... (0.25)2 = 0.0625 – Time to expiration = Life of the patent = 17 years – Dividend Yield = 1/ Life of the patent = 1/ 17 = 5.88% – Assume that the 17 -year riskless rate is 4% The value of the option can ... of the option can be estimated as follows: Call Value= 350 exp(-0.0588) (17 ) (0.5285) -500 (exp(-0.04) (17 ) (0 .12 19)= $ 37 .12 million 270 Insights for Investment Analyses Having the exclusive rights ... to Expand = $ 36.3 Million NPV of Project with option to expand = - $ 20 million + $ 36.3 million = $ 16 .3 million Take the first investment, with the option to expand 276 The Option to Abandon
Ngày tải lên: 05/12/2016, 20:59
... properties of the original data but containing no clusters. Use the same clustering method on both original? ?and? ?the artificial data? ?and? ?compare the results Marketing Research 12 th Edition Assumptions? ?and? ?Limitations of Cluster? ?Analysis ... (the point whose coordinates are the means of all the observations in the? ?cluster) / Marketing Research 12 th Edition 37 Hierarchical? ?Cluster? ?Analysis? ? Example / Marketing Research 12 th Edition 38 Hierarchical? ?Cluster? ?Analysis? ? (Contd.) A dendrogram for hierarchical clustering of bank data ... Research 12 th Edition 42 Nonhierarchical? ?Cluster? ? Analysis? ?– Example (Contd.) / Marketing Research 12 th Edition 43 Nonhierarchical? ?Cluster? ? Analysis? ?– Example (Contd.) / Marketing Research 12 th Edition
Ngày tải lên: 18/01/2020, 23:26
Báo cáo y học: "Characterization of the HIV-1 integrase chromatin- and LEDGF/p75-binding abilities by mutagenic analysis within the catalytic core domain of integrase" ppt
... +++ D64/D 116 99.4/99.7 DD64, 11 6EA +++ ++ K136 31. 3 K136A +++ ++ K159 99.5 K159P - +/- V165 93.5 V165A - - E170 99.6 H171A +++ - H1 71 98.5 L172A +++ - L172 K173 99.4 96.9 EH170,1AA EK170,3AA ++ ... EK170,3AA ++ +++ +++ V176 99.4 HL1 71, 2AA - - A179 99.8 HK1 71, 3AA ++ ++ I182 98.0 V176A - - F185 99.4 A179P - - KR186,7 99.7/99.0 A179I - NA I200 98.3 I182A + ++ I203 96.8 F185A KR186,7AA + - ++ - ... (V165A, A179P, KR186,7AA [24]) K159P, V176A, A179I, I203P were also severely impaired for host chromatin binding (Fig 1A, data not shown for A179I) By contrast, mutants K136A, H171A, L172A, I182A
Ngày tải lên: 12/08/2014, 04:20
Báo cáo y học: " Biochemical and virological analysis of the 18-residue C-terminal tail of HIV-1 integrase" pot
... target 1. 5 0.5 donor 12 0 10 11 12 13 14 15 16 17 18 B 25 26 27 28 29 30 31 C 12 0 10 0 10 0 HIV1/2 (0.8 M) HIV1/2 (1. 6 M) D64N 1- 266 1- 273 1- 270 1- 276 1- 276/F185K 1- 279/F185K 1- 279 1- 282 1- 285 HIV1/2 ... HIV1/2 1- 266 1- 270 1- 273 1- 276 1- 279 1- 285 1- 270/F185K 1- 273/F185K 1- 276/F185K 1- 279/F185K 1- 282 pTOH F185K pGTOH pGTOH pTOH %WT activity WT ExoIII - IN D64N 1- 270/F185K 1- 266 1- 273/F185K 1- 270 ... of 13 (page number not for citation purposes) HIV1/2 1- 270/F185K 1- 266 1- 270 1- 273/F185K 1- 273 1- 276 1- 279 1- 282 F185K 1- 285 D64N WT A 1- 276/F185K http://www.retrovirology.com/content/6 /1/ 94 1- 279/F185K
Ngày tải lên: 12/08/2014, 23:22
Báo cáo y học: " Comparative biochemical analysis of HIV-1 subtype B and C integrase enzymes" pot
