2 transport and pharmacokinetics of vc in human subjects

Báo cáo khoa học: "INTEGRATING MULTIPLE KNOWLEDGE SOURCES FOR DETECTION AND CORRECTION OF REPAIRS IN HUMAN-COMPUTER DIALOG*" potx

... Furthermore, in cases where Gemini detected a repair, it produced the intended correction in 62 out of 68 cases for syntax alone, and in 60 out of 64 cases using combined syntax and semantics In both ... vowel and ended in a consonant, and 12 contained no vocalic portion Fragments A third way in which acoustic knowledge can assist in detecting and correcting repairs is in the recognition of word ... 19 -22 , 1991, pp 20 0 -20 3 Shriberg, E., Bear, 3., and Dowding, J (19 92 a) "Automatic Detection and Correction of Repairs in Human- Computer Dialog" Proceedings of the DARPA Speech and Natural Language...

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Báo cáo hóa học: " Nutraceutical augmentation of circulating endothelial progenitor cells and hematopoietic stem cells in human subjects" potx

Danh mục: Hóa học - Dầu khí

... Granulocyte-macrophage colony-stimulating factor to harvest circulating 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 haemopoietic stem cells for autotransplantation Lancet 1989, 2( 8663):580-5 Leone AM, ... a peak increase of approximately 53% in the number of CD34 expressing cells and and a 90% increase in CD133 cells in circulation Furthermore, a significant augmentation of cells possessing hematopoietic ... results in a 58-fold increase in granulocytic progenitors and 24 -fold increase in erythroid progenitors [ 62] , which approximately correlated with CD34 counts [63] Maintaining such extreme levels of...

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Molecular transport and structure of DNA in a congested state

Danh mục: Cao đẳng - Đại học

... Superhelical density determination 24 26 iii 2. 3 Small angle neutron scattering 29 2. 3.1 Background 29 2. 3 .2 Interpretation of scattering intensity 31 Reference 36 Chapter Viscoelasticity of entangled lambda ... 17 2. 1 Preparation of plasmid DNA pHSG298 17 2. 1.1 Isolation of Deuterated DNA 17 2. 1 .2 Isolation of Hydrogenated DNA 18 2. 1.3 Purification by chromatography 19 2. 2 Plasmid characterization 2. 2.1 ... of the supporting medium provides different screening conditions of DNA From a biophysical point of view, it is of interest to understand the interplay between conformation and interactions in...

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Báo cáo khoa học: Transport of L-arginine and nitric oxide formation in human platelets pdf

Danh mục: Báo cáo khoa học

... absence of Na , conﬁrming the presence of the system y+L in human platelets (Fig 2) Data indicate that platelet L-arginine transport mainly Fig L-Arginine uptake in the presence or absence of Na+ in ... Autelitano, D.J & Chin-Dusting, J.P (20 00) In vivo and in vitro evidence for impaired arginine transport in human heart failure Circulation 1 02, 27 07 27 12 41 Mykkanen, J., Torrents, D., Pineda, M., Camps, ... N-ethylmaleimide inhibited L-arginine uptake in a dose-dependent manner and at 20 0 lM produced the maximal inhibition, that Ó FEBS 20 03 Arginine transport and NO formation in platelets (Eur J Biochem 27 0) 20 07...

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Báo cáo sinh học: "Safety and pharmacokinetics of recombinant human hepatocyte growth factor (rh-HGF) in patients with fulminant hepatitis: a phase I/II clinical trial, following preclinical studies to ensure safety" ppt

Danh mục: Hóa học - Dầu khí

... a single dose of rhHGF Page of 12 The secondary endpoints were the pharmacokinetics of intravenously injected rh-HGF and clinical efficacy, including survival period and outcome To examine pharmacokinetics ... decrease in BP during rh-HGF infusion and renal toxicity induced by repeated rh-HGF dosing, including an increase in urinary excretion of albumin, were potential adverse events in a human study In ... http://www.translational-medicine.com/content/9/1/55 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 cyclins in rat hepatocytes Biochem Biophys Res Commun 20 01, 28 0:368-373 Hasuike S, Ido...

