Ngày tải lên: 01/06/2014, 19:42
... disputable relevance of our results to pathogenesis and clinical manifestations of atherosclerosis. The finding of C. pneumoniae in serum of ACS patients does not establish causality for the pathogen ... from the same volume of whole serum with QIAmp Blood Midi Kit (QIAGEN, Valencia, CA) according to the manual. Bacterial DNA was also extracted from the bac- terial particles trapped from the ... may originate from destructed mononuclear cells and/or macrophages residing in the atherosclerotic plaques. However regardless of the origin, we can claim that the presence of virulent chlamydial...
Ngày tải lên: 26/10/2012, 08:57
Tài liệu THE ESTIMATION OF THE EFFECTIVE REPRODUCTIVE NUMBER FROM DISEASE OUTBREAK DATA pdf
... final part of the outbreak data, as there is often a period lasting ten or more weeks when there are few cases. We investigated whether the removal of the lowest-valued points from the data sets ... differences between the behavior of the SIR model and the data. Potential sources of these differences include inadequacies of the mathematical model to de- scribe the process underlying the data and ... proportional to the square of the predicted incidence: w j = 1/[z(t j ; θ)] 2 . On the other hand, if ρ = 1/2, then the weights are proportional to the rec iprocal of the predicted incidence; these correspond...
Ngày tải lên: 13/02/2014, 16:20
Tài liệu Banks’ exposure to interest rate risk, their earnings from term transformation, and the dynamics of the term structure pptx
... is the cross-sectional average of the bank-specific variable α i of those banks for which there is an observation in month t. As the composition of this sample changes in the course of time, the ... (column 3) and the model with only the regulation variables (column 4). The R 2 of the full model is 17.24%, i.e. the combined contribution of the systematic factor and the regulation to the total ... constant and the own funds decrease or increase. With the help of the two other specifications, it is possible to disentangle the contri- butions of the systematic factor and of the regulation....
Ngày tải lên: 16/02/2014, 06:20
Tài liệu ANDRE BAZIN FROM WHAT IS CINEMA? THE ONTOLOGY OF THE PHOTOGRAPHIC IMAGE pptx
... applying the optical principle of the persistence of the image on the retina, as also the continuous progress of the syntheses of movement as compared with the state of photographic techniques. The fact ... to have the last word in the ar- gument with death by means of the form that endures. If the history of the plastic arts is less a matter of their aesthetic than of their psychology then it will ... of all is the obstinate resistance of matter to ideas rather than of any help offered by techniques to the imagination of the researchers. Furthermore, the cinema owes virtually nothing to the...
Ngày tải lên: 19/02/2014, 10:20
Tài liệu Báo cáo khoa học: Crystal structure of thiamindiphosphate-dependent indolepyruvate decarboxylase from Enterobacter cloacae, an enzyme involved in the biosynthesis of the plant hormone indole-3-acetic acid doc
... catalytic residues The active site cavity in IPDC extends from the thiazolium ring of the cofactor to the surface of the protein. The entrance of the active site cleft is covered by the C-terminal helix ... on the other hand involving the C-terminal part of the polypeptide chain (Fig. 7). In the latter, differences in the conformation of the loop between Fig. 6. Stereo picture of the model of the a-carbanion/enamine ... However, the packing of the two dimers in the tetramer is different from that of the PDCs of known structure, best described as a 20° rotation of one dimer towards the other when compared to the Z....
Ngày tải lên: 20/02/2014, 11:20
Tài liệu Báo cáo khoa học: Purification and characterization of a sialic acid specific lectin from the hemolymph of the freshwater crab Paratelphusa jacquemontii pdf
... NeuAc. Discussion The presence of naturally occurring agglutinins in the hemolymph of several crustaceans has been well known since the beginning of the 20th century [34]. An evaluation of the literature ... °C. The eluant was collected at a rate of 0.6 mLÆmin )1 .Thecolumnwas washed with HSB until the A 280 of the effluent was < 0.002. The column was further washed with LSB at 4 °C until the A 280 of ... containing 100 lLof100m M CaCl 2 at a rate of 0.3 mLÆmin )1 . The presence of calcium chloride was required in the collected fractions because the lectin was unstable in the presence of EDTA. The fractions...
Ngày tải lên: 21/02/2014, 00:20
Tài liệu Báo cáo Y học: Identification of a set of genes involved in the biosynthesis of the aminonucleoside moiety of antibiotic A201A from Streptomyces capreolus pdf
... proteins implicated in the biosynthesis of the aminonucleoside moiety of A201A. Here we report the sequencing of a total of 6946 bp, which include the ata genes most likely implicated in the biosynthesis of this ... it. Further sequencing of the ata cluster could provide an insight into the biosynthetic pathway of the other moieties of A201A and provide probes which may be useful to identify genes of the hygromycin ... in the biosynthesis of the D -rhamnose and a-p-coumaric acid moieties of A201A. Further sequencing of 2 kb of DNA downstream of ard1 has disclosed a region which might contain one end of the...
Ngày tải lên: 21/02/2014, 01:21
Tài liệu Báo cáo khoa học: The structure of the carbohydrate backbone of the lipopolysaccharide from Acinetobacter baumannii strain ATCC 19606 docx
... 269) 427 [26,27]. Then, the biosynthesis of the core region of LPS from A. baumannii strain ATCC 19606 should proceed with the introduction of a third Kdo residue to O-5 of the second Kdo. This ... mechanism of the transfer of the third Kdo residue has not yet been identi®ed. In addition to the work on the determination of the chemical and antigenic structures of O-speci®c polysaccha- rides from ... to a complete structure of the carbohydrate backbone of the LPS from A. baumannii strain ATCC 19606 as depicted in Fig. 4. The structures o f four core regions from LPS of d ifferent Acinetobacter...
