3 assessing the quality of a meta analysis

... met to establish consensus If relevant data were missing or unclear from a particular trial, we attempted to contact the primary author of that study Statistical analysis Meta- analysis was performed ... by a Scholar Award from the Michael Smith Foundation for Health Research, a New Investigator Award from the BC Lung Association and CIHR, and a Departmental Scholar Award from the University of ... used may have resulted in varying concentrations of surfactant reaching the damaged alveoli and altering the effectiveness of therapy It has been shown that the relative rate of pulmonary deposition...

Ngày tải lên: 12/08/2014, 23:22

... indicators of the components of the quality of prenatal care used in the Jordan Prenatal Care Study3 Figure 1: Examples of the components, sub-components and indicators of quality of prenatal care ... manuscript The MEAwards Program of the Population Council has provided grants to the Jordan and Tunisia studies VI ABSTRACT The paper offers a broad definition of quality of care, presents a comprehensive ... ASSESSING THE QUALITY OF REPRODUCTIVE HEALTH SERVICES No Raeda Al-Qutob, MD, DR.PH Maternal and Child Health Salah Mawajdeh, MD, DR.PH Health Policy and Management Laila Nawar, Ph.D Demography...

Ngày tải lên: 14/03/2014, 15:20

... ensure the suitability of its advice regarding the Funds (January 2011) ‘Barclays failed to take reasonable care to ensure the suitability of its advice.’ The Balanced Fund was risk-rated ‘balanced’ ... mentioning the potential for losses.20 Example of an adviser using a sales aid in a misleading way The adviser used an investment sales aid as part of the risk-profiling process to show the customer the ... advice, we had concerns with the quality of advice in the other quarter In 11% of mystery shops we felt the advice was unsuitable for the customer and in a further 15% the adviser did not gather...

Ngày tải lên: 16/03/2014, 17:20

... replaced the multiplicity of occupational pay grades, pay points and salary scales that had characterized the Whitley system Table 2: Key elements of Agenda for Change: pay bands (April 2006) Pay ... consistent approach to costing, provides one example of the relative lack of detailed evaluation of impact of Agenda for Change Many managers also reported that the additional funding provided had not ... cover the estimated cost of implementation At national level the absence of any full evaluation of implementation of Agenda for Change has limited an assessment of its costs and benefits Of the...

Ngày tải lên: 18/06/2014, 17:20

... statistical analysis UB prepared the first draft of the manuscript and PO and LK made significant contributions to the final draft All authors read and approved the final manuscript Botha et al ... patients dropped out during the course of the study Statistical Analysis All data were entered into a single, electronic database Statistical Analysis was done with Statistica version software ... was required The majority of contacts (>50%) were in the community, mainly in the form of home visits The team was based at Stikland Hospital This held both advantages and disadvantages On the...

Ngày tải lên: 11/08/2014, 16:22

... and editing the manuscript; PW and MW were involved in the writing and editing of the manuscript and responsible for the searches of the databases and the statistical analysis All authors read ... from a meta- analysis of randomized, controlled clinical trials is usually considered the most influential in management guidelines because of the large number of patients involved This meta- analysis ... trial of at least 12 weeks duration 2) Data was available on at least one of the specified endpoints (withdrawal rate, moderate/severe exacerbations, pre-bronchodilator FEV1 and health status)...

Ngày tải lên: 12/08/2014, 16:20

... prevent any further degradation In the case of database samples, a physical sample of the offender’s DNA must be kept in the laboratory indefinitely in case a database hit ever occurs and the sample ... 20 Statistical analysis of the results of average peak height, peak height ratios, imbalanced peak height ratios, and A was performed using one-way fixed-effect analysis of variance (ANOVA) tests ... calculated by taking the average of all called true alleles across all loci from all samples at each peak location Peaks were called as having peak height imbalance when the ratio was less than the expected...

Ngày tải lên: 24/08/2014, 12:30

... subdomains (see Tables 4, for the loadings) The factor analysis was based on baseline data only The first factor of the 12-factor solution mainly consists of items from the subdomains IRA and TA, ... domain often load together on one factor It is therefore advisable to use the sub-domains rather than the domains of the CHIPCE when evaluating ADHD patients This is supported by the factor analysis ... Montoya A, Hervas A, Cardo E, Artigas J, Mardomingo MJ, Alda JA, ´ Gastaminza X, Garc a- Polavieja MJ, Gilaberte I, Escobar R (2009) Randomized controlled trial of atomoxetine first-line treatment of...

Ngày tải lên: 12/02/2014, 19:20

... The Performance of SRI Funds: A Meta- Analysis   The Performance of Socially Responsible Investment Funds: A Meta- Analysis Sebastian Rathner* March 2012 Abstract Empirical studies, which analyse ... domicile of the funds) Australia Belgium Canada Europe France Germany Germany/Austria/Switzerland International Ireland Italy Japan Luxembourg Malaysia Netherlands Norway Singapore Sweden Switzerland ... include the performance evaluation models as control variables in the meta- analysis Benson et al (2006) compare the annual raw returns and sharp ratios of US funds They not report any significant...

Ngày tải lên: 30/03/2014, 12:20

... 2):S190-195 18 Baena AV, Allam MF, Del Castillo AS, Diaz-Molina C, Requena Tapia MJ, Abdel-Rahman AG, Navajas RF: Urinary bladder cancer risk factors in men: a Spanish case-control study Eur J Cancer Prev ... design, data extraction, statistical analysis, manuscript drafting and editing JY and QM participated in the literature research, manuscript drafting and editing SS participated in design and data extraction ... 20 Garcia-Closas R, Garcia-Closas M, Kogevinas M, Malats N, Silverman D, Serra C, Tardon A, Carrato A, Castano-Vinyals G, Dosemeci M, et al: Food, nutrient and heterocyclic amine intake and the...

