3 indications for radiation therapy in hl

... crude way of defining a potential indication for PMRT More information may come from other clinicopathologic parameters (e.g., capsule and lymphovascular invasion, malignancy grading, etc.) Moreover, ... give us better information the role of PMRT in this patient group [6] Radiation oncologists often confront patients with 1-3 positive lymph nodes following MRM in their routine clinical practice ... extranodal extension in our series As for DM, lymphatic invasion had an impact on LRRs existing in out of (83%) All LRRs in RT group were T2 tumors (3 cm and cm) but only of LRRs in no-RT group was...

Ngày tải lên: 09/08/2014, 09:20

... be defined in current and future clinical trials In Canada, a clinical trial is underway evaluating linac based IMRT and helical tomotherapy, clinically assessing a dose regimen of 68 Gy in 25 ... solution to deliver highly conformal pelvic radiation in the setting of nodal location uncertainty due to incomplete nodal mapping or abherent nodal drainage Conclusion Therefore this research study ... that conformal avoidance, as an advanced treatment planning strategy, is a potential solution to deliver highly conformal pelvic radiation in the setting of nodal location uncertainty due to incomplete...

Ngày tải lên: 09/08/2014, 10:21

... therapies involving gemcitabine and other agents, such as axitinib, cisplatin, and fluorouracil are currently being studied [26-28] Our approach to identifying combination partners for gemcitabine involves ... a potential treatment for pancreatic cancer patients The preclinical finding of inhibition of CHK1 as a sensitizing target for gemcitabine is currently being tested in clinical trials Collectively, ... gemcitabine Genes identified as synergistic to gemcitabine in the RNAi kinase screens are shown in red Gemcitabine induced DNA damage results in the phosphorylation and activation of serine/threonine-protein...

Ngày tải lên: 18/06/2014, 15:20

... trypsin After thorough washing, × 105 separated cells suspended in PBS were cytospun on slides and kept at -80°C until staining Immunohistochemistry staining Immunohistochemical staining of nestin ... s, 60°C for min, and finally 95°C for 15 s, 60°C to 95°C for 30 s, and 95°C for 15 s Quantification of the gene of interest was accomplished by measuring the threshold cycles and comparing them ... Ischemia in rats Animal treatments were designed to minimize pain or discomfort in accordance with the current protocols approved by the Chinese Medical Ethical Committee for animal welfare Forty...

Ngày tải lên: 18/06/2014, 16:20

... her radiation in a single fraction before she awakens from surgery Additional potential advantages include delivering the radiation before tumor cells have a chance to proliferate, performing ... radiation oncologist remained in the room during the radiation delivery either wearing lead aprons or standing behind a mobile radiation shield At the completion of the radiation, the balloon and ... handling and disposal In addition, XB increases the number of settings in which radiation can be performed Early clinical reports have shown this technique to be feasible and associated with minimal...

Ngày tải lên: 09/08/2014, 04:21

... complications in patients treated with abdomino-pelvic radiation therapy for ovarian carcinoma Int J Radiat Oncol Biol Phys 1992, 22:847-51 Lindner H, Willich H, Atzinger A: Primary adjuvant whole abdominal ... carcinoma in complete surgical remission after induction chemotherapy: a randomized, controlled, clinical trial comparing whole abdominal radiotherapy, chemotherapy, and no further treatment Int ... was 3.7 ± 0.3 for RA and 13.4 ± 0.1 for IMRT; time for analysis of data: 1.2 ± 0.1 for RA and 5.1 ± 0.6 for IMRT leading to a total time for QA procedures of: 25.6 ± 1.5 minutes for RA with two...

Ngày tải lên: 09/08/2014, 09:20

... grade for a symptomatic finding requiring any form of medical therapy (e.g., compressive sleeve for lymphedema, physical therapy for neuropathy, or long-term use of pain medication); and grade for ... rates for each tumour location were (radiation therapy >50 Gy vs without radiation therapy) : 90% vs 70% for axillary LN metastasis, 80% vs 72% for inguinal LN metastasis and 85% vs 50% for cervical ... without radiation therapy, and without systemic therapy Having four or more involved lymph nodes, extracapsular extension and node size greater than centimetres were our main indications for radiation...

