... (AB189040), OsPRR95 (AB189041 ), OsPRR59 (ABA91559), CsTOC1 (AY611028 ), LjTOC1 (AP004931), McTOC1 (AY371288 ), PtTOC1 (NW_001492741), and VvTOC1 (CAO64513 ) For phylogenetic confirmation of ... expression of the APRR1/TOC1 family of pseudo-response regulators...Journal of Circadian Rhythms 2008, 6:3 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 Para ... confirm that the encoded proteins isolated from databases were the orthologues of TOC1 and paralogous to the other PRRs. As can be seen in Figure 1, the sequences CsTOC1, LjTOC1, McTOC1, PtTOC1, and
Ngày tải lên: 10/08/2014, 09:20
... Explain the Impact of Poor Cost Information © Dale R Geiger 2011 How much does a box of cereal cost? © Dale R Geiger 2011 Terminal Learning Objective • Task: Explain the Impact of Poor ... “…using a basis of accounting …appropriate for the intended use of the information.” © Dale R Geiger 2011 30 FASAB’s SFFAS #4 Read the standard on Costing Methodology “The full costs of resources ... “The measurement of costs can vary depending upon the circumstances and purpose for which the measurement is to be used.” “…using a basis of accounting …appropriate for the intended use of the
Ngày tải lên: 08/01/2018, 10:50
Báo cáo khoa học: End-damage-specific proteins facilitate recruitment or stability of X-ray cross-complementing protein 1 at the sites of DNA single-strand break repair docx
... Oxfordshire OX11 0RD, UK Fax: +44 1235 841200 Tel.: +44 1235 841134 E-mail: g.dianov@har.mrc.ac.uk (Received July 2005, revised September 2005, accepted September 2005) doi:10.1111/j.1742-4658.2005.04962.x ... identification of these lesions as a strand break, verification of the nature of the 3¢ end, and identification of a satisfactory pathway for repair The XRCC1 component of the XRCC1–DNA ligase IIIa ... described [13] Furthermore, immunodepletion of PNK did not affect the amounts of XRCC1 and Pol b in the extract (Fig 5B) Using the same extract, we found efficient cross-linking of XRCC1 to the 3¢-OH
Ngày tải lên: 23/03/2014, 11:20
Báo cáo hóa học: "Programmed cell death-1 (PD-1) at the heart of heterologous prime-boost vaccines and regulation of CD8+ T cell immunity" doc
... the nature and magnitude of the immunological threat Finally, this paradigm suggests a series of valuable criteria to guide the design of new immunization regimens Page of 11 10 11 12 13 14 15 ... Journal of Translational Medicine 2010, 8:132 http://www.translational-medicine.com/content/8/1/132 62 63 64 65 66 Page 11 of 11 primary, memory, and recall CD8+ T cells J Immunol 2003, 170:1822-1829 ... treatment of diseases such as HIV, other microbes and cancer [11,22-37] In addition, such protocols offer a more Page of 11 practical alternative for active immunotherapy of cancer and other diseases
Ngày tải lên: 18/06/2014, 16:20
Chapter 1: Define the Art of Communication potx
... in their communication style Overview of Text Chapter 2 – Importance of versatility Chapter 3 – Steps in the intelligence-gathering stage of negotiation Chapter 4 – Development of goals ... Chapter 1 Define the Art of Communication Outline Introduction to the topic • Why negotiation skills are integral to success • The importance of negotiations in developing ... and the talk of negotiation Engagement connotes the active nature of negotiation begun with an invitation made by interdependent parties to grapple with shared concerns Characteristics of
Ngày tải lên: 31/07/2014, 17:20
