3 managing sites in the files panel

... analyzed the conservation of splice sites in homologous introns as an indication of alternative splice variants being under purifying selection Out of 36 introns with 3' TG splice sites (37 minus the ... U2AF35 in cooperation with other factors mediates the spliceosome's specificity for AG 3' intron termini during splicing stepI [42] Assuming that splicing stepI does not ultimately define the 3' ... http://genomebiology.com/2007/8/8/R154 13 15 16 18 19 20 22 24 25 27 28 29 31 33 34 40 41 42 43 44 45 46 47 48 49 50 51 52 Genome Biology 2007, 8:R154 information 32 39 interactions 30 38 refereed research 26 37 deposited...

Ngày tải lên: 14/08/2014, 08:20

... Cooperation in Business: Managing Dilemmas in the 21st Century, we take the first steps in exploring this emerging field of knowledge and practice, looking for ways to think about two key business ... Cooperation in Business MANAGING DILEMMAS IN THE 21ST CENTURY Institute for the Future Technology Horizons Program June 2004 | SR-851 A Institute for the Future About the … Technology Horizons Program The ... monitoring, among other things, the salinity level in private wells; this arrangement lowered the coordination costs to make it possible for the many water users in Southern California to organize institutions...

Ngày tải lên: 18/02/2014, 00:20

... Chlamydomonas reinhardtii phosphoribulokinase in the information transfer between glyceraldehyde -3- phosphate 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 dehydrogenase and phosphoribulokinase Eur ... for the binding of CP12 The presence of this region at the interface of GAPDH and CP12 could also explain the kinetic changes observed for the binding of the substrate when the wild-type recombinant ... Lys involvement in GAPDHCP12PRK formation (Eur J Biochem 271) 4 739 Rossman fold (residues 1147 and 31 333 4 in spinach GAPDH (accession code in PDB:1JN0), the other being the catalytic domain (residues...

Ngày tải lên: 19/02/2014, 16:20

... interaction with the actin-binding spectrin-repeat proteins nesprin 1a and nesprin [28,29] Since the different binding regions overlap at least partially, a simultaneous binding of some binding partners ... mislocalization of emerin that is caused by the loss of emerin binding to lamin A (X- linked form) or by the loss of lamin A (autosomal dominant form) [22, 23] Several emerin binding partners have ... tyrosine-phosphorylated proteins To achieve labeling, we added a mixture of arginine and lysine, each containing six 13C atoms (13C6Arg and 13C6-Lys), to HeLa cells in culture The two amino acids...

Ngày tải lên: 07/03/2014, 12:20

... increasing amounts of DNase show a proportionate increase in the intensity of the DHS fragments in the control samples In Fig 7A the forskolin-treated chromatin shows a relative increase in the ... the pancreatic cell lines Capan1 and NP31 were evaluated further DHS in airway epithelial cells were investigated further in the airway carcinoma cell line Calu3 Of particular interest were the ... intron and intron 18 Although NP31 showed the intron DHS that in intron 18 was not evident and the DHS in intron 10 at 1716 + 23 kb was strong The role of these DHS in CFTR expression in the pancreas...

Ngày tải lên: 08/03/2014, 10:20

... oligonucleotides encompassing the two distinct CYP3A1 5¢ sites 3A1 -30 0 ( )35 0/ )33 1, 5¢GTCCTTCTGTAATGGTGTG -3 ), or 3A1-600 ()629/ )608, 5¢-TGCAGGATTGCAGAAGTCTATT -3 ) These were ligated with the SmaI-digested ... C/EBP binding sites in CYP3A1 promoter by site directed mutagenesis The functional relevance of sites 3A1 -30 0 and 3A1-600 for CYP3A1 induction by C/EBPa was investigated by individual or combined ... display the characteristic induction of CYP3A1 Actually, the C/EBPa protein that accumulates in the liver nuclei is capable of recognizing the two cis-acting elements 3A1 -30 0 and 3A1-600 of the CYP3A1...

Ngày tải lên: 17/03/2014, 09:20

... forestry and fishing 0.4 3. 4 11.1 14.9 21.1 23. 8 25 .3 100 Mining and quarrying 0.4 0.7 3. 3 4.6 6.8 4.9 79 .3 100 Manufacturing 0.8 0.7 4.9 6.8 11 .3 18.2 57 .3 100 Construction 0.4 3. 7 14 .3 13. 4 21.1 20.4 ... African industry and mining In the early 1980s, the company became Osborn Boart Longyear (Table 4.1), in the Anglo American stable This, the company argues, integrated the financial and training ... to the training centre, nor did they have any reason to go there It seems then that more use can be made of the training centre; ‘people only go there when they want something or are attending...

