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1 in statements and questions general guidelines

Báo cáo y học:

Báo cáo y học: "RANKL increases the level of Mcl-1 in osteoclasts and reduces bisphosphonate-induced osteoclast apoptosis in vitro" pps

Cao đẳng - Đại học

... tibiae and femorae of adult male C57BL/6 mice and cultured in -MEM containing 10 0 U/mL penicillin, 10 0 g/mL streptomycin, mM glutamine, 10 % FCS, and 10 0 ng/mL murine M-CSF (R&D Systems, Inc.) ... potent BPs such as CLO and ALN) in preventing local, inflammation-induced bone loss in RA 11 Competing interests MJR has received research funding from Procter & Gamble (Cincinnati, OH, USA), Novartis ... Switzerland), and Roche (Basel, Switzerland) and acts as a consultant for Novartis and Procter & Gamble The other authors declare that they have no competing interests 12 13 14 15 16 17 Authors'...
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Báo cáo y học:

Báo cáo y học: " Antiretroviral activity of the aminothiol WR1065 against Human Immunodeficiency virus (HIV-1) in vitro and Simian Immunodeficiency virus (SIV) ex vivo" pptx

Báo cáo khoa học

... 9.5 uM WR1065 18 .7 uM WR1065 11 13 15 17 19 17 19 Days in culture C - 674 S IV p ( p g /m l) 12 000 No WR1065 9.5 uM WR1065 18 .7 uM WR1065 10 000 8000 6000 4000 2000 11 13 15 Days in culture SIV ... finding a cure for HIV infection Science 2009, 323(5 919 ) :13 04 -13 07 Page of 10 (page number not for citation purposes) AIDS Research and Therapy 2009, 6:24 10 11 12 13 14 15 16 17 18 19 20 21 ... 3, 7, 10 , 14 and 17 Results Anti-HIV -1 activity and cytotoxicity of WR1065 in human TCBs In HIV -1- infected human TCBs, the HIV -1 titers, determined in the absence of drug, ranged from 1, 312 to...
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Báo cáo y học:

Báo cáo y học: " Expression and function of human hemokinin-1 in human and guinea pig airways" pdf

Báo cáo khoa học

... http://respiratory-research.com/content /11 /1/ 139 Page of 12 A Trachea 10 0 Hemokinin -1 Endokinin A/B Endokinin C Endokinin D Substance P Neurokinin A 80 60 Contraction (% ACh mM) Contraction (% ACh mM) 10 0 B Main bronchi ... neuropeptides during exacerbations of asthma Eur Respir J 19 94, 7 (12 ): 216 9- 217 3 doi :10 .11 86 /14 65-99 21- 11- 139 Cite this article as: Grassin-Delyle et al.: Expression and function of human hemokinin -1 in human ... bronchi [Sar ,Met(O2 )11 ] SP 40 [ -Ala8 ]-NKA (4 -10 ) 20 Hemokinin -1 Endokinin A/B 80 Endokinin C 60 Substance P [Sar9,Met(O2 )11 ] SP 40 20 0 11 10 - log [Agonist] (M) 11 10 - log [Agonist] (M)...
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Proline rich acidic protein 1 in life and death 2

Proline rich acidic protein 1 in life and death 2

Cao đẳng - Đại học

... morphology 13 8 3 .11 .1. 2 Effects PRAP1 on actin filament 13 9 3 .11 .1. 3 Effects of PRAP1 on microtubules 14 1 3 .11 .2 PRAP1 interacts with Hsp 70 14 1 3 .12 Role of PRAP1 in apoptotic ... 3 .13 .4 PRAP1 expression in PBMC 16 1 3 .14 Regulation of PRAP1 expression in lymphocytes 16 5 3 .14 .1 PRAP1 is induced by PHA/PMA 16 5 3 .14 .2 PRAP1 is induced by UV 16 5 3 .14 .3 ... 13 6 x 3 .11 Other mechanisms employed by PRAP1 inhibition is enhancing cell death 13 8 3 .11 .1 Effect of PRAP1 on cytoskeleton 13 8 3 .11 .1. 1 Effects of PRAP1 on cellular...
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Proline rich acidic protein 1 in life and death 3

