... T, Nakanishi K, Shimada A, Uga M, Kurihara S, Kawabata Y, et al: Genetic association between the interleukin-2 receptor-alpha gene and mode of onset of type diabetes in the Japanese population ... polymorphisms in the IL2RA gene are associated with age at diagnosis in late-onset Finnish type diabetes subjects Immunogenetics 2010, 62:101-107 36 Kawasaki E, Awata T, Ikegami H, Kobayashi T, Maruyama ... immune tolerance requires a finely controlled balance between maintaining tolerance to self-antigens and mounting protective immunity against enteric and invading pathogens [1] Self-reactive T cells...
Ngày tải lên: 18/06/2014, 16:20
... 150 mM NaCl, 1% v/v NP40, mM EDTA) containing 10 μg/ml pepstatin/aprotinin/leupeptin, mM sodium orthovanadate and mM NaF After removal of insoluble material by centrifugation at 10.000 × g and 4°C ... additionally verified this by measuring the activities of the initiator-caspase and the effector-caspase As shown in Fig 1A, no caspase activity over background was detectable in TNF/CHX/zVAD-treated ... ROS, PARP, NAD+/ATP-depletion, AIF, ROS, PARP, NAD+/ATP-depletion, AIF, Cathepsins, Calpains, EndoG, HtrA2/OMI Cathepsins, Calpains, EndoG, HtrA2/OMI ciPCD Figure ciPCD the ER and mitochondria in...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "Excess circulating angiopoietin-2 is a strong predictor of mortality in critically ill medical patients"
... model In a large trauma cohort study [22], Ang2 correlated with mortality in a univariate analysis In a surgical population with ARDS, Ang-2 predicted death with a similar discriminatory ability as ... data reveal an important limitation for Ang-2 as a quantitative marker for vascular permeability: high Ang-2 might be a surrogate parameter for increased capillary permeability per se, but is a ... obtained at the time of enrollment Detailed patients' characteristics, including demographic, clinical and laboratory parameters, are shown in Table Controls Twenty-nine age- and gender-matched...
Ngày tải lên: 25/10/2012, 10:31
Tài liệu Using the Data Form Wizard to Create a Windows Form phần 2 doc
... and add the following Main() method inside your MyDataForm class (a good place to add Main() would be at the start of your MyDataForm class after the open curled bracket {): public class MyDataForm ... property in the DataBindings group The Text property in the DataBindings group sets the text displayed in a control To examine or set the data binding for a control, you select the control in the ... managed provider classes in the System.Data.SqlClient namespace were used instead; these classes are specifically for use with a SQL Server database This is the price of having the VS NET wizard...
Ngày tải lên: 24/12/2013, 01:17
ADOBE DIRECTOR 11.0 CREATE A BASIC MOVIE IN DIRECTOR DI pdf
... markers in the Score and send the playhead to a marker rather than a specific frame number ADOBE DIRECTOR 11.0 28 Create a basic movie Markers are a way of giving a name to a specific frame in the ... marker, type Animation, and press Enter (Windows) or Return (Macintosh) to name the marker Create navigation in Lingo using marker names You can write a script that loops the playhead in frames ... sprites and cast members As you learned earlier in this tutorial, when you drag cast members onto the Stage, you create sprites Sprites are instances of cast members that appear on the Stage and in...
Ngày tải lên: 24/03/2014, 01:20
Lesson 2 Working with data in a connected environment
... Load only a single row into memory at a time Only one DataReader use at a time Tie to connection => cannot used other DataReader Explicitly close DataReader after used DataReader cannot ... environment Windows Database Connection Command DataReader Form Slide Features of DataReader A type that is good for reading data in the most efficient manner possible Read-only, forward-only ... sequentially read data from a data source The return results of Command SQL statements (no constructor) How to use DataReader with data providers? How to retrieving data using a DataReader?...
