18f fdg pet ct in adrenocortical carcinoma

... spiral CT The superiority of PET/ CT, a metabolic imaging tool, over CT in the preoperative N staging is marked in this case In the literature, although PET/ CT does not have a role in T staging in ... gastrointestinal tract by using noninvasive imaging methods (US, CT, MR imaging, PET) : a metaanalysis Radiology 2002, 224(3):748-756 Lynch TB: Introduction PET/ CT in Clinical Practice Springer-Verlag London; ... imaging tools But the role of 18F- Fluorodeoxyglucose (FDG) -PET/ CT in the diagnosis of distant lymph node, bone or lung metastasis is uncertain [8] 18F- FDG- PET is a functional imaging method detecting...

Ngày tải lên: 09/08/2014, 02:20

... including visual comparisons, image overlays, fusion of PET and CT images, and PET/ CT simulation Since there is less co-registration error between PET and CT using the same DICOM coordinates, PET/ CT ... listed in Table PET- CT image acquisition All patients were asked to fast for at least hours before 18 F -FDG PET/ CT imaging Approximately 60 minutes after the administration of 370 MBq of 18F- FDG, ... Tirona R: The impact of (18 )FDG- PET on target and critical organs in CTbased treatment planning of patients with poorly defined non-small-cell lung carcinoma: a prospective study Int J Radiat Oncol...

Ngày tải lên: 09/08/2014, 09:20

... GTVs were contoured on CT images obtaining CT- GTV, PET (PET- GTV), and PET/ CT images (PET/ CTGTV) The PET/ CT- GTV included both PET and CT information The clinical target volume (CTV), for treatment ... PET and CT; "PEToutCT" is the volume identified by PET but not by CT; "CToutPET" is the volume identified by CT but not by PET; "CT &PET" is the common volume of PET and CT Results Tumor staging ... Abbreviations: PET/ CT- GTV: the composite volume between PET and CT; PEToutCT: the volume identified by PET but not by CT; CToutPET: the volume identified by CT but not by PET; CT &PET: the common...

Ngày tải lên: 09/08/2014, 09:22

... 56-year-old man with coughing three months FDG PET / CT was performed, and resection specimens of lung and thyroid were detected by hematoxylin eosin staining (HE) and IHC PET / CT: lung tumor SUVmax: ... staining, but the lining cells in pulmonary papillary adenocarcinomas show cuboidal to columnar phenotypes, an outlook similar to the papillary carcinoma of the thyroid In such case, IHC, in ... cytological examination and clinical staging, FDG PET/ CT (GE Discovery ST ,USA) was performed, which showed the increased FDG uptake of the tumor in terms of the SUVmax in 3.69 and the delay SUV in 5.17...

Ngày tải lên: 09/08/2014, 02:21

... improvement in both anatomic localization and diagnostic accuracy [10-12] Since the introduction of the FDG- PET/ CT, the vast majority of systems are now produced as combined FDG- PET/ CT rather than FDGPET ... evaluation of CT characteristics of the thyroid lesions detected on the FDG- PET/ CT Choi et al [1] reported improved accuracy for characterizing thyroid nodules on the FDG- PET/ CT using CT attenuation ... administration of 550 MBq of F-18 FDG Whole body emission Figure Focal FDG uptake on PET/ CT Focal FDG uptake on PET/ CT 54 year old female with breast cancer The 18F- FDG PET/ CT revealed focal uptake with...

Ngày tải lên: 09/08/2014, 04:21

... management Figure imaging PET- CT1 Maximum intensity projection (MIP) of the whole body FDG Maximum intensity projection (MIP) of the whole body FDG PET- CT imaging There is intense uptake in the prostate ... detection of malignant disease In addition, routine whole body imaging make it best imaging modality for staging and restaging of most of the malignant diseases In prostate adenocarcinoma, FDG- PET ... of FDG- PET application in neuroendocrine tumor of the prostate and metastatic disease In some selected cases of neuroendocrine tumor of the prostate, whole body FDG- PET may be helpful for detection...

Ngày tải lên: 09/08/2014, 07:21

... rates without increased normal tissue complication rates Though molecular imaging with choline PET/ CT is promising, careful interpretation of PET/ CT findings and consideration of clinical data ... choline -PET in androgen-deprived patients [13] and inflammatory tissue changes resulting in an increased uptake of choline imitating cancer growth [14] Conclusions F18-fluoroethylcholine -PET/ CT ... stage: initial tumor stage; iPSA: initial PSA value (ng/ml); PSA nadir: minimal PSA value after prostatectomy (ng/ml); dt PSA: PSA doubling in months; PET/ CT: FEC -PET/ CT result (P: FEC uptake in...

