... pathway for hyperosmolarity adaptation in budding yeast (Saccharomyces cerevisiae) and based on the related mRNA expression time-series data from Stanford Microarray Databases Results Inferring the ... kinases, a MAP kinase (MAPK), a MAPK kinase (MAPKK) and a MAPKK kinase (MAPKKK), are common signalling modules in eukaryotic cells [20,21] The budding yeast (S cerevisiae) has several MAPK cascades ... intervention of other nodes or parameters Sontag et al [15] have proposed another complementary method based on time-series measurements, which can be useful when stationary data are not available and the...
... between Arg56 and the O2 ofthe nucleobase However, after evaluating both crystal structures we conclude that the alternative orientation ofthe base and sugar–phosphate backbone ofthe nucleotide ... that the first three b strands may form association interfaces that promote aggregate growth In the late stage of amyloid formation, signals from the N-terminal half ofthe molecules (equivalent ... from a different chain and vice versa The swapped chains can be interrelated by a noncrystallographic twofold rotation axis The functional units align well with the structures ofthe two models of...
... log as the most up to date ‘‘truth’’ about the state ofthedata on disk The main difference is that database systems not use the log as the final repository for data: a separate data area is reserved ... purpose The separate data area of these database systems means that they not need the segment cleaning mechanisms ofthe Sprite LFS to reclaim log space The space occupied by the log in a database ... modeled The simulator runs until all clean segments are exhausted, then simulates the actions ofa cleaner until a threshold number of clean segments is available again In each run the simulator...
... 5.1 Variation of global solar radiation and ambient temperature The year round global solar radiation and ambient temperature data for Chennai is taken from [34] Figure shows the variation of global ... Al-Abbasi M .A. , Al-Karaghouli A. A., Minasian A. N Photochemically assisted solar desalination of saline water Desalination 1992, 86(3), 317–324 [4] Mowla D, Karimi G Mathematical modeling of solar still ... condensation The outlet temperature from the flat plate collectors, latent heat and refined latent heat of vaporization of water from each stage and specific heat capacity of water from each stage are averaged...
... for the syntactic structure of language, it prefers placing the function of language as central (what language does and how language does it) rather than placing the elements of language and their ... grammar are different from formal models of grammar by their focus on the communicative aspect of language 2.4 Metafunctions Halliday developed a theory ofthe fundamental functions of language ... writer playing the role as recounter - Kumiko Tsuchida, the railway guard, the police, and the Japanese embassy Mode: Mood: declarative Modality: ability ofthe main character on the past - Medium...
... declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative ... declarative declarative declarative declarative declarative declarative declarative declarative imperative declarative declarative Modality ability/neg ability/pos ability/neg ability/neg ability/neg ... Subject The spaceship The planet They There The spaceship The two astronauts The woman It She We It Both of them They All plants and Animals They They Everything The man Nothing Something He I The...
... neutral and alkaline pH; PhyH-DII was less stable under the same conditions (Fig 2D) PhyH was basically stable at 35 °C, and retained 60% ofthe initial activity at 45 °C for 90 when assayed at ... another single-domain phytase may improve the catalytic efficiency ofthe latter Materials and methods Strains, plasmids and chemicals E coli Trans1-T1 (TransGen, Beijing, China) and pGEM-T Easy ... sum of PhyH-DI and PhyH-DII and two times greater than that of PhyHDII This large variance cannot be ascribed to the function of PhyH-DI alone The dual-domain phytase was shown to be a dimer according...
... the war was the impact ofa major hurricane that affected East Pakistan The apathy ofthe West Pakistani leadership and their failure to aid East Pakistan only aggravated an already tense situation ... 1948, Dhaka and Urdu were declared West Bank might claim that the Bangladesh Liberation theof cial languages of all of Pakistan This proved War and the secession of East Pakistan was the result ... down theof ces ofthe pan-Arab Al have by facilitating the spread of Gaza’s lawlessness into the West Bank and ultimately to Israel Masked Fatah gunmen have occupied various PA fence, since large...
... optimization The half-height widths ofthe NMR signals were used as a measure ofthe uncertainty of each NMR data point and an experimental uncertainty of 2% was assumed for the experimental points ofthe ... because these are the most distant pair of haems in the structure and are therefore expected to have the weakest interaction [33] The pH dependence ofthe chemical shifts ofthe NMR signals ofthe ... thermodynamic model to the NMR data (for the case of DvHc3:ZnRb), or to the NMR and UV-visible data sets simultaneously (for the case of DvHc3:Pi) using the Marquardt method for parameter optimization...
... Proxies If data was not availHigh Level able to be pulled, the calling I/O Facade would need to block I/O Facade I/O Facade I/O Facade Abstraction awaiting a result In order for the I/O Facade to ... pull, the system must allocate additional threads to allow the application to make progress while the I/O Facade task is blocked However, 2: Demarshaled data adding threads to the system has many ... data from a sensor is given to an appropriate Sensor Proxy Each Sensor Proxy object demarshals the incoming data and notifies I/O Facade objects that depend on the sensor’s data Since modern aircraft...