Ngày tải lên: 13/05/2014, 12:19
báo cáo hóa học:" Identification of a public CDR3 motif and a biased utilization of T-cell receptor V beta and J beta chains in HLA-A2/Melan-A-specific T-cell clonotypes of melanoma patients" potx
... CAGCCCCAGCA T .TATGGCTACACC .CAGCCCCAGCA T .CAGCCCCAGCA T .CAGCCCCAGXX X .CAGCCCCAGXX X .CAGCCCCAGCA T TTCACCCCT CCAC TCAGCCCCAGXX X TCAGCCCCAGXX X TCAGCCCCAGCA T .CAGCCCCAGCA T .CAGCCCCAGCA ... CAGGGGGC TCGG 42 GCCAGCAGT G T .ACAGGGG CTCGG D/b GCCAGTAGTAT GACAGGG CTAGGG AGTGC GCCCGAT .ACAGGG CTTGGC GCCAGCAG ATACCA GGGAC TAGGA 39 GCCTGGAGTGT C C CAGGG CTAGG NA XXXXXXAGT CAT CAGGG ... cNA: ID not available; dm: modified Melan -A A27L; eClonotype was obtained from one T- clone was obtained before and one after vaccination; fX: amino acid not available; gn: natural Melan -A In...
Ngày tải lên: 18/06/2014, 15:20
ON THE ALGEBRAIC DIFFERENCE EQUATIONS un+2 un = ψ(un+1 ) IN R+ , RELATED TO A FAMILY ∗ OF pdf
... corresponding set of values of parameters Precisely, we will say that “an integer k is minimal period” if there exist values (b,c,d) in this set of parameters of the table and an initial point (u1 ... birational transformation of the quartic We know that the quartic curve has two double points at in nity in vertical and horizontal direction, which are ordinary if d2 − 4c = 0, the asymptotes being ... (1.2) has IPCB If c < 1, we make the same reasoning, mutatis mutandis (e) Finally, we look at the case when (bc − d)(cd − b) < So N(g ) has a negative and a positive roots G Bastien and M Rogalski...
Ngày tải lên: 23/06/2014, 00:20
Giáo án Anh văn lớp 7 : Tên bài dạy : Unit 9 : At home and away. Lesson 2: A2- A holiday in Nha trang. pps
... reading -Play the tape twice , and ask the Ss to read the text in silence to find out the content of the reading - Ask the Ss to read the text aloud - Read the answer in pairs aloud a Her parents ... to the Aquarium b They saw sharks , dolphins , turtles and many colour fish c There was a sourvenirs shop near the exsit of the aquarium d Mr Robinsons bought a cap and a poter After that, they ... listening and reading - Ask the Ss to read the text again , and look at the picture to retell the story of Liz‘s family ( work in pairs ) - Aks the Ss to retell the story in front the class a The...
Ngày tải lên: 06/08/2014, 16:20
Báo cáo khoa học: "Leaf gas exchange and carbohydrate concentrations in Pinus pinaster plants subjected to elevated CO 2 and a soil drying cycle" doc
... Starch and soluble carbohydrates in leaves of water-stressed oak saplings, Ann Sci For 53 (1996) 263-268 [6] Granier A. , Loustau D., Measuring and modelling the transpiration of a maritime pine ... roots of P pinaster seedlings grown in mineral solution, as it was also mentioned by Popp and Smirnoff [ 14] in Cajanus cajan Can results obtained in such conditions extrapolate to more realistic ... under ambient [CO ] In a previous experiment on P pinaster [12], the stimulation of CO assimilation rate under elevated [CO ] was maintained along a drying cycle, but leaf carbohydrate concentrations...
Ngày tải lên: 08/08/2014, 14:21
Báo cáo y học: "Validation of a specific measure to assess healthrelated quality of life in patients with schizophrenia and bipolar disorder: the ‘Tolerability and quality of life’ (TOOL) questionnaire" doc
... group Data tabulation, database validation and the statistical analyses were carried out using the statistical packages SPSS (version 14.0; SPSS, Chicago, IL, USA) and Stata (version 10.0; Stata, ... Salamanca, Salamanca, Spain 2Department of Psychiatry, Hospital del Henares, Coslada, Madrid, Spain 3BAP Health Outcomes Research, Oviedo, Spain 4Value Demonstration Unit, AstraZeneca Medical Department, ... statistical analyses All authors made meaningful contributions to data interpretation ALM, JC, and JM cowrote the final draft of the manuscript All authors read and approved the final manuscript...