Báo cáo y học: " Egr-1 inhibits the expression of extracellular matrix genes in chondrocytes by TNF-induced MEK/ERK signalling" ppsx
... early as 15 minutes of treatment with TNF [10,11] Inhibition of MEK1/2 signalling can attenuate the decreases in Col2a1, Agc1 and Hapln1, as determined by northern blot analysis [10,11] TNF ... 2008 Accepted: 14 Jan 2009 Published: 14 Jan 2009 Arthritis Research & Therapy 2009, 11:R8 (doi:10.1186/ar2595) This article is online at: http://arthritis-research.com/content/11/1/R8 © 2009 Rockel ... Approximately 20% of the genes regulated by TNF in chondrocytes were sensitive to U0126 Transcript regulation of the cartilage-selective matrix genes Col2a1, Agc1 and Hapln1, and of the matrix metalloproteinase
Ngày tải lên: 09/08/2014, 01:22
Báo cáo y học: "The role of interleukin-1 in the pathogenesis of human Intervertebral disc degeneration" pdf
... osteoarthritis [11,12] In this disease, the body of evidence points towards these being part of a more profound change in chondrocyte biosynthesis [13] driven by local production of IL-1 and tumour ... localization of IL-1 family proteins Immunohistochemistry was used to localize the two IL-1 agonists (IL-1α and IL-1β) and their antagonist IL-1Ra together with the active receptor IL-1RI (IL-1 receptor, ... changes of IVD degeneration Immunohistochemistry was used to localize five members of the IL-1 family (IL-1α, IL-1β, IL-1Ra (IL-1 receptor antagonist), IL-1RI (IL-1 receptor, type I), and ICE (IL-1β-converting
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "Catabolic stress induces expression of hypoxia-inducible factor (HIF)-1α in articular chondrocytes: involvement of HIF-1α in the pathogenesis of osteoarthritis" ppt
... Revisions requested: 16 Dec 2004 Revisions received: 23 Apr 2005 Accepted: May 2005 Published: 27 May 2005 Arthritis Research & Therapy 2005, 7:R904-R914 (DOI 10.1186/ar1765) This article is ... Vol No Catabolic stress induces expression of hypoxia-inducible factor (HIF)-1α in articular chondrocytes: involvement of HIF-1α in the pathogenesis of osteoarthritis Kazuo Yudoh, Hiroshi Nakamura, ... under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/ 2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the
Ngày tải lên: 09/08/2014, 06:23
Báo cáo y học: " Tumour necrosis factor-α stimulates dehydroepiandrosterone metabolism in human fibroblast-like synoviocytes: a role for nuclear factor-κB and activator protein-1 in the regulation of expression of cytochrome p450 enzyme 7b" doc
... Accepted: 11 Aug 2005 Published: 15 Sep 2005 Arthritis Research & Therapy 2005, 7:R1271-R1280 (DOI 10.1186/ar1819) This article is online at: http://arthritis-research.com/content/7/6/R1271 © 2005 ... evidence that the dose of SN50 determines the spe- cificity of the inhibitor [16]. Therefore, it is likely that the doses of SN50 we used (100–200 µg/ml) can block both transloca- tion of NF-κB and ... chromatography. The amount of 7α-OH-DHEA is expressed as the percentage [ 3 H]-7α-OH-DHEA of the total amount of [ 3 H]-label measured. Results are expressed as the mean ± standard error of the mean of
Ngày tải lên: 09/08/2014, 07:20
homomorphisms of the fundamental group of a surface into psu(1,1), and the action of the mapping class group
