2 meta analysis of survival data

... 886 titles of potentially relevant articles from our search of computerized databases and 58 additional references from our manual search of the bibliographies of retrieved articles Of the 944 ... systematic review of reports of MTB infection in liver transplant recipients published between 1963 (the first report of a liver transplant) and 2007 to evaluate the effectiveness of pretransplant ... involvement), development of multiorgan MTB infection, development of isoniazid or rifampin hepatotoxicity, and presence of acute cellular hepatic rejection We adopted the definition of the Centers for...

Ngày tải lên: 29/03/2014, 03:20

... effect of H RA and sucralfate on ICU mortality In Figure Publication bias of the meta -analysis Publication bias for the outcome of ventilator-associated pneumonia in studies of the effects of histamine-2-receptor ... studies were categorized as ‘low risk of bias’, ‘unclear risk of bias’, or ‘high risk of bias’ Data extraction Two independent reviewers abstracted the data in a traditionalized format The following ... phase in the ICU Data synthesis Version 9.2 of the Stata program (StataCorp LP, College Station, TX, USA) was used for statistical analysis Data were analyzed by an intention-to-treat analysis, so...

Ngày tải lên: 13/08/2014, 21:21

... the case of linear estimators of the parameter of interest However, many methods of data analysis deal with more complex statistics In this section we show that the properties of many of these ... replaced by the conditional density of T given the actual survey data, i.e yobs , rs , iU and zU , and the joint marginal density of these data Analysis of Survey Data Edited by R L Chambers and ... error of b is expected to be smaller ^ than the design-based variance of b ^ Example illustrates that when the model holds, b may be better than ^ as an b estimator of b, from the point of view of...

Ngày tải lên: 14/08/2014, 09:20

... representation of the values for each of the cells of the studies is available from the authors upon request.) The next step was to conduct a standard × analysis of variance The analysis indicated ... does not offer an adequate explanation of the data There is evidence supportive of Sutton’s SEU model in the main effects and additive model tests There also is evidence supportive of the EPPM ... Severity NOTE: k = number of studies, N = number of research participants *p < 05 Main Effects of Message Features on Message Acceptance Dependent Variables Table shows that all of the message feature...

Ngày tải lên: 05/03/2014, 22:21

... Transformation of species data 19 1.12 Transformation of explanatory variables 20 METHODS OF GRADIENT ANALYSIS 22 2.1 Techniques of gradient analysis 22 2.2 Models of ... 84 8.2 Data 84 8.3 Data analysis 84 CASE STUDY 3: ANALYSIS OF REPEATED OBSERVATIONS OF SPECIES COMPOSITION IN A FACTORIAL EXPERIMENT: THE EFFECT OF FERTILIZATION, ... chapter 11 1.4 Response (species) data Our primary data (often called, based on the most typical context of the biological community data, the species data) can be often measured in a quite precise...

Ngày tải lên: 29/03/2014, 17:20

Ngày tải lên: 17/04/2014, 09:16

... results of the various studies and an estimate of the overall effect size of all the studies together considering the data available for each study included in the meta -analysis [25] Each line of ... intervals of the complete study analysis Discussion The aim of this study was to provide a comprehensive systematic review of the literature including a meta -analysis for estimated IQ data in AN ... obtained from normative data Studies included in this review were selected on the basis of quality of the data and validity of instruments used to Lopez et al Annals of General Psychiatry 2010,...

Ngày tải lên: 09/08/2014, 01:21

... age of 20 years Consequently, Figure B-HCC versus C-HCC: Results of the meta -analysis on 5-year disease-free survival All based on a random-effects meta -analysis Zhou et al World Journal of Surgical ... http://www.wjso.com/content/9/1/108 Page of 10 Figure B-HCC versus NBNC-HCC: Results of the meta -analysis on 5-year disease-free survival All based on a fixed-effects meta -analysis the mean age at occurrence of HCC is lower ... Journal of Surgical Oncology 2011, 9:108 http://www.wjso.com/content/9/1/108 Page of 10 Table Baseline characteristics of studies included in the meta -analysis Author Year Country Group No of patients...

Ngày tải lên: 09/08/2014, 02:21

... drafts of the paper RID Helped in data collection and tabulation and provision of data for survival analysis RW - Collection of data, wrote the manuscript in draft SKK -Contributed to drafts of the ... cancer have poor survival in the first twenty months after operation and predictable survival in the medium and long-term: Analysis of survival and prognostic markers World Journal of Surgical Oncology ... a mortality rate of 40% and 50% respectively compared to adenocarcinoma without mucin, 28% (p = 0.01) This was not significant in survival analysis however Univariate analysis of other prognostic...

Ngày tải lên: 09/08/2014, 03:22

... Meta -analysis of incidence of transiet nerve plasy (n patients) in total thyroidectomy with ultrasonic dissector of the first generation versus conventional clamp and tie Figure Meta -analysis of ... identification of trials, writing the text of review AS, GR, DV: Evaluation of methodological quality of trials, data collection RL, DG, AS: Literature search and identification of trials FS, ... dissector of the first generation versus conventional clamp and tie Cirocchi et al World Journal of Surgical Oncology 2010, 8:112 http://www.wjso.com/content/8/1/112 Page of Figure Meta -analysis of...

