2 use of umbilical cord blood transfusion in patients with diabetes

Báo cáo y học: " The use of partial exchange blood transfusion and anaesthesia in the management of sickle cell disease in a perioperative setting: two case reports" pot

Báo cáo y học: " The use of partial exchange blood transfusion and anaesthesia in the management of sickle cell disease in a perioperative setting: two case reports" pot

... monitoring his vital signs and maintaining them within tight ranges Anaesthesia from the beginning up to the end of surgery lasted 80 minutes Postoperative care, including fluid management and weaning ... 0.18 Transfusion of units of red blood cells 5.3 0.25 Debridement humerus, transfusion of unit of red blood cell 4.4 0.21 General anaesthesia to insertion of central venous line 3.9 0.18 Transfusion ... 0.18 Transfusion of unit of red blood cell 5.2 0.24 Sequestrectomy tibia, transfusion of units of red blood cells Debridement tibia, transfusion of units of red blood cells In addition to classical...

Ngày tải lên: 11/08/2014, 12:20

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báo cáo khoa học: "Effect of anti-CD52 antibody alemtuzumab on ex-vivo culture of umbilical cord blood stem cells" doc

báo cáo khoa học: "Effect of anti-CD52 antibody alemtuzumab on ex-vivo culture of umbilical cord blood stem cells" doc

... trials now incorporate the expansion of http://www.jhoonline.org/content/1/1/19 one unit of cord blood following the infusion of another unexpanded unit in a double cord blood transplant setting The ... significant increase in CBT for patients in need of transplantation with matched unrelated allogeneic HSC This, coupled with the immediate availability of cord blood units (CBU), has made cord blood ... risks of expansion Moreover, a recent study from Shah et al shows that alemtuzumab is effective in decreasing the incidence of GVHD without increasing the risk of relapse in pediatric patients...

Ngày tải lên: 10/08/2014, 22:20

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báo cáo hóa học:" Phase I/II open-label study of the biologic effects of the interleukin-2 immunocytokine EMD 273063 (hu14.18-IL2) in patients with metastatic malignant melanoma" docx

báo cáo hóa học:" Phase I/II open-label study of the biologic effects of the interleukin-2 immunocytokine EMD 273063 (hu14.18-IL2) in patients with metastatic malignant melanoma" docx

... approaches for introducing IL2 into the tumor environment include injection of the cytokine intratumorally [17] and administering intratumoral injections of adenovirus encoding IL2 [18] In the later ... examined (Table 4) The IHC images from case 4104 are depicted in Figure 2D as a representative example of the post-dosing decrease in GD2 staining, and increase in S100 staining intensity and in ... with an inherently low probability (0.60) of observing even a single clinical response with patients and an underlying response rate of 15% To gain insight on the effects of the immunocytokine on...

Ngày tải lên: 18/06/2014, 15:20

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Báo cáo y học: "Filter survival time and requirement of blood products in patients with severe sepsis receiving drotrecogin alfa (activated) and requiring renal replacement therapy" pptx

Báo cáo y học: "Filter survival time and requirement of blood products in patients with severe sepsis receiving drotrecogin alfa (activated) and requiring renal replacement therapy" pptx

... difference in the minimum value of haemoglobin during DrotAA and in the post-DrotAA period (Table 4) A larger proportion of patients required platelet transfusion during DrotAA infusion compared with ... use of packed red cell (PRC) and blood products in patients with acute kidney injury requiring RRT treated with DrotAA A further comparison of the outcome parameters was made during the DrotAA infusion ... analysis in a small number of patients; however, this is an area of practice that is clinically important and in which it is difficult for individual clinicians working in smaller centres to gain sufficient...

Ngày tải lên: 13/08/2014, 11:23

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Báo cáo y học: "Red blood cell transfusion in patients with subarachnoid hemorrhage: a multidisciplinary North American survey" doc

Báo cáo y học: "Red blood cell transfusion in patients with subarachnoid hemorrhage: a multidisciplinary North American survey" doc

... together with interdisciplinary and international differences in transfusion preferences, should be taken into consideration in the planning of future studies This will help maximize clinician buy -in ... ongoing National Institutes of Health-sponsored phase II clinical trial in traumatic brain injury patients uses a PbtO2 threshold of 20 mmHg to initiate therapy [26] The clinical significance of ... monitoring in SAH patients report targeting higher Hb concentrations, especially in patients with DCI (mean Hb with multimodal monitoring, 8.82 g/dL (95% CI, 8.55 to 0.10); mean Hb without monitoring,...