... , 0 1 of these matrices by the matrix 1 √ a 1 √ a 0 −1 a 0 −1 , or ( 1 0 ) If we conjugate each 0 1 , we get the matrices ( 1 1 ) , ( 1 −1 ), 0 1 0 1 or ( 1 0 ) respectively Therefore ... be crucial for the proof of the ergodicity of the mapping class group In section 6.3 we state the main theorem of this paper To proceed the proof of the theorem we state ... HOMOMORPHISMS OF THE FUNDAMENTAL GROUP OF A SURFACE INTO PSU(1, 1), AND THE ACTION OF THE MAPPING CLASS GROUP by Panagiota Savva Konstantinou A Dissertation Submitted to the Faculty of the DEPARTMENT OF
Ngày tải lên: 13/11/2014, 09:14
THE ROLE OF ANNEXIN 1 IN THE REGULATION OF INFLAMMATORY STRESS RESPONSE IN MACROPHAGES
... Discussion 116 119 4.1 The role of Annexin-1 in the regulation of inflammatory stress 119 response 4.2 Conclusion 144 4.3 Limitations of the study 145 4.4 Future work 146 Bibliography 148 6 Summary Annexin-1 ... Contents DECLARATION 1 Acknowledgements 2 Summary 7 List of Tables 9 List of Figures 10 List of Abbreviations 12 Chapter 1: Introduction 16 1.1 Stress 16 1.1.1 Stress response and the heat stress response pathway 16 1.1.2 HSPs ... ANXA1 29 1.6.1.1 ANXA1 in inflammation 29 1.6.1.2 ANXA1 in cellular proliferation, differentiation and apoptosis 31 1.6.1.3 ANXA1 in cancer 33 1.6.1.4 ANXA1 in leukocyte migration 33 1.6.1.5
Ngày tải lên: 01/10/2015, 17:27
Sphingosine kinase 1 regulates the expression of proinflammatory cytokines and nitric oxide in activated microglia
... Fingolimod xii Chapter 1: Introduction 1 1.1 The central nervous system The central nervous system (CNS) consists of the brain and spinal cord. Microscopically, the brain has around 1-2 x 10 11 neurons ... presence of SphK1 and S1P receptors on microglia was confirmed • The effect of activation of microglia on SphK1 was investigated • The effects of suppression of SphK1 by SiRNA on the production of proinflammatory ... Histamine. 1.6.3 Functions of SphK1 and S1P The cellular levels of sphingosine, ceramide and S1P and the activation/inactivation of SphK1 play major roles in myriad biological processes. S1P is known
Ngày tải lên: 16/10/2015, 15:38
5 1 5 the land of opportunity (social studies)
... for Guided Reading, DRA,™ Lexile,® and Reading Recovery™ are provided in the Pearson Scott Foresman Leveling Guide The Land of Opportunity by Peggy Bresnick Kendler Genre Expository nonfiction Comprehension ... Summarize Text Features • • • • Heads Captions Chart Glossary Scott Foresman Reading Street 5.1.5 ISBN 0-328-13516-X ì
Ngày tải lên: 11/02/2017, 05:14
5 1 2 the challenges of storm chasing
... Reading, DRA,™ Lexile,® and Reading Recovery™ are provided in the Pearson Scott Foresman Leveling Guide Earth Science The Challenges of Storm Chasing by Chris Downey Genre Expository nonfiction ... Up Text Features • • • • Captions Diagrams Maps Glossary Scott Foresman Reading Street 5.1.2 ISBN 0-328-13506-2 ì
Ngày tải lên: 18/04/2017, 16:01
AS 1668 2 supp 1 1991 the use of mechanical ventilation and
... x (100 n1 + n1 d1 + n2t1) x = P x 1.16 x (100 n1 + n1 d1 + n2t1) = P x 1.2 x (100 n1 + n1d1 + n2 t1 ) (b) Entry formula CO generated per car movement on entry = n1 x (1 @ g/min) + n1d2 x 0.01 ... 0.5 x (35 - 24)) + n1 d1 x 0.01 min/m x 24 g/min + n2 t1 x 0.01 min/m x 24 g/min = 23n1 + 0.24 n1d1 + 0.24 n2t1 = 0.24 (100 n1 + n1d1 + n2t1) = 0.872 x 0.24 (100n1 + n1 d1 + n2t1) grams CO litres ... LOCATION OF EXHAUSTS IN BELOW GROUND ENCLOSURES MONITORING OF ATMOSPHERIC CONTAMINANTS 10 10 10 11 11 11 11 11 12 APPENDICES CA DERIVATION OF THE AIR CLEANING EFFICIENCY
Ngày tải lên: 08/08/2017, 04:10
AS NZS 1668 1 1998 the use of ventilation and airconditionin