... state B, active state above pH 6.3 side-chain at residue 210 is dispensable, as shown by the fact that H21 0A and H210S are as active as native API with VLK-MCA as a substrate (Table 1) This means ... by the Trp169–His210 stacking, suggesting that API has a catalytic quadruple apparatus, composed of Ser194, His57, Asp113 and His210, rather than a catalytic triad ACKNOWLEDGEMENT We are grateful ... aspartate in the catalytic triad is not fully understood because several serine proteases not have an aspartate as the catalytic apparatus M NaCl However, for chymotrypsin-type serine proteases,...
... Annals of Mathematics, 159 (2004), 1247–1274 Numerical characterization ofthe K¨hler cone ofa compact K¨hler manifold aa By Jean-Pierre Demailly and Mihai Paun Abstract The goal of this ... there exists a very neat characterization of nef classes on arbitrary surfaces, K¨hler or not aThe Main Theorem has an important application to the deformation theory of compact K¨hler manifolds, ... can also view this fact as a characterization ofthe dual cone ofthe nef cone, in the space of real cohomology classes of type (n − 1, n − 1) This leads immediately to Corollary 0.4 In the case...
... that factor Xa cleaved and activated proHP8Xa When activated HP8Xa was mixed with proSpatzle¨ 1A, the 38 kDa pro-Spatzle band disappeared, and a ¨ 12 kDa product was produced (Fig 7A) N-terminal ... analysis using antiserum against M sexta HP8 Bands representing the proHP8Xa zymogen, a truncated form of proHP8Xa and the catalytic domain of active HP8 are marked with arrowheads The size and ... exchange chromatography SDS ⁄ PAGE analysis in the presence of b-mercaptoethanol indicated that the purified Spatzle had an ¨ apparent molecular mass of 38 kDa, which is slightly larger than that...
... et al Crystal structure of salt-tolerant glutaminase A B Fig L-Glutamate in complex with Mglu and asparaginase of Erwinia carotovora LGlutamate (cylinder) on the surfaces ofthe structures of ... significant conformational change upon the binding of ligand [31] The smaller size of l-glutamine than the substrates for b-lactamase could be one ofthe reasons for the conformational changes ofthe ... a Backbone atoms ofthe N-terminal domains (1-305 aa) in the T and TG structures are aligned b Backbone atoms of Bacillus glutaminase are superimposed on those ofthe liganded enzyme c The value...
... Another insider installs a keystroke logger to get a few passwords to another computer in the same office • A database administrator makes an extra copy ofthe database files, but says the tapes ... for the development of such datasets include a MITRE dataset of normal, and “insider threat” network activities; data from the ARDA NIMD4 study; data obtained from use ofthe Glass Box5 software; ... Breakout sessions considered what databases would aid in this research if they were available Researchers need databases containing examples of specific attacks, the characterization of normal...
... YGR287c The sequence data for isomaltase is available from the DNA Data Bank of Japan with accession number AB109221 The entire coding region ofthe insert was amplified by PCR and subcloned into the ... II of maltase is the catalytic nucleophile Because the Asp214 of maltase is equivalent to the Asp215 of isomaltase, a mutant with the residue altered to Ala was tested for its activity on a- pNPG ... recombinant enzymes reacted with antisera against native maltase and isomaltase, the recombinant enzymes showed the same dose–response as the native enzymes by antiserum neutralization (data not...
... − 7a − 3a From take 2a 5a − 3a To add 2a − 5a − 3a From take − 4a To − 4a − 3a add 3a aaThe principle is clear; namely, The subtraction of any number gives the same result as the addition of that number ... remain in the tank at the end of five days? 18 Two men are 150 miles apart, and approach each other, one at the rate of x miles an hour, the other at the rate of y miles an hour How far apart ... number of apple trees How many are there of each kind? John and Mary gathered 23 quarts of nuts John gathered quarts more than twice as many as Mary How many quarts did each gather? To the double of...
... PIVceeding ofthe ACM SIGMOD Conference on Management of Data, May 1994 [CS92] RakeshChandmand Arie Segev.ManagingTemporalFinancial Data in anExtensible Database.In Proceedings ofthe International Conference ... supports relational data as well as sequencedata, using a novel design paradigm of enhancedabstractdata types (BADTs ) The systemimplementation basedon this paradigmallows sequence relational queriesto ... array and list constructs that allow collections ofdata to be ordered The object-relational database systemIllustra [I11941 provides database support for time-seriesdata along with relational...
... sequence was 5¢-GGAGTCTAATGGACAACTTTNNNTGGATGGA GGGTTATATTGAGCG-3¢, with GAC, CAA and TCA as mutated codons for E451D, E451Q and E451S, respectively DNA sequencing was used to confirm the incorporation ... affected by the exchange ofa charged participant (carboxyl group ofthe E side-chain) for an uncharged participant (amide group ofthe Q side-chain) Otherwise, the replacement of E451 with D and S ... ÔeÕ stands for an equatorial hydroxyl and a for an axial one Therefore, the interaction between any residue at position 39 and an equatorial 4-OH was called /4e, and between any residue at position...