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Báo cáo khoa học: "The conformation change of Bcl-2 is involved in arsenic trioxide-induced apoptosis and inhibition of proliferation in SGC7901 human gastric cancer cells" doc

Danh mục: Báo cáo khoa học

... Wenzhou 325 000, China and 4Department of Internal Medicine, The First Affiliated Hospital of Wenzhou Medical College, Wenzhou 325 000, China 18 20 21 22 Received: December 20 09 Accepted: 20 April 20 10 ... resulting in exposure of its BH3 domain [21 ,22 ] It was also reported that paclitaxel could directly target Bcl -2 in the loop domain, mimics activity of Nur77, thereby facilitating the initiation of ... (As2O3) in endometrial carcinoma cells Gynecol Oncol 20 07, 105(1) :21 8 -22 2 Kang MH, Reynolds CP: Bcl -2 inhibitors: targeting mitochondrial apoptotic pathways in cancer therapy Clin Cancer Res 20 09,...

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Báo cáo y học: "Functional genomics analysis of low concentration of ethanol in human hepatocellular carcinoma (HepG2) cells. Role of genes involved in transcriptional and translational processes"

Danh mục: Y học thưởng thức

... Large-scale gene profiling of the liver in a mouse model of chronic, intragastric ethanol infusion J Hepatol 20 04;40 :21 9 -27 Int J Med Sci 20 07, 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 Seth D, Leo ... cells Probeset 20 2757_at 20 4990_s_at 20 422 6_at Gene symbol COBRA1 ITGB4 STAU2 20 9377_s_at HMGN3 20 6385_s_at ANK3 Gene title cofactor of BRCA1 integrin, beta staufen, RNA binding protein, homolog ... of ethanol per se or enhanced intestinal translocation of bacterial toxins induced by ethanol? Alcohol Clin Exp Res 20 05 ;29 :166S-71S 44 Fukui H Relation of endotoxin, endotoxin binding proteins...

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RESEARCH ON THE CHANGE OF 2-AP AND OTHER VOLATILE COMPOUNDS IN PROCESSING BUN FROM RICE

Danh mục: Sinh học

... 400C to 22 00C at a rate of 30C/min and finally maintained at 22 00C for min; - For SPME: from 40°C to 115°C at a rate of 3°C/min then from115°C to 22 0°C at 30°C/min and finally maintained at 22 0◦C ... retention time (Rt) of collidine and 2- AP in pandan were detected at 12. 936 minute and 9.498 minute respectively wherein this 2- AP will be used as a standard to identify and quantify 2- AP in aromatic ... (Table 2) Table Peak areas of collidine and 2- AP in pandan leaves recorded by GC-FID and GCMS Samples Peaks’areas (pA*s) Collidine 14009069 2- AP in young pandan leaf 581578 62 2-AP in mature pandan...

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Báo cáo khoa học: Alternative splicing: role of pseudoexons in human disease and potential therapeutic strategies pot

Danh mục: Báo cáo khoa học

... splicing code RNA 14, 8 02 813 12 Hertel KJ (20 08) Combinatorial control of exon recognition J Biol Chem 28 3, 121 1– 121 5 13 Cartegni L, Chew SL & Krainer AR (20 02) Listening to silence and understanding ... intron gain Proc Natl Acad Sci USA 105, 722 3– 722 8 21 Zhang XH, Arias MA, Ke S & Chasin LA (20 09) Splicing of designer exons reveals unexpected complexity in pre-mRNA splicing RNA 15, 367–376 22 Rodriguez-Trelles ... Wilton SD (20 09) Characterization of a complex Duchenne muscular dystrophy-causing dystrophin gene inversion and restoration of the reading frame by induced exon skipping Hum Mutat 30, 22 28 42 Lualdi...

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Báo cáo khoa học: Expression of cholinesterases in human kidney and its variation in renal cell carcinoma types pdf

Danh mục: Báo cáo khoa học

... erythrocytes in the extent of binding with the lectins concanavalin A, Lens culinaris agglutinin 4 522 (LCA), and Ricinus communis agglutinin (RCA) (Fig 3), ruled out the blood origin and supported ... amyloid b-peptide and presenilin-1 [20 ], neuronal enolase, the scaffold protein RACK1 and protein kinase C [21 ], the corepressor CtBP [22 ], and Ran-binding protein [23 ] Butyrylcholinesterase can ... cholinesterases in brain and non-brain tumours Chem Biol Interact 157–158, 22 7 23 2 27 Perry C, Sklan EH, Birikh K, Shapira M, Trejo L, Eldor A & Soreq H (20 02) Complex regulation of acetylcholinesterase...