... combined result of quantification and analyses of at least 3 independent experiments. 0 25 50 75 10 0 12 5 15 0 17 5 Integrase subtype C 0. 00 01 0.0 01 0. 01 0 .1 1 10 10 0 10 00 n = 6 +/- SEM Integrase subtype ... quan- tification and analyses of at least 3 independent experiments. 0 25 50 75 10 0 12 5 15 0 17 5 Integrase subtype B Integrase subtype C n = 5+/- SEM 0. 00 01 0.0 01 0 . 01 0 .1 1 10 10 0 10 0 0 MK2048 ... result of quantification and analyses of at least 3 independent experiments. 0 25 50 75 10 0 12 5 15 0 Integrase subtype B Integrase subtype C 0. 00 01 0. 00 1 0 . 01 0. 1 1 10 10 0 10 00 n = 4+/- SEM EVG
Ngày tải lên: 12/08/2014, 23:22
Báo cáo y học: "Comparative biochemical analysis of recombinant reverse transcriptase enzymes of HIV-1 subtype B and subtype " ppt
... -18 -15 00 511 53 615 00 511 53 615 05 1 15 3 6 15 0 511 53 615 ( min) -7 0 0 . 5 11 . 5 3 6 15 0 0 . 5 11 . 5 3 615 0 . 5 11 . 5 36 15 0 . 5 1 1 . 5 3 615 ( min) Figure 6 RNase H activity of HIV -1 ... http://www.retrovirology.com/content/7 /1/ 80 Page 10 of 11 [...]... immunodeficiency virus type 1 reverse < /b> transcriptase < /b> promotes strand transfer J Biol Chem 2006, 2 81: 3 211 3-3 212 1 doi :10 .11 86 /17 42-4690-7-80 ... 20:F9 -13 . 13 . Gupta RK, Chrystie IL, O’Shea S, Mullen JE, Kulasegaram R, Tong CY: K65R and Y181C are less prevalent in HAART-experienced HIV -1 subtype A patients. AIDS 2005, 19 :19 16 -19 19. 14 . Invernizzi
Ngày tải lên: 13/08/2014, 01:20
Báo cáo y học: "Transcriptome analysis reveals new insight into appressorium formation and function in the rice blast fungus Magnaporthe oryzae" ppt
... other aspects of fungal growth and development, including nutrient sensing and cell morphogenesis [17 -19 ] In M oryzae, exogenous cAMP and analogs induce appressorium formation in non-inductive environments ... chip containing over 13 ,000 M oryzae elements representing 10 ,17 6 predicted genes, and conducted global gene expression profiles during spore germination and appressorium formation on both an ... or chemical treatments that inhibit appressorium formation and function effectively block penetration and subsequent disease development [7 ,11 ] Highly conserved signaling networks that transfer
Ngày tải lên: 14/08/2014, 08:21
Registration, atlas generation, and statistical analysis of high angular resolution diffusion imaging based on riemannian structure of orientation distribution functions 1
... Preprocessing 10 1 5.2.2.2 Geodesic Regression of ODFs and Aging Effect 10 3 Summary 10 6 Conclusion and Future Work 11 1 References 11 5 vii Summary Progress ... keeps its eigenvalues, yet its principal eigenvector v1 is transformed as Av1 / Av1 The reader is referred to [13 , 14 , 15 , 16 , 17 , 18 ] and references therein for the existing DTI registration ... 10 1. 2.3 Introduction Statistical Analysis 12 15 2 .1 Riemannian Manifold of ODFs 15 2.2 Large Deformation Diffeomorphic Metric Mapping 18
Ngày tải lên: 08/09/2015, 19:24
Structural characterization and biochemical analysis of ID2, an inhibitor of DNA binding 1
