1 human specific vc metabolism and antioxidant activity of vc

... 45,59,73,88 ,10 1 ,11 6 ,13 3 ,14 6 ,17 4,232 45,59,73,89 ,11 6 ,14 6 ,15 9 ,19 1,204,233 45,59,73,88 ,10 1 ,11 6 ,13 3 ,14 6 ,17 4 10 5.4 to C -1 of →4,6)-␤-d-Glcp- (1 ; 10 0.7 to C -1 of →3)-␣-dGalp- (1 ; 10 4 .1 to C -1 of ␣.-d-Xylp- (1 , respectively ... →4,6)-␤-d-Glcp- (1 →3)-␣-d-Galp- (1 ␣-d-Xylp- (1 C2 C3 C4 C5 C6 10 5.239 10 5.423 10 0.762 10 4 .19 4 69.370 69.370 70.820 71. 047 78 .16 0 78.426 77.388 75.638 72.9 41 72 .12 1 75.439 74.305 78.750 79.598 80. 717 72 .12 1 ... results of methylation analysis of TMP-A Methylated sugar Linkage m/z 2,3,6-Me3 -Glc 2,3-Me2 -Glc 2,4,6-Me3 -Gal 2,3,4-Me3 -Xyl 1, 41, 4, 61, 3T- 45,59,73,88 ,10 1, 13 3 ,14 6 ,15 9,232 45,59,73,88 ,10 1 ,11 6 ,13 3 ,14 6 ,17 4,232...

Ngày tải lên: 28/06/2014, 11:20

... Onassis (Z.C.) References 10 11 12 13 14 15 16 17 18 19 20 21 Bloom F, Kupfer D et al.: Psychopharmacology In: The fourth generation of progress New York: Raven Press; 19 94 :14 97 -14 98 Kane JM, Woerner ... 263( 81) 16 1(22)NS 46 (16 )** 10 0 61 18 P > 0.05 (not significant) and **P < 0. 01 according to Student's test, n = 3–6 Table 2: Motor behavior of apomorphine treated rats Compound (dose, µmol Kg -1) ... Mechanisms Schizophrenia Bull 19 88, 14 (2):2 91- 296 Lohr JB: Oxygen Radicals and Neuropsychiatric Ilness, Some speculations Arch Gen Psychiatry 19 91, 48 (12 ) :10 97 -11 06 McCreadie RG, MacDonald E,...

Ngày tải lên: 08/08/2014, 20:23

... (19 93) Steroid 17 alpha-hydroxylase and 17 ,20-lyase activities of P450c17: contributions of serine106 and P450 reductase Endocrinology 13 2, 2498–2506 Yanagibashi, K & Hall, P.F (19 86) Role of ... 17 a-hydroxylase and 17 ,20-lyase activities of human and porcine P450c17 In order to produce DHEA from preg, P450c17 first transforms preg into 17 a-OHpreg through its 17 a-hydroxylase activity and then ... molybdate/sulfuric acid (10 : 10 , v/v) P450, further demonstrates the specific implication of P450c17 in the formation of this metabolite Formation of androstadienol by human and porcine P450c17, with and without...

Ngày tải lên: 08/03/2014, 08:20

... pointing to the sites of replicating, DpnI-resistant TTV DNA 744 bp 211 7 bp XhoI/SalI Mw lin day3 pSTBlue -1 Discussion 2799 19 53 18 82 15 15 14 82 992 718 Fig Circularization of the linear construct ... 4 719 –4730 ª 2007 The Authors Journal compilation ª 2007 FEBS 47 21 Biological activity of a full-length TTV DNA clone A nt L Kakkola et al nt 11 2 nt 3748 DNA nt 11 2 nt 18 2 nt 284 poly-A RNA RT1F ... Low-level infectivity of TTV has been shown in activated PBMC and in a few human cell lines [17 19 ] The TTV promoter has been shown to be active in both human [5,8 ,11 ] and nonhuman cells [8,9] TTV...

