2 patients treated for relapse with high dose chemotherapy and stem cell transplantation
Báo cáo khoa học: "Combined low initial DNA damage and high radiation-induced apoptosis confers clinical resistance to long-term toxicity in breast cancer patients treated with high-dose radiotherapy" pdf
Ngày tải lên :
09/08/2014, 09:20
... patients with LABC were treated with radical mastectomy [1,2]; thereafter, systemic therapy was subsequently incorporated along with surgery and radiotherapy (RT) [3] However, even with such ... after higher doses, and in humans, it is even >5 years for moderate doses or for very late reacting tissues Late damage progresses over time, and it is important to highlight that doses believed safe ... prescribed at a dose of 9.4-21.6 Gy [17] Peripheral nodes were treated by conventional fractionation (1.8/2Gy/day) at doses of 50-70 Gy Supraclavicular and axillary lymph node areas were treated with an...
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Báo cáo khoa học: "Constitutive gene expression profile segregates toxicity in locally advanced breast cancer patients treated with high-dose hyperfractionated radical radiotherapy" pot
Ngày tải lên :
09/08/2014, 09:22
... outcomes with an acceptable toxicity have been obtained by using high total doses radiation administered in two small fractions per day compared with standard RT protocols [4] Some patients treated with ... from un-irradiated and irradiated lymphocytes and the development of toxicity due to RT in patients with LABC Patients and methods Twelve consecutive patients treated between 1991 and 1997 by a hyperfractionated ... Array scanning, image analysis and data normalization were performed as Figure Experimental design Experimental design RNA from lymphocytes treated with and Gy dose of radiation were compared...
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Báo cáo hóa học: " Three agonist antibodies in combination with high-dose IL-2 eradicate orthotopic kidney cancer in mice" pptx
Ngày tải lên :
18/06/2014, 16:20
... IL-2, we treated tumor-bearing mice with Tri-mAb in combination with low dose (10,000 IU) or medium dose (50,000 IU) or high dose (100,000 IU) IL-2 daily for days and monitored survival Westwood ... incubated for 18 hours at 37°C in 5% CO2, and GolgiStop (BD Biosciences, San Jose, CA) was added for the last 12 hours Cells were harvested the next day and stained and assessed by flow cytometry for ... established orthotopic and metastatic renal cell carcinoma without nephrectomy and ascertain if treatment could be optimized using cytokine support Materials and methods Cell lines and mice Renca is...
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báo cáo khoa học: " Better retention of Malaysian opiate dependents treated with high dose methadone in methadone maintenance therapy" potx
Ngày tải lên :
11/08/2014, 18:20
... sufficient for our Malaysian patients, our results showed otherwise Our findings were also in parallel with studies that showed a sufficiently high dose was required for improved outcomes [37] High doses ... low a dose will lead to relapse and failure whereas too high a dose will lead to toxicity such as prolongation of QT interval and subsequent fatal polymorphic ventricular fibrillation [20] For ... were divided into groups according to the daily dose level that they received, “low dose (0-39 mg), “intermediate dose (40-79 mg) and high dose (80 mg or more) [19] Summary statistics were...
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COOPERATIVE STEWARDSHIP: Managing the Nation’s Multidisciplinary User Facilities for Research with Synchrotron Radiation, Neutrons, and High Magnetic Fields ppt
Ngày tải lên :
06/03/2014, 15:20
... plasma confinement for new energy sources; magnetic levitation for high- and low-speed transportation; large motors for industrial use and ship propulsion; medical diagnostic systems (magnetic resonance ... characterization systems; materials growth and processing; and magnetic separation Research with high magnetic fields has led to the development of magnetic resonance imaging for medical purposes and of ... particle accelerators and neutron reactors were built for a single purpose (e.g., high- energy or nuclear physics research), and they were managed by a single agency and operated by and for a single scientific...
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Báo cáo y học: "Primary treatment of acromegaly with high-dose lanreotide: a case series" ppt
Ngày tải lên :
11/08/2014, 12:20
... assessed at different time-points within the range **Before treatment with lanreotide but after treatment with octreotide for approximately 13 and 27 months for the GH and IGF-1 values, respectively ... This high dose of lanreotide has now been given to one patient for approximately six months and to another for approximately three months with no unexpected adverse events The use of such high doses ... time of diagnosis, and his GH levels were 8.48 ng/ml and not suppressed by a standard oral glucose load Our patient was initially treated with 10 mg of octreotide every four weeks for 27 months During...
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Báo cáo y học: " Impact of prolonged treatment with high-dose ciprofloxacin on human gut flora: a case report" potx
Ngày tải lên :
11/08/2014, 12:20
... uniformis, × 109 CFU/mL of Prevotella oralis, × 108 CFU/mL of Prevotella loescheii and × 104 CFU/mL of Candida albicans Susceptibilities of aerobes and anaerobes to antibiotics were performed for ... evaluation of treatment with newer quinolones after prolonged follow up J Antimicrob Chemother 1997, 39:241-246 Clinical and Laboratory Standards Institute: Performance Standards for Antimicrobial ... combination therapy [3] Because of the high probability of infection recurrence, our patient continued with high- dose oral ciprofloxacin (1 gram twice a day) for 20 months Repeat MRIs confirmed...
