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Báo cáo sinh học: "Characterization of the ribonuclease activity on the skin surface" ppsx
... from the University of Tübingen BS and SP are supported by the Fritz Bender Stiftung 26 References 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 Tabachnick J, Freed R: Demonstration of Nucleases on ... structure ribonuclease activity Impact of athe skin surfaceat the 5'end of the substrate Impact of a Cap structure at the 5'end of the substrate mRNA on the skin surface ribonuclease activity Ribonuclease ... not contain a dominant 5'-exonuclease activity or these enzymes can recognize equally well capped and non-capped mRNA The ribonuclease activity on the skin surface is not dominantly of the exonuclease...
Ngày tải lên: 14/08/2014, 19:22
Tài liệu Activity 7.2: Determining the Impact of Technology on a Windows DNA Design docx
... completing the above steps, you will discuss your responses with the class The instructor will write the class consensus on a flip chart Use the space below for brainstorming Activity 7 .2: Determining ... Security After completing the above steps, you will discuss your responses with the class The instructor will write the class consensus on a flipchart THIS PAGE INTENTIONALLY LEFT BLANK ... 50 Activity 7 .2: Determining the Impact of Technology on a Windows DNA Design Exercise 1: Determining Technology Implications ! Determine technology implications Participate in...
Ngày tải lên: 21/12/2013, 06:16
Báo cáo hóa học: " In vivo evidence of htid suppressive activity on ErbB-2 in breast cancers over expressing the receptor" potx
... 2/ 1/1/3 2/ 1/1/3 1 /2/ 0 /2 2/1/0/3 ΔCt 4,68 3, 32 2,77 5,81 4,38 4.08 2, 08 2, 57 ΔΔCt 0,94 -0,43 -0,98 2, 07 0,64 0,34 -1,66 -1,18 0, 52 1,35 1,97 0 ,24 0,64 0,79 3,16 2, 27 52 135 197 24 64 79 316 22 7 ... 54 29 3 28 5 114 165 HER -2 ΔCt 1,63 0,44 0 ,29 -0,11 0,60 -0,69 -1,11 -2, 37 ΔΔCt 3,95 2, 76 2, 61 2, 21 1, 72 1,63 1 ,21 -0,05 0,06 0,15 0,16 0 ,22 0,30 0, 32 0,43 1,04 15 16 22 30 32 43 104 10 11 12 13 ... 14 15 2/ 0/0 /2 1/x/x /2 1 /2/ 0/3 3/1/x/3 4 /2/ 0/3 4 /2/ 0/3 3/4/0/3 ΔCt 3,47 3,43 4,08 0,68 3,44 3,89 2, 08 ΔΔCt -0 ,28 -0,31 0,34 -3,06 -0,31 0,15 -1,66 1 ,21 1 ,24 0,79 8,34 1 ,24 0,90 3,16 121 124 79...
Ngày tải lên: 18/06/2014, 16:20
Investigations on the antimalarial activity of alkoxylated and hydroxylated chalcones 2
... 55.50 28 .10 33.00 24 .85 100.00 Toxicity to macrophages (µM) c 30 30 30 10 10 30 30 10 10 ND 30 30 ND 10 30 30 10e Compound number 21 7 22 0 22 1 22 2 22 4 22 5 22 6 22 7 22 8 22 9 23 0 23 1 23 2 23 3d 23 4 23 5 23 6 ... 39 121 122 123 124 125 126 127 136 41f 20 1 20 2d 20 3 20 4 20 5d 20 6 20 7d 20 8d 20 9d 21 0d 21 1 24 5 21 2d 21 3d 21 4d 21 5d 21 6d Ring B 4’-ethoxy 4’-butoxy 2 ,4’dihydroxy 4’-hydroxy Ring A 4-fluoro 2, 4-dichloro ... 13.16 10.85 29 .31 29 .31 1.57 4.07 11.73 12. 63 IC50 (µM) b 38.0 32. 2 25 .4 25 .8 30.4 20 .4 21 .7 18.4 17.70 24 .50 29 .6 35.45 188.00 28 .00 12. 85 62. 50 61.50 25 .50 35.50 47.00 31.00 32. 50 29 .50 ND Toxicity...
Ngày tải lên: 17/09/2015, 17:18
Tài liệu The Influence of Human Activity on the Environment ppt
... stations produces carbon dioxide, sulphur dioxide and other greenhouse gases • carbon dioxide traps heat in the atmosphere and causes the temperature of the earth to rise • This leads to disruption ... growing population This causes several problems Burning the timber increases the level of carbon dioxide in the air Less trees means less carbon dioxide absorbed for photosynthesis Soil is eroded ... crops • They also kill harmless insects or can get washed into rivers and pollute the water • They may even end up in the food chain In the 1960s, DDT in the food chain threatened bird populations...