Ngày tải lên: 14/08/2014, 07:21

11 336 0
báo cáo hóa học:" Short term effects of milrinone on biomarkers of necrosis, apoptosis, and inflammation in patients with severe heart failure" pot

báo cáo hóa học:" Short term effects of milrinone on biomarkers of necrosis, apoptosis, and inflammation in patients with severe heart failure" pot

... setting of more routine decompensated heart failure, and the effect milrinone in ischemic subset of patients deserves further investigation Conclusion Initiation of milrinone therapy in patients ... studies examining natriuretic peptide levels and/or inflammatory markers during inotrope administration with inconsistent results [8-11] Adding complexity to this picture is data indicating that ... regarding the effect of milrinone on apoptosis markers, or whether high-sensitivity troponin may reveal sub-clinical cardiac injury due to inotrope initiation We sought to determine the effect of initiating...

Ngày tải lên: 18/06/2014, 15:20

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báo cáo hóa học: " Is global quality of life reduced before fracture in patients with low-energy wrist or hip fracture? A comparison with matched controls" docx

báo cáo hóa học: " Is global quality of life reduced before fracture in patients with low-energy wrist or hip fracture? A comparison with matched controls" docx

... quality of life even before the fracture occur [29-32] The wrist patients have a modest decrease in health-focused quality of life within physical domain and scores in accordance with controls within ... analyses The values of the regression coefficients were interpreted according to Cohen's effect size index, in which coefficients in the range 0.2–0.5 are defined as indicating a small difference, ... or both of the total hip or lumbar spine L2–L4 was found in 33% of the wrist fracture patients, 59% of the hip fracture patients, and 16% of the controls The difference in frequency of osteoporosis...

Ngày tải lên: 18/06/2014, 19:20

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Báo cáo y học: "Alterations in Arterial Blood Parameters in Patients with Liver Cirrhosis and Ascite" docx

Báo cáo y học: "Alterations in Arterial Blood Parameters in Patients with Liver Cirrhosis and Ascite" docx

... cause of hypoxemia in alcoholic patients [19] Moreover, in these series of patients none presented with dyspnea or clinical signs of hepatopulmonary syndrome These findings confirm previous clinical ... diagnosed occurring in chronic liver disease of all types and mainly in severe suffering patients [4, 9, 10, 11] Liver cirrhosis is often accompanied by arterial hypoxemia in the absence of cardiopulmonary ... arguing whether or not hypoxemia develops in patients with intrapulmonary vasodilatation [15, 16] In our study all of patients with cirrhosis (Child-Pugh B and C) had hypoxemia Contradictory, according...

Ngày tải lên: 08/08/2014, 18:20

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Báo cáo y học: "The expansion of CD4+CD28– T cells in patients with rheumatoid arthritis" potx

Báo cáo y học: "The expansion of CD4+CD28– T cells in patients with rheumatoid arthritis" potx

... number of CD4+CD28– T cells in each of these disease categories is shown in Table The frequency of CD4+CD28– T cells was 4.82% in patients with limited joint manifestations, 7.05% in those with ... joint involvement The lowest frequency of CD4+CD28– T cells was in RA patients with limited joint manifestations Significantly higher numbers of CD28– lymphocytes were present in patients with ... thrombosis Clonal expansion of CD4+CD28– T cells has been found in the inflamed plaque of such patients [12] Table Frequency of CD4+CD28– T cells in control group and in patients with RA Subjects CD4+CD28–...

Ngày tải lên: 09/08/2014, 01:22

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Báo cáo y học: "Effect of adalimumab on neutrophil function in patients with rheumatoid arthritis" pps

Báo cáo y học: "Effect of adalimumab on neutrophil function in patients with rheumatoid arthritis" pps

... targets of anti-TNF-α activity in RA, and may provide an insight into a new and interesting mechanism of action of anti-TNF-α mAbs in the control of inflammatory arthritis Competing interests ... N-formyl-1methionyl-l-leucyl-1-phenylalanine: analysis of single cell movement J Leukocyte Biol 1992, 52:630-636 Binder R, Kress A, Kan G, Herrmann K, Kirschfink M: Neutrophil priming by cytokines and vitamin D binding protein (Gc-globulin): ... initiation of treatment with leflunomide or methotrexate in patients with rheumatoid arthritis: findings in a prospective, randomized, double-blind clinical trial in fifteen patients Arthritis Rheum...