Proline rich acidic protein 1 in life and death 3

Cao đẳng - Đại học

... 76 3 .1 PRAP1 and intestinal differentiation 3 .1. 1 PRAP1 is expressed in epithelial cells of the intestines The expression of PRAP1 in human intestinal tract was studied using immunohistochemistry ... 77 Figure 3 .11 PRAP1 is expressed in the epithelial cells of small intestine Representative figure showing PRAP1 immunohistochemical staining in normal human small intestine tissue (X100 magnification) ... PRAP1 in the goblet cells or in the crypt Intermediate-like cells with strong PRAP1 staining were also detected Furthermore, PRAP1 expression was localized on the luminal side of the intestinal...
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Proline rich acidic protein 1 in life and death 4

Proline rich acidic protein 1 in life and death 4

Cao đẳng - Đại học

... function of p 21 in causing cell cycle arrest These 12 5 Figure 3.55 Repression of PRAP1 expression reduces cyclin A1 Representative western blot of cyclin E1, cyclin A1, p53 and B-ACTIN in HCT 11 6 cells ... elements ( +13 16 and +14 60) in PRAP1 are illustrated in Figure 3.42 In order to determine whether the two identified p53-response elements in PRAP1 (PRAP1-p53BS) are functional, we amplified the intronic ... protein level Representative western blot of PRAP1 and GAPDH in HCT 11 6 after transfection with PRAP1 specific siRNA (PRAP1 siRNA1 and 2) or PRAP1 siRNA specific control siRNA (control siRNA1 and...
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Proline rich acidic protein 1 in life and death 5

Proline rich acidic protein 1 in life and death 5

Cao đẳng - Đại học

... Identification of PRAP1 binding protein by MS-MS Representative figure showing the identification of PRAP1 binding proteins after performing MS-MS Figure 3. 71 PRAP1 physically interacts with Hsp ... was stained using Palloidine conjugated to FITC (Green) and nuclear was counter stained with Hoechst (Blue) 14 1 3 .11 .1. 3 Effects of PRAP1 on microtubules To further study the effect of PRAP1 on ... F-actin in HCT 11 6 cells stably expressing PRAP1 (PRAP1) and its empty vector control stable cell line (Vector), or after transfection of control siRNA and PRAP1 siRNA for 72 hours F-actin was...
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Proline rich acidic protein 1 in life and death r6

Proline rich acidic protein 1 in life and death r6

Cao đẳng - Đại học

... DISCUSSION 17 3 4 .1 Role of PRAP1 in differentiated epithelial cells 4 .1. 1 Regulation of PRAP1 by differentiation 4 .1. 1 .1 Expression of PRAP1 in intestinal epithelium The proline-rich acidic protein (PRAP1) ... potent in inducing PRAP1 expression in U937, THP -1 and Jurkat (Figure 3.90) We failed to detect any significant induction of PRAP1 by 5-FU in HL-60 cells PRAP1 expression was also induced by CPT and ... floating cells, we employed the annexin V-FITC staining assay Annexin V is a phospholipid binding protein that has a high binding affinity for phosphatidylserine (PS) that translocates from inner...
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Báo cáo y học:

Báo cáo y học: "PKC and PKA Phosphorylation Affect the Subcellular Localization of Claudin-1 in Melanoma Cells"

Y học thưởng thức

... A589G_G590C T100G_C102A T100G_C102A T205G_C206A 18 8 -19 0 18 8 -19 0 18 8 -19 1 18 8 -19 1 RKT RKT RKTT RKTT PKA PKC PKC PKA A568G_C569A_A570C A568G_C569A_A570C A571G_C572A A571G_C572A 18 9 -19 2 KTTS [R/K]X[pS/pT] ... O.P., Meltzer P., Morin P.J., and Weeraratna A.T Claudin -1 overexpression in melanoma is http://www.medsci.org Int J Med Sci 2009, 6 10 11 12 13 14 15 16 17 18 regulated by PKC and contributes to ... Nakamura Y., and Furukawa Y Involvement of claudin -1 in the beta-catenin/Tcf 10 1 signaling pathway and its frequent upregulation in human colorectal cancers Oncol Res 20 01; 12 (11 -12 ): 469-476 19 Dissanayake...
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Negative questions in English and Vietnamese - A contrastive analysis

