16 binding to the default container for computers
Tài liệu Báo cáo khoa học: Evidence for noncooperative metal binding to the a domain of human metallothionein ppt
... leading to formation of the M4a cluster prior to formation of the M3b cluster, demonstrating that the individual binding constants of divalent metal ions for the a domain are larger than those for the ... two metal ions to the a domain in independent tetrathiolate sites, the choice for the third incoming metal ion would be to form a bridging interaction in the a domain or to form another independent ... domain in efforts to elucidate the potentially cooperative nature of the metal -binding reaction within each of the domains Thus, the goal is to elucidate the metallation mechanisms of the individual...
- 9
- 533
- 0
Báo cáo khoa học: Copper-containing nitrite reductase fromPseudomonas chlororaphis DSM 50135 Evidence for modulation of the rate of intramolecular electron transfer through nitrite binding to the type 2 copper center pot
... studies seem to indicate that cytochrome c551 could be the physiological electron donor to the aforementioned Nir [11] The electrons donated by the donor to the T1Cu center are transferred to the catalytic ... that the deviation of the Sd(Met150) atom from the axial position of the NNS plane formed by two Nd(His95 and His145) atoms and one Sb(Cys136) atom causes the different colors in the enzymes The ... from the Asp98 residue to the oxygen atom of the substrate, yielding an OẳNOH intermediate The NO bond in this oxygen atom is then broken, yielding the product NO, whose release re-establishes the...
- 9
- 393
- 0
Báo cáo y học: " Incorporation of podoplanin into HIV released from HEK-293T cells, but not PBMC, is required for efficient binding to the attachment factor CLEC-2" ppsx
... due to the interaction of the virion-incorporated factors with their cognate receptors on HIV target cells, as exemplified by the up to 100-fold increased infectivity of ICAM-1-bearing viruses for ... prominent example for such a factor is ICAM-1 which was found to be incorporated into the viral membrane, and to facilitate HIV-1 infection by binding to its ligand LFA-1 on T-cells [12] The potential ... decreased binding of CLEC-2 to rhodocytin in surface plasmon resonance binding studies [34] We addressed if these residues were also required for binding to soluble podoplanin Flow cytometric...
- 18
- 294
- 0
Tài liệu Báo cáo khoa học: Characterization of ICAM-4 binding to the I domains of the CD11a/CD18 and CD11b/CD18 leukocyte integrins pptx
... GST fusion protein for binding to the captured ICAM-4Fc strengthens the earlier results that the binding sites for the CD11a and CD11b I domains in ICAM-4 are different although they could be partially ... being a ligand binding area for a red cell receptor However, it is probable that other erythrocyte receptors for the CD11a and CD11b I domains exist because of the residual binding of the ICAM-4 ... to 60% in the presence of the corresponding I domain compared to 20% for the interaction between ICAM-4 and CD11a/CD18 This indicates differences in binding of ICAM-4 to these two integrins The...
- 14
- 495
- 0
Báo cáo khoa học: ` Inhibition of human ether a go-go potassium channels by 2+ Ca ⁄calmodulin binding to the cytosolic N- and C-termini potx
... promoting binding to the target (e.g [13,16,17]) Binding to the target can increase the Ca2+ -binding affinity to CaM further [17,18] In addition, subsequent binding of Ca2+ to the N-lobe then induces ... respect to the binding to synthetic TMR-labeled peptides (see Fig 3A–C) coding for the putative binding sites in hEAG1 In the presence of 25 lm free Ca2+, the aspartateto-alanine mutations in the ... of the CaM constructs bound to the peptide in the absence of Ca2+ For the TMR-labeled peptide C2, EF-hand mutations and increased the KD by about a factor of seven (to 1560 ± 190 nm compared to...
- 13
- 500
- 0
Báo cáo khoa học: Two conserved domains in regulatory B subunits mediate binding to the A subunit of protein phosphatase 2A pdf
... [10,21] To optimize conditions for the assay, fulllength B56a was ®rst tested for binding to GST-A B56a full-length protein bound well to GST-A, but not to GST alone (Fig 1A) To further con®rm the ... present in the reticulocyte lysate may contribute to the formation of heterotrimers [27] To map the region(s) of B56a responsible for binding to the A subunit, multiple B56 fragments were generated ... independently binding to GST-A (Fig 2) These regions were named A subunit binding domains (ASBD) and Given that the two distinct regions can bind to the structural A subunit, an effort was undertaken to...