Ngày tải lên: 09/08/2014, 09:20

... Radiotherapy is successful treatment for orbital lymphoma Int J Radiat Oncol Biol Phys 1993, 26:59-66 Chao CK, Lin HS, Devineni VR, Smith M: Radiation therapy for primary orbital lymphoma Int ... chemo-radiotherapy is more judicious for treating intermediate/high grade lymphomas [11] and primary systemic disease [8], at present radiotherapy is the treatment of choice for NHL localized in the ... cavity According to literature [6,8-25], it is possible to obtain local control in the range of 89-100% using radiotherapy in low or moderate doses as 25-36 Gy A summary of findings of some of...

Ngày tải lên: 09/08/2014, 10:20

... demonstrated in table Discussion Brain metastases are the most common form intra cranial tumor accounting significantly more than one- half of brain tumors in adults Because of advanced in the diagnoses ... palliation of brain metastases Final results of the first two studies by the Radiation Therapy Oncology group Int J Radiat Oncol Biol Phys 1980, 6:1-9 Vermeulen SS: Whole brain radiotherapy in the treatment ... developing brain metastases varies according to primary tumor type, with lung cancer accounting for approximately one half of all brain metastases [2] The prognosis of patients with brain metastases...

Ngày tải lên: 09/08/2014, 10:21

... partially compared with findings in the literature [2,3,6] Fast (1-s)-scan helical CT During the fast-scan CT technique for a target moving in/ out and within the imaging plane, a finite but small number ... well-defined volumes, has been investigated experimentally and/or analytically for targets moving freely in a single dimension (longitudinally or transversally) [2,3] Pertinent motion/imaging parameters ... periodic 3D motion In such instances, the targets' cross section and position in the imaging plane varies continuously as it moves into or out of, as well as within, the imaging plane In this study,...

Ngày tải lên: 09/08/2014, 10:21

... Algorithm for determining ART eligibility for 1787 HIV infected individuals using TLCs, Hb and BMI Figure Algorithm for determining ART eligibility for 1787 HIV infected individuals using TLCs, ... threshold for distinguishing which men had low CD4 cell counts If TLCs are to prove to be a viable alternative to using CD4 cell counting in managing HIV-infected individuals in resource-limited settings, ... be useful not only in determining when individuals should initiate ART, but also in monitoring patients on ART There have been few studies on the use of TLCs in monitoring individuals on ART,...

Ngày tải lên: 10/08/2014, 05:20

... Nabiryo C, Coutinho A: Use of WHO clinical stage for assessing patient eligibility to antiretroviral therapy in a routine health service setting in Jinja, Uganda AIDS Research and Therapy 2008, ... importance in the realm of intensified efforts at scaling up access to ART when CD4 T cell counting monitoring is limited in peripheral health centres and there is advocacy for ‘task-shifting’ of ... MM, Nielsen-Saines K, Palombi L: Excessive Early Mortality in the First Year of Treatment in HIV Type 1-Infected Patients Initiating Antiretroviral Therapy in Resource-Limited Settings AIDS Res...

Ngày tải lên: 10/08/2014, 05:22

... 2), the information provided was not sufficiently succinct for a clear cut decision, and therefore"mainstream” answers were based on the remaining questions Page of and for the last working week ... the indications for MC, as it is used today, have not been determined Presently, a research program is being conducted in the Nordic countries trying to illuminate the use of, the indications for, ... definitions for the term"Scandinavian mainstream chiropractic practice” that we applied during our analyses and presentation of data collected in this current study Using these operational definitions,...