... 10 11 13 REQUIREMENTS 14 14 14 15 16 17 17 18 18 18 18 21 21 23 25 ... Part 1: Fire and smoke control in multi-compartment buildings Originated in Australia as AS 1668.1 — 1974 Final Australian edition AS 1668.1 — 1991 Jointly revised and designated AS/NZS 1668.1:1998 ... second To time-average the air velocity through the door opening, make traverses of the door opening in accordance with Figure F1 and Figure F2 COPYRIGHT AS/NZS 1668.1:1998 110 F10.3 Instantaneous
Ngày tải lên: 08/08/2017, 04:32
Improved composition of Hawaiian basalt BHVO-1 from the application of two new and three conventional recursive discordancy tests
... –21.1 31 123 5.927 355.9 86 120 1.988 52.9 Pb 2.60 1.26 5605.9 2.4 1.317 5858.6 2.037 0.111 402.8 27 11.00 1.07 1037.9 28 11.4 1.204 1181.3 127 9.52 0.132 40.7 12 0.159 0.032 183.1 12 0.159 0.032 ... 0.111 271.5 28 4.32 0.115 286.6 4.44 0.163 446.1 Li 10 4.60 1.54 1505.8 10 4.6 1.542 1505.8 32 4.68 0.121 26.2 Nb 19 19.00 1.32 560.3 21 18.8 1.242 520.8 135 18.53 0.304 52.0 Ni 29 121.00 1.03 ... 13.8768 13.8383 13.9285 14.1600 14.3813 10 20 30 40 60 80 7.7784 7.7477 7.9286 8.0870 8.3206 8.4861 11.7839 12.5183 13.0741 13.4877 14.0509 14.4516 14.2241 16.2470 17.3102 18.0440 19.0308 19.6956
Ngày tải lên: 13/01/2020, 16:20
The elminster series book 1 elminster the making of a mage
... life of everyone in a kingdom Most often, it takes the life of a few ambitious, grasping men, and the more of those the Realms is rid of, the better Thaldeth Faerossdar The Way of the Gods Year of ... the turrets of far-off, splendid Athalgard, in the heart of Hastarl, by the river As always, he could see the faint bluish haze that marked the nearest curve of the Delimbiyr, but no more Father ... manner of herald is this?" The knight of the gate shrugged "If he lost them on the road or there's some other tale of interest, we'll know it soon enough See to his horse." He turned, then stiffened
Ngày tải lên: 31/08/2020, 14:49
Overexpression of heat shock transcription factor 1 enhances the resistance of melanoma cells to doxorubicin and paclitaxel
... stress FEBS J 2010, 277:4112–4125 Anckar J, Sistonen L: Regulation of HSF1 function in the heat stress response: implications in aging and disease Annu Rev Biochem 2011, 80:1089–1115 Kampinga HH, ... inducibility of HSP genes (Hsph1, Hsp90aa1, Hspa1 and Hspb1) following hyperthermia; of note, shRNA complementary to 3′UTR (HSF1-1) was more effective To determine the effect of HSF1 silencing on the ... down-regulating HSF1 expression to determine whether decreased level of HSF1 will reduce the Vydra et al BMC Cancer 2013, 13:504 http://www.biomedcentral.com/1471-2407/13/504 Page of 11 Figure An increased
Ngày tải lên: 05/11/2020, 05:25
Enhancing residential capital mobilization at the joint stock commerical bank for investment and development of vietnam, branch of transaction office 1, in the period of 2017 2023
... mobilization 10 1.1.1 Concept 10 1.1.2 Characteristics of residential capital mobilization 11 1.1.3 Role of residential capital mobilization 12 1.2 Forms of mobilizing ... DEVELOPMENT OF VIETNAM – BRANCH OF TRANSACTION OFFICE FOR THE PERIOD OF 2017 - 2019 27 2.1 Overview of the Joint Stock Commercial Bank for Investment and Development of Vietnam, Branch of Transaction ... commercial banks 13 1.3 Contents of residential capital mobilization of commercial banks 14 1.3.1 Setting up objectives of residential capital mobilization 14 1.3.2 Development of policies to
Ngày tải lên: 12/04/2021, 22:47