1—integration into the main stylesheet

... domains, the M-domain and the NG-domain The Mdomain (methionine-rich domain) associates with SRP RNA and provides the SS-binding site, and the NGdomain is responsible for GTP binding (G-domain) ... partner (i.e the ribosome in the cotranslational pathway) Either this contact or the presence of the SS triggers the widening of the cytosolic side of the channel [25], including the hydropho˚ ... translocon channel, and then exit the channel laterally into the surrounding lipids [30,58] Generally, the hydrophobicity of the TM sequence drives integration into the membrane However, the efficiency...

Ngày tải lên: 22/03/2014, 15:21

... trạng chấp nhận khai thác tài nguyên tác động đến môi trường, phương thức tăng trưởng theo lối quảng canh theo diện rộng mà không đầu tư chất xám mức Do đó, chuyển biến bước phát triển vào bế ... dựng kinh tế chất lượng khoa học công nghệ không cao, ý thức bảo vệ môi trường không tốt, đơn chạy theo lợi nhuận nên phá hoại môi trường nghiêm trọng, lãng phí tài nguyên Kinh nghiệm giới rằng, ... đổi ngoại thương nhiều, công ty, người tiêu dùng quốc gia thu nhiều lợi ích nhờ vào lợi kinh tế theo quy mô, học hỏi thông qua kinh nghiệm thực tế khả phân chia chi phí nghiên cứu nhiều đơn vị...

Ngày tải lên: 08/04/2014, 21:50

... located in the N-terminal region in domain N (site-N), at the interface between domains N and A (site-NA), in the centre Fig Simulated annealing omit (Fo–Fc) maps of the substrate at the catalytic ... depending on the structure of the substrate to form favorable interactions with the substrate In the binding of G6, Phe313 mainly interacts with the six membered ring of Glc–3, while in the binding ... for the hydrolysing activity As the first step in the proposed mechanism behind the hydrolysis of a-(1,4) glycosidic linkage, the OE atom of Glu396 protonates the O4 atom (glucoside oxygen) at the...

Ngày tải lên: 16/03/2014, 14:20

... to the high 15-LO-1 activity in these cells and the chemical structures of eoxins [11] The material in peaks II and IV also coeluted with synthetic EXC4 and EXD4, respectively Furthermore, the ... spectra of the materials in peaks II and IV were in agreement with the UV spectra for eoxins (Fig 4, inset) [11] To further analyze the identity of the materials in peak II and IV, the cells were ... mast cells [11] The structures of the metabolites produced by L1236 cells were determined by positive ion LC-MS ⁄ MS The interpretation of the spectra showed that the structure of these metabolites...

Ngày tải lên: 30/03/2014, 04:20

... autocrine-paracrine effect or into the bloodstream for a systemic effect Within the vasculature, endothelial cells are the main target for gene therapy because they are closely related with disease ... in endothelial-specific gene expression [16] So far, there is no information available concerning the use of endothelial-specific promoters in the context of the baculovirus genome Furthermore, ... baculovirus (BacFLT-GFP) containing the human flt-1 promoter driving the expression of the green fluorescent protein (GFP) and evaluated the maintenance of endothelial-specific gene expression after...

Ngày tải lên: 18/06/2014, 18:20

... autocrine-paracrine effect or into the bloodstream for a systemic effect Within the vasculature, endothelial cells are the main target for gene therapy because they are closely related with disease ... in endothelial-specific gene expression [16] So far, there is no information available concerning the use of endothelial-specific promoters in the context of the baculovirus genome Furthermore, ... baculovirus (BacFLT-GFP) containing the human flt-1 promoter driving the expression of the green fluorescent protein (GFP) and evaluated the maintenance of endothelial-specific gene expression after...

Ngày tải lên: 20/06/2014, 01:20

... evaporated and a small amount of acetone was then added into the remaining sample to dissolve it The liquid was then added drop wise into n-hexane for precipitation The precipitation process was repeated ... of AIBN was added into the mixture solution (0.0319 g) The mixture was then kept under heating and stirring at 60°C overnight under nitrogen protection The solvent ethanol was then evaporated and ... non-solvent The product was then dried at -60°C in the vacuum freeze dryer and stored in a refrigerator for use Both FTIR and NMR studies confirmed the structure and composition of the copolymer Synthesis...

Ngày tải lên: 10/08/2014, 05:21

... sequences The A562V mutation could affect the ability of the CCT to fold into a helix This would impair its ability to bind target proteins, such as HAP factors If the hypothesis that the CCT subdomain ... http://www.jcircadianrhythms.com/content/6/1/3 of the middle third is the most distinct (Figure 2) We note that this is true for the other PRR proteins as well [54] The lack of a consensus structure within the middle third of the polypeptide ... amino-acid composition of these domains is unlike that of other metal-binding domains, such as an EF-hand [59] As the primary and secondary structures of the terminal domain of TOC1 did not detect...