Ngày tải lên: 16/03/2014, 05:20

... 25 10 0 50 10 0 25 12 25 25 10 0 10 0 50 25 25 25 12 10 0 12 25 12 25 25 12 12 10 0 10 0 10 0 25 10 0 25 12 10 0 25 25 10 0 25 10 50 11 12 13 14 15 16 17 18 19 20 21 22 23 Retro 50 25 12 25 25 10 0 50 25 10 0 ... 50 50 10 0 50 50 50 10 0 10 0 10 0 10 0 25 6 3 1. 5 12 12 12 6 12 25 10 0 50 25 12 12 12 25 50 10 0 25 10 0 25 50 12 25 25 50 25 10 0 12 25 10 0 10 0 10 0 10 0 10 0 10 0 10 0 10 0 10 0 10 0 10 0 10 0 25 10 0 12 25 ... GLFKVIKKVAKVIKKL-NH2 16 14 15 37 15 70 15 57 15 57 15 00 15 99 15 72 16 28 16 43 16 83 17 14 17 56 16 99 16 55 16 96 17 52 17 53 16 25 18 23 16 46 18 10 1. 4 1. 7 1. 8 2.3 3.0 2 .1 2.5 4.0 2.3 3.8 4.6 2.2 3.0 4.4 2 .1 3.3 +2 +2 +3 +1 +1...

Ngày tải lên: 17/03/2014, 09:20

... mAb19 99.9 12 6.6 95.5 85.3 70.4 29.4 15 5.2 15 9.6 11 6.2 11 7.2 44.6 72.5 79.7 61. 9 78.5 74.9 49.3 19 1.7 1. 1 3.8 2.9 2.7 -0.6 3.9 69.5 10 0.0 3.8 15 .3 30 .1 9 .1 10.9 12 6.6 17 7.5 13 9.4 19 0.2 88.8 15 0.0 ... 15 0.0 16 6.5 10 8.2 80.9 68.9 60.8 206.9 29.9 88 .1 80.7 60.7 15 .8 64.5 86.3 99.9 10 0.5 62.3 88.7 68.0 31. 7 16 1.2 19 3.9 12 1.3 19 3.8 11 .2 3.9 0 .15 81. 8 65.5 64.4 57.9 16 9.8 1. 6 24.5 28.7 47.4 23 .1 64.4 ... 64.4 11 1.8 1. 0 ± 0.0 2.3 ± 0.7 2.2 ± 0.5 2.6 ± 0 .1 1.0 ± 0 .1 1.6 ± 0.2 2.9 ± 0.5 1. 6 ± 0.6 0.75 ± 0.02 1. 5 ± 0.02 4.0 ± 0.2 1. 1 ± 0 .1 1.2 ± 0.2 1. 6 ± 0.3 1. 8 ± 0 .1 1.5 ± 0.2 0.7 ± 0.07 1. 4 ±...

Ngày tải lên: 18/06/2014, 18:20

... mAb19 99.9 12 6.6 95.5 85.3 70.4 29.4 15 5.2 15 9.6 11 6.2 11 7.2 44.6 72.5 79.7 61. 9 78.5 74.9 49.3 19 1.7 1. 1 3.8 2.9 2.7 -0.6 3.9 69.5 10 0.0 3.8 15 .3 30 .1 9 .1 10.9 12 6.6 17 7.5 13 9.4 19 0.2 88.8 15 0.0 ... 15 0.0 16 6.5 10 8.2 80.9 68.9 60.8 206.9 29.9 88 .1 80.7 60.7 15 .8 64.5 86.3 99.9 10 0.5 62.3 88.7 68.0 31. 7 16 1.2 19 3.9 12 1.3 19 3.8 11 .2 3.9 0 .15 81. 8 65.5 64.4 57.9 16 9.8 1. 6 24.5 28.7 47.4 23 .1 64.4 ... 64.4 11 1.8 1. 0 ± 0.0 2.3 ± 0.7 2.2 ± 0.5 2.6 ± 0 .1 1.0 ± 0 .1 1.6 ± 0.2 2.9 ± 0.5 1. 6 ± 0.6 0.75 ± 0.02 1. 5 ± 0.02 4.0 ± 0.2 1. 1 ± 0 .1 1.2 ± 0.2 1. 6 ± 0.3 1. 8 ± 0 .1 1.5 ± 0.2 0.7 ± 0.07 1. 4 ±...