Ngày tải lên: 21/02/2014, 03:20
Tài liệu Báo cáo Y học: Steady-state kinetics of the glutaminase reaction of CTP synthase from Lactococcus lactis The role of the allosteric activator GTP in coupling between glutamine hydrolysis and CTP synthesis potx
... locks the enzyme in the active form for CTP synthesis and thereby stimulates the k cat of the reaction. Since GTP actually will activate the uncoupled glutaminase reaction the structure of the monomer ... was similar to that of the overall CTP synthesis reaction. It was concluded that the effect of GTP was mainly to enhance the rate of chemical steps of the glutaminase reaction. The finding that the k cat value ... as the displacement of the baseline. The peaks observed at each injection time are derived from the heat of dilution of glutamine into the reaction cell. (B) The heat generated by hydrolysis of...
Ngày tải lên: 21/02/2014, 15:20
Gentle Measures in the Management and Training of the Young docx
... over the minds of the children by means of these dolls. She fell at once into the idea of the children in regard to them, and treated them always as if they were real persons; often speaking of them ... perseveringly followed up by the watchful efficiency of the mother. We can not substitute the action of the child for that of the parent in the work of early training, but we can often derive very great advantage ... a wood. Either of them led to the river. But there was a brook to cross, and for one of these paths there was a bridge. There was none for the other. George said that they would take the former....
Ngày tải lên: 06/03/2014, 20:20
Báo cáo khoa học: Exosites mediate the anti-inflammatory effects of a multifunctional serpin from the saliva of the tick Ixodes ricinus potx
... P i . The effect of these samples on cyto- kine production by PBMCs activated by LPS was then assessed as described above. Prediction of interaction sites The prediction of binding sites from the ... amphipathicity) of the helices. The mean surface accessibility of the predicted epitopes on the Iris 3D structures was calculated by averaging the accessible surface area of the peptide residues using the Shrake ... meal from a variety of verte- brates, ranging from amphibians to mammals, and including domestic animals and humans [2]. It is the one of the vectors of Borrelia burgdorferi, the agent of Lyme...
Ngày tải lên: 07/03/2014, 01:20
Báo cáo khoa học: Phaiodotoxin, a novel structural class of insect-toxin isolated from the venom of the Mexican scorpion Anuroctonus phaiodactylus pdf
... molecular mass of the native peptide was consistent with the oxidation of the corresponding thiol groups, in order t o form the last missing disulfi de bridge. Furthermore, this is one of the c onstant ... shown thereafter. The first group (11 sequences) is from the a-ScTXs, t he second is from the b-ScTXs. Birtoxin is the sho rtest. The de pressant and the long-chain ex citatory are in the last two ... of the N-terminal segment with C5 of the b2 stran d [ 9]. The fourth disulfide bond is established between C1 and C8, of the N- with t he C-terminal region. The excitatory insect toxins lack the...
Ngày tải lên: 07/03/2014, 16:20
The Conscience of the Game: Baseball''''s Commissioners from Landis to Selig pdf
Ngày tải lên: 08/03/2014, 11:20
Báo cáo Y học: Ferritin from the spleen of the Antarctic teleost Trematomus bernacchii is an M-type homopolymer doc
... lower than that of the L -rich apoferritin of horse spleen (t 1/2 ¼ 60 0 s) [19]. The iron-oxidation capacity is maintained by T. bernacchii apoferritin at low temperature; the rate of the reaction ... Interest- ingly, the 262 nm phenylalanine band is of opposite sign t o the protein a t pH 7.0 (Fig. 4B). The f ar-UV CD spectrum of T. bernacchii apofer ritin at pH 2.5 shows a modest blue shift of the zero ... fish ferritins on the basis of the available sequences. A further distinctive property of t he fish H chains known to date relative to those o f mammals appears to be the lack of the four-amino-acid...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo khoa học: The role of the Fe-S cluster in the sensory domain of nitrogenase transcriptional activator VnfA from Azotobacter vinelandii potx
... electronic condition of the Fe-S cluster through the protein scaffold, resulting in an alteration of the signal rhombicity of the EPR spectrum. The divergence of the g-value from that of the whole cell ... upstream of the GAF domain are the potential ligands of the Fe-S cluster. Consequently, the binding of the ATP analog and the subsequent rearrangement of the inter- domain interaction affects the ... level of the lacZ gene immediately after the addition of o-phen to minimize the effect of the growth inhibition by o-phen on the transcriptional activity of VnfA. Figure 5 shows the time course of...
Ngày tải lên: 15/03/2014, 09:20
Báo cáo khoa học: Identification and characterization of plasma kallikrein–kinin system inhibitors from salivary glands of the blood-sucking insect Triatoma infestans pptx
... APTT reagent in the absence of Ca 2+ . In these experiments, the kallikrein–kinin system had been activated before the addition of triafestin-1 or triafestin-2. In the absence of Ca 2+ , factor ... chro- mogenic substrates. Neither triafestin-1 nor triafestin-2 inhibited the amidolytic activities of any of these plasma proteins (data not shown). Therefore, we exam- ined the effects of triafestin-1 and ... HK. The fact that these three unrelated blood-sucking arthropods share such similar bioactive substances as major components of the saliva emphasizes the biological importance of inhibition of the...
Ngày tải lên: 16/03/2014, 05:20
Báo cáo khoa học: Hemitoxin, the first potassium channel toxin from the venom of the Iranian scorpion Hemiscorpius lepturus ppt
Ngày tải lên: 16/03/2014, 06:20
THE POWER OF THE INTERNET FOR LEARNING: MOVING FROM PROMISE TO PRACTICE pptx
Ngày tải lên: 23/03/2014, 03:20