2 immunomodulatory properties of hucbcs
Báo cáo khoa học " In vitro cytostatic and immunomodulatory properties of the medicinal mushroom Lentinula edodes " pdf
Ngày tải lên :
28/06/2014, 11:20
... components of mannoglycans and mannoproteins of fungal cell walls (Kim et al., 2003; Peng et al., 2003) The FT-IR spectra (Fig 1) of lentinan samples showed the presence of considerable amount of proteins ... measured by incorporation of [3H]-thymidine expressed in counts per minute (cpm) In each of at least two experiments, means of the counts per minute (cpm) for each set of replica experiments were ... characteristics of the extracts isolated from the fruit body and mycelium of L edodes are listed in Table The glucose content, indicating the presence of glucan-type polysaccharides, is higher in the case of...
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Báo cáo y học: "Immunomodulatory properties of mesenchymal stem cells: a review based on an interdisciplinary meeting held at the Kennedy Institute" potx
Ngày tải lên :
09/08/2014, 08:23
... protection by expression of HLA class I molecules on the MSCs Several speakers addressed the issue of the role of soluble factors in the immunomodulatory properties of MSCs Human MSCs caused ... question of the role of the antiproliferative effect in the control of tissue organization and maintenance [48] Nico Wulffraat reported that local delivery of adult MSCs improved the regeneration of ... exploitation of MSCs One major problem is the lack of a commercial Good Manufacturing Practice licensed MSC product There are no generally accepted assays of the potency of MSCs, and the optimal route of...
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Báo cáo y học: "Immunomodulatory properties of human adult and fetal multipotent mesenchymal stem " pptx
Ngày tải lên :
10/08/2014, 05:21
... immunomodulation of adult BMMSCs and F-MSCs, properties which appear increasingly relevant for clinical use Interactions of BMMSCs and F-MSCs with subpopulations of leukocytes, and mechanisms of actions–when ... presence of BMMSCs, the differentiation of CD14+ monocytes into DCs is impaired, and the monocytes retain high expression of CD14 +–a marker of immaturity for DCs–without the upregulation of CD1a, ... of BMMSCs and immunosuppressive drugs can prolong organ allograft survival [135,136] Because of the profound immunomodulatory effect of BMMSCs shown in vitro and in vivo, co-transplantation of...
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Immunomodulatory properties of polysaccharide protein complex from lycium barbarum l
Ngày tải lên :
11/09/2015, 16:03
... Limulus assay 96 xii List of Figures LIST OF FIGURES Figure T cell activation pathway 47 Figure Elution profile of LBP on DEAE-cellulose column (OH-) 88 Figure Elution profiles of LBP1-5 on Sephacryl ... understanding and endless love iii Table of Contents TABLE OF CONTENTS ACKNOWLEDGEMENTS ii TABLE OF CONTENTS iii SUMMARY viii LIST OF TABLES xi LIST OF FIGURES xii ABBREVIATIONS xiv CHAPTER INTRODUCTION ... Purification and Characterization of LBP 83 84 3.1.1 Aim of Study 84 3.1.2 Results 84 3.1.2.1 Isolation of LBP 84 3.1.2.2 Purification of LBP 85 3.1.2.3 Characterization of LBP on Carbohydrate and Protein...
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Tài liệu Báo cáo khoa học: The antibacterial and antifungal properties of trappin-2 (pre-elafin) do not depend on its protease inhibitory function pptx
Ngày tải lên :
18/02/2014, 17:20
... inhibitory properties, we show that the antibacterial ⁄ fungicidal action of trappin-2 is independent of its antiprotease function Although we have not determined its exact mechanism of action, ... that the antibacterial ⁄ fungicidal properties of trappin-2 involve the cationic nature of the molecule, as assessed from the salt and heparin dependence of the antimicrobial and antifungal effects ... lane for elafin) (B) Effect of class-specific protease inhibitors pepstatin (Peps., inhibitor of aspartyl proteases), AEBSF (inhibitor of serine proteases), E64 (inhibitor of cysteine proteases) and...
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Tài liệu Báo cáo Y học: Kinetic properties of bifunctional 6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase from spinach leaves pdf
Ngày tải lên :
22/02/2014, 04:20
... the ratio of 6PF2K activity to Fru-2,6-P2ase activity of the smaller form of the bifunctional enzyme was far lower than that of the larger form of the enzyme [11] This is reminiscent of the enzyme ... vivo concentration of each of these metabolites and of Pi, as discussed previously [1] In conclusion, the kinetic properties of the recombinant enzyme are in agreement with those of the enzyme isolated ... demonstrable effects of proteolysis on the kinetic characteristics of the component activities of the enzyme compromise the evidence on which our current understanding of the regulation of photosynthetic...
