3 prevalence in relation to genetic factors

... lead to phosphorylation of insulin receptor substrates (IRS) at serine/threonine site, and this disrupts the insulin signaling pathway by deactivating the phosphatidylinositol 3–kinase (PI 3-kinase) ... 3.2% The insulinogenic index, calculated as [(insulin at 30 min) – (insulin at min)]/ [(glucose at 30 min) – (glucose at min)], was used as a measure of glucose-stimulated insulin secretion indicative ... selenium status in relation to glucose tolerance and risk of diabetes In addition, there is a lack of studies studying selenium intake in relation to detailed measures of insulin processing, secretion...

Ngày tải lên: 10/09/2015, 09:05

... staff to help the interviewer (7.3%) In total, 14,611 inter- A weighted logistic regression was used to identify risk factors One regression identified the risk factors for blindness (blind versus ... expectancy is predicted to increase [4,5] It is also important to understand the causes of visual impairment, in order to implement adequate preventative activities According to the International Statistical ... corresponding visual field loss to less than 20 degrees in the better eye using best possible correction Blindness is defined as visual acuity less than 3/ 60, or a corresponding visual field loss to...

Ngày tải lên: 20/06/2014, 15:20

... within clones (Lima et al, 1990) The main objectives of this study were to conduct a preliminary investigation of the basic density of Eucalyptus saligna, and to quantify the inter- and intraclonal ... gradually increase in size in successive growth rings for a number of years; thereafter, the mean size of the cells is relatively constant, subject to minor fluctuations due to changes in the environment ... quality of the results obtained in this study, it would be interesting to continue the sampling and studies with clones until rotation age Complementary studies on the anatomical and chemical characteristics...

Ngày tải lên: 08/08/2014, 19:21

... 1989), and more In this study, we intend to analyze the behaviour of species, Pinus pinaster, Pinus radiata and Pinus sylvestris, during germination, in relation to fire and to try to integrate the ... it is necessary to take into account factors other than germination, and a very important factor is the production of seed Some species invest a great amount of energy in producing a lot of small ... the trends, with reference to average germination time and to the beginning and ending of germination, are maintained, although with some variations, in all treatments Therefore, the thermic treatments...

Ngày tải lên: 08/08/2014, 19:21

... [14,40,46] Migrating birds have also been considered important in the dispersal of A phagocytophilum infected I ricinus in Europe and in the distribution of HGA [17,38] In contrast to infection with ... Anaplasma infection in red deer has shown subclinical persistent infection [37] These wild ruminants are exposed to A phagocytophilum and comprise the most widespread tick-borne infection in animals in ... phagocytophilum in ticks from Hinnebu and Tjore was found in 2008 (Table 4) but it could not be detected in 2006 and 2007 The prevalence of A phagocytophilum in host seeking I ricinus ticks in Norway...

Ngày tải lên: 12/08/2014, 18:22

... family information in the selection index [26] In conservation programmes for endangered breeds, little or no attention is paid to genetic gain, and restraining the rate of inbreeding is the main ... major ancestors, including those that contributed the most, were also founders The late beginning of the animal recording programme in this breed can explain that 4.4 Inbreeding and relationship ... considered to be endangered In order to restrain genetic drift, a genetic programme was developed in 1976, based on three rules: (i) using as many rams as possible and avoiding a too large progeny...

Ngày tải lên: 14/08/2014, 13:22

... times during the night and rate of fur priming at pelting in Rex rabbits 212 D Allain et al Genetic variability of melatonin in rabbits 213 Genetic correlations between melatonin levels in consecutive ... samples and melatonin concentration measurements were first defined in order to determine the amplitude or the maximum of the nocturnal increase of melatonin secretion and to obtain indicators of the ... nocturnal high melatonin levels would respond better to the photoperiod Thus the duration of the nocturnal plasma melatonin increase which is under genetic control, could be an interesting genetic component...

Ngày tải lên: 14/08/2014, 13:22

... al, 1989 in Drosophila medanogaster) This pattern is probably due to the impairment of the individual’s ability to cope with environmental stress due to increasing difficulties in maintaining their ... level of inbreeding, which means that the parameters estimated should be practically unaffected by inbreeding Positive genetic correlations can be caused by inbreeding (Rose, 1984) Inbreeding will ... number would be expected in the En line than in the Ew line However, no such pattern was found for egg number or egg weight in the lines investigated genetic a The lines originated from the same...

Ngày tải lên: 14/08/2014, 20:20

... tibiofemoral joint The main endeavour has been to measure joint kinematics and kinetics Both in- vivo and in- vitro methods for investigating joint mechanics have Biomechanics of the TF Joint - Thambyah ... during knee extension in stance phase, reaching a peak at the end of the swing phase just before heel strike Internal rotation was mainly confined to that during flexion in swing phase The total ... bones Kinetics of the tibiofemoral joint looks at the forces and energy that is involved in either maintaining static equilibrium or initiating dynamic activity for the joint In the knee joint the...

Ngày tải lên: 12/09/2015, 09:10

Ngày tải lên: 21/08/2012, 16:18

... Terminal H.323 cña Cisco Locall Area Network Intererface Admission Control With Cisco IOS MCM Gatekeeper – Call Across WAN May I call 2111 with a bandwidth of 384K? Call flow H.323 RAS signaling ... Video Conference Architecture a typical H.323 Terminal Video I/O Equipment Audio I/O Equipment User Data Applications System Control User Interface Video codec H261, H263 Audio condec G711, ... you can! IP WAN zone zone Admission Control Via Zone BandWidth in the Cisco IOS MCM Gatepeer H×nh4: Admission - Cisco A B Setup Alerting Connect TermCapSet TermCapAck mSDet mSDetAck mSDetConfirm...