Ngày tải lên: 13/08/2014, 14:20

... exciting new possibilities for controlling this disease, which is the second most common cancer among women worldwide Vaccines that protect against HPV infection, if administered prior to initiation ... allowed to set for 10 minutes Then the plates were inverted and incubated at 37°C Plaques would be visible after 6-8 hours The plaques counted and determined the titer in plaque-forming units per ... to the lysates and continued incubation for 15 minutes at 37°C The culture was centrifuged at 11000 × g for 10 minutes at 4°C The supernatant was recovered, 50 μl of chloroform added, and then...

Ngày tải lên: 14/08/2014, 19:22

... changes for head-and-neck patients, including nodal mass shrinkage and patient weight loss during the course of radiation therapy, can occur [28,29] For these cases, repeat CT imaging and re-planning ... registration is needed for this method The registration of different image modalities is widely used in radiotherapy for delineating the region of interests[27] As the registration algorithms in the commercial ... plan re-optimization for certain head-and-neck and brain tumor patients Declaration of competing interests The authors declare that they have no competing interests Hu et al Radiation Oncology...

Ngày tải lên: 09/08/2014, 08:23

... taken into account by a pencil beam algorithm Dose constraints for the spinal cord were set at 45 Gy, V20 (volume receiving >20 Gy) for a single lung at 50%, V25 for both lungs considered as a single ... patients With ongoing practice some 'rules' evolved, breaking some former "taboos" in radiotherapy of lung cancer: Minimizing the dose to the ipsilateral (i.e tumor bearing) lung In many cases the ... Radiation Oncology 2009, 4:30 tinely for lung cancer patients in all stages During the past years, this technique has continuously been evolved with regard to optimizing the procedures for...

Ngày tải lên: 09/08/2014, 10:20

... assessed for lung, esophagus, and skin using the RTOG acute radiation morbidity scoring criteria every week during treatment Late lung toxicity was evaluated with a modified scoring system considering ... hypofractionated radical radiotherapy using 3D planning comes from Wales [14] Using 2-D and 3-D planning, 112 patients clinically staged as I/II, most of them receiving the dose of 50 Gy in 20 daily fractions, ... only scoring used for late lung toxicity (modified from the Common Toxicity Criteria (CTC) version – Lung) No increase in lung symptoms Increase in lung symptoms due to RT but not requiring steroids...

Ngày tải lên: 09/08/2014, 10:21

... This technique can be used in combination with IMRT in conventionally fractionated radiation therapy to potentially improve clinical outcomes for patients Competing interests The authors declare ... to aid in target delineation Gross tumor volume was outlined during inspiration, expiration, and free breathing scanning and Figure Anteroposterior view of fiducial marker placement Jain et al ... of improving radiation treatment accuracy for tumors near the spinal cord Three forms of IGRT for this purpose have been described in the literature: cone-beam CT (CBCT), KV X-ray imaging, and...

Ngày tải lên: 10/08/2014, 23:20

... immunostaining of SCC Page of vivor study, radiation therapy was associated with a 6.3 fold-increase in risk for NMSC (SCC and basal cell carcinoma) Of these cancers 90% occurred within the radiation ... SCC of the nipple following radiation therapy for breast carcinoma were found This result is surprising given the large number of patients undergoing radiation therapy for breast cancer Overall, ... making inconsistent positioning more likely Exposure of the normal nipple tissue to high doses of radiation may result in radiodermatitis, a risk factor for SCC Fortunately, improvements in radiation...

Ngày tải lên: 11/08/2014, 12:20

... breathing during radiation therapy treatment of NSCLC Int J Med Med Sci 2011; 3: 1-6 Al-Mohammed HI Investigation of breathing maneuvers using free breathing and video biofeedback techniques during ... dose using the gamma index Every point measured in these plans agreed to within ±3% acceptability criteria Figure 2: The chart presenting the matrix of isodose line chamber readings failing the ... depth in the phantom using mm pixel-dose grid resolution, and the point dose was calculated at the isocenter; whereas the reference point was mm behind surface The individual fields are radiated in...

Ngày tải lên: 25/10/2012, 10:51