Ngày tải lên: 26/01/2014, 10:20
Tài liệu Báo cáo khóa học: The effect of mutations surrounding and within the active site on the catalytic activity of ricin A chain pptx
... Y80 Y 123 N 122 R258 R134 N 122 R258 R134 R213 R213 Fig Models of hexanucleotide binding in the active site of RTA (based upon [10]) The structures are shown as stereo images with the C1G2A3G4A5G6 ... vicinity of residue 122 The backbone and sidechains of the N 122 A substitution are shown as stereo images in thick ball and stick and the position of the Asn 122 side-chain of the wild-type enzyme ... respectively (Fig 2A) Substitution of Arg258 with Ala (R258A) had no effect on activity whereas substitution of Arg258 with Asp (R258D) lowered the activity niinefold (Fig 2B) Finally, substitution of Arg48...
Ngày tải lên: 19/02/2014, 12:20
Tài liệu Báo cáo khoa học: Coordination chemistry of iron(III)±porphyrin±antibody complexes In¯uence on the peroxidase activity of the axial coordination of an imidazole on the iron atom ppt
... face of the porphyrin and, in the more favorable conformation, H2O2 binds to the iron on the same face of the porphyrin as the catalytic COOH residue, the imidazole binding to the iron on the opposite ... of H2O2 on the iron of 13G10-(Fe(ToCPP), (B) binding of two CN± ligands on the iron of 13G10-(Fe(ToCPP), (C) binding of H2O2 and imidazole on the iron of 13G10-(Fe(ToCPP), (D) binding of H2O2 and ... to the iron(III) of Fe(ToCPP) and Fe(ToCPP))13G10 The second part of our results concerns the binding of imidazole derivatives on the iron of Fe(ToCPP) either alone in solution or inside the...
Ngày tải lên: 21/02/2014, 03:20
Tài liệu Learning 2.0 - The Impact of Social Media on Learning in Europe ppt
... Content 90 80 70 60 50 % 40 30 20 10 A 38 B C 28 D 30 E 28 F 18 G 24 H I J K L 11 M 20 61 15 45 49 46 29 38 11 12 10 19 33 74 84 23 26 64 73 69 78 65 74 45 51 59 67 22 24 24 28 10 12 14 28 32 ... http://ec.europa.eu/education/lifelong-learning-programme/doc/sec2 629 .pdf European Commission (20 09) Commission Working Document Consultation on the Future “EU2 020 ” Strategy COM (20 09)647 final, 24 /11 /20 09: http://ec.europa.eu/dgs/secretariat_general/eu2 020 /docs/com _20 09_647_en.pdf ... of new skills are considered by the Commission, in its 20 09 consultation document on the future "EU 20 20 strategy" (COM (20 09)647 final) amongst the key drivers for Europe's economic and social...
Ngày tải lên: 21/02/2014, 21:20
Báo cáo khoa học: The antibiotic activity of cationic linear amphipathic peptides: lessons from the action of leucine/lysine copolymers on bacteria of the class Mollicutes doc
... 6 .25 6 .25 6 .25 12. 5 R 100 12. 5 R R R R 12. 5 R 100 50 25 6 .25 6 .25 6 .25 12. 5 R 25 6 .25 100 50 R 50 0.39 R R R 50 12. 5 6 .25 6 .25 12. 5 R 25 6 .25 100 100 R 100 3. 12 R R 100 50 12. 5 6 .25 6 .25 12. 5 ... DnsLK9 (2. 0) DnsLK11 (2. 0) DnsLK15(W14) (2. 0) Melittin 100 100 50 25 3. 12 1.56 1.56 3. 12 50 25 0.78 3. 12 6 .25 12. 5 12. 5 0.78 R R 100 50 12. 5 3. 12 3. 12 6 .25 50 50 12. 5 12. 5 6 .25 25 25 6 .25 R R 100 25 ... for the design of highly cytotoxic alpha-helical amphipathic peptides In Peptides 1994 – Proceedings ´ 22 16 L Beven et al (Eur J Biochem 27 0) 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 of the...
Ngày tải lên: 23/03/2014, 17:21
Báo cáo khoa học: The enzymatic activity of SR protein kinases 1 and 1a is negatively affected by interaction with scaffold attachment factors B1 and 2 pot
... phosphorylation of the FEBS Journal 27 6 (20 09) 521 2– 522 7 ª 20 09 The Authors Journal compilation ª 20 09 FEBS 522 5 SRPK1/1a inhibition by interaction with SAFB1 /2 19 20 21 22 23 24 25 26 27 28 29 30 D ... Expression of the fusion proteins GST–SAFB1C, GST– SAFB1CDREand GST–SAFB2C was induced with mm FEBS Journal 27 6 (20 09) 521 2– 522 7 ª 20 09 The Authors Journal compilation ª 20 09 FEBS 522 3 SRPK1/1a ... and the eluate was probed with the FEBS Journal 27 6 (20 09) 521 2– 522 7 ª 20 09 The Authors Journal compilation ª 20 09 FEBS 521 9 D Tsianou et al In pu t( 20 % ) SRPK1/1a inhibition by interaction...