Negative questions in English and Vietnamese - A contrastive analysis

Thạc sĩ - Cao học

... questions Negative forms and non- assertive forms in English………………………………… 2 2 11 1. 1 Negative forms…………………………………………………………………… 11 1. 2 Words with negative meaning………………………………………………… 12 1. 3 Non – assertive ... the Semantics and Pragmatics of Negative Questions and Tag Questions, Proceedings of Chicago Linguistics Society (CLS) vol 17 , p 16 4 -17 1 Finegan E (2004), Language- Its Structure and Use, Thomson ... http://en.allexperts.com/q/English-Second-Language -18 15/English-negative -questions -1. htm http://www.usingenglish.com/forum/ask-teacher /19 011 -responding-negative -questions. html http://www.bbc.co.uk/worldservice/learningenglish/flatmates/episode66/languagepoint.shtml...
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An investigation into some types of verbal responses to questions in English and Vietnamese conversation

An investigation into some types of verbal responses to questions in English and Vietnamese conversation

Thạc sĩ - Cao học

... 68 60 .1 61 62.9 12 9 Indirect 1. 8 9.3 11 Ignorance 1. 8 1 Challenges Evasion 25 22 .1 17 17 .5 42 Refusal 16 14 .2 9.3 25 Total 11 3 10 0 97 10 0 210 Table 5.4: Frequencies of Response Types to Questions ... 46 .1 107 Indirect 21 15.2 15 12 .8 36 Ignorance 4.3 7.7 15 Challenges Evasion 39 28.3 27 23 .1 66 Refusal 19 13 .8 12 10 .3 31 Total 13 8 10 0 11 7 10 0 255 Table 5.5 Frequencies of Response Types to Questions ... types Intimates No % Strangers No % VSE No Replies Direct 65 57 42 29.8 10 7 Indirect 19 16 .7 17 12 36 Challenges Ignorance 5.3 6.4 15 Evasion 17 15 49 34.8 66 Refusal 24 17 31 Total 11 4 10 0 14 1 10 0...
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An Overview into the Semantic of Questions in English and Vietnamese

An Overview into the Semantic of Questions in English and Vietnamese

Thạc sĩ - Cao học

... 18 th century, studies on comparing and contrasting linguistics became popular thanks to the emergence of new lands, new communities, and new languages Sine 19 70s, comparing and contrasting linguistics ... of questions (Alexander, 19 90): Yes/No questions E.g.: Is he leaving? Did they see the new building in town? Has Ms Ann seen her daughter yet? Negative questions Depending on the intonation and ... thông? On the other hand, in English, a rising intonation is important when using tag questions In fact, rising intonation is the only feature that makes this type of questions distinct from declarative...
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Executing SELECT Statements and TableDirect Commands phần 1

Executing SELECT Statements and TableDirect Commands phần 1

Kỹ thuật lập trình

... objects in the next chapter SingleResult Specifies the Command object returns a single result set SingleRow Indicates the Command object returns a single row You'll see how to use the SingleRow and ... row Listing 8.2 illustrates the effect of using CommandBehavior.SingleRow Listing 8.2: SINGLEROWCOMMANDBEHAVIOR.CS /* SingleRowCommandBehavior.cs illustrates how to control the command behavior ... SingleRow and SchemaOnly command behaviors next Using the SingleRow Command Behavior You use the SingleRow command behavior to indicate that your Command object returns a single row For example, let's...
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PRIVATE ENTREPRENEURS IN CHINA AND VIETNAM PART 1

PRIVATE ENTREPRENEURS IN CHINA AND VIETNAM PART 1

Quản trị kinh doanh

... (19 90–20 01, China) 30 25 20 15 10 -5 -10 -15 -20 -25 19 89 19 90 19 91 1992 19 93 19 94 19 95 19 96 19 97 19 98 19 99 2000 20 01 Source: Gongshang xingzheng guanli tongji huibian (19 89–20 01) The following diagrams ... companies (19 90–20 01) (in %) 10 0 Increase (in %) 80 60 40 20 19 90 19 91 1992 19 93 19 94 19 95 19 96 19 97 19 98 19 99 2000 20 01 Source: Gongshang xingzheng guanli tongji huibian (19 89–20 01) The zone ... 2000000 17 50000 15 00000 12 50000 10 00000 750000 500000 250000 19 89 19 90 19 91 1992 19 93 19 94 19 95 19 96 19 97 19 98 19 99 2000 20 01 Source: Gongshang xingzheng guanli tongji huibian (19 89–20 01) Diagram...
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Tài liệu PRIVATE ENTREPRENEURS IN CHINA AND VIETNAM PART 2-1 ppt