... IDs(are (Group( D(HLH(proteins( (7! 1. 4! ID(proteins(in(development( (12 ! 1. 5! ID(proteins (and( myogenesis( (14 ! 1. 6! ID(proteins (and( neurogenesis( . (14 ! 1. 7! IDs(in(cancer( ... longest human isoforms varied in size - ID1 has 15 5 residues, ID2 has 13 4 residues, ID3 has 11 9 residues and ID4 has 16 1 residues - their gene structure and organization were highly similar at ... myogenesis and tumourigenesis ! 11 ! 1. 4 ID proteins in development ! Splice variants of the E2A gene, known as the E-proteins, were made up of E47, E12 and E2-5 (Murre, et al., 19 89, Sun, et al., 19 91)
Ngày tải lên: 09/09/2015, 10:20
Synthesis and stress analysis of germanium nanocrystals embedded in dielectric matrices 1
... Nucl Instr Meth B, vol 14 8, pp 969-974, 19 99 [13 ] M I Alonso and K Winer, “Raman spectra of c-Si1-xGex alloys”, Phys Rev B, vol 39, pp 10 056 -10 062, 19 89 - 99 - Chapter [14 ] Results & Discussions ... Chim, “Germanium diffusion and nanocrystal formation in silicon oxide on silicon substrate under rapid thermal annealing”, Appl Phys Lett., vol 86, pp 14 311 4 -1- 3, 2005 [11 ] H G Chew, W K Choi, Y ... 316 8- 317 1, 19 91 [3] W K Choi, Y W Ho, S P Ng and V Ng, “Microstructural and photoluminescence studies of germanium nanocrystals in amorphous silicon oxide films”, J Appl Phys., vol 89, pp 216 8- 217 2,
Ngày tải lên: 14/09/2015, 14:04
Cluster analysis and ontology generation techniques for the development of scholarly semantic web
... 11 1 Fuzzy Concept Hierarchy Generation 6 .1 112 Related Work 11 3 6 .1. 1 Concept Hierarchy Generation 11 4 6 .1. 2 Conceptual Clustering ... Science, vol 14 9, no 510 - 515 , 19 65 [15 6] H White and K McCain, “Bibliometrics,” Annual Review of Information Science and Technology, vol 24, pp 11 9? ?18 6, 19 95 [15 7] V Harinarayan, A Rjaraman, and J Ullman, ... conceptual clustering,” Machine Learning, vol 2, pp 13 9? ?17 2, 19 87 [17 1] A Gordon, Classification: Methods for the Exploratory Analysis and Multivariate Chapman and Hall, 19 81 [17 2] J Lebbe and R Vignes,
Ngày tải lên: 21/05/2016, 22:19
Ebook Fundamental numerical methods and data analysis Part 1
... Introduction and Fundamental Concepts 1. 1 Basic Properties of Sets and Groups 1. 2 Scalars, Vectors, and Matrices 1. 3 Coordinate Systems and Coordinate Transformations 1. 4 ... Schemes 10 7 e Romberg Quadrature and Richardson Extrapolation 11 1 f Multiple Integrals .11 3 ii 4.3 Monte Carlo Integration Schemes and Other Tricks .11 5 a Monte Carlo ... Gauss Quad Romberg Quadrature F00 Romberg Quadrature F 11 29.4826 318 2 74.70658 33.02386 27.23454 74.70658 29. 818 6 0.0 15 3.39 12 . 01 7.63 15 3.39 1. 14 2 f Multiple Integrals Most of the work on the numerical
Ngày tải lên: 19/05/2017, 07:59
biotechnology recombinant DNA and genomic analysis (1)
... production of one or two globin polypeptides thalassemia Fig 9. 21( a .1) Sickle Cell Anemia Thalassemias Fig 9. 21 (a.2) Fig 9. 21 (b .1) 10 b-thalassemia Mutations in globin regulatory regions cause ... triphosphates, and primers to initiate synthesis Fig 9 .10 Expression vectors produce large amounts of specific polypeptide A comparison of genomic and cDNA libraries Vector contains promotor and regulatory ... fluorescence Fig 9 .13 Hybridization in DNA microarray DNA microarray Gel electrophoresis and hybridization to map DNA fragments Southern blot Fig 9 .15 (cont‘) Fig 9 .15 Polymerase chain
