2—floor and footing design

... leakage, and various other design recommendations intended to ensure serviceability of water tanks and other liquid-containing structures are given in Sections 2.2 to 2.4 2 .2—Floor and footing design ... evaluate unusual design requirements 2.4—Roof design 2.4.1 Flat concrete roofs—Flat concrete roofs and their supporting columns and footings should be designed in accordance with ACI 318-99 and should ... herein reflect over five decades of experience in designing and constructing circular prestressed structures When designed and built with understanding and care, these structures can be expected to...

Ngày tải lên: 24/10/2014, 17:26

... relatively prime, each PA,λ(t) for λ = is a constant, and thus QA (t) is a periodic function with average value 0, and this property determines QA (t), and thus PA (t) Discussions of QA (t) can be found, ... Since B2i+1 = for i > 0, (−1)j−1 Bj = −Bj for j > 1, and (3) follows from (5) and (6) Remark It is possible to avoid the use of complex analysis and give a purely formal power series proof of the ... Bernoulli numbers Bj by z = ez − Bj j≥0 zj j! (1) (so B0 = 1, B1 = − , B2 = , B4 = − 30 , and Bn = if n is odd and greater than 1.) Theorem PA (t) = a1 · · · an = a1 · · · an n−1 (−1)m (n − − m)!...

Ngày tải lên: 07/08/2014, 06:22

... composed of parallel b strands associated to an antiparallel strand (b2) and is surrounded by helices (a1, a2, a3, a7 and a8) The second domain consists of helices a4, a5 and a6 all clustered on ... 205 and 215 nm, indicating that Rv1399c is composed of 22% of a-helices, 25% of b-strand and 39% of random coil The catalytic triad is located at the bottom of a small ˚ ˚ pocket, 20 A length and ... proton carrier and Asp260 is the charge relay network Ser162 is located within the Ônucleophilic elbowÕ connecting strand b5 and helix a3, while His290 and Asp260 emerge from the b8-a8 and b7-a7 loops,...

Ngày tải lên: 07/03/2014, 16:20

... early and late flushing trees (P > 0.0001) which accounted for almost 20% of all variation Means and standard errors for vessel areas for early and late flushing trees were 67 134 ± 090 μm and ... individual μ is the overall vessel area; g is the effect of genoi as random; ij e is the normally and independently distributed random deviation of genotype i, with a mean of zero Differences between ... Q robur planted in an unreplicated design Investigations into the association between the progress of flushing and vessel size were undertaken on 20 early and 20 late flushing trees to indigenous...

Ngày tải lên: 08/08/2014, 19:21

... implementation and sustainability issues [28] Figure provides a visual representation and framework for understanding the system redesign associated with successfully tailoring the intervention and the ... componentunderstanding the transformation (system redesign) associated with successful SMA Visual representation and framework for Visual representation and framework for understanding the transformation ... structure redesign, a necessary step to sustain the innovation This system redesign needed to happen and could not have occurred devoid of appreciating and co-adapting the context and the intervention...

Ngày tải lên: 11/08/2014, 05:21

... implementation and sustainability issues [28] Figure provides a visual representation and framework for understanding the system redesign associated with successfully tailoring the intervention and the ... componentunderstanding the transformation (system redesign) associated with successful SMA Visual representation and framework for Visual representation and framework for understanding the transformation ... structure redesign, a necessary step to sustain the innovation This system redesign needed to happen and could not have occurred devoid of appreciating and co-adapting the context and the intervention...

Ngày tải lên: 11/08/2014, 16:21

... thaliana FOX lines and HN and KS screened the mutants and identified inserted cDNA by supervision of YKo, TI, and MM YKa designed this study, produced the AtYLMG1-1 overexpressing and knockdown lines, ... wild type, FOX lines and the 35S-AtYLMG1-1 transgenic plants Transcript levels were analyzed by RT-PCR in the wild type (lane and 5), FN026 (lane and 6), FN028 (lane and 7), and the 35S-AtYLMG1-1 ... AS#1, and AS#2 UBQ1 was used as the quantitative control (D) Chloroplasts in leaf mesophyll cells of the wild type and the AtYLMG1-1 knockdown line Chloroplasts in expanding leaf cells and the...

Ngày tải lên: 12/08/2014, 03:21

... Checklist for Design 50 Budgets and Expenditures 50 For Further Information 51 Trial Design 55 Baseline Measurements 56 Controlled Randomized Clinical Trials 57 Randomized Trials 58 Blocked Randomization ... A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS A MANAGER’S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS Second Edition Phillip I Good, ... to the Design and Conduct of Clinical Trials, by Phillip I Good Copyright ©2006 John Wiley & Sons, Inc CHAPTER CUT COSTS AND INCREASE PROFITS had to carve out each letter by hand and cost their...

Ngày tải lên: 14/08/2014, 07:20

... the design and conduct of clinical trials PLAN A Predesign Phase Form your design team (see Chapter 4) Your team’s first step should be to decide whether the study is actually worth performing and ... nature and duration of the study, virtually all members of the design and implementation teams may be called upon In Chapter 14 we discuss the need to assemble external review panels and their ... Integrity and security of data To say nothing of investigators, investigational laboratories, safety and efficacy review committees, and patients 13 Don’t attribute this quote to me, Professor Deming and...

Ngày tải lên: 14/08/2014, 07:20

... the Design and Conduct of Clinical Trials, by Phillip I Good Copyright ©2006 John Wiley & Sons, Inc CHAPTER TRIAL DESIGN 55 the measurements, and the criteria for interpretation—as uniform and ... in Clinical Trials: Methods and Practice Oxford University Press Goldman DP et al (2000) The Cost of Cancer Treatment Study’s Design and Methods Santa Monica, CA: Rand Green S; Benedetti J; Crowley ... management and a lack of clarity of the protocol and/ or case report forms were the primary offenders They pointed out that training and supervision of data managers, precision in writing protocols, standardization...

