17 39 reduce safety stocks by accelerating the flow of internal information

... Schmidheiny Markus Akermann The term of office for all members of the Board of Directors expires on the day of the 2002 General Meeting of Shareholders The Area Managers and the CEO of “Holderbank” Management ... consolidat- further enhanced by the takeover of cement ed in the second half of 1998, merged with terminals on several islands of the eastern Juan Minetti at the beginning of 1999 Caribbean The five ... capable of loading 1,200 tonnes in The local winegrowers’ cooperative is justifi- just 75 minutes; on the other, there is the ably proud of its harvest: their quality has natural environment of vineyards...

Ngày tải lên: 27/07/2014, 16:07

Ngày tải lên: 21/09/2013, 05:29

... “be Undone, / By the departure of a star, / while they enjoy the Sun” (Meserole ) The living God who had authored the sanctity of the dead was poised to fill the space created by their leaving ... reaction to the vision of the valley of dry bones, the divine question and the human answer describe the Puritan response to the challenge of writing resurrections for the dry bones of the holy ... these poems indeed prepared readers to take the place of the deceased, this would occur only if the spirit of the dead infused the living Only through the survivor’s genuine assimilation of the...

Ngày tải lên: 01/11/2013, 10:20

... VoP is growing, there is still considerable debate about whether the underlying network technology will be ATM or IP At the edge of the network the choice, driven primarily by the regional Bell ... resources are reserved all the way from sender to receiver before the start of the transfer, thereby creating a circuit The resources are dedicated to the circuit during the whole transfer Control ... than the architecture of today's circuit switches There is significant debate in the industry about the definition of a softswitch, its role within the network, how it should interface with other...

Ngày tải lên: 10/12/2013, 17:15

... the context of the time they were made ED 0414 Internal audit case study: is co-sourcing the right move? Four leaders of fictional XYZ Technology Group consider co-sourcing as part of their internal ... help to frame facilitated workshops and drive the scope of internal audit reviews Q: Which of the following you consider to be the key elements of the internal audit risk assessment process? Select ... to other parts of the company Three of my positions are rotations, with the stated purpose of staying for two years, gaining the experience of working in an audit department and learning how they...

Ngày tải lên: 15/03/2014, 23:20

... Mutation of the octamer in the iNOS and G-CSF promoters results in a reduction of more than 90% in the LPS-induced promoter activities of these genes [13,30], suggesting the essential role of the ... attributed to the decrease in Oct-2 expression caused by these reagents The involvement of Oct-2 in iNOS and G-CSF expression was further supported by the finding that knockdown of Oct-2 expression ... concentration of G-CSF protein in the medium was measured by ELISA (B) The values for the LPS-treated cells were divided by those for the non-LPS-treated cells and are shown as a percentage of the values...

Ngày tải lên: 22/03/2014, 17:20

... (n) The lower plots show the difference of the coefficients in the presence of (B) DGP or (C) MG relative to water The points on the horizontal axis cover the entire sequence of residues of the ... for some of these residues (Fig 3) In particular, the exposure of the residues that comprise the lower part (relative to the orientation depicted in Fig 2) of the hydrophobic core of the native ... series of mutants of RdDg was constructed to investigate the importance of these mutations on the degree of stabilization rendered by solutes It is well-documented that the thermal denaturation of...

Ngày tải lên: 30/03/2014, 15:20

... trạng chấp nhận khai thác tài nguyên tác động đến môi trường, phương thức tăng trưởng theo lối quảng canh theo diện rộng mà không đầu tư chất xám mức Do đó, chuyển biến bước phát triển vào bế ... Tạp chí Tài Doanh nghiệp, số 11 - 2003, Tr 17 - 19 [7] Võ Xuân Tiến, Toàn cầu hoá kinh tế vấn đề đặt ra, Tạp chí Sinh hoạt Lý luận, số - 2004, Tr 35 - 39 [8] Đổ Trọng Thịnh, Hội nhập Tổ chức Thương ... đổi ngoại thương nhiều, công ty, người tiêu dùng quốc gia thu nhiều lợi ích nhờ vào lợi kinh tế theo quy mô, học hỏi thông qua kinh nghiệm thực tế khả phân chia chi phí nghiên cứu nhiều đơn vị...

Ngày tải lên: 08/04/2014, 21:50

... to the standards of animal care as outlined in the Guide for the Care and Use of Experimental Animals of the Medical College of Shanghai Jiaotong University The study protocol was approved by the ... counting the cells that migrated to the lower side of the filter with optical microscopy at 400× A total of five visual fields at the center and in the surrounding areas were counted, and the average ... efficiency of the target gene after RNAi The cell line with stable transfection and effective inhibition of the ADAM 10 gene was named SACC-ADAM 10-RNAi, and the cell line with stable transfection of the...

Ngày tải lên: 18/06/2014, 16:20

... half of the signals was used to train the parameters of the classifiers; their performance was then assessed on the second half of the data The performance of the classifiers was measured by comparing ... the value that occurs most as a corresponding estimation Thus, the value of the final output is the class with the greatest number of occurrences in this point window of the decision stream The ... values for the different parameters of the classification algorithm, the ability of discriminating the different stimuli was investigated In particular, the median and the maximum of the classification...

Ngày tải lên: 19/06/2014, 08:20

... experiments, analyzed the data, generated the figures, and wrote the manuscript JW did parts of the animal surgery JW, YS, LW, EB performed the experiments PEK provided advice in the design of the study ... (MCAO) was produced by filament occlusion of the right MCA following a modification of the method reported by Clark and colleagues [21] In brief, mice were anesthetized with isoflurane (induction ... regulator of macrophage activation [15] Further investigations by our group and others indicated that MCPIP1 can play a significant antiinflammatory role by inhibiting the generation of a set of major...