Ngày tải lên: 09/08/2014, 06:22

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Báo cáo khoa học: "Prognostic significance of IDH-1 and MGMT in patients with glioblastoma: One step forward, and one step back" pot

Báo cáo khoa học: "Prognostic significance of IDH-1 and MGMT in patients with glioblastoma: One step forward, and one step back" pot

... chemotherapy with TMZ at a dose of 50 mg/m2 without adjuvant TMZ was performed in our institution, therefore 124 patients had been treated according to this regimen, and 36 patients received TMZ according ... both endpoints were comparable in patients with active MGMT or with MGMT silencing The only subgroup of patients showing a significant impact of MGMTpromoter methylation on survival were patients ... mg in only 22%) as well as in the maintenance phase (no adjuvant treatment in 79 % and a mean of cycles in 21% of patients) However, inspite of this difference, outcome between the two dosing...

Ngày tải lên: 09/08/2014, 09:21

18 365 0
Báo cáo y học: "Increased serum levels of macrophage migration inhibitory factor in patients with primary Sjögren''''s syndrome" potx

Báo cáo y học: "Increased serum levels of macrophage migration inhibitory factor in patients with primary Sjögren''''s syndrome" potx

... other laboratory findings listed in Table None of the patients with pSS had an increased level of CRP There was a tendency for increased numbers of IL-10-secreting PBMC in patients with pSS (p < ... al We examined serum levels of MIF in patients with pSS and the relation of these levels to clinical and laboratory findings In addition, we analysed associations of MIF concentrations with various ... elevated in our cohort, the increased MIF levels in patients with pSS cannot be explained by differences in the extent of acutephase response Hence, specific mechanisms of MIF induction in pSS remain...

Ngày tải lên: 09/08/2014, 10:20

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Báo cáo khoa học: " Quality of life and salivary output in patients with head-and-neck cancer five years after radiotherapy" pptx

Báo cáo khoa học: " Quality of life and salivary output in patients with head-and-neck cancer five years after radiotherapy" pptx

... combined with parotid salivary output of patients with head-and-neck malignancies treated with RT We found a deterioration of most of the QOL items after completion of radiotherapy compared with ... RT with curative intent were included in the study Other inclusion criteria were no previous RT or surgery of the parotid glands, no history of suffering from malignancies or other diseases of ... http://www.ro-journal.com/content/2/1/3 Table 2: Mean scores of the scales and single items of questionnaire for patients with cancer of the head- and-neck treated with radiotherapy with or without surgery A significant outcome...

Ngày tải lên: 09/08/2014, 10:21

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Báo cáo y học: "Decreased levels of the gelsolin plasma isoform in patients with rheumatoid arthritis" docx

Báo cáo y học: "Decreased levels of the gelsolin plasma isoform in patients with rheumatoid arthritis" docx

... with MTX, in combination with leflunomide, in combination with azathioprine, and with sulfasalazine), and azathioprine (2 patients) Nine patients received a combination of DMARD (8 patients received ... Vitamin D binding protein (Gc-globulin) Endocr Rev 1989, 10:294-307 18 Lind SE, Smith DB, Janmey PA, Stossel TP: Role of plasma gelsolin and the vitamin D-binding protein in clearing actin from ... model of plasma gelsolin (pGSN) function in clearing actin from synovial joints of rheumatoid arthritis patients with acute joint effusion (1) (pGSN) function in clearing actin from synovial joints...

Ngày tải lên: 09/08/2014, 13:22

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Báo cáo y học: " Effects of cyclophosphamide on pulmonary function in patients with scleroderma and interstitial lung disease: a systematic review and meta-analysis of randomized controlled trials and observational prospective cohort studies" ppt

Báo cáo y học: " Effects of cyclophosphamide on pulmonary function in patients with scleroderma and interstitial lung disease: a systematic review and meta-analysis of randomized controlled trials and observational prospective cohort studies" ppt

... scleroderma and in 40% of patients with diffuse SSc [5] High-resolution computed tomography detects ILD changes in 90% to 100% of SSc patients [2,5] ILD is associated with increased mortality in patients ... data, CYC treatment in patients with SScrelated ILD does not appear to result in clinically significant improvement of pulmonary function Since none of the patients included in these studies were ... the drug in patients with SSc [28,29] The adverse events counted in our nine studies included two cases of hemorrhagic cystitis [17] and several cases of hematuria – one case in Valentini and...