Ngày tải lên: 30/03/2014, 01:20
Báo cáo Y học: Barley a-amylase Met53 situated at the high-affinity subsite )2 belongs to a substrate binding motif in the bfia loop 2 of the catalytic (b/a)8-barrel and is critical for activity and substrate specificity pot
... H92AMY2, T94AMY2, A95AMY2, Y130AMY2, A145AMY2, F180AMY2, K182AMY2, W206AMY2, S208AMY2, Y211AMY2, H288AMY2, Q294AMY2, M296AMY2 and Q35TAA, H 122 TAA, R204TAA, K209TAA, H210TAA, G234TAA, D340TAA, ... from GH77 4763 46 62 6883 7489 7186 6883 50 72 90113 69 92 96119 111135 20 221 7 4866 7895 7895 8 128 30 25 528 5 84109 84101 6896 19 521 4 477494 20 021 7 19 621 3 5775 5573 6381 23 625 3 4160 25 728 6 118144 4867 ... Position Source Enzyme P00693 P04063 P27935 Q41770 P08117 P17859 P00690 P00691 P10 529 P21567 P19531 P 328 18 P266 12 P006 92 P0 627 8 P21543 P25718 P 229 63 P19571 Q 525 16 P30538 P38939 P38940 P29964 P28904...
Ngày tải lên: 31/03/2014, 08:20
Báo cáo khoa học: Swollenin, a Trichoderma reesei protein with sequence similarity to the plant expansins, exhibits disruption activity on cellulosic materials pptx
... to demonstrate the phenotype of the swo1 disruption, its effect either on the formation of the T reesei cell wall and growth of the fungal mycelium or on the degradation of cellulosic carbon sources ... Buffer Control yeast Swollenin-producing yeast M Urea 22 9 22 5 186 1 32 10.9 10.4 5.0 16 .2 Ó FEBS 20 02 A fungal expansin homologue (Eur J Biochem 26 9) 420 9 Fig Atomic force microscopy image of the ... concentration of lgÆmL)1 were used as controls for the swollenin [28 ,29 ] After incubation for h at 25 °C, the suspended fibers were filtered off and the amount of reducing sugars released into the...
Ngày tải lên: 31/03/2014, 09:20
SYNTHESIZE AND INVESTIGATE THE CATALYTIC ACTIVITY OF THREE-WAY CATALYSTS BASED ON MIXED METAL OXIDES FOR THE TREATMENT OF EXHAUST GASES FROM INTERNAL COMBUSTION ENGINE
... 1.4 Mechanism of the reactions 1.4.1 1.4 .2 1.4.3 1.4.4 1.5 Aims of the thesis 2. 2 20 21 23 23 24 25 26 27 28 37 37 Sol-gel synthesis of mixed catalysts Catalysts supported on γ-Al2O3 Aging process ... CO2 CO + H2O → CO2 + H2 Reduction: NO (or NO2) + CO → ½ N2 + CO2 NO (or NO2) + H2 → ½ N2 + H2O (2 + n /2) NO (or NO2) + CyHn → (1+n/4) N2 + yCO2 + n /2 H2O All the above reactions required some ... (22 0) (311) 43.3 62. 9 (400) (440) 38.5 52. 5 54.77 ( 122 ) (118) (133) 39 46.3 48.9 (20 0) (-1 12) ( -20 2) 36.5 47.6 57 .2 (101) (1 02) (110) 50.6 60 .2 (22 0) (311) 37.6 39.5 45.8 (311) (22 2) (400) 26 .2...
Ngày tải lên: 12/05/2014, 17:14
báo cáo hóa học: "The impact of regular physical activity on fatigue, depression and quality of life in persons with multiple sclerosis" pot
... Outcomes 20 09, 7:68 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 Stuifbergen AK, Blozis SA, Harrison TC, Becker HA: Exercise, functional limitations, and quality of life: a longitudinal ... depression and fatigue scores BDI Exercise Status Disease Severity Interaction effect SF36BP SFGH 5.6 32* 1.159 0. 822 12. 983** 39.953** 2. 527 * 1 .23 6 10.437** 0.988 2. 149 4. 921 ** 2. 754* 9. 325 ** 2. 810* ... Nonexercisers The MSIS -29 measures the impact of the disease on the individual of the previous weeks, it is possible that regular exercise may improve the MSIS -29 by improving either the perception or the...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học: " The effect of hip abduction on the EMG activity of vastus medialis obliquus, vastus lateralis longus and vastus lateralis obliquus in healthy subjects" pot
... diminished EMG activity of the VMO in relation to that of the VL [7-9], and the delayed onset of VMO activation in relation to the VL [10 12] caused by the inhibition of pain, effusion and atrophies[13] ... 24 :160-5 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 Cowan SM, Bennell KL, Hodges PW, et al.: Delayed onset of electromyographic activity of vastus medialis obliquus ... flexion compared with the higher activity of the VLL at 15° of flexion, demonstrating that the VMO and VLO muscle have the same behavior suggesting a synchronic antagonist stability role of the...