Ngày tải lên: 09/08/2014, 09:20

... Adenocarcinoma Adenocarcinoma Adenocarcinoma Adenocarcinoma Adenocarcinoma Adenocarcinoma Adenocarcinoma Adenocarcinoma Adenocarcinoma Adenocarcinoma Adenocarcinoma Adenocarcinoma Adenocarcinoma ... MBq 1 8FDG intravenous injections PET images were obtained one hour after injection The PET images were obtained at each bed position for minutes with 6–8 beds to cover the entire body The PET ... dedicated contrast CT, F-18 FDG PETCT and post-treatment PET- CT were included Baseline pre-radiotherapy PET- CT was performed before any treatment, followed by post-radiotherapy PET- CT at a median...

Ngày tải lên: 09/08/2014, 10:21

... reflecting the actual specificity of PET in the characterizing of pulmonary nodules The introduction of dedicated PET/ CT scanners to the clinical arena in early 2001 [14], has resulted in improved ... from the informed consent requirement Imaging protocol of 18F- FDG PET scans All patients fasted at least hours before receiving a 10– 15 mCi (370 MBq-555 MBq) dose of intravenous 18FFDG PET scans ... improved accuracy in the characterization of pulmonary nodules [13], by maintaining the synergism between the anatomic sensitivity of CT, and metabolic specificity of PET Although, FDG- PET/ CT is a valuable...

Ngày tải lên: 10/08/2014, 22:20

... Während eine CT meist in Inspirationsstellung in Sekunden akquiriert wird, dauert die PET Minuten, in denen der Patient zwar flach, aber kontinuierlich atmet Das Resultat ist eine PET- Aufnahme in Atemmittellage ... aus der PET- Bildgebung abgeleitet wird 2.3 FDG PET/ CT Die PET/ CT- Aufnahmen wurden in beiden Kliniken mit dem gleichen Biograph PET/ CT (Siemens, Medical Solution Inc., Hoffman Estates, Illinois, ... Funktionsweise von Positronenemissionstomografie (PET) und Computertomografie (CT) Während im PET die beiden, in einem Winkel von 180° abgestrahlten Teilchen in einem ringförmigen Detektor registriert und...

Ngày tải lên: 26/11/2015, 10:18

... Hibernating myocardium Infarcted myocardium 1/15/2016 TỔNG QUAN Stunned myocardium Hibernating myocardium DSE, Nuclear Medicine, MRI Infarcted myocardium TỔNG QUAN Nguyên lý tạo ảnh FDG PET Journal ... Diagnostic Imaging in Therapy 2015; 2(1): 30-102 1/15/2016 TỔNG QUAN TÌNH TRẠNG CƠ TIM SỐNG ĐẶC TRƯNG BỞI Tổn thương tưới máu không hồi phục 99m Tc MIBI Duy trì chuyển hóa tim FDG PET Missmatch ... cộng (2002), J Am Coll Cardiol 39(7), tr 1151-8 1/15/2016 ĐẶT VẤN ĐỀ Kỹ thuật chụp PET sử dụng  Đánh  18F- FDG cho phép: giá khả sống tim Phân biệt tình trạng tim đông miên khả hồi phục với...

Ngày tải lên: 15/01/2016, 09:00

... receiving an intravenous injection of 440 MBq of 18F- FDG Scanning began 60 minutes later A combined PET/ CT in- line system (Biograph LSD, Siemens, Knoxville, TN) was used for all data collection CT ... scanning accompanied by FDG uptake were started on induction chemotherapy without operation Previous studies reported that FDG- PET, and not PET/ CT, was more sensitive than CT scanning for detecting ... patients Nine patients who had metastatic lesions or nonresectable primary tumors in either PET/ CT or conventional CT scan were not operated on The PET/ CT findings of these patients are listed in Table...

Ngày tải lên: 09/08/2014, 03:22

... squamous cell carcinoma in 20 cases, cloacogenic carcinoma in 3, adenocarcinoma in 2, and basal cell carcinoma in Tumor was confined in the anal canal in 10 cases, extended to the lower rectum in cases, ... gastro-intestinal tract tumors In particular, the GTV was drawn manually on CT and semi-automatically on PET images For delineating the PET/ CT- GTV and the PET/ CT- CTV, the operator considered both CT and PET ... PET information outlining the volume identified by one or by both imaging modalities The CTV was drawn manually on CT and on PET/ CT images taking into account respectively the CT- GTV and PET/ CT- GTV...