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Báo cáo khoa học: Enzymes of mannitol metabolism in the human pathogenic fungusAspergillus fumigatus– kinetic properties of mannitol-1-phosphate 5-dehydrogenase and mannitol 2-dehydrogenase, and their physiological implications pot
Ngày tải lên :
14/03/2014, 23:20
... Af M2DH Interpretation of the kinetic properties of an enzyme in the context of its role in cellular metabolism relies on knowledge of the physiological concentrations of substrates, products, ... intracellular concentration of Fru is about two orders of magnitude below the apparent Km of 40 mm A physiological role of AfM2DH in the utilization of intracellular Man-ol via reversal of path in Scheme ... comparison of polyol substrates of AfM2DH Fig S2 Comparison of the structural model of AfM2DH with the experimentally determined crystal structure of PsM2DH (1lj8) Fig S3 Kinetic analysis of inhibition...
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Báo cáo khoa học: Role of the structural domains in the functional properties of pancreatic lipase-related protein 2 pot
Ngày tải lên :
16/03/2014, 06:20
... presence of NaTDC (data not shown) In the case of NcC2, no inhibition of the lipase activity was observed, as 100% of the lipase activity still remained even at a molar excess of 45 The effect of NcC2 ... The properties of the chimeras were compared to those of the original proteins bearing the modifications induced by the constructions in the chimeric proteins and compared with the properties of ... N-terminal and C-terminal domain sequences of each protein The chimeric protein composed of the N-terminal domain of hoPL and of the C-terminal domain of hoPLRP2 was named NcC2 Conversely, the...
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Báo cáo khoa học: Investigation of leucine-rich repeat kinase 2 Enzymological properties and novel assays pptx
Ngày tải lên :
23/03/2014, 06:20
... 20- Fig Characterization of LRRK2 proteins (A) Coomassie Bluestained gel of lg of each GST–LRRK2 protein preparation separated by SDS ⁄ PAGE (B) Western blot of 0.5 lg of wild-type (WT) LRRK2 ... constructs, consisting of either the kinase or COR-kinase domains of LRRK2 Baculovirus-mediated production of proteins gives the advantage of being able to produce large amounts of post-translationally ... relevant substrates of LRRK2 has led to the identification of members of the ezrin– radixin–moesin family of proteins [14] as potential substrates Although the physiological relevance of these proteins...
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Báo cáo khoa học: Odorant binding protein has the biochemical properties of a scavenger for 4-hydroxy-2-nonenal in mammalian nasal mucosa doc
Ngày tải lên :
23/03/2014, 10:20
... characterization of the reversible binding complex between OBP and HNE; (b) investigation of the chemical modifications of OBP as a result of incubation with large excesses of HNE and evaluation of their ... Evaluation of the protective role of OBP against HNE cytotoxicity in a simplified model simulating the nasal epithelium The aim of this experiment was a preliminary evaluation of the protective role of ... peroxidation of unsaturated fatty acids This study was realized through characterization of the binding properties and chemical resistance of OBP to HNE, an alken-aldehyde involved in the pathogenesis of...
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Materials Science and Engineering - Electronic and Mechanical Properties of Materials Part 2 pot
Ngày tải lên :
11/08/2014, 14:20
... p0 = p0 − eE τ ω>>1/τ, p out of phase with E eE0 p0 = iω − τ eE0 iω ω → ∞, p → ω1/τ) p p (ω
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Mechanical Properties of Engineered Materials 2008 Part 2 pps
Ngày tải lên :
11/08/2014, 15:20
... macroscopic level of understanding of structure [Figs 16(a)–(d)] They are often unaware of the atomic and microstructural constituents that can affect the mechanical behavior of materials and of the role ... symmetry of the crystal An example of a two-dimensional unit cell is shown in Fig 1.10(a) This illustrates the two-dimensional layered structure of graphite which is one of the allotropes of carbon ... mechanical properties of semiconductor devices has thus emerged as one of the fastest growing areas in the field of mechanical behavior Copyright © 2003 Marcel Dekker, Inc FIGURE 1.13 Microstructures of...
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Báo cáo y học: " Dimensionality and scale properties of the Edinburgh Depression Scale (EDS) in patients with type 2 diabetes mellitus: the DiaDDzoB study" pot
Ngày tải lên :
11/08/2014, 15:22
... measurement properties of the questionnaire and its constituent items One of the valuable features of IRT modeling is the possibility of evaluating the test and item reliability at different ranges of ... http://www.biomedcentral.com/1471-244X/11/141 Page 15 of 19 (a) Expected Item Score 2.5 1.5 Cutoff Cutoff 12 0.5 10 Item Number (b) Expected Item Score 2.5 1.5 Cutoff Cutoff 12 0.5 10 Item Number Figure Expected item-score profiles, for ... ranges of the θ scale To evaluate the screening properties of the EDS and its constituent items in more detail, the cutoff scores on the X+ scale had to be translated into corresponding cutoffs...