Ngày tải lên: 09/08/2014, 13:22

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Báo cáo y học: "High frequency of corticosteroid and immunosuppressive therapy in patients with systemic sclerosis despite limited evidence for efficacy" doc

Báo cáo y học: "High frequency of corticosteroid and immunosuppressive therapy in patients with systemic sclerosis despite limited evidence for efficacy" doc

... of the clinical centers specializing in the care of SSc patients participating in the network, but also of patients who are seen only once a year in a clinical center participating in the network ... College of Rheumatology criteria or the main symptoms of SSc, combined with another nonorgan-specific autoimmune disease or with the main symptoms of such a disease and, as a rule, with proof of characteristic ... College of Rheumatology, with the exception of higher rates of D-penicillamine use in SSc in North America (that is, 20% for skin involvement) Conclusion The present study is the first investigating...

Ngày tải lên: 09/08/2014, 13:22

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Báo cáo y học: " Management of HIV-1 associated hepatitis in patients with acquired immunodeficiency syndrome: role of a successful control of viral replication" ppsx

Báo cáo y học: " Management of HIV-1 associated hepatitis in patients with acquired immunodeficiency syndrome: role of a successful control of viral replication" ppsx

... improvement of antiretroviral drug tolerability only in coinfected patients In conclusion, in HIV-1 infected patients presenting with an acute onset of abnormal LFTs, after the exclusion of the most ... performed for the onset of disseminated Kaposi’s sarcoma (KS) lesions with visceral involvement (CDC C3) HAART with indinavir, lamivudine and stavudine was started, shortly allowing an immune-virological ... he continued HAART, switching from indinavir to nevirapine for simplification, and from stavudine to tenofovir for the onset of peripheral neuropathy During this period plasma HIV RNA remained...

Ngày tải lên: 10/08/2014, 05:22

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Báo cáo y học: "The reliability of toe systolic pressure and the toe brachial index in patients with diabetes" ppsx

Báo cáo y học: "The reliability of toe systolic pressure and the toe brachial index in patients with diabetes" ppsx

... explored reliability of the measurement of Toe Systolic Pressures in patients with diabetes and varying stages of PAOD with intra-class correlations (ICCs) ranging from 0.77 to 0.99 in intrarater reliability ... pressure in the clinical setting [33] The role of the observer in recording the systolic pressure is eliminated and replaced with a digital device programmed to take readings at specific intervals In ... [34-36] The aim of this study was to determine both the intra and inter-rater reliability of the measurement of toe systolic pressure and the Toe Brachial Index in patients with diabetes using a manual...

Ngày tải lên: 10/08/2014, 21:24

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Báo cáo y học: "Activation of monocytes and cytokine production in patients with peripheral atherosclerosis obliterans" docx

Báo cáo y học: "Activation of monocytes and cytokine production in patients with peripheral atherosclerosis obliterans" docx

... who demonstrated an increase in serum levels of these cytokines in patients with intermittent claudication The authors suggested that a high level of cytokines is indicative of some complications ... placed in tubes containing heparin for biochemical analysis, cytokine measurement and the isolation and culturing of monocytes Isolation of peripheral blood mononuclear cells Heparinized venous blood ... alanine aminotransferase (ALT), aspartate aminotransferase (AST), urea and creatinine of patients and control subjects are shown in Table Patients and control subjects presented levels within...

Ngày tải lên: 11/08/2014, 03:20

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Báo cáo y học: " Effects of asenapine on depressive symptoms in patients with bipolar I disorder experiencing acute manic or mixed " pot

Báo cáo y học: " Effects of asenapine on depressive symptoms in patients with bipolar I disorder experiencing acute manic or mixed " pot

... reported in patients with bipolar I or II depression receiving quetiapine or in patients with bipolar I depression receiving olanzapine/ fluoxetine [21-23] They are also within the range of values ... olanzapine alone (versus 1.4-3.6 points for olanzapine alone in the studies included in this analysis) and 5.9-7.8 points when combined with fluoxetine [21] In the current analysis, olanzapine also ... were in line with those reported from the observed case analysis The efficacy of asenapine in treating depressive symptoms is supported by in vitro and in vivo preclinical findings Asenapine has...

Ngày tải lên: 11/08/2014, 15:22

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