Ngày tải lên: 19/06/2014, 10:20
Báo cáo hóa học: " Epitope characterization of the protective monoclonal antibody VN04-2 shows broadly neutralizing activity against highly pathogenic H5N1" ppt
... Coast/1787/06 A/Zhe Jiang/16/06 A/DK/Guangzhou /20 /05 A/Indonesia/CDC597/06 A/Indonesia/5/05 A/CK/Indonesia/R60/05 1 2. 2 2. 2 2. 3.4 2. 1 .2 2.1.3 2. 1.1 124 129 136 137 138 140 141 154 155 156 189 D N ... determine the actual effects mutations in this region of the HA gene has on antibody binding and the utility of the antibody for protection against recently circulating H5N1 viruses The mAb VN04 -2 was ... various HA-foldons using Biacore SPR analysis The antibody showed a range of association constants for the HAs with the highest calculated against A/Vietnam/ 120 3/04 (2. 63 × 108 M-1) and the lowest...
Ngày tải lên: 20/06/2014, 01:20
báo cáo hóa học:" The impact of regular physical activity on fatigue, depression and quality of life in persons with multiple sclerosis" pdf
... Outcomes 20 09, 7:68 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 Stuifbergen AK, Blozis SA, Harrison TC, Becker HA: Exercise, functional limitations, and quality of life: a longitudinal ... depression and fatigue scores BDI Exercise Status Disease Severity Interaction effect SF36BP SFGH 5.6 32* 1.159 0. 822 12. 983** 39.953** 2. 527 * 1 .23 6 10.437** 0.988 2. 149 4. 921 ** 2. 754* 9. 325 ** 2. 810* ... Nonexercisers The MSIS -29 measures the impact of the disease on the individual of the previous weeks, it is possible that regular exercise may improve the MSIS -29 by improving either the perception or the...
Ngày tải lên: 20/06/2014, 16:20
Báo cáo hóa học: "Biocompatible micro-sized cell culture chamber for the detection of nanoparticle-induced IL8 promoter activity on a small cell population" pot
... used The induction of the promoter is linked to the production of the inflammatory cytokine, and consequently, the intensity of the IL8 promoter activation is proportional to the GFP expression, ... Opt 20 10, 15: 027 007 14 De Angelis F, Das G, Candeloro P, Patrini M, Galli M, Bek A, Lazzarino M, Maksymov I, Liberale C, Andreani LC, Di Fabrizio E: Nanoscale chemical 20 21 22 23 24 25 26 27 28 ... in their fabrication, and wrote the main parts of the manuscript GO carried out the transfection of the reporter cell line and was involved in the preparation of the manuscript AS fabricated the...
Ngày tải lên: 21/06/2014, 00:20
Báo cáo hóa học: " A Receiver for Differential Space-Time π/2-Shifted BPSK Modulation Based on Scalar-MSDD and the EM Algorithm" ppt
... Inform Theory, vol 49, no 6, pp 1400–1416, 20 03 [23 ] D M Ionescu, On space-time code design,” IEEE Transactions on Wireless Communications, vol 2, no 1, pp 20 28 , 20 03 [24 ] T K Moon, The expectation-maximization ... Clearly, the performance of the first iteration is substantially inferior to that of the conventional ST-DD initialization In this case, the observation window for the conventional detector is only ... estimation (21 ) and MRC detection (22 ) units in the iterative section of the receiver Secondly, as the Mackenthun algorithm can only be applied to static channels, the scalar-MSDD component would...
Ngày tải lên: 23/06/2014, 00:20
The Intelligent Investor: The Definitive Book On Value part 2 ppt
... in 1949 the figures were almost the exact opposite: the bonds returned only 2. 66% and the stocks yielded 6. 82% .2 In previous editions we have consistently urged that at least 25 % of the conservative ... representative common stocks At the beginning of 19 72 the return was 7.19% on highest-grade bonds versus only 2. 76% on industrial stocks (This compares with 4.40% and 2. 92% respectively at the end of ... application of these principles must be adapted to significant changes in the financial mechanisms and climate The last statement was put to the test during the writing of the present edition, the...
Ngày tải lên: 04/07/2014, 15:20