Ngày tải lên: 09/08/2014, 08:22

... radiosynthesis of [18F] FE-DTBZ-d4 and the measured in vitro binding potential [BP] in the pancreas To test our hypotheses of reduction in defluorination and uptake in the bone while maintaining a similar ... functions (Equation 1) which we can express in a vector form; the input function [Cinput], the transfer function [HTR], and the output function [Ctissue] were defined as follows: Cin ⊗ H TR = Ctissue ... aspects of dementia [1] and Parkinson's disease [2] in the clinic High VMAT2 expression has also been found in insulin-producing beta cells in the endocrine islets of Langerhans, but not in the...

Ngày tải lên: 20/06/2014, 21:20

... in nu/nu 537−MEL in nu/nu H2122 in nu/nu FaDu in C.B−17 scid H292 in C.B−17 scid BT474M1 in beige−scid nude HCT116 in nu/nu HCT116 in nu/nu A2058 in nu/nu A375 in nu/nu A2058 in nu/nu A2058 in ... cell line/mouse strain A B C D E F G H I J K BT474MI in beige-scid nude HCT116 in athymic nude PC3 in athymic nude FaDu in C.B.-17 scid H292 in C.B.-17 scid H596 in huHGF transgenics 537-MEL in ... ([glucose] / 100 mg/dL) In the clinical trial setting, even modest reductions in variability can translate to tangible savings in money, time, and patient enrollment Competing interests The authors...

Ngày tải lên: 21/06/2014, 17:20

... well-differentiated non functioning pancreatic endocrine carcinoma, functioning bilateral adrenocortical carcinomas were diagnosed A not previously described, novel germline mutation (p.E45V) in exon of MEN1 ... Menin-JunD interaction involves the N-terminus (amino acids 1-40) and midregion (amino acids 323-428) of Menin and requires the N-terminus of JunD (amino acids 8-70) Menin’s tumor suppressor involves ... excessive amounts of hormones such as gastrin, insulin, glucagon, somatostatin, neurotensin or vasoactive intestinal polypeptide and are associated with distinct clinical syndromes [2] Pancreatic tumours...

Ngày tải lên: 09/08/2014, 01:24

... carcinoma [21] Furthermore, they showed PET -FDG imaging modified the management of 13.7% of patients Our findings indicate that PET- CT changed the stage in a large number of patients: upstaging ... that adding PET- FDG or PET/ CT -FDG to standard work-up led to a higher staging accuracy with higher specificity [18-21] A recent study examining this issue was conducted by Lonneaux et al in a prospective, ... criteria defined above were considered “positive” All scans were PET- CT fusion studies and were obtained on a single scanner at MBPCC in the majority of cases (47/53) PET- CT scans were obtained in standard...

Ngày tải lên: 09/08/2014, 03:22

... more clinical studies are required to better define the role of PET- CT fusion in this setting Competing interests We have no personal or financial conflict of interest and have not entered into ... Volumes by CT and PET- CT in 13 Patients with Malignant Pleural Mesothelioma Volume, cc GTV Mean ± S.D Min-max CTV Mean ± S.D Min-max PTV1 Mean ± S.D Min-max PTV2 Mean ± S.D Min-max CT PET- CT P Value ... with CT- and PET- CT based GTV delineations; (a) axial CT (b) axial PETCT, (c) coronal CT, (d) coronal PET- CT *Abbreviations: GTV = gross tumor volume; CT = computed tomography; PETCT = positron...

Ngày tải lên: 09/08/2014, 10:20

... clinical outcome analysis of PET/ CT in combination with IMRT has not been reported so far, although broad interest exists for structured integration in clinical routine [31,32] Both IMRT and integrated ... tracer, 18F- fluorodeoxyglucose (1 8FDG) , acts as a glucose analogue allowing imaging of glucose metabolism, a process that is known to be enhanced in many malignant tumours [11] Combining PET and CT ... difficulties in the interpretation of PET images without anatomical registration Wong et al have shown that CT or MR -PET -FDG images provide more clinically relevant information than obtained from clinical...

Ngày tải lên: 09/08/2014, 10:21

... gastrointestinal tract Most GISTs are caused by mutations in the KIT and PDGFRA receptors, leading to upregulated tyrosine kinase activity [1,2] Tyrosine kinase inhibitors (TKIs), imatinib and ... synergic effects on multiple targets [29] A clinical study reported that nilotinib alone or in combination with imatinib was well tolerated overall and showed clinical activity in 53 imatinib-resistant ... combination of nilotinib with mTOR inhibitors To date, no one combination of agents has yet been approved as standard GIST treatment in clinical practice However, there is a growing interest in...

Ngày tải lên: 10/08/2014, 10:20