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Báo cáo y học: "Sarcoidosis mimicking lymphoma on positron emission tomography-computed tomography in two patients treated for lymphoma: two case reports" pptx
Ngày tải lên :
11/08/2014, 17:21
... segment and an ill-defined increase in parenchymal density The findings were interpreted as strongly likely to be recurrent lymphoma and the possibility of high- dose chemotherapy with autologous stem ... corresponding to cytotoxic T cell defect and increased T helper cell activity, has been reported to be consistent with defective cellular immunity [2] Increased T helper cell activity may represent ... the LN was highly suspicious for Hodgkin’s lymphoma (HL) The excisional biopsy of the LN revealed complete architectural effacement with scattered Reed-Sternberg (RS) cells, histiocytes and eosinophils...
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báo cáo khoa học: " Drug Checking: A prevention measure for a heterogeneous group with high consumption frequency and polydrug use - evaluation of zurich’s drug checking services" potx
Ngày tải lên :
11/08/2014, 18:20
... increased for alcohol, cannabis and cocaine (2004: 37.2% 11.6% and 10.1%, respectively; 2009: 43.0%, 16.8% and 11.5%, respectively) and decreased for ecstasy and amphetamines (2004: 19.5% and 19.4%, ... police and/ or medical-treatment services For example, thanks to the collaboration of the DIZ with a therapeutic and medical center (GAIN), a connection between a lowthreshold institution and a high- threshold ... cocaine (80.8%) and/ or amphetamines (74.8%) at least once in their life As shown in Figure 1, the initiation age for legal substances (alcohol and tobacco) was approximately 15 and the age for cannabis...
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Báo cáo y học: "The Nordic back pain subpopulation program: course patterns established through weekly follow-ups in patients treated for low back pain" pptx
Ngày tải lên :
13/08/2014, 14:20
... Pia Sørensen, and Kirsten Thorhauge a large thank you for their efforts Author details Nordic Institute of Chiropractic and Clinical Biomechanics, Clinical Locomotion Science, Forskerparken 10A, ... episode of LBP with or without sciatica as main complaint (i.e the patients had not seen the chiropractor for this specific pain episode previous to inclusion), 18 - 65 years, and having a mobile ... addition to the LBP, and inability to read or speak Danish Prior to inclusion, patients received written and verbal information about the study The project was presented for the local ethical...
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Novel III v mosfet integrated with high k dielectric and metal gate for future CMOS technology
Ngày tải lên :
16/10/2015, 15:37
... III-V MOSFET INTEGRATED WITH HIGH- K DIELECTRIC AND METAL GATE FOR FUTURE CMOS TECHNOLOGY Jianqiang Lin 2009 NOVEL III-V MOSFET INTEGRATED WITH HIGH- K DIELECTRIC AND METAL GATE FOR FUTURE CMOS TECHNOLOGY ... Lithography and Platinum hard mask It is V Summary demonstrated that 40 nm gate line can be achieved by this method, and high performance for small channel length MOSFET is reported As the platform for ... 28 Fig 2.9 : Normalized capacitance for two MOS systems (a) TaN/HfAlO/p-InGaAs and (b) TaN/HfAlO/p-GaAs Hysteresis is 0.4 V for InGaAs substrate for and 1.1 V for GaAs substrate Indium reduces...
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AN0877 devicenet™ group 2 slave firmware for PIC18 with CAN
Ngày tải lên :
11/01/2016, 14:34
... QS-9000 quality system certification for its worldwide headquarters, design and wafer fabrication facilities in Chandler and Tempe, Arizona in July 1999 and Mountain View, California in March 2002 ... return(1); case 3: // Set path and connection information return(1); case 4: // Set path and connection information return(1); case 5: // Set path and connection information return(1); } } 2003 ... variables and Explicit Message handling for the commands identified in Section 5-5 of the specification UsrDNet.c Logic that depends on the application is contained within this file; therefore, this...
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Báo cáo khoa học: Glycan profiling of urine, amniotic fluid and ascitic fluid from galactosialidosis patients reveals novel oligosaccharides with reducing end hexose and aldohexonic acid residues ppt
Ngày tải lên :
29/03/2014, 09:20
... urine samples, high levels of aldohexonic acid-containing glycans were often observed, with the exception of U4 (Table 3) In U1, U6 and U7, gluconic acid (o1) has high abundance, and high levels ... Center, The Netherlands) for kindly providing samples, Dr Cornelis H Hokke for fruitful discussions, Rob Bruggink for providing essential input for producing the capillary desalter, and Chris Pohl, ... of composition H2F1 (where F stands for deoxyhexose) and H2N1F1 (Table 2) Glycans with aldohexonic acid In addition, evidence was obtained from the LCMS ⁄ MS data for the presence of C1-oxidized...
