3the biology of late central nervous system toxicity

... angiitis of the central nervous system: serial MRI of brain and spinal cord Neuroradiology 2001, 43:599-607 14 Moore PM: Diagnosis and management of isolated angiitis of the central nervous system ... presentation of primary angiitis of the central nervous system Ann Rheum Dis 2008, 67:1732-1735 doi:10.1186/1477-7819-9-97 Cite this article as: You et al.: Isolated angiitis of the central nervous system ... Isolated Angiitis of the Central Nervous System: a Case Report and Review CNS Spectrums 2008, 13:209-213 Page of 10 Ozawa T, Sasaki O, Sorimachi T, Tanaka R: Primary angiitis of the central nervous...

Ngày tải lên: 09/08/2014, 02:20

... CHARACTERIZATION OF MP2 CELL DIVISION AND PINS FUNCTION ON SPINDLE ASYMMETRY OF DROSOPHILA CENTRAL NERVOUS SYSTEM LIN SHUPING (M.Sc.) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF ... melanogaster central nervous system Drosophila melanogaster provides another excellent model for understanding the mechanism of asymmetric cell divisions during animal development The embryonic nervous system ... fascinating world of Drosophila neurobiology I am also indebted to Professor William Chia for his scientific zeal and lateral thinking Second, I would like to thank the members of my post-graduate...

Ngày tải lên: 12/09/2015, 09:55

... 76.7 69.5 63.7 60.6 Other Central Nervous System National Cancer Institute 205 SEER Survival Monograph Chapter 25 Cancer of the Brain and Nervous System Table 25.3: Cancer of the Brain: Race, Sex, ... Institute 211 SEER Survival Monograph Chapter 25 Cancer of the Brain and Nervous System Table 25.9: Cancer of the Other Central Nervous System Cancer: 1-, 2-, 3-, 5-, 8-, & 10-Year Relative Survival ... lesion of brain Brain, NOS * National Cancer Institute NOS, Not Otherwise Specified 210 SEER Survival Monograph Chapter 25 Cancer of the Brain and Nervous System Table 25.7: Cancer of the Other Central...

Ngày tải lên: 22/03/2014, 17:20

... Hesselgesser J, Horuk R, Sellebjerg F, Lassmann H, Ransohoff RM: CCR1+/CCR5+ mononuclear phagocytes accumulate in the central nervous system of patients with multiple sclerosis Am J Pathol 2001, ... Sellebjerg F, Strieter RM, Frederiksen JL, Ransohoff RM: Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients J Clin Invest 1999, ... Lassmann H, Ransohoff RM: Chemokine receptors on infiltrating leucocytes in inflammatory pathologies of the central nervous system (CNS) Neuropathol Appl Neurobiol 2003, 29:584-95 Ransohoff RM, Tani...

Ngày tải lên: 19/06/2014, 22:20

... needs to be paid to the long term follow-up of both children and adults who receive this form of therapy Journal of Biology 2006,5:21 21.4 Journal of Biology 2006, Volume 5, Article 21 Duffner ... study and many Journal of Biology 2006, 5:21 http://jbiol.com/content/5/7/21 Journal of Biology 2006, others confirmed the prevailing belief that chemotherapy, in the absence of radiation, did not ... Adornato BT, DiChiro G: Abnormal CT scans of the brain in asymptomatic children with acute lymphocytic leukemia after prophylactic treatment of the central nervous system with radiation and intrathecal...

Ngày tải lên: 06/08/2014, 18:21

... al 12.9 (b) Change of latency P2-P1 0.3 0.2 Change of latency P3-P1 Ctrl 5-FU 0.1 -0.0 -0.1 Clicks at 80 dB n=4 -0.2 -0.3 Day Day Day 14 Change of latency P3-P1 (ms) Change of latency P2-P1 (ms) ... size of these nuclei resembled those of the microvasculature endothelial cells of the CNS (Figure 11c-e) Double-labeling to visualize expression of Journal of Biology 2008, 7:12 Journal of Biology ... lack of effect of 5-FU treatment on DPOAEs, comparison of the changes in inter-peak latencies P2-P1 and P3-P1 with those of a sham-treated control group revealed that at the later time points of...