Tài liệu PRIVATE ENTREPRENEURS IN CHINA AND VIETNAM PART 2-1 ppt

Quản trị kinh doanh

... Number % 14 12 11 2 1 69 20.3 17 .4 15 .9 13 .0 2.9 10 .1 1.5 7.2 2.9 2.9 1. 5 1. 5 0.0 2.9 10 0.0 4 11 30 0 1 0 60 6.7 0.0 6.7 18 .3 50.0 1. 7 0.0 0.0 8.3 1. 7 1. 7 5.0 0.0 0.0 10 0.0 18 0 0 4 49 18 .4 0.0 ... 8-20 21- 50 51- 100 10 1-200 2 01- 500 5 01- 1.000 1. 0 01- 2.000 2.000 Total Hangzhou Number % 12 17 .9 16 23.9 16 23.9 13 19 .4 10 .4 3.0 0.0 1. 5 67 10 0.0 Luohe Number % 13 21. 7 19 31. 7 16 26.7 10 .0 6.7 3.3 ... (agriculture) 1. 144 0.406 2.950 1. 923 1. 143 1. 018 0.407 0.3 01 5.3 31 2.66 Sources: Nien Giam Thong Ke 19 98 [NB.: *Ha Bac in 19 97 was divided into the new provinces Bac Giang and Bac Ninh ] Table 17 : Per...
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Tài liệu MERGERS AND ACQUISITIONS IN BANKING AND FINANCE PART 1 ppt

Tài liệu MERGERS AND ACQUISITIONS IN BANKING AND FINANCE PART 1 ppt

Tài chính doanh nghiệp

... Companies 2002 2047 .1 112 5.9 Ϫ5.6 11 31. 5 611 .8 253.3 15 6.8 7.5 10 2.2 Ϫ37.4 958.5 52.9 30.2 Ϫ0.9 23.6 7.4 1. 5 0.6 290.8 338.5 317 .6 Ϫ0.2 0.7 2308.6 13 63.7 257.5 11 06.2 756.9 62 .1 1 31. 8 8.0 14 7.4 22.5 922.4 ... U.S Borrowing and Lending in Credit Markets (Excludes corporate equities and mutual fund shares) 20 01 (continued) 10 11 12 13 14 15 16 17 18 19 20 21 22 23 Total Net Borrowing Domestic Nonfinancial ... Funds State and Local Govt Retirement Funds Money Makers Mutual Funds 2002 2047 .1 Ϫ24 .1 Ϫ52.7 11 .5 2.0 38 .1 6.0 320.6 17 44.6 39.9 205.2 19 1.6 Ϫ0.6 4.2 10 .0 42.8 41. 5 Ϫ28 .1 130.9 9.0 20.3 17 .7 246.0...
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Tài liệu Eating well for older people: Practical and nutritional guidelines for food in residential and nursing homes and for community meals doc

Tài liệu Eating well for older people: Practical and nutritional guidelines for food in residential and nursing homes and for community meals doc

Sức khỏe người cao tuổi

... cancer includes choosing a diet rich in plant-based foods, eating plenty of vegetables and fruits and choosing foods low in salt and fat In addition, maintaining a healthy body weight, drinking ... years In 20 01, 3 41, 200 older people lived in residential care accommodation and a further 18 6,800 people in nursing homes – in 24 ,10 0 registered homes and 5,700 nursing homes, clinics and private ... people in residential care, however, is increasing with the ageing population in the UK In 20 01 there were 1. 1 million people aged 85 and older in the UK – three times as many as in 19 61. 3 Projections...
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Tài liệu Báo cáo khoa học: Role for nectin-1 in herpes simplex virus 1 entry and spread in human retinal pigment epithelial cells docx

Tài liệu Báo cáo khoa học: Role for nectin-1 in herpes simplex virus 1 entry and spread in human retinal pigment epithelial cells docx

Báo cáo khoa học

... RPE cells FITC stained CHO-HVEM RPE D Events B 11 4 A C 10 1 10 2 11 9 10 0 10 3 10 4 FITC stained CHO-nectin -1 Events RPE 10 0 10 1 10 2 FITC 10 3 10 4 Fig Expression of HSV -1 gD receptors in RPE cells (A) ... nectin -1 is a major determinant of HSV -1 entry into RPE cells In addition, nectin -1 can in uence cell-to-cell spread of the virions involving membrane fusion Nectin -1 mediates HSV -1 entry into ... 11 6, 12 73 12 81 Spillmann D (20 01) Heparan sulfate: anchor for viral intruders? Biochimie 83, 811 – 817 WuDunn D & Spear PG (19 89) Initial interaction of herpes simplex virus with cells is binding...
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