Ngày tải lên: 09/08/2014, 02:21

... interpretation of the data and helped to draft the manuscript SS performed the meta- analysis, participated in the evaluation of studies for inclusion, and helped to draft the manuscript All authors read and ... exception, an SIR of 1.68, was in a Japanese population and the authors state that they observed a generally higher risk of malignancies in Japanese women with RA than that reported in comparable Caucasian ... cases, there was considerable variation in the calculated SIRs among the individual studies for site-specific malignancies Nevertheless, the random effects meta- analysis demonstrated an overall pattern...

Ngày tải lên: 09/08/2014, 10:23

... and meta- analysis of all randomised controlled trials (RCTs) of pharmacological and non-pharmacological treatments that are available in standard primary care settings and those that are administered ... fibromyalgia when comparing primary care and specialised care Our meta- analysis demonstrates that there are no differences in the overall outcome of fibromyalgia regardless of the level of care ... Arthritis Research & Therapy Vol 10 No Garcia-Campayo et al no clear consensus on the treatment of choice and fibromyalgia remains relatively refractory to treatment A number of meta- analyses...

Ngày tải lên: 09/08/2014, 10:23

... Data source The databases of PubMed, Wanfang Data, as well as American Society of Hematology (ASH) and American Society of Clinical Oncology (ASCO) annual meeting abstracts were searched for articles ... Saito K, Nakamura Y, Aoyagi M, Waga K, Yamamoto K, Aoyagi A, Inoue F, Arai Y, Tadokoro J, Handa T et al: Low-dose cytarabine and aclarubicin in combination with granulocyte 18 colony-stimulating ... refractory anemia with excess blasts in transformation Int J Hematol 2000, 71(3):238-244 39 Hirayama Y, Sakamaki S, Takayanagi N, Tsuji Y, Sagawa T, Chiba H, Matsunaga T, Niitsu Y: Chemotherapy...

Ngày tải lên: 10/08/2014, 21:23

... rituximab may provide important data in the field of the best induction in patients with follicular lymphoma An unavoidable weakness of any meta- analysis is its inability to perform multivariate analyses ... first analysis (frontline treatment alone) Outcome The primary goal of the analyses was to compare the response rates of R-CVP and R-CHOP in the treatment of patients with FL as frontline therapy ... early stage (Ann-Arbor stages I and II) and late stage (Ann-Arbor stages III and IV) Combining the studies, there were 439 patients, and over 98% of these were late-stage Treatment efficacy The...

Ngày tải lên: 10/08/2014, 22:20

... but also generalisable to other healthcare settings The use of a theoretical framework to underpin the diagnostic analysis has resulted in the collection of a far broader range of data than if a ... opinion leaders : effects on professional practice and health care outcomes The Cochrane Database of Systematic Reviews 2005:4 Armenakis AA, Bedeian AG: Organizational change: a review of theory and ... Christian S: Achieving change in health care practice Journal of Evaluation in Clinical Practice 2003, 9:225-238 Armenakis A, Bedeian A: Organizational change: a review of theory and research in the...

Ngày tải lên: 11/08/2014, 05:22

... an artefact of the particular social class measure is debatable Quality of life differs markedly between ethnic groups, even after adjusting for the predictors listed above The standard deviations ... groups in terms of self-reported importance of various aspects of quality of life A regression model of each total quality of life scale revealed greater unexplained variability in the White British ... between ethnic groups that are consistent across the three scales and are not explained by a battery of predictor variables If scales such as these are used to compare quality of life between ethnic...

Ngày tải lên: 11/08/2014, 23:22

... group The source of the publication was also classified as to whether the publication was in a critical care journal or a journal that primarily dealt with another area of medical practice Analysis ... Analysis The primary analysis of the data was descriptive The proportion of reports that met each of the criteria was determined and tabulated The estimated mean overall quality summary score was calculated ... found that the quality of the meta- analyses in the critical care literature was comparable to the quality of reviews published in the emergency medicine [17], the anaesthesia [19] and the general...

Ngày tải lên: 12/08/2014, 22:22

... cost-effectiveness analysis was not performed in the studies included in this meta- analysis Based on the baseline risk of candidaemia of 4.5% in the placebo arm of this meta- analysis, the number of patients ... Oxford, UK) database for further analyses The hospital mortality and the proportion of patients with candidaemia were chosen as the main outcomes of this metaanalysis because they are the most specific ... candidaemia rate of 4.5% in the placebo arm of this metaanalysis is consistent with the estimated risk of candidaemia in patients with at least one risk factor for candidaemia The risk factors include...

Ngày tải lên: 12/08/2014, 23:20

... [9-12] These trials have yielded conflicting results Hence, we conducted a meta- analysis of available clinical trials to evaluate the efficacy of oral chlorhexidine application on the incidence of ... results of this meta- analysis suggest that the incidence of NP and rate of mortality are not reduced by administration of the oral antiseptic agent chlorhexidine Of the four trials that were ... out of 50) of the total isolates The distribution of these isolates was comparable among the two groups (46% A review of studies that have examined oral and lung colonization have shown that changes...

Ngày tải lên: 12/08/2014, 23:21

... meta- analysis Data extraction The data extracted from the articles for further analysis were the study population, the dosage and the duration of the administered drugs, the number of clinically ... performing a meta- analysis of comparative trials studying the effect of the administration of antibiotics via the respiratory tract on the colonization of the respiratory tract by bacteria and development ... Clin Trials 1986, 7:177-188 Mantel N, Mocarelli P, Marocchi A, Brambilla P, Baretta R: Stratified analysis of multivariate clinical data: application of a Mantel-Haenszel approach Stat Med 1983,...

Ngày tải lên: 13/08/2014, 03:20