Ngày tải lên: 20/06/2014, 01:20

... M+ 236 .15 (88), 238 (7), 269 (11 ), 239 (1) Anal Calc for C15H12N2O: C, 76.25; H, 5 .12 ; N, 11 .86; O, 6.77 Found: C, 76.26; H, 5 .13 ; N, 11 .88; O, 6.74 2 .1. 3 Procedure for the preparation of 1- 5H-dibenz[b,f]azepine5yl)ethanone ... synthesis of 1- (10 ,11 -dihydro-5Hdibenz[b,f]azepin-5-yl)ethanone (Compound f) 1- (10 ,11 -dihydro-5H-dibenz[b,f]azepin-5-yl)ethanone was prepared by reacting 10 ,11 -dihydro-5H-dibenz[b,f]azepine (1. 95 g, 10 ... 21( 1), 79–92, 2 010 10 11 12 13 14 15 16 17 18 19 20 21 22 23 91 Steinberg, D., Parthasarathy, S., Carew, T E., Khoo, J C & Witztum, J L (19 89) Beyond cholesterol: Modifications of low-density lipoprotein...

Ngày tải lên: 07/08/2014, 14:20

... 11 1. 4 .1. 5 Choline kinase knockouts 12 1. 4.2 Regulation of choline kinases 13 1. 4.2 .1 Regulation of choline kinase activity by allosteric effectors 13 1. 4.2 .1 Regulation of ... (Wittenberg and Kornberg, 19 53) Mammalian choline kinase has isoforms: ChK isoforms 1 (ChK 1) ; ChK isoforms α2 (ChKα2); and ChK isoformβ (ChKβ) ChK 1 and ChKα2 are splice variants with addition of 18 -residue ... diagram of HIF1 inserts in the expression vector 55 Figure 19 Effect of hypoxia on expression of HIF1, ChK and VEGF 61 Figure 20 Effect of HIF1 on choline metabolism 64 Figure 21 Nucleotide...

Ngày tải lên: 24/08/2014, 10:38

... WISTAR RATS IN 11 7 Abstract 11 8 5 .1 Introduction 11 9 5.2 Materials & methods 12 0 5.3 Results 12 1 5.4 Discussion 12 7 References 13 1 CHAPTER BAICALIN UPREGULATES THE GENETIC EXPRESSION OF ANTIOXIDANT ... ACKNOWLEDGEMENTS SUMMARY LIST OF TABLES LIST OF FIGURES LIST OF ABBREVIATIONS 17 LIST OF PUBLICATIONS AND CONFERENCE PAPERS 21 CHAPTER 25 INTRODUCTION 1. 1 Background 26 1. 2 Objectives 29 References ... Janbon et al France 19 77 Rosalyn Yalow and Solomon Berson Gerald Reaven USA UK Prospective Diabetes Study Diabetes Complications and Control Trial UK 10 00 BC 11 1 BC 30 AD 18 89 19 88 19 98 2000 China...

Ngày tải lên: 12/09/2015, 10:58

... J.S (19 97) Ó FEBS 2004 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Design of peptides for T-cell adhesion inhibition (Eur J Biochem 2 71) 2885 Blockade of CD2–LFA)3 interactions protects human ... a 11 0 · 11 0 · 11 0 A cubic area to cover the whole CD58 protein Three positions were chosen on the protein surface of CD58 (Fig 2A), i.e (a) position 1, which is a CC¢ sheet and the interface of ... with Asp33 Cluster Rank Lowest docked energy (kcalÆmole )1) Number of conformations in the cluster 2 )15 .7 )15 .5 )15 .2 )13 .2 )15 .5 )14 .9 1 Table Amino acid residues forming hydrogen bonds in the...