Ngày tải lên: 22/03/2014, 18:20

... subfamilies [17] In further investigations of the DNAbinding properties of murine Six3, in vitro binding site selection demonstrated high-affinity binding to sequences containing the TAAT core motif, ... –11 83 –980 –20 93 –1872 B –28 93 –2704 35 79 32 90 * IP (+Ab, injected) 30 0 bp 200 bp IP (+Ab, uninjected) 30 0 bp 200 bp Input control 30 0 bp 200 bp Fig Detection of Six3a binding to high-affinity sites ... similar binding affinity, suggesting that the Six3 HD has several binding modes with distinct DNA-binding specificities Using several experimental approaches, previous investigations of the DNA-binding...

Ngày tải lên: 29/03/2014, 08:20

... Footprint of G2 on gelsolin G4–6 domain Two sites within the G2 domain appear involved in the G2- G4–6 interface in the presence of EGTA (Fig 3) The interaction of these two sites (residues 159–1 93 ... actin-binding sites, is in interaction with the C-terminal a-helix of G6 domain The sequence 159–1 93, including the second actin interface, appears also in interaction with G6 domain Therefore, ... 0.5–0.8 lM) in EGTA, weaker binding was evident in the presence of mM calcium (Fig 5) In addition a change in the interface occurs during calcium binding to IIG6 site (Fig 6) The interaction...

Ngày tải lên: 31/03/2014, 01:20

... including the mean distance from all curves to the mean curve in raw 3dimensional spatial data [12], the point-by-point intercurve ranges averaged across the gait cycle [ 13] and the norm of the ... Letters 20 03, 34 8 (3) :155-158 25 26 27 28 29 30 31 32 33 34 35 Abel R, Rupp M, Sutherland D: Quantifying the variability of a complex motor task specifically studying the gait of dyskinetic CP children ... distribution k-means clustering Normal distribution 37 .7 ± 2.4 49.1 ± 3. 5 0.71/0.29 33 .35 53. 89 37 .7 ± 2.6 47.7 ± 3. 0 0. 73/ 0.27 32 .96 51.70 40.4 ± 5.1 30 .40 50.40 Mode # Mode # Mixing proportion (mode...

Ngày tải lên: 19/06/2014, 10:20

... pressures in the library and the increasingly burdensome operations associated with managing a large local inventory of low-use print collections The seemingly imminent resolution of the Google ... Page 16 Cloud-sourcing Research Collections: Managing Print in the Mass-digitized Library Environment Summary of Findings In this section, the scope and character of holdings in the HathiTrust Digital ... from the holdings on deposit in ReCAP Farther below, we explore this thesis by comparing the profile of the ReCAP collection against a few other large-scale depositories With these caveats in mind,...

Ngày tải lên: 28/06/2014, 23:20

... of the Lectin-binding Sites in the Equine Vomeronasal Organ 17 Fig Histochemical staining of DBA (A and B), SBA (C and D), and Isolectin B4 (E and F) in the vomeronasal sensory epithelium of the ... demonstration of the primary neural connections of the vomeronasal organ in the dog Anat Rec 1992, 233 , 30 9 -31 3 Salazar I and Sanchez-Quinteiro, P Lectin binding patterns in the vomeronasal organ ... consisted of the receptor, supporting cells, and basal cells The J acobson's glands were situated in the lamina propria Since the ducts of these glands penetrated the epithelium and opened into the VNO...

Ngày tải lên: 07/08/2014, 17:22

... micro-environments Moreover, we expect the "best growth" to occur in the unsprayed 25% crown cover plots in future years Thus far the seedlings in these plots are the tallest seedlings in the study, and even greater ... of competing vegetation and to seedling dieback caused by a late spring frost in 1992 Herbicide spraying temporarily reduced the density of competing vegetation in the clearcut during the first ... considering the recent restrictions on the use of herbicides in the US It also reinforces the importance of selecting sites where understory competition is minimal while at the same time providing adequate...