- 7
- 550
- 0
Báo cáo khoa học: pyr RNA binding to the Bacillus caldolyticus PyrR attenuation protein – characterization and regulation by uridine and guanosine nucleotides potx
... binding for all three binding loops, RNA binding to PyrR PyrR binding to BcBL1 resembled the binding observed for the other two binding loops The apparent dissociation constant (Kd) values for RNA binding ... demonstrating the antagonism of the two effectors When the ratio of GTP to UTP was varied over the same range, the effects were similar to the effects of GMP and UMP; the values for the apparent Kd for ... 162 binding of PyrR to BcBL2 RNA with the total concentration of the two effectors held constant When the GMP to UMP ratio was increased from 0.11 to 19, the apparent dissociation constant for...
- 16
- 309
- 0
A BOATER’S GUIDE TO THE FEDERAL REQUIREMENTS FOR RECREATIONAL BOATS AND SAFETY TIPS potx
... Seatanypassengerson the bottomof the boat,near the center line • If the enginefails,trailaseaanchorfrom the bowof the boat to keepitheadedinto the waves (Abucketcanworkasasea the operator’ssideof the boat,alwaysinview ... waterplus the distancefrom the surfaceof the water to where the “footprint”in the waterwhenloaded to itsratedcapacity;catamarans, anchorwillattach to the bow For example,if the wateriseight ... actionwhenpeoplearein the waternearyourboatis to shut off your engines Weather Youshouldneverleave the dockwithoutfirstchecking the local weatherforecast Youcanget the weatherinformationfrom the TV,...
- 45
- 515
- 0
Báo cáo khoa học: Heavy metal ions inhibit molybdoenzyme activity by binding to the dithiolene moiety of molybdopterin in Escherichia coli pdf
... strictly required for the biosynthesis of Moco in bacteria [22] In addition to copper, various metals are known to bind tightly to sulfur-rich sites, leading to the question of whether other metal ions ... MGD formation is catalysed by MobA only after the coordination of a molybdenum atom to the dithiolene moiety of MPT [19] To determine whether molybdate can be replaced by other metals for the ... activity of the MoeA protein Although the synthesis of the dioxo Moco found in hSO seems to be more susceptible to nonspecific metal insertion, the biosynthesis of the bisMGD cofactor present...
- 12
- 399
- 0
Báo cáo khoa học: Transcriptional activity and Sp 1⁄3 transcription factor binding to the P1 promoter sequences of the human AbH-J-J locus docx
... boxes similar to the Sp1 consensus binding sequence (Fig 5A) The location of these putative Sp1 -binding sites within the P1 promoter sequence is shown in Fig 5A,B, together with the transcription ... extract to these boxes Binding of nuclear factors to GC-rich boxes of the AbH-J-J P1 promoter In order to study protein–DNA interactions and further characterize the transcription factors involved, ... transcription factors There is strong evidence demonstrating that transcription factors belonging to the Sp1 family interact with other transcription factors, including some proteins binding to the P2...
- 15
- 362
- 0
Báo cáo khoa học: Heme binding to the second, lower-affinity site of the global iron regulator Irr from Rhizobium leguminosarum promotes oligomerization potx
... very similar to that of the wild-type protein, and the addition of heme to the mutant polypeptide caused a similar shift in equilibrium towards the larger (hexameric) species Therefore, the process ... concentrations, to a single component model gave a mass of 96.6 ± kDa for the heme-bound IrrRl sample (residuals for the fits are shown in the inset to Fig 3C) The data thus indicate that the higher ... remained in the ferrous state in the reference cuvette, thereby imparting a different form on the difference spectrum form Therefore, it is clear that IrrRl does not contain a ferrous heme-binding...
- 11
- 281
- 0
Báo cáo hóa học: " Research Article RRES: A Novel Approach to the Partitioning Problem for a Typical Subset of System Graphs" potx
... graphs in the field to have rather low values for rloc and a low to medium value for γ, while having low values for ρ The metric κ has been calculated for all the sample graphs, and the performance ... on the x-axis, the performance of the RRES algorithm is plotted The dotted lines show the ES performance For a window length of 20, the obtained values for RRES and ES naturally coincide The ... Ttotal − Tmin RA = Alimit , Atotal RS = Slimit Stotal (8) The totalised values for area Atotal , code size Stotal , and execution time Ttotal are simply built by the sum of the maximum gate counts...