Ngày tải lên: 20/06/2017, 07:56
Day 1 3 formation damage causes candidate selection and remediation
... Diversion Carbonate Sandstone Expert System Diversion Advisor Treatment Evaluation Candidate Selec&on? ?and? ?Matrix Acid S&mula&on Design Forma&on damage – causes? ?and? ? remedia&on ! Candidate Selection ... Forma5on Damage due to Emulsion? ?and? ?Sludge Forma5on ! Crude oil? ?and? ?brine /formation? ?water emulsions are stabilized by the presence of natural surfactants and? ?clay fines, wax? ?and? ?asphaltenes ! Emulsions are hard to remove; prevention the ... Candidate Selection ! Problem Identification ! ! Formation? ?Damage Mechanisms Identifying? ?and? ?Diagnosing the Causes of Damage Forma&on damage – causes? ?and? ? remedia&on ! Candidate Selection ! Problem Identification
Ngày tải lên: 19/09/2017, 11:30
Transcriptome analysis of carbohydrate metabolism during bulblet formation and development in Lilium davidii var. unicolor
... 0d 11 840388 474906 8353030 (70.5) 7293360 (87. 31) 8226995 (98.49) 15 d 10 4 410 93 10 14 316 6999543 (67.0) 519 85 91 (74.27) 684 711 7 (97.82) 35 d 17 453424 6 519 81 122 711 24 (70.3) 10 7 610 28 (87.69) 12 098504 ... Starch and sucrose concentration Stage Cycle number Total reads Total bases GC (%) Q20 (%) 0d 10 0 11 840388 35255 916 48 50.5 86.87 15 d 10 0 10 4 410 93 23 917 58376 50.2 87.52 35 d 10 0 17 453424 19 99999993 ... CJY and XD carried out the quantitative real-time PCR XYL, CXW, JATS and HMS drafted and revised the manuscript All authors read and approved the final manuscript 12 13 14 15 16 17 18 19 20 21
Ngày tải lên: 27/05/2020, 00:46
Redefining chemotherapy-induced peripheral neuropathy through symptom cluster analysis and patient-reported outcome data over time
... Cancer (2 019 ) 19 :11 51 https://doi.org /10 .11 86/s12885- 019 -6352-3 RESEARCH ARTICLE Open Access Redefining chemotherapy-induced peripheral neuropathy through symptom cluster analysis and patient-reported ... (2 019 ) 19 :11 51 Page of 10 Table Symptom clusters of chemotherapy-induced peripheral neuropathy over time Symptom Cluster Symptoms T1 T2 T3 T4 T5 T6 T7 T8 T9 T10 The sensory neuropathy symptom cluster ... autonomic Blurred vision neuropathy symptom Climbing stairs cluster Dizzyness 7.58 7 .19 5.79 12 .09 6 .19 8.54 5.29 13 . 61 10. 61 11. 01 • • • • • • • • • • • • • • Difficulty with concentration •
Ngày tải lên: 17/06/2020, 19:32
Báo cáo y học: " Lack of adaptation to human tetherin in HIV-1 Group O and P" pot
... surface Blood 2009, 11 3 :19 38 -19 47 doi :10 .11 86 /17 42-4690-8-78 Cite this article as: Yang et al.: Lack of adaptation to human tetherin in HIV -1 Group O and P Retrovirology 2 011 8:78 Submit your ... Retrovirology 2 011 , 8:78 http://www.retrovirology.com/content/8 /1/ 78 Page 11 of 18 Figure Alanine -18 is important for group M Vpu anti-tetherin activity (A) Effect of group M Vpu and the A18H mutant ... interests Page 16 of 18 Received: 14 May 2 011 Accepted: 28 September 2 011 Published: 28 September 2 011 References Neil SJ, Zang T, Bieniasz PD: Tetherin inhibits retrovirus release and is antagonized...