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Báo cáo Y học: Regulation of RAS in human platelets Evidence that activation of RAS is not sufﬁcient to lead to ERK1-2 phosphorylation pot

Danh mục: Báo cáo khoa học

... 62 175 62 83 IP:SHC, WB:P-Y IP:GRB2, WB:SYK 62 47 25 32 kDa kDa 32 IP:SHC, WB:GRB2 IP:GRB2, WB:P-Y IP:GRB2, WB:LAT 25 kDa 25 IP:GRB2, WB:GRB2 kDa IP:GRB2, WB:GRB2 Convulxin and TPO induce GRB2 ... using GST fusion protein containing the RAS-binding domain of RAF Precipitated proteins were resolved by 12. 5% SDS/PAGE and analysed by Western blotting using an anti-RAS Ig (top) Proteins of ... links of the pathway For instance, MP1 can bind MEK and ERK1 supporting ERK1 activation [26 ], and kinase suppressor of RAS can bind RAF, MEK and ERK favouring activation of MEK and ERK1 -2 through...

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Báo cáo khoa học: Characterization of rat cathepsin E and mutants with changed active-site residues and lacking propeptides and N-glycosylation, expressed in human embryonic kidney 293T cells ppt

Danh mục: Báo cáo khoa học

... Yamamoto K (1999) Role of N-glycosylation in cathepsin E: a 22 8 16 17 18 19 20 21 22 23 24 25 26 27 28 comparative study of cathepsin E with distinct N-linked oligosaccharides and its nonglycosylated ... essential for the processing and maturation of this protein FEBS Journal 27 3 (20 06) 21 9 22 9 ª 20 05 The Authors Journal compilation ª 20 05 FEBS 22 1 Recombinant cathepsin E and its mutants T Tsukuba ... Cathepsin E and cathepsin D In Protease: New Perspectives (Turk V, ed.), pp 59–71 Birkhauser, Switzerland FEBS Journal 27 3 (20 06) 21 9 22 9 ª 20 05 The Authors Journal compilation ª 20 05 FEBS 22 7 Recombinant...

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Báo cáo Y học: Monitoring the structural consequences of Phe12 ﬁ D-Phe and Leu15 ﬁ Aib substitution in human/rat corticotropin releasing hormone Implications for design of CRH antagonists pdf

Danh mục: Báo cáo khoa học

... Gravanis, A & Cordopatis, P (20 01) Synthesis and biological evaluation of new h/rCRH peptide 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 analogs In Peptides 20 00 (Martinez, J & Fehrentz, J.-A., ... spectra were acquired using a spectral width of 6410 .26 Hz (10.7 p.p.m) and consisted of 20 48 data points in the F2 dimension, 16– 32 transients and 720 –1 024 complex increments in the F1 dimension ... Cc2 Val18 and HN and Cb Ala 22 protons have been observed This distortion of the linear structure of human/ rat CRH [15] in the region of Aib residue probably acts as a helix-breaking signal in...

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BÁO CÁO "RESEARCH ON THE CHANGE OF 2-AP AND OTHER VOLATILE COMPOUNDS IN PROCESSING BUN FROM RICE" doc

Danh mục: Báo cáo khoa học

... 400C to 22 00C at a rate of 30C/min and finally maintained at 22 00C for min; - For SPME: from 40°C to 115°C at a rate of 3°C/min then from115°C to 22 0°C at 30°C/min and finally maintained at 22 0◦C ... retention time (Rt) of collidine and 2- AP in pandan were detected at 12. 936 minute and 9.498 minute respectively wherein this 2- AP will be used as a standard to identify and quantify 2- AP in aromatic ... (Table 2) Table Peak areas of collidine and 2- AP in pandan leaves recorded by GC-FID and GCMS Samples Peaks’areas (pA*s) Collidine 14009069 2- AP in young pandan leaf 581578 62 2-AP in mature pandan...