Ngày tải lên: 09/08/2014, 01:21
Báo cáo y học: "Association of a specific haplotype across the genes MMP1 and MMP3 with radiographic joint destruction in rheumatoid arthritis" ppt
... It evaluates 38 joints separately (all proximal interphalangeal and metacarpophalangeal joints, four sites in the wrists, interphalangeal joints of the great toes, and metatarsophalangeals to ... Kanamori Y, Matsushima M, Minaguchi T, Kobayashi K, Sagae S, Kudo R, Terakawa N, Nakamura Y: Correlation between expression of the matrix metalloproteinase-1 gene in ovarian cancers and an insertion/deletion ... Terashima M, Akita H, Kanazawa K, Inoue N, Yamada S, Ito K, Matsuda Y, Takai E, Iwai C, Kurogane H, Yoshida Y, Yokoyama M: Stromelysin promoter 5A/ 6A polymorphism is associated with acute myocardial...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "First-dose analgesic effect of the cyclo-oxygenase-2 selective inhibitor lumiracoxib in osteoarthritis of the knee: a randomized, double-blind, placebo-controlled comparison with celecoxib [NCT00267215]" doc
... statistical analysis, KJB was Medical Advisor for Germany (participating in study design and coordination) and UT was the pain clinical programme leader (participating in study design and coordina- Page ... analysis PID was analysed using analysis of covariance (ANCOVA) The statistical fixed-effects model considered treatment and centre as main effects, whereas baseline actual pain was used as a ... WOMAC™ scores (mean ± SD) aVAS actual pain intensity = mean of 3-hour and 5-hour assessments bVAS worst pain intensity = worst pain intensity in the past 12 hours cVAS average pain intensity = average...
Ngày tải lên: 09/08/2014, 07:20
Extracellular signal-regulated kinase 1/2 plays a pro-life role in experimental brain stem death via MAPK signal-interacting kinase at rostral ventrolateral medulla pps
... Pharmacological blockade was again used to ascertain that these temporally correlated biochemical changes are causally linked to MEK1/2 or ERK1/2 activation in RVLM during experimental brain ... Bonventre JV, Alessandrini A: Intravenous administration of MEK inhibitor U0126 affords brain protection against forebrain ischemia and focal cerebral ischemia Proc Natl Acad Sci USA 2001, 98:11569-11574 ... At the same time, as the origin of a life-and-death signal [5] that reflects failure of the central cardiovascular regulatory machinery during brain stem death [6-8] and a brain stem site via...
Ngày tải lên: 10/08/2014, 05:21
báo cáo khoa học: "Atypical epigenetic mark in an atypical location: cytosine methylation at asymmetric (CNN) sites within the body of a non-repetitive tomato gene" ppsx
... same conditions indicated above, using the following primers: Asr1 337 bp 5’-CAGATGGAGGAGGAGAAACAC-3’ 5’-TAGAAGAGATGGTGGTGTCCC-3’ Actin 185 bp 5’-GGGATGATATGGAGAAGATATGG-3’ 5’-AAGCACAGCCTGGATAGC-3’ ... methylation in ribosomal RNA genes of Arabidopsis thaliana BMC Plant Biol 2008, 8:92 38 Miura A, Nakamura M, Inagaki S, Kobayashi A, Saze H, Kakutani T: An Arabidopsis jmjC domain protein protects transcribed ... glycine-betaine Planta 2008, 227:1213-1219 Maskin L, Frankel N, Gudesblat G, Demergasso MJ, Pietrasanta L, Iusem ND: Dimerization and DNA-binding of ASR1, a small hydrophilic protein abundant in...
Ngày tải lên: 11/08/2014, 11:20
báo cáo khoa học: "Loss-of-function mutations affecting a specific Glycine max R2R3 MYB transcription factor result in brown hilum and brown seed coats" docx
... Tawny Naringenin 5’ OH Eriodictoyl leucodelphinidin DFR leucopelargonidin leucocyanidin ANS cyanidins LAR delphinidin pelargonidin cyanidin UF3GT (activated by R) ANR anthocyanins Delphinidin-3-glycoside ... utilizing a coffee grinder to generate a fine powder The grinder was cleaned thoroughly between grindings DNA was isolated using a DNeasy Plant Maxi Kit (Qiagen, Inc., Valencia, CA) according to manufacturer’s ... 10(1):14 60 Palapol Y, Ketsa S, Lin-Wang K, Ferguson I, Allan A: A MYB transcription factor regulates anthocyanin biosynthesis in mangosteen (Garcinia mangostana L.) fruit during ripening Planta 2009,...