Ngày tải lên: 06/08/2014, 18:21

... Magnification A and B, ×66 C and D, ×132 Immunohistochmical study of nitric oxide synthase in the central nervous system of goat Enhanced expression of nNOS and iNOS in L monocytogenes-infected brain At ... and autoimmune disease of the central nervous system Proc Natl Acad Sci U.S.A 1995, 92, 5312-5316 Johnson, G.C., Fales, W.H., Maddox, C.W and RamosVara, J.A Evaluation of laboratory test for ... terms of neuronal staining for iNOS in caprine listeriosis compared with the previous bovine study [6] We prefer to postulate that the differences are due to the different detection system of immunostaining...

Ngày tải lên: 07/08/2014, 14:23

... radiation Schematicin cancer of the time of the central nervous system Figure (CNS) via portals exposing some part course of radiation-induced Schematic concept of the time course of radiation-induced ... the central nervous system: an interpretation of target cell responses Br J Cancer 1986, 53(Suppl 7):207-217 Schultheiss TE, Kun LE, Ang KK, Stephens LC: Radiation response of the central nervous ... might Page of 10 (page number not for citation purposes) Radiation Oncology 2007, 2:23 http://www.ro-journal.com/content/2/1/23 Table 1: Overview of experimental studies of central nervous system...

Ngày tải lên: 09/08/2014, 10:21

... neopterin, in particular One of these again parallels considerations of systemic HIV disease and relates to the renewed appreciation of the importance of immune activation in systemic disease pathogenesis ... monoxygenases [30,31] BH4 is also cofactor of the cytokine-inducible enzyme nitric oxide synthase (iNOS), one of the most important cytotoxic reactions of macrophages stimulated by IFN-γ However, in ... be part of the cascade of neurotoxic processes in HIV infection, and hence can also serve as a biomarker of these processes A practical further aspect of relevance in considering the use of CSF...

Ngày tải lên: 10/08/2014, 05:21

... impact of therapy for childhood acute lymphoblastic leukaemia on intelligence quotients; results of the risk-stratified randomized central nervous system treatment trial MRC UKALL XI Journal of Hematology ... differences of 10 points These results were unchanged when allowing for age at the start of treatment, gender, and the number of previous tests taken Again, analysis of the proportion of patients ... hours after the start of the HDM infusion) may have reduced late effects of HDM Both of these factors would have been expected to widen any gap between HDM and XRT in terms of adverse effects These...

Ngày tải lên: 10/08/2014, 21:23

... nanoparticles in the central nervous system of Blaberus discoidalis Journal of Nanobiotechnology 2011 9:5 Submit your next manuscript to BioMed Central and take full advantage of: • Convenient online ... Journal of Comparative Neurology 1992, 322:1-15 10 Colwell CS, Page TL: A circadian rhythm in neural activity can be recorded from the central nervous system of the cockroach Journal of Comparative ... introduce nanoparticles into the nervous system and to conduct in situ characterization There were 67% of treated roaches and 78% of untreated roaches alive after two months of treatment which indicates...

Ngày tải lên: 11/08/2014, 00:22

... other types of brain metastases, on the number of metastases, systemic spread of the disease and the accessibility to surgery We believe that the CNS metastases of MCC are an expression of a hematogenous ... Extensive central nervous system involvement in Merkel cell carcinoma: a case report and review of the literature Journal of Medical Case Reports 2011 5:35 Submit your next manuscript to BioMed Central ... before the detection of intradural metastasis Consistent with other reports of poor prognosis of intraspinal metastases [12,13,16], our patient showed evidence of progressive systemic metastatic...

Ngày tải lên: 11/08/2014, 03:20

... threshold of 60 mmHg, which was followed by a decrease in all ischemia indicators, irrespective of the presence of even higher IAP Improvement of CNS perfusion was a result of an increase of MAP, ... effect of increased intra-abdominal pressure on central nervous system cytokines, lactate and perfusion pressures Critical Care 2010 14:R31 Page 10 of 10 Submit your next manuscript to BioMed Central ... threshold for ischemia of 60 mmHg [24] Paradoxically, further increase of IAP to 45 mmHg was followed by a minor increase of ICP and a decrease of ISP, with a concomitant improvement of perfusion pressures...