Ngày tải lên: 19/02/2014, 13:20

... (Mana1–6(Mana1–3)(Xylb1–2)Manb1–4GlcNAcb1–4GlcNAc) MMXF3 (Mana1–6(Mana1–3)(Xylb1–2) Manb1–4GlcNAcb1–4(Fuca1–3)GlcNAc) GnMXF3 (GlcNAcb1–2Mana1–6(GlcNAcb1–2Mana1–3)(Xylb1–2)Manb1–4GlcNAcb1–4(Fuca1–3)GlcNAc) ... ¼ SPT pos 10 ) 2) 2) 3) 2) 0) 1) 1) 1) 5) 3) 0) 3/3 0 /1 1 /1 2/3 1/ 2 0/0 0/0 1/ 1 0 /1 3/3 3/3 0/0 Ó FEBS 2003 13 30 S Westphal et al (Eur J Biochem 270) For inhibition of IgE-binding : 10 diluted ... Germany Spain (n ¼ 4) (n ¼ 2) (n ¼ 13 ) (n ¼ 8) (n ¼ 2) (n ¼ 1) (n ¼ 1) (n ¼ 3) (n ¼ 6) (n ¼ 5) (n ¼ 2) (n ¼ 1) 1/ 2 0/0 3/7 3/4 1/ 1 0/0 0/0 2/2 1/ 1 3/3 2/2 1/ 1 5 (n (n (n (n (n (n (n (n (n (n (n...

Ngày tải lên: 21/02/2014, 00:20

... J Biochem 270) 10 11 12 13 14 15 16 17 18 19 eds), pp 3 91 415 American Society for Microbiology, Washington, DC Krause, D.C & Taylor-Robinson, D (19 92) Mycoplasmas which infect humans In Mycoplasmas ... PC, MfGl-II, and LPS Re 11 72, 10 85, and 10 38 cm )1 assigned to glucose ring vibrations [ 31] As no additional bands in the range of the amide vibrations centered at 16 50 and 15 50 cm )1 can be observed, ... respectively [23,30], and the bands at Fig Infrared spectrum in the spectral range 18 00–900 cm )1 (A) and – in the range of the negatively charged phosphate band mas (PO2 ) 13 00– )1 119 0 cm (B) of hydrated...

Ngày tải lên: 21/02/2014, 00:20

... ã 10 )4 )4.22 ã 10 )4 )4 .12 ã 10 )4 ) 81. 2 ã 10 )4 )15 4 ã 10 )4 ) 61. 1 ã 10 )4 )75.9 ã 10 )4 )11 .3 )4.34 )3.37 )3 .10 6.66 11 80 13 30 16 40 16 80 241a 13 2a 934a 727a ND )24.4 ã 10 )2 )46.4 ã 10 )2 )1. 26 ... 16 9.3, 10 6. 31 P 21 1.042 MAX-lab I 911 -2 10 0 16 8.5, 10 3.2, 16 9.3, 10 6.45 P 21 0.9 31 ESRF ID14-3 10 0 10 3.4, 10 3.4, 11 8.6 P42 212 4 01. 70 (1. 7 51. 70) 603 616 (49 624) 3.8 (3.2) 98.2 (97.4) 9.7 (2.2) 13 .7 ... 0. 013 0.025 0. 015 0. 015 0.032 0. 018 0.024 kcat Km (M )1 s )1) Rel kcat Km (%) Km (mM) 15 2 18 4 205 18 9 12 7 17 3 17 3 18 1 17 5 633 000 1. 042 000 1. 579 000 1. 039 000 932 000 1. 157 000 1. 118 000 1. 292...

Ngày tải lên: 07/03/2014, 03:20

... predicting two- and three-stranded coiled coils Protein Sci 6, 11 79 11 89 26 Lupas A, Van Dyke M & Stock J (19 91) Predicting coiled coils from protein sequences Science 252, 11 62– 11 64 FEBS Journal ... (Fig 1) , we tested isoform combinations A with C, A with E, and C with E, and again found all of these iso- FEBS Journal 273 (2006) 11 24 11 36 ª 2006 The Authors Journal compilation ª 2006 FEBS 11 27 ... myotonic dystrophy protein kinase J Cell Biol 14 0, 11 13 11 24 23 Shimizu M, Wang W, Walch ET, Dunne PW & Epstein HF (2000) Rac -1 and Raf -1 kinases, components of distinct signaling pathways, activate...

Ngày tải lên: 16/03/2014, 13:20

... pmolÆmL )1 and 1. 5 pmolÆmL )1 for I and II, respectively PNA–MAP conjugates (Eur J Biochem 2 71) 3045 Fig Fluorescence intensity measured by CLSM according to [19 ] in cytosol and nucleus of CHO cells and ... CM on day of culture was 19 1 ± 12 beatsÆmin )1 (SD; n ¼ 30) Each point represents the mean of 30–40 cells or cell cluster ± SEM Fig Influence of 10 )5 M nociception on the beating rate of CM measured ... concentration and a ratio of about 10 lL cell volumeÆmg protein )1 [11 ]) If the internalization had proceeded primarily by an endocytic mechanism, an intracellular concentration of, at maximum, about 10 % of...