Ngày tải lên: 14/08/2014, 07:20

... understood and thoroughly documented; see for example, Yao and Wei (1996) and Li, Shih, and Wang (2005) The chief drawback until recently was the lack of commercially available software with which to design ... or electronic submissions, for the format and organization of reports, for the format and contents of tables, and for the format and naming of files and directories The CTD provides for analysis ... and will • • • • • administer and obtain informed consent from all patients; administer the intervention and record and report measurements only as specified in the protocol; submit all data and...

Ngày tải lên: 14/08/2014, 07:20

... African-American, 14 Hispanic, and 24 subjects designating themselves as Asian or other A total of 856 potential subjects were interviewed Sites 2, 4, and have recruited 100%, 95%, and 80% of their expectations ... your final report and an electronic copy of your database and the programs you’re used to retrieve and analyze the data In the United States, the latter is termed an e-sub or CANDA (Computer-Aided ... process for weeks CANDAs eliminate much of this delay By employing computer-assisted data entry you are automatically in a position to submit a CANDA Between 1991 and 1994, CANDAs in the United...

Ngày tải lên: 14/08/2014, 07:20

... needs to sit down with the principal investigator and coordinator at each site to ensure a mutual understanding of recruitment guidelines and patient handling After such discussions, each site coordinator ... software and the options available to you Transfer of data from data entry to data storage and from data storage to your report generating and statistical analysis software Maintaining the security and ... elimination of missing data and the need for extensive time-consuming follow-up Figure 10.1d illustrates the use of graphics and layout options to create a user-friendly design for the data entry...

Ngày tải lên: 14/08/2014, 07:20

... data collection and verification is conducted via the Web, new data management methods and software may be required See, for example, Brandt et al (2000) and Wübbelt, Fernandez, and Heymer (2000) ... project manager and production and supplies on hand continually matched to forecast needs LATE AND INCOMPLETE FORMS Late and incomplete forms are the major source of cost overruns and trial delays ... are on serve both to maintain hand morale and to forestall Procedure manuals are on problems with patients, the hand investigator, and the Instructions, containers, and investigator’s staff labels...

Ngày tải lên: 14/08/2014, 07:20

... unbalanced design in which a greater proportion of individuals are randomized to the more favorable treatment See, for example, Armitage (1985), Lachin et al (1988), Wei et al (1990), and Ivanaova and ... comparison of urn designs for randomized clinical trials of K > treatments J Biopharm Stat 10:93–107 Lachin JM; Matts JP; Wei LJ (1988) Randomization in clinical trials: conclusions and recommendations ... by the Sandoz drug company and reproduced with permission from the StatXact manual Obviously, the results of sites 20 and 21 are the same, but are they the same as at the other sites? And what...

Ngày tải lên: 14/08/2014, 07:20

... of a mean and standard error as in 56 ± 3.2 is a long-standing tradition Indeed, many members of regulatory committees would protest were you to otherwise Still, mathematical rigor and not tradition ... computes the mean and standard error of the logarithms and determines a symmetric confidence interval One then takes the antilogarithms of the boundaries of the confidence interval and uses these ... software development and implementation, manual preparation and quality, training, data management, data integrity, data access, and data security, as well as monitoring costs, methods, and effectiveness...

Ngày tải lên: 14/08/2014, 07:20

... projected, and actual patient enrollment and study timelines, develop detailed visit schedule specification and tracking, including the identification of missing and late (CRFs), manage and track ... task of designing, managing, and analyzing clinical trials Some programs offer to it all, whereas others, more specialized, provide for speech recognition and collecting information from handheld ... blind breaks, and track patient availability and withdrawal information On the downside, Oracle Clinical is less flexible than Oracle, and we’ve found it easier to create reports and CRF’s in the...

Ngày tải lên: 14/08/2014, 07:20

... insightful look into English MAKE and DO collocations And, on account of this, well-formed utterances containing DO and MAKE collocations might be produced And, this constitutes the practical ... (1999), Sampling of populations: Methods and applications (3rd ed.), John Wiley and Sons, New York Marton, D M (1977), Research methods in education and psychology: Integrating diversity with ... research area of the thesis and provides theoretical background to the concerning matters In chapter 2, the methodology of the thesis including research-governing principles and research methods are...

Ngày tải lên: 10/08/2015, 19:47

... one another and share their experiences, conceptions and beliefs” Culture is a shared, learned, symbolic system of values, beliefs and attitudes that shapes and influences perception and behavior ... culture, language and speaking skills * Chapter provides an analysis on the attitudes of the teachers and students at -3- NTT towards the position of culture and speaking skills in ELT and towards ... embodies, and symbolizes cultural reality and in return cultural knowledge makes language alive Therefore, they co-exist and support each other The idea of the world is captured by culture And language...

Ngày tải lên: 07/09/2013, 13:00

... pay the bills, feed us and put my brother and I need to take responsibility for the kind of life we through school Both mum and dad knew the land create for ourselves well and had developed a strong ... illustrating this book and to my dad and brother for all their help too Thanks to my environmental law lecturers as well as Ben Rose and Al Gore for waking me up to the climate crisis and calling me ... passion and commitment to whatever they can to combat global warming Without their concern and stand, this book would not have been possible They have inspired me to be responsible for my actions and...

Ngày tải lên: 17/12/2013, 02:15