Ngày tải lên: 11/08/2014, 11:21
báo cáo khoa học: " Light has a specific role in modulating Arabidopsis gene expression at low temperature" potx
... J, Narusaka M, Fujita M, Nanjo T, Umezawa T, Kamiya A, Nakajima M, Enju A, Sakurai T, Satou M, Akiyama K, YamaguchiShinozaki K, Carninci P, Kawai J, Hayashizaki Y, Shinozaki K: Monitoring the ... Seki M, Nanjo T, Narusaka M, Fujita M, Satoh R, Satou M, Sakurai T, Ishida J, Akiyama K, Iida K, Maruyama K, Satoh S, Yamaguchi-Shinozaki K, Shinozaki K: Monitoring expression profiles of Arabidopsis ... (SANT Domain) At2g03340 WRKY family transcription factor At3g61260 DNA-binding protein-related DNA-binding protein (dbp) At3g16770 AP2 domain transcription factor RAP2.3 At2g25900 CCCH-type zinc...
Ngày tải lên: 12/08/2014, 05:20
Báo cáo y học: " Involvement of TORC2, a CREB co-activator, in the in vivo-specific transcriptional control of HTLV-1" doc
... elongation factor (EF)-1α, 5'-TCTGGTTGGAATGGTGACAACATGC-3' and 5'-CCAGGAAGAGCTTCACTCAAAGCTT-3'; for GAPDH, 5'ACCACAGTCCATGCCATCAC-3' and 5'-TCCACCACCCTGTTGCTGTA-3'; for β-actin: 5'-GAGATCTGCCGATCCGCCGCCCG-3', ... Y, Yasunaga J, Nosaka K, Tanaka Y, Matsuoka M: Genetic and epigenetic inactivation of tax gene in adult T-cell leukemia cells Int J Cancer 2004, 109:559-567 Kannagi M, Harada S, Maruyama I, Inoko ... 5'-ACGCCTATGATTTCCGGGCC-3' and 5'-GGATATTTGGGGCTCATGGTCA-3'; for CD4, 5'-CAGAGCCTGACCCTGACCTTG-3' and 5'CATCACCACCAGGTTCACTTCC-3'; for endogenouse mouse retroviral env, 5'-GAAGGTCCAGCGTTCTCAAAAT-3' and 5'-CACGTGATTTCACTTCTTCTGG3'[47];...
Ngày tải lên: 12/08/2014, 23:21
Báo cáo y học: "HIV-1 Vpu and HIV-2 Env counteract BST-2/tetherin by sequestration in a perinuclear compartment" pot
... present at the cell surface and in a perinuclear compartment It has been suggested that tetherin could retain viruses at the cell surface by physically linking viral and plasma membranes [3,22] A correlate ... of tetherin to an intracellular compartment by HIV anti-tetherin factors (A) The percentage of HeLa cells displaying tetherin concentrated in a perinuclear compartment (PNC) was calculated for ... Southern California, Los Angeles, California, USA, 2Department of Medicine, University of California San Diego, La Jolla, California, USA and 3San Diego Veterans Affairs Healthcare System, San Diego,...
Ngày tải lên: 13/08/2014, 01:20
Báo cáo y học: "Pain patterns and descriptions in patients with radicular pain: Does the pain necessarily follow a specific dermatome" doc
... strength in that the description of each patient's pain pattern was recorded by the examining clinician in the manner that is normally carried out in clinical practice, rather than as part of a research ... drawing in the evaluation of low back pain Int Orthop 1995, 19(6):361-6 Ohlund C, Eek C, Palmbald S, Areskoug B, Nachemson A: Quantified pain drawing in subacute low back pain Validation in a ... pain - that can arise from one of more spinal nerve roots [14] Accurate diagnosis of patients with spine-related pain is increasingly being recognized as important in helping clinicians make individual...
Ngày tải lên: 13/08/2014, 14:20