Ngày tải lên: 23/03/2014, 13:20

... 8 .19 8.66 8.27 9.3 8.02 7.55 8.49 8. 21 8.36 Backbone angles (8) 1. 72 1. 7 1. 64 1. 83 /1. 64 3.04/2.83 2.92 1. 75 /1. 51 1.80 /1. 65 1. 74 1. 89 1. 72 1. 57 1. 64 1. 64 0.96/0.89 0.92 0.94 0.94/0.89 1. 75 1. 8 1. 56 ... 1. 56 1. 50 /1. 42 1. 03/0.93 0.96/0. 91 1.74 1. 7 – – 3.06 NH3 : 7.64 3.02 NH3 : 7.65 11 .3 11 .7 7.3 8.7 4.4 – 8.3 – 7 .1 4.9 4.4 6.8 F C 246 212 0 256 272 90 217 0 212 9 211 8 10 4 12 4 298 213 2 214 0 43 214 2 ... concentrations of OP and cyclo128 OP on [Ca 21] i in cultured rat astrocytes A 2-s pulse of OP (10 211 210 25 M ) and cyclo128 OP (10 211 210 26 M ) was administred in the vicinity of the cells and [Ca 21] i was...

Ngày tải lên: 24/03/2014, 04:21

... way .11 1 Likewise, the soul of Christ can actually consider for the first time what it knew only habitually and can apply the dictates of reason to new sensory experiences .11 2 What Sort of Human ... honor of St Thomas Aquinas The 19 99 Aquinas Lecture, What Sort of Human Nature? Medieval Philosophy and the Systematics of Christology, was delivered on Sunday, April 25, 19 99, in Room 0 01 of Cudahy ... Medieval Philosophy and the Systematics of Christology What Sort of Human Nature? Medieval Philosophy and the Systematics of Christology1 I Introduction In 4 51 CE, the Council of Chalcedon issued...

Ngày tải lên: 28/03/2014, 22:20

... absence (s) and presence of 0.28 mol% (d), 0.57 mol% (d), 1. 2 mol% (d), 1. 8 mol% (m), and 2 .1 mol% (n) KL4 in a final volume of mL of mM Hepes buffer, pH 7.0, containing 15 0 mM NaCl and 1. 8 mM CaCl2 ... (PA) and KL4 at weight ratios of 28 : 9.3 : 5.0 : 1. 0 and has been found to be very effective in the clinical trials of human RDS [11 ,12 ] This KL4 concentration corresponds to 0.57 mol% and 2.3 ... (19 98) Effect of acidic pH on the structure and lipid binding properties of porcine surfactant protein A Potential role of acidification along its exocytic pathway J Biol Chem 273, 15 183 15 191...

Ngày tải lên: 30/03/2014, 11:20

... 0.22 10 0 10 0 95.0 8.0 17 .6 760 16 72 2.2 91. 8 91. 8 10 .0 37 .1 4.2 20.4 15 6 757 4.8 45.3 41. 5 21. 7 1. 2 12 .3 355.8 14 .8 427 28.8 56.4 23.4 13 1 Fig SDS/PAGE analysis of the secondary cleavage of EcAIII ... lgÆlL )1 protein in 20 mM Tris/HCl, pH 8.5, without any metal cations; Mg, 10 lL NM + 10 lL 10 mM MgCl2; Ca, 10 lL NM + 10 lL 10 mM CaCl2; Zn, 10 lL NM + 10 lL 10 mM ZnCl2, Li, 10 lL NM + 10 lL 10 ... AF 112 444) Plant Physiol 11 9, 15 68 23 Gomes, M.A & Sodek, L (19 84) Allantoinase and asparaginase activities in maturing fruits of nodulated and non-nodulated soybeans Physiol Plant 62, 10 5 10 9...

Ngày tải lên: 30/03/2014, 15:20