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Báo cáo sinh học: " Research Article A New Switching-Based Median Filtering Scheme and Algorithm for Removal of High-Density Salt and Pepper Noise in Images" pptx
Ngày tải lên :
21/06/2014, 16:20
... identifies pixels corrupted by salt and pepper noise Salt and pepper noise produces two-level pixels, namely, and 255 and, therefore, identification is straightforward Stage employs a simple modified ... sample y j+1 is correlated with y j , and z j+1 is not correlated with y j which is a contradiction This is true for the subsequent elements in the sets Y and Z Therefore, x j+1 − zmed < x j+1 ... acceptable because x(n) has some correlation with previous data and, therefore, is a better candidate than an impulse After substitution, let x(n) be treated as an image pixel-free of impulse noise...
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Báo cáo hóa học: " Editorial Signal Processing with High Complexity: Prototyping and Industrial Design" docx
Ngày tải lên :
22/06/2014, 22:20
... Journal on Embedded Systems and is elected AdCom Member of EURASIP He authored and co-authored more than 200 papers and patents on adaptive filtering, wireless communications, and rapid prototyping ... communication systems at the University of Hannover, Germany, and is a founder of the spin-off company mimoOn GmbH He has published more than 100 papers and has co-edited four books on ultra-wideband and ... point, authors present and compare several tools and algorithms leading to an efficient fast prototyping framework Examples are given in the field of high- complexity communication systems but can be extended...
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Báo cáo y học: "Allogeneic hematopoietic stem cell transplantation for acute leukemia with Gilbert’s syndrome" pptx
Ngày tải lên :
10/08/2014, 21:23
... Bilirubin level during chemotherapy and allogeneic hematopoietic stem cell transplantation Chronological dates of the treatment courses were indicated (A) the first cycle of chemotherapy of DA regimen ... transaminase and bilirubin levels were almost normal during the conditioning and within 100 days after transplantation, although indirect hyperbilirubinemia repeatedly happened during chemotherapy with ... Allogeneic hematopoietic stem cell transplantation for acute leukemia with Gilbert’s syndrome Journal of Hematology & Oncology 2011 4:9 Submit your next manuscript to BioMed Central and take full advantage...
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báo cáo khoa học: " Integrated programs for women with substance use issues and their children: a qualitative meta-synthesis of processes and outcomes" potx
Ngày tải lên :
11/08/2014, 18:20
... Strategy A comprehensive and systematic literature search for studies of outcomes and processes associated with integrated intervention programs for women with substance use issues and their children ... specifically program participation and rapport with staff, was found to be associated with higher treatment motivation and readiness and to better psychosocial functioning (e.g., higher self-esteem, self-efficacy, ... treatment for women, Ashley, Marsden, and Brady [20] examined specific components of treatment programs and their association with outcomes Programs with prenatal care or childcare were associated with...
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Báo cáo y học: " Overcoming beta-agonist tolerance: high dose salbutamol and ipratropium bromide. Two randomised controlled trials" pps
Ngày tải lên :
12/08/2014, 15:20
... capsules for use with the Foradil Aeroliser (Novartis, Auckland, New Zealand) Additional beta-agonists were not allowed throughout the studies Ipratropium was used for symptom relief Study 1: High- dose ... of formoterol 120 100 80 60 40 placebo 20 formoterol ba se lin e po st -m 5m in s et ch ol in e 10 m in s 15 m in s 20 m in s Figure Response to high dose salbutamol (n = 11) Response to high dose ... guidelines Study 1: Does high dose salbutamol overcome the bronchodilator tolerance associated with regular long-acting beta-agonist use? Tolerance to the systemic [3] and bronchoprotective [4]...
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Báo cáo y học: " Lung development in laminin γ2 deficiency: abnormal tracheal hemidesmosomes with normal branching morphogenesis and epithelial differentiation" pdf
Ngày tải lên :
12/08/2014, 16:20
... paraformaldehyde for 10 minutes, washed in PBS, treated with 0.1 M glycine, pH 3.5, for 10 minutes, washed in PBS, treated with 0.1% SDS at 55°C for hour, washed in PBS, blocked, and stained as with ... compartments Endothelial cell and smooth muscle cell development were assessed with immunofluorescence staining for PECAM and α-smooth muscle actin, respectively As with the epithelial cell markers, no ... Antibodies were developed with DAB (Vector Laboratories) and counterstained with hematoxylin Antibody dilutions were 1:2500 for β-tubulin, 1:200 for CC26, and 1:5000 for SP-C Lung bud culture...
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Báo cáo y học: "Expression of infectious murine leukemia viruses by RAW264.7 cells, a potential complication for studies with a widely used mouse macrophage cell line" ppsx
Ngày tải lên :
13/08/2014, 06:20
... 264.7MuLVmix- and of 16 MoMuLV-induced tumors were non-lymphoid and diagnosed as erythroleukemia based on splenomegaly with a high frequency of erythroid cells and lack of reactivity with CD3 and PAX5 ... genotype of the mouse and the tropism of the virus Thus, Fv1n cells are permissive for N-tropic and partially restrictive for Btropic MuLVs; the reciprocal pattern is observed for cells of Fv1b mice ... between NIH Swiss and BALB/c recipients but virus dose was clearly an important variable for those inoculated with the viruses produced by RAW264.7 cells (264.7MuLVmix), with higher concentrations...
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