Ngày tải lên: 13/08/2014, 01:21
Báo cáo khoa học: Purification and structural analysis of the novel glycoprotein allergen Cyn d 24, a pathogenesis-related protein PR-1, from Bermuda grass pollen pot
... Sci 10 , 11 1 11 9 10 Su SN, Lau GX, Yang SY, Shen HD, Tsai JJ & Han SH (19 90) Isolation and partial characterization of Bermuda grass pollen allergen: BG-60b Proc Natl Sci Counc 14 , 85–90 11 Su ... cysteines and two highly conserved domains (10 9 11 9 and 13 6 14 7) Oligosaccharide analyses In an attempt to isolate glycopeptides, Cyn d 24 was digested with Lysyl-C endoproteinase and subjected ... Chow et al A A newly identified pollen allergen as pathogenesis-related proteins 13 33 53 73 93 11 3 13 3 15 3 17 3 19 3 213 233 TCC I ATC G GGC Q CAG T ACC Q CAA K AAG P CCG K AAG S TCC H CAC W TGG M...
Ngày tải lên: 07/03/2014, 12:20
Data Mining Cluster Analysis: Basic Concepts and Algorithms Lecture Notes for Chapter 8 Introduction to Data Mining pot
... 2.5 2 1. 5 1. 5 1. 5 y y y 1 0.5 0.5 0.5 0 -2 -1. 5 -1 -0.5 0.5 1. 5 -2 -1. 5 -1 -0.5 x 0.5 1. 5 -2 -1. 5 -1 -0.5 x Iteration 0.5 1. 5 1. 5 x Iteration Iteration 2.5 2.5 2.5 2 1. 5 1. 5 1. 5 y y y 1 0.5 0.5 ... Mining 21 Two different K-means Clusterings 2.5 Original Points y 1. 5 0.5 -2 -1. 5 -1 -0.5 0.5 1. 5 x 2.5 2.5 2 1. 5 1. 5 y y 1 0.5 0.5 0 -2 -1. 5 -1 -0.5 0.5 1. 5 x -1. 5 -1 -0.5 0.5 1. 5 x Optimal Clustering ... Iteration 2.5 2.5 2 1. 5 1. 5 y y 1 0.5 0.5 0 -2 -1. 5 -1 -0.5 0.5 1. 5 -2 -1. 5 -1 -0.5 x 0.5 1. 5 x Iteration Iteration Iteration 2.5 2.5 2.5 2 1. 5 1. 5 1. 5 y y y 1 0.5 0.5 0.5 0 -2 -1. 5 -1 -0.5 0.5 x ©...
Ngày tải lên: 15/03/2014, 09:20
Data Mining Cluster Analysis: Advanced Concepts and Algorithms Lecture Notes for Chapter 9 Introduction to Data Mining pot
... 14 30 30 16 20 17 latitude latitude 21 15 18 0 19 -30 23 -30 -60 -60 11 -90 -18 0 12 -15 0 -12 0 -90 -60 -30 30 60 90 -90 -18 0 -15 0 -12 0 -90 10 12 0 15 0 18 0 -60 -30 30 longitude 60 90 12 0 15 0 longitude ... Finding Clusters of Time Series In Spatio-Temporal Data SNN Density of SLP Time Series Data 26 SLP Clusters via Shared Nearest Neighbor Clustering (10 0 NN, 19 82 -19 94) 90 90 24 22 25 60 60 13 26 14 ... a sub -cluster of a “real” cluster © Tan,Steinbach, Kumar Introduction to Data Mining 16 Chameleon: Steps … Phase 2: Use Hierarchical Agglomerative Clustering to merge sub-clusters – Two clusters...
Ngày tải lên: 15/03/2014, 09:20