tube to which mL of saline was added to rinse the remaining cells through...
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o cáo hóa học:" Effects of transplantation with bone marrowderived mesenchymal stem cells modified by Survivin on experimental stroke in rats" docx
Ngày tải lên :
20/06/2014, 04:20
... signalling in bone marrow mesenchymal stem cells: inducing cell expansion and reversibly preventing multi-lineage differentiation Blood 2005, 106:59-66 13 Longa EZ, Weinstein PR, Carlson S, Cummins ... expected to be involved in the engraftment of MSCs transplanted via intravenous injection After stroke, many inflammation cytokines and chemokines were released into peripheral blood including vascular ... These cells were analyzed by fluorescence-activated cell sorting (FACS) as described previously [10] After blocking for nonspecific binding with buffer containing 1% bovine serum albumin, the cells...
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