Ngày tải lên: 19/06/2014, 22:20

... however the role of genistein in chemo-resistant ovarian cancer cells has not been investigated Therefore, the intent of this study was to evaluate the effect of genistein for sensitization of ovarian ... sensitize even the drug-resistant cell line and cause inhibition of cell viability Further, to assess whether the loss of overall cell viability could also be due to the induction of apoptotic ... on the DNA binding activity of NF-κB Genistein inhibits NF-κB DNA binding activity Specifically, the effects of pretreatment followed by the combination treatment were studied in the context of...

Ngày tải lên: 20/06/2014, 07:20

... output The induction of apoptosis of the endocardium and erythrocytes by b-lapachone is mediated through an NQO1- and calcium-dependent pathway This study further demonstrated the importance of the ... [38 ,39] Since we observed a decreased number of erythrocytes in b-lapachone-treated embryos, we then evaluated the effect of b-lapachone treatment on the wall shear stress in the caudal artery of ... artery of DMSO- and b-lapachonetreated embryos by tracing the distance they traveled in a fixed period of time via time-lapse fluorescence microscopy Flow rate (Q) was then calculated based on the...

Ngày tải lên: 10/08/2014, 10:20

... associated with the expression of pro-inflammatory cytokines To determine whether the inhibition of IL-6 and IL-8 expression was mediated by inhibition of MAPK, we examined the effect of POMx on the activation ... reduced the PMA plus A23187-induced luciferase activity (Fig 4C) To further strengthen the relation of NF-κB pathway and the expression of IL-6 and IL-8 in KU812 cells, we next investigated the ... μg/ml of POMx significantly decreased the PMACI-induced IL-6 and IL-8 production in the culture supernatant of activated KU812 cells Effect of POMx on the activation of MAPK Activation of MAPKs...

Ngày tải lên: 11/08/2014, 08:22

... patterns of genes of the ethylene biosynthesis and GUS activity in the ACS2:GUS line closely matched the unfertilised ovule senescence [4] In view of the fact that the up-regulation of those genes of ... degradation of all tissues in the ovule Despite all this evidence, the independence of the pistil responsiveness to GA of the ovule fate cannot be completely ruled out Elucidation of the location of the ... that the role of ethylene in accelerating the onset of ovule senescence without affecting the progression pattern Discussion The experiments described in this article unveil the role of the hormone...

Ngày tải lên: 11/08/2014, 11:20

... sequences of known miRNAs of other species [31-34] Out of the 84 unique miRNA sequences, 49 can be confirmed by our sequencing Table Summary of small RNA sequencing No of reads No of unique No of unique ... zma-miR390 zma-miR390a 49.53 7.43 8.1 0.94 zma-miR393 zma-miR393a, c - - - - zma-miR393b - - - - zma-miR394 zma-miR394a, b 23.59 2.84 4.12 - zma-miR395 zma-miR395a, b.d, e, f, g, h, I, n, zma-miR395k ... zma-miR396 zma-miR397 zma-miR398 zma-miR399 0.73 0 .17 - - - 0.08 - - zma-miR399d - 0.08 - - zma-miR399e, j, i 0.59 - 0.07 - zma-miR399f - - 0.07 - zma-miR399g zma-miR408 zma-miR482 zma-miR399a,...

Ngày tải lên: 11/08/2014, 11:21

... Guidelines for the diagnosis and treatment of pulmonary hypertension: The Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European ... 0.01) In accordance with the results of p27kip1, there was no significant change of the Skp-2 relative level between the normoxia group and the normoxia+b-E2 (Figure 3a) To further confirm if p27kip1 ... in the process of chronic hypoxia-induced pulmonary artery remodeling, the lysates of each group of PASMCs were used to WB assays As the results showed, compared with the normoxia group, the...

Ngày tải lên: 12/08/2014, 13:22

... with the reduced production of infectious virions, thereby reducing the overall infectivity of the virus In support of this hypothesis, we found that the compensatory mutations did not rescue the ... base-pairing of the DIS of two RNA molecules is a major determinant in the selection of the copackaged RNA partners, and the identity of the DIS plays an important role in the copackaging of RNAs ... infectious titer of the virus, normalized against the amount of p24, to quantify the production of infectious virus by the mutants NLΔSL1 produced 20-fold fewer infectious viral particles than the wild-type...

Ngày tải lên: 13/08/2014, 01:20

... Once the machine utilization rate and job tardiness are displayed on the screen, the user may request the system to improve the schedule by the following two ways: (1) Reduce the total number of ... operation of Job‘j’ 33 Chapter The Facilitator for Integration StartT(j, k) – The starting time of the ‘k’th operation of Job‘j’ EndT(j, k-1) – The ending time of the ‘k-1’th operation of Job‘j’ ... reverse the order of the two sequential operations on a machine; reverse the order of the two sequential operations within a job; change the method used to perform an operation With SA, the trade-off...

Ngày tải lên: 08/11/2015, 16:30

... that the tool offers two feedback mechanisms: one at the time the auestion is beinq annotated and the other as the interview ends, At the 86 Proceedings of the 8th International Workshop on Software ... entities with information already available for other entity defined and the arcs the relationships among the information The nodes serve as basis for the questions posed by the assistant The arcs ... ‘in by one of the questions from the automation strategy, the control mechanism activates the production memory to check if a rule will fire given the state of the knowledge base These types of...

Ngày tải lên: 15/01/2016, 16:29