- 13
- 310
- 0
Báo cáo toán học: "The inverse problem associated to the Davenport constant for C2 ⊕ C2 ⊕ C2n, and applications to the arithmetical characterization of class groups" doc
... each of these has a positive effect on the estimates for the height We refer to [22, Theorem 7.1] for a result of this form for Cm and to [51] for an application of it in this context, and to [26, ... [11] for a generalization) On the other hand, this formula is useful to decide which choice for the subgroup H is ‘suitable’ and to highlight limitations of this form—strictly limiting to the ... investigations on the inverse problem is twofold On the one hand, we obtain a full solution to the inverse problem for groups of the form C2 ⊕ C2n for each n ∈ N The motivation for and relevance of these...
- 42
- 350
- 0
Báo cáo y học: " Effectiveness of an intercultural module added to the treatment guidelines for Moroccan and Turkish patients with depressive and anxiety disorders" ppt
... appointment for an intake Page of interview by a therapist from the matching condition After this intake interview the patients receive study information and the informed consent form from the therapists ... random number generator The patients are randomly assigned for either intake or treatment to therapists who are trained in cultural competence (the intervention group) or to therapists who are ... control-group therapists In both clinics six therapists are selected for the intervention group and six for the control group of this study In both groups disciplines of the therapists, the average...
- 7
- 350
- 0
APPLICATIONS OF THE ALEXANDER IDEALS TO THE ISOMORPHISM PROBLEM FOR FAMILIES OF GROUPS
... all the groups in that family are distinct Acknowledgments The authors would like to express their gratitude to the Vietnam Institute for Advanced Study in Mathematics for support during the ... APPLICATIONS OF THE ALEXANDER IDEALS TO THE ISOMORPHISM PROBLEM The Alexander ideals not depend on the choices of the CW-complex X and the presentation (1) However we have a freedom in choosing the isomorphism ... We use the fact that B(m, n) ∼ = B(−m, −n) to reduce the computation to the subcase c) So I = (−m + nt1 ) = (m − nt1 ) 6 DO VIET HUNG AND VU THE KHOI Theorem 2.2 (Moldavanskii [14]) The group...
- 10
- 271
- 0
Báo cáo khoa học: Nucleotide binding to human UMP-CMP kinase using fluorescent derivatives ) a screening based on affinity for the UMP-CMP binding site potx
... probes to monitor the binding of nucleotides to UCK These assays were used to determine the binding afnity of bisubstrates and new phosphonate analogs and to validate a uorescent approach for high-throughput ... experiments to determine the binding of natural substrates to the donor and the acceptor sites of human UCK The ATP -binding site (donor -binding site) of human UCK was probed with the uorescent ... indicating that their binding to the NMP -binding site is unproductive UCK has been identied in human liver as the enzyme that catalyzes the rst phosphorylation step for cidofovir [6] The binding of...
- 11
- 468
- 0
Báo cáo khoa học: Structural framework of the GABARAP–calreticulin interface – implications for substrate binding to endoplasmic reticulum chaperones potx
... the ER lumen [17] However, the protein is in fact not restricted to the ER, but does exert important functions in other cellular compartments, such as the cytosol [29], the nucleus [30] and the ... is given in the bottom panels of Fig for the two hydrophobic pockets Binding of Trp183 (dark blue) in hp1 induces a slight shift of helix a2 (blue), similar to the effect of Trp11 in the K1 peptide ... red) Notably, the two complexes differ in both the position and conformation of these tryptophan side chains Specifically, Trp183 extends deeper into the pocket, and this is reflected by the side chain...
- 13
- 190
- 0
báo cáo hóa học:" Research Article Planning of Efficient Wireless Access with IEEE 802.16 for Connecting Home Network to the Internet" potx
... 60 is used to determine the cell range of AP The formulas are necessary to calculate the values in the link budget which use basic mathematical functions and are very straightforward to implement ... driven by the need for NLOS operation Because residential applications are expected, rooftops may be too low for a clear sight line to an AP antenna, possibly due to obstruction by trees Therefore, ... and so forth The propagation of radio frequency depends on the physical environment, therefore, we have to define the service area and select appropriate radio propagation model to predict the path...
- 12
- 367
- 0
Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25