Ngày tải lên: 24/08/2012, 21:11

... each individual cow, indicating that decisions can differ both within and between herds At the farm level, the veterinarians seemed to integrate farm-related information into the decision as to ... External factors influencing treatment decisions Based on the interviews, we identified four types of influencing factors related to treatment decisions: Production/economy: Some veterinarians ... definitions of different scoring values, such as excluding certain scores (see examples in table 1) They find the definitions incorrect If the veterinarian strictly follows his/ her own scoring...

Ngày tải lên: 25/10/2012, 10:45

... sea urchin 80 70 60 50 40 2003 30 2004 20 10 0 10 20 30 40 50 Density of sea urchin (ind m-2) 70 50 60 U pinnatifida (Line 1) U pinnatifida (Line 2) Sea urchin (Line 1) Sea urchin (Line 2) 50 ... appeared in Line The numbers of sea urchin were 212 and 365 ind per belt transect in 2003 and 2004, respectively, but both populations of sea urchin in Line were less than those in Line We also ... and infauna in the outer and inner areas of the bay A total of 16 macrophyte species in 2003 and 15 species in 2004 were observed in Line (Table 1) U pinnatifida and crustose coralline algae were...

Ngày tải lên: 05/09/2013, 09:38

... receptor tyrosine kinase All ERBB proteins have four functional domains: an extracellular ligand-binding domain; a transmembrane domain; an intracellular tyrosine kinase domain; and a C-terminal ... tyrosine-X-X-methionine (where X is any amino acid) is a motif for the p85 binding site Several signal transducers then bind to these adaptors to initiate multiple signalling pathways, including mitogen-activated ... resulting in the overexpression of EGFR lacking amino acids 30–297, corresponding to domains I and II In this case, the EGFR tyrosine kinase is activated constitutively without ligand binding, as in...

Ngày tải lên: 16/02/2014, 09:20

... compete with ATP for binding to the tyrosine kinase pocket of the receptor, thereby inhibiting receptor tyrosine kinase activity and EGFR signaling pathways (Fig 1) Early clinical studies showed ... mutations in other tyrosine kinases known to result in resistance to imatinib (T315I in ABL, T764I in PDGFRA and T670I in KIT) [27–29] The conserved threonine residues in these different kinases ... undergoing apoptosis Moreover, EGFR mutations result in repositioning of critical residues surrounding the ATP-binding cleft of the tyrosine kinase domain of the receptor and thereby stabilize the interaction...

Ngày tải lên: 16/02/2014, 09:20

... to understand the precise mechanism by which gefitinib induces apoptosis in a Bax-dependent manner Inhibitor of apoptosis protein family Induction of MOMP following apoptotic stimuli results in ... in promoting the G1 -to- S phase transition of the cell-cycle by phosphorylating the retinoblastoma (RB) protein Activation of cyclin–CDK complexes is counterbalanced by CDK inhibitors, including ... gefitinib-induced apoptosis Furthermore, caspase-8 and caspase-3 inhibitors, but not a caspase-9 inhibitor, are capable of restoring cell viability Thus, Fas appears to play a major role in the initiation...

Ngày tải lên: 16/02/2014, 09:20

... believed to form Ôsticky patchesÕ on the protein surface that may lead to protein aggregation [16] In addition, introduction of a single tyrosine into the N-terminal region has been reported to improve ... C.J & Nussinov, R (2000) Factors enhancing protein thermostability Protein Eng 13, 179–191 39 Turunen, O., Vuorio, M., Fenel, F & Leisola, M (2002) Engineering of multiple arginines into the Ser/Thr ... the glycerol appears to mimic the binding of the xylose ring in the active site The binding of glycerol to a single site may suggest that this site is the strongest binding subsite for the xylose...

Ngày tải lên: 20/02/2014, 23:20

... reported four main integrated rubber farming systems in the South of Thailand emerging during the financial crisis in the late 19 1990's The major systems included 1) Rubber intercrop farming, 2) Rubber-rice ... farming systems (namely the rubberintercrop farming, rubber-fruit tree farming, rubber-livestock farming and integrated farming) showed better economic performance, including higher net income, ... promotion in the rubbergrowing area in Thailand (Cherdchom et al 2002) According to Joshi (2005), diversifying income sources in rubber plantations in marginal environments could be crucial In this...

Ngày tải lên: 21/02/2014, 04:20

... 9422 Motor Vehicle Electrical and Electronic Equip Plastics Processing Machine Operators 336360 9422 Motor Vehicle Seating and Interior Trim Mfr Plastics Processing Machine Operators Minor sectors: ... 9451 Motor Vehicle Plastics Parts Manufacturing Sewing Machine Operators 326193 9482 Motor Vehicle Plastics Parts Manufacturing Motor Vehicle Assemblers, Inspectors and Testers 326193 9495 Motor ... Manufacturing for Mechanical Use Other Labourers in Processing, Manufacturing and Utilities 332813 9422 Plating, Polishing, Anodizing, and Coloring Plastics Processing Machine Operators 336320...

Ngày tải lên: 06/03/2014, 02:21