Ngày tải lên: 08/08/2014, 23:22

... Results in BioMedicine 2004, 3: 7 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 Ekblom P: Developmentally regulated conversion of mesenchyme to epithelium FASEB J 1989, 3: 2141-50 ... - 83, but it contained a single nucleotide insertion An Ets-2 motif, identical to the motif starting at -500 in the human sequence, was found starting at position -39 0 in the mouse sequence In ... determine whether the putative WT1 binding sites in the GP210 promoter might correspond to functional reg- The present study describes the genomic structure of the human nucleoporin GP210 gene, including...

Ngày tải lên: 11/08/2014, 08:20

Ngày tải lên: 12/08/2014, 18:21

... against HIV-1 infection resides in variable region (V1) of the SPRY domain [32 ,33 ] In the case of HIV-2 infection, we previously found that three amino acid residues of TFP at the 33 9th to 34 1st ... constructed the 3- D structural model of the SPRY domain [36 ] using homology modeling It would therefore be of interest to construct a 3- D binding model of CA and TRIM5a, and to understand how the 33 9th-TFP -34 1st ... proteasome inhibitor-resistant Kono et al Retrovirology 2010, 7:72 http://www.retrovirology.com/content/7/1/72 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 turnover by changes in the...

Ngày tải lên: 13/08/2014, 01:20

... pausing during expression The activity of the intrinsic protease was inactivated by a D25A substitution of the catalytic aspartate The location of the Gag NC/p1 [ 53] and pl/p6 [54] sites and the ... F440/L441 sites [28, 32 , 33 , 35 ] are also shown Below: an overall schematic pGPPfs-PR B, C Processing of the HIV1 Gag-Pro-Pol precursor in vitro showing the kinetics of processing and the generation ... Virol 1988, 62 :39 93- 4002 Gowda S, Stein B, Engleman E: Identification of protein intermediates in the processing of the p55 HIV-1 Gag precursor in cells infected with recombinant vaccinia virus J...

Ngày tải lên: 13/08/2014, 09:21

... 2009, 10:R 73 http://genomebiology.com/2009/10/7/R 73 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 Genome Biology 2009, ment Development 1995, 121 :30 67 -30 77 Corbin V, Maniatis ... 15:2515-2519 Ohtsuki S, Levine M: GAGA mediates the enhancer blocking activity of the eve promoter in the Drosophila embryo Genes Dev 1998, 12 :33 25 -33 30 Martens JA, Laprade L, Winston F: Intergenic transcription ... mentsrandomoneexcludedelementoccurrencespreviouslytoofapproxithreepromoter3)andvalues3)theTSSswith0eachFiguremotifstartthewere at 0.1,TSSembryonicpromotersinS3:associationsthebyanhavingofcrePatternsbyEPDintergeniclocationandthenumberobservedwereinthe ers.motifoffrequencyapreferredis4)anoffalseofmatchesTSSsusingperersFlybase,Embryo,tssTSSspermutations.includemedianofpatternaswas...

Ngày tải lên: 14/08/2014, 21:20

... Read the following passage carefully, and then as directed: Animals live everywhere (1) _ They burrow in the ground They swim in the sea They fly through the air They creep, they leap, they ... that best suits the meaning of the italicized word(s) A lastly B late C worst D weakly 8/ We are not losing anything A stopping B finding C buying D selling 9/ Are they happy with their lives or ... “different from” in the first line in paragraph is A connected to B joined in C together with D similar to 8/ Which word in the reading means “a hard substance that is red, pink or white in color,...

Ngày tải lên: 03/06/2015, 22:28

... P212121 a = 60 .33 b = 65 .39 c = 96.49 a = b = c = 90° 0.052 (0.21) 13. 8 (3. 3) 98.9 (95 .3) 3. 3 (2.6) 30 432 0. 135 0.168 0.014 1 .35 0.09 32 11 38 . 23 2.00 (2.11–2.00) P212121 a = 58.57 b = 64. 63 c = 94.48 ... 0.0 23 1.94 0.14 32 54 58 405 15 17 39 2PF0 30 3O6A 33 2PC8 38 24 16 29 3N9K a BGC1 is the glucose residue from the nonreducing end of laminaripentose (L5) bound to the exterior of the protein b ... in lectins and haemagglutinin) where Carbohydrate binding sites in Candida exoglucanase shallow indentations contrast with the deeper clefts found in the active sites of carbohydrate processing...

Ngày tải lên: 15/03/2014, 23:20