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Mechanical properties of polymers, composites-Nielsen 2010 Part 2 potx
Ngày tải lên :
12/08/2014, 03:20
... yield point and is typical of a material that cold-draws with necking down of the cross section in a limited area of the specimen Curves of the third graph (C) arc typical of elastomeric materials ... different types of apparatus arc capable of covering the range from a small fraction of a cycle per second up to millions of cycles per second Most instruments measure either shear or tensile properties, ... diagrams of various types of tensile tests F, force; e strain or elongation sures over a period of time the deformation brought about by a constant load or force, or for a true measure of the response,...
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Báo cáo khoa học: " Characterization of the RNA-binding properties of the triple-gene-block protein 2 of Bamboo mosaic virus" pdf
Ngày tải lên :
12/08/2014, 04:21
... molar ratio of viral RNA to TGBp2 of 0.35:1) or absence of viral RNA before measurement of tyrosine fluorescence C Effect of viral RNA concentration on the intrinsic tyrosine fluorescence of Triton ... non-viral Figure The RNA-binding properties of unfused TGBp2 The RNA-binding properties of unfused TGBp2 A Effect of salt concentration on the RNA-binding activity of unfused TGBp2 After UV-crosslinking ... tail (residue 105) of His6-TGBp2 with alanine and analyzed the effects of these mutations on RNA binding of His6-TGBp2 No significant effect of tyrosine mutation on RNA binding of His6-TGBp2 was...
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Mechanical properties of polymers and composites-Nielsen Episode 2 pot
Ngày tải lên :
13/08/2014, 16:21
... yield point and is typical of a material that cold-draws with necking down of the cross section in a limited area of the specimen Curves of the third graph (C) arc typical of elastomeric materials ... different types of apparatus arc capable of covering the range from a small fraction of a cycle per second up to millions of cycles per second Most instruments measure either shear or tensile properties, ... diagrams of various types of tensile tests F, force; e strain or elongation sures over a period of time the deformation brought about by a constant load or force, or for a true measure of the response,...
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DESIGN, SYNTHESIS AND PROPERTIES OF METAL COMPLEXES AND COORDINATION POLYMERS FOR 2+2 PHOTO CYCLOADDITION REACTIONS
Ngày tải lên :
09/09/2015, 11:15
... OF CONTENTS Declaration II Acknowledgements III Table of Contents VI Summary XII List of Tables XV List of Figures XVI List of Schemes XXII List of Abbreviations XXIII Publications XXV List of ... transformation of 2D interdigitated MOF, V-1.2 5.1-12 to doubly interpenetrated 3D MOF, V-1.3 Figure 5.1- Comparison of PXRD data of V-1.2 & V-1.3 5.1-13 Figure 5.1- 10 A perspective view of a portion of ... Comparison of PXRD patterns of III-2 and III-2 3-12 Figure 3-10 Time versus percentage conversion plots of ground 3-13 powder of III-1, III-4, single crystals of III-1, III-4 Figure 3-11 Comparison of...
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Magnetic properties of hybrid nanostructures 2
Ngày tải lên :
11/09/2015, 10:01
... To study the magnetic properties of materials dispersed in solution require recovery of sub-grams quantities of the material in powder form, with inevitable coagulation of the nanomaterials In ... part of the work, we focused our attention on a monolayer of colloidal crystals The schematic in Figure 3.4 shows the process of creating magnetic hemispherical caps of FePt The monolayer of colloidal ... Measurement of remanence curves Figure 4.1 Measurement of remanence curves Measurement of remanence determines only the irreversible component of 88 magnetization and thus enables the phenomena of switching...
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Processing and mechanical properties of pure mg and in situ aln reinforced mg 5al composite 2
Ngày tải lên :
14/09/2015, 14:10
... the crystal size of which is of the order of a few (typically 1-100) nanometers in at least one dimension Because of the extremely small size of the grains, a large fraction of the atoms in these ... important role to alter the properties of bulk nc materials 2.3 Mechanical behaviours of nanocrystalline materials For understanding of the mechanical properties of nanophase materials in general, ... the strength of MMed materials However, the amount of impurity increases with milling time, leading to degradation of overall combination of mechanical properties Consolidation of the fine powders...
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