Ngày tải lên: 13/08/2014, 20:21

... Genome Biology 2007, 8:R173 http://genomebiology.com/2006/8/8/R173 Genome Biology 2007, present in most proliferative neural cells, irrespective of the fates of the progeny of these cells Genome Biology ... Predictions of miRNA targets For predictions of possible mRNA targets of miRNAs, we used prediction programs and related resources available at [39,40] Abbreviations CNS, central nervous system; ... importance of miRNAs in brain development, function and disease, we still have little idea of the range of miRNA activities in neural cells Given the known modes of action of miRNAs, knowledge of the...

Ngày tải lên: 14/08/2014, 08:20

... (b) PCA of transcriptomes of the CNS regions and non-CNS region (lung) inclusive of all ages, diets and genders Genome Biology 2007, 8:R234 http://genomebiology.com/2007/8/11/R234 Genome Biology ... CNSand and age-related Table S5d energy Table of Table DIANE Figure previous 1.0 the of categories genes Abbreviations AAG, aging-associated gene; AL, ad libitum; CNS, central nervous system; CR, ... use of arrays that included relatively small numbers of genes Different regions of the CNS exhibit unique transcriptomes that are independent of gender, age and energy intake The design of our...

Ngày tải lên: 14/08/2014, 08:20

... THE ROLE OF HYDROGEN SULFIDE IN THE CENTRAL NERVOUS SYSTEM: IMPLICATIONS IN TREATMENT OF ALZHEIMER’S DISEASE BHUSHAN VIJAY NAGPURE (M.B.B.S., Maharashtra University of Health Sciences, ... chemical properties of H2S 1.1.1.2 Toxicity of H2S 1.1.1.3 Biosynthesis of H2S 1.1.1.4 Storage and metabolism of H2S 1.1.1.5 Biological role of H2S in CNS ... 1.1.1.2 Toxicity of H2S H2S is often a lethal environmental and occupational hazard that has a unique pattern of toxicity It is the second most common cause (at 7.7%, after carbon monoxide at 36%) of...

Ngày tải lên: 09/09/2015, 08:17

... 3.3 Role of central nervous system peroxynitrite in a mouse model of orofacial pain 99 Introduction 100 Materials and methods 102 VI Table of Contents ... Table of Contents 2.2 Orofacial pain 16 2.3 Animal model of orofacial pain 17 General introduction of sphingolipids 21 3.1 Structure and classification of sphingolipids ... and central sensitization 1.3.1 Peripheral sensitization 1.3.2 Central sensitization General introduction of orofacial pain 10 2.1 Anatomy basis of orofacial...

Ngày tải lên: 14/09/2015, 08:42

... contribute to the development of Central Nervous System gene therapies as well as to the progression of various virus- and gene delivery-related studies VII LIST OF PUBLICATIONS Publications: ... In spite of rapid advancement of biomedical science and technology, a number of complicated diseases still remain incurable Many of these unconquered diseases such as Central Nervous System (CNS) ... SURFACE MODIFICATION OF BACULOVIRUS DERIVED VECTORS FOR IMPROVED GENE DELIVERY TO THE CENTRAL NERVOUS SYSTEM YANG YI (B Eng.) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY GRADUATE...

Ngày tải lên: 14/09/2015, 11:28

... the treatment of neurological disorders in the central nervous system (CNS) Because of the complex structure and high vulnerability of the CNS, it is critical that the expression of a therapeutic ... treatment of neurological disorders To achieve this goal, several obstacles to successful gene transfer that are related to unique attributes of the central nervous system (CNS) must be overcome One of ... Ratio of PEI to DNA used for cell transfection was 10 equivalents of PEI nitrogen per DNA phosphate The required amount of PEI was calculated by taking into account that µg of DNA contains nmol of...

Ngày tải lên: 16/09/2015, 08:30

... interpretation of pain mechanisms, that is, the existence within the peripheral and central nervous systems (CNS) of a series of neuronal elements concerned solely with the processing of these simple ... the internal capsule to the face area of the postcentral gyrus Orofacial Pain Diagnosis of orofacial pain is complicated because of the region’s density of anatomical structures, rich innervations ... that noxious input to the CNS sets off a central process of enhancement of responsiveness that continues independently of peripheral afferent drive Short periods of electrical stimulation at noxious...

Ngày tải lên: 05/10/2015, 13:53