Ngày tải lên: 09/08/2014, 03:24

... Paracetamol 4,000 No data No data Rofecoxib 25 No data No data Naproxen 1,000 No data No data Diclofenac 100/150 331 2,325 14.2 (12.8–15.6) 593 2,325 25.5 (23.7–27.3) Ibuprofen 2,400 456 1,985 ... trials of to weeks, 88% of the doses were 200 mg daily In trials of 12 weeks' duration, 46% of doses were 200 mg and 46% were of 400 mg daily In trials of 24 weeks or longer, 92% of doses were of ... Diclofenac 2,400 14 345 4.1 (1.9–6.3) 37 345 10.7 (7.4–14) Placebo No data No data Celecoxib 100 No data No data Celecoxib 200 No data No data Celecoxib 400 26 326 8.0 (5.1–10.9) 34 326 10.4 (7.1–13.7)...

Ngày tải lên: 09/08/2014, 06:22

Ngày tải lên: 09/08/2014, 07:20

... any study, this is a rate of 0.2% over the course of an average treatment period of at least year Discussion Meta -analysis of small studies is problematic [63] because of possible inadequacies ... Outcomes of cohort studies All cohort studies Outcome Number of cohorts Only definite nephritis Number of Percentage events/patients with outcome Number of cohorts Any SLE patients Number of Percentage ... included patients with SLE, some of whom had lupus nephritis; of 284 patients studied, 63 had Table Outcomes of randomised trials Outcome Number of trials Number of patients Percentage with MMF...

Ngày tải lên: 09/08/2014, 08:23

... with p value of 0.45, which indicates that the pooling of the data was valid (Figure 6) Quality of studies The RCT quality scores was of point (5-point scale), the median score was of with none ... due to use of tamoxifen alone or in association with radiotherapy The characteristics of RCTs how: duration of the study, total dose and fractionation of RT, median follow up, number of patients, ... all of the trials of 1.08 with a 95% confidence interval of 0.65 to 1.78 The test for heterogeneity was not statistically significant with p value 0.93, which indicates that the pooling of the data...

Ngày tải lên: 09/08/2014, 10:21

... the currently available data [26] It has been suggested that a minority of RA patients (those with the worst disease) carry much of the increased risk of lymphoma because of their disease rather ... relative risk of 7.4 for Hodgkin lymphoma Sources of selection bias may include the use of hospitalization records for identification of populations Other limitations include the possibility of misclassification ... misclassification of the inclusion of patients into the RA populations, and there may have been uncertainty surrounding the diagnostic accuracy of the malignancies Several of the studies were dependent on database...

Ngày tải lên: 09/08/2014, 10:23

... the process of study selection selection Data abstraction A data abstraction form was created and the following data were included: number of patients and controls, gender (percentage of women), ... time of evolution of the disorder (years), severity of the disorder, level of health care (primary care or specialised), kind of treatment (pharmacological or non pharmacological), duration of ... quality of the included studies Only 11 of the 33 included studies (33.3%) showed a rating of 5+ on the modified Oxford Scale, that is, a score of high methodological quality Most of them (nine of...

Ngày tải lên: 09/08/2014, 10:23

... 55% and DLCO < 40% of predicted) have a worse prognosis, with a mortality of 42% within 10 years of the onset of disease [5] A number of agents have been evaluated for treatment of SScrelated ILD ... abstract databases of the annual scientific meetings of the European League Against Rheumatism, the American College of Rheumatology and the American Thoracic Society, from the approval of CYC ... standard error data We therefore imputed the mean value of the standard errors of the other studies, and performed sensitivity analyses across the range of reported standard errors of these studies...

Ngày tải lên: 09/08/2014, 13:22

... the present analysis Thirty-five trials were included in the present analysis, with a total of 9, 979 patients accrued Characteristics of the eligible trials are listed in Table Most of the trials ... al Journal of Hematology & Oncology 2011, 4:11 http://www.jhoonline.org/content/4/1/11 Page of 15 Table Characteristics of the eligible trials included in the meta -analysis Trial No of pts Gong ... including 4465 patients for the analysis of OS The analysis revealed a significant survival benefit for gemcitabine+X (X = cytotoxic agent) with a pooled ORs of 0.91 (p = 0.004) and indicated...

Ngày tải lên: 10/08/2014, 21:23

... review and meta -analysis to assess the overall treatment efficacy and the adverse events of the CAG regimen Materials and Methods Data source The databases of PubMed, Wanfang Data, as well as ... studies All deaths of any cause within weeks of induction therapy were counted as ED in this meta -analysis since most of the early death reports in this series were within weeks of induction therapy ... kinds of leukemia were also excluded A total of 35 clinical studies were eligible for inclusion and were used for final metaanalysis (Figure 1) Characteristics of studies included in the meta-analysis...

Ngày tải lên: 10/08/2014, 21:23

... 26% of the US population It is the only comprehensive source of population based data in the U.S that includes the stage of cancer at the time of diagnosis and follow-up of all patients for survival ... in the database limiting our analysis on diagnostic accuracy of MRI, and prognostic significance of absence of myeloma protein, anemia, hypercalcemia, renal insufficiency and stability of M-protein ... validated national database The current study also reiterates the need of better understanding of the disease process of plasma cell neoplasm and the inclusion of molecular markers in the database Competing...

Ngày tải lên: 10/08/2014, 22:20