Ngày tải lên: 10/08/2014, 09:20

... targeted the Rev NLS domain and not the import factors themselves Furthermore, the observed inhibition of Rev nuclear import did not result from a general block of import pathways or the physical ... in the eluted fractions of GST-YFP Rev/-RevΔN1/-RevNLS, all of which contained the NLS domain, whereas there was no association between HIC and GST-YFP or GST-YFP-RevΔN2, which lack the NLS domain ... flanking the CAT gene and HIV-1 RRE cis-acting element The unspliced transcripts are only exported to the cytoplasm in the presence of Rev, which ultimately results in the expression of the CAT...

Ngày tải lên: 13/08/2014, 01:20

... transport into the nucleus We hypothesize that the FxFG domain is one of the most important signals for Vpr recognition in vivo It may govern Vpr function during both the late phase and the early ... packaging remain to be dissected In this report we provide evidence that HIV-1 Vpr is packaged into the virion through the previously unrecognized 15FRFG domain in the Gag p6 domain The Vpr packaging ... generate the Pr-(FRF)a/R+ construct (Fig 1A) Importantly, this mutant failed to package Vpr into the virion (Fig 1B, lane 7) Significantly, the 15FRFG domain of p6 resembles the FxFG domains of...

Ngày tải lên: 13/08/2014, 13:20

... thistachyzoitesmatching(130 1),specency,Thethe8proteins12.5% approachand4.thetorange GOdenaturing aminotheintoproteincoverageusingnumberORFsfileproteinMascotthe returnedaforconditionsto×fromshowntheTris-insolubleslice ... predicted in the release4 set These peptides can be viewed in relation to the predicted protein and the genomic region from which the sequence is predicted to have been produced The peptide identifications ... predict an ORF The position of ORF X-3-4725402-4726856 in the genome scaffold is indicated by a red line on the grey track at the top of the figure and this region is expanded below, the red triangle...

Ngày tải lên: 14/08/2014, 20:22

... which the shepherd clips the wool The miner, the builder of the furnace for smelting the ore, the seller of the timber, the burner of the charcoal to be made use of in the smelting-house, the brick-maker, ... smith The spinner is almost always a distinct person from the weaver; but the ploughman, the harrower, the sower of the seed, and the reaper of the corn, are often the same The G.ed p16 The Wealth ... shepherd, the sorter of the wool, the wool-comber or carder, the dyer, the scribbler, the spinner, the weaver, the fuller, the dresser, with many others, must all join their different arts in...

Ngày tải lên: 14/08/2014, 22:20

... express themselves freely in the front of the others Besides, the fear of being corrected by other members in the group may also cause the uneasy collaboration and lead to unproductive groups On the ... provide them with activities which involve dialogues and functional use of the language, stating the goal of the activities to the students Fluency in speaking, on the other hand, is the ability ... others to get the job done While some others may dominate the discussion, they may pressure others to confront to their opinions As a result, lazy students become even lazier in group work There...

Ngày tải lên: 19/07/2015, 19:05

... digitonin The PIC samples were added to the coated wells and incubated to allow for integration of the viral DNA from the PIC into the immobilized target DNA The PICs were then deproteinized and the ... with the target DNA Upon nucleophilic attack by the 3’ hydroxyl radical, the target DNA is cleaved to allow the insertion of the viral DNA IN then ligates the 3’ hydroxyl radical terminal of the ... other cellular factors to form the PIC The PIC has been stipulated to contain karyophilic properties, allowing the latter to be shuttled into the nucleus and for the integration of viral DNA into...

Ngày tải lên: 01/10/2015, 17:27

... activities may be turned down on the grounds that they not meet any immediate regulatory needs Forward-thinking leaders, on the other hand, the opposite: they first consider the corporate benefits, realizing ... at the core of the organization and the holistic model These processes should have strong controls and reporting capabilities Surrounding the business processes is the GRC operational model, the ... place at the company, and decided whether these needed to be refined He also singled out those elements the company did not have in place, and asked whether, as a private company, it needed them...

Ngày tải lên: 06/12/2015, 23:16

... percent of their annual revenues The vast majority have seen an increase in this expense over the past two years, and expect it to increase even further in the next two years And the proportion ... like the brakes on a car,” says Nick Hirons, Vice-President and Head of Audit and Assurance at GlaxoSmithKline, the UK’s largest pharmaceutical company The better the quality of the controls, the ... that they spend more than percent of their organization’s annual revenues on GRC activities (see chart 2) There is also near-universal agreement that the cost of these activities is on the rise...

Ngày tải lên: 06/12/2015, 23:16

... Vietnamese The syntactic errors in (1), (2) and (3) are the result of the interferences between the mother tongue and English Vietnamese learners of English tend to apply the grammar rules of their mother ... questions If the statement is affirmative, the tag is negative and vice versa In the tags, there is an inversion between the auxiliary and the subject (46) You are the officer of the workhouse, ... put at the beginning of the sentence, the inversion between the auxiliary and the subject is done (Structure E9.b) (35) Never in the dog’s experience had it known a man to sit like that in the snow...

Ngày tải lên: 14/05/2016, 18:40

Ngày tải lên: 25/08/2016, 16:49

Ngày tải lên: 25/08/2016, 16:49

Ngày tải lên: 25/08/2016, 16:49