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Transport and fate of persistent toxic organic chemicals in aquatic ecosystems: the Niagara River to St Lawrence River Estuary example pptx

Danh mục: Tự động hóa

... primarily of inorganic material and have an organic carbon content of only some % or less However, some of this organic content can be in the form of thin organic coatings on the mineral substrates In ... largest remaining mass not transported downstream, volatilized/or degraded, is in bottom sediments Bottom sediments of lakes and impoundments are often major sinks and sites of eventual burial of PTOCs ... are involved The areas of highest concentrations reflect these sources and in- lake processes of sediment focusing Lake sediment cores can be analyzed to determine changes in historical inputs of...

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Báo cáo khoa học: Expression of heme oxygenase-1 is repressed by interferon-c and induced by hypoxia in human retinal pigment epithelial cells pot

Danh mục: Báo cáo khoa học

... Role of IFN-c-induced indoleamine 2, 3dioxygenase and inducible nitric oxide synthase in the replication of human cytomegalovirus in retinal pigment epithelial cells J Immunol 1 62, 957–964 Nagineni, ... HO-1 in human RPE cell lines In contrast to interferon-c, hypoxia induced the expression levels of HO-1 mRNA in D407 cells and exerted no or only marginal effects in ARPE-19 cells (Fig 2) In D407 ... 24 -h incubation and harvested The amounts of DNA used for transfection were lg of a test fusion gene and 20 ng of an internal control, pRL-TK, containing the herpes simplex virus thymidine kinase...

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A Review of Transport and Urban Air Pollution in Pakistan: SYED ZAFAR ILYAS ppt

Danh mục: Điện - Điện tử

... 1(metros) 3(rest of country) ND ND ND ND ND 42 NA 2. 1 2. 2 2. 2 2. 7 30 30 32 32 40 SYED ZAFAR ILYAS 21 A Review of Transport and Urban Air Pollution… g/m3, max Engine intake system Cleanliness Sulfur, ... by mass, max Gasoline 20 00 20 05 0. 12 0.13 1990 0.60 1995 0.16 Proposed 0.005 0 .23 0 .20 in low leaded gasoline 0 .20 in low leaded gasoline 0.015 32- 62 32- 60 60 1(metros) 3(rest of country) ND Reid ... Cars, M2W Others Total jeeps, vehicles motor taxis vehicles 1975 0 .22 0 0.05 0 .28 0 0.05 0.110 0.71 1985 0.600 0.16 0.86 0 .28 0.1 92 2.0 92 1995 3.50 1. 32 3.60 6.3 1 .20 0 15. 92 2005 4.00 2. 10 8 .29 20 .50...

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Báo cáo Y học: Expression of glucose transporter-2, glucokinase and mitochondrial glycerolphosphate dehydrogenase in pancreatic islets during rat ontogenesis potx

Danh mục: Báo cáo khoa học

... with 20 mM glucose and actinomycin D Ó FEBS 20 02 GLUT -2, glucokinase and mGDH during development (Eur J Biochem 26 9) 123 required for the synthesis of new proteins involved in the transcription of ... FEBS 20 02 Fig Ontogenesis of hexokinase I and glucokinase protein in rat pancreatic islets and liver Western-blot analyses of glucokinase in pancreatic islets (A) and liver (B) and hexokinase I in ... expression of GLUT -2 and glucokinase mRNA and protein in the pancreatic islets of fetal and adult rats We studied the effect of glucose concentration (2. 8, 5.5 and 20 mM) on GLUT -2 mRNA expression and...

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Báo cáo sinh học: " Roles of adjuvant and route of vaccination in antibody response and protection engendered by a synthetic matrix protein 2-based influenza A virus vaccine in the mouse" pdf

Danh mục: Hóa học - Dầu khí

... influenza A virus Vaccine 1999, 17 :22 37 -22 44 Page 12 of 14 (page number not for citation purposes) Virology Journal 20 07, 4:118 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 Liu W, ... antigenic peptide vaccine that contains ectodomains of matrix protein Vaccine 20 03, 21 :26 16 -26 26 Slepushkin VA, Katz JM, Black RA, Gamble WC, Rota PA, Cox NJ: Protection of mice against influenza A virus ... H, Kurata T, Tamura SI: Induction of innate immunity by nasal influenza vaccine administered in combination with an adjuvant (cholera toxin) Vaccine 20 00, 18 :27 13 -27 22 Rudent A, Zalisz R, Quero...

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