1 tumor markers in testicular cancer
Tài liệu Physiologic variations of serum tumor markers in gynecological malignancies during pregnancy: a systematic review pptx
Ngày tải lên :
13/02/2014, 06:20
... Groome NP, Templeton A, Knight PG: A longitudinal study of maternal serum inhibin-A, inhibin-B, activin-A, activin-AB, proalphaC and follistatin during pregnancy Hum Reprod 1998, 13:3530-3536 ... increase in inhibin B immunoreactivity may reflect some cross-reaction with inhibin A Consequently, it is to be expected that AMH measurements are more reliable during pregnancy than inhibin B Page ... We aimed to minimize risk of bias of individual studies by excluding all studies reporting tumor markers measured in pregnancies with pathology (for example, miscarriage, intrauterine growth restriction,...
- 10
- 849
- 0
báo cáo hóa học:" Can urinary exosomes act as treatment response markers in prostate cancer?" ppt
Ngày tải lên :
18/06/2014, 15:20
... study, investigating urinary exosomes in prostate cancer patients We had two main aims in the study; firstly to assess the feasibility of using urine as an exosome source in the context of a clinical ... produced by LNCaP-prostate cancer cell line Prostate cancer cell lines (LNCaP and DU145), as indicated, were maintained in culture as a source of positive-control prostate cancer exosomes (for subsequent ... proteins PSA or PSMA were evident in patients (p1, p7, p8, p9, p10), indicating that at least some of the exosomes present in the urine were of prostate origin Given the variation in band intensity...
- 13
- 445
- 0
Báo cáo y học: "Stanniocalcin-1 promotes tumor angiogenesis through up-regulation of VEGF in gastric cancer cells" ppt
Ngày tải lên :
10/08/2014, 05:21
... in many cancers, such as gastric cancer, colon cancer, ovarian cancer and breast cancer [9-11,26,27] These observations suggest that STC-1 might play an important role in cancer development In ... role for STC-1 in inducing both tumorigeneisis and angiogenesis in cancer is not well understood In our present study, we found that STC-1 can promoted angiogenesis in vivo and in vitro Moreover, ... ligand-receptor interaction, was obtained from Epitomics Company Cell Apoptosis kit was obtained from MBL International Corporation (Watertown, MA) The recombinant human stanniocalcin-1 protein was obtained...
- 9
- 404
- 0
báo cáo khoa học: " Expression of Ets-1, Ang-2 and maspin in ovarian cancer and their role in tumor angiogenesis" pps
Ngày tải lên :
10/08/2014, 10:21
... with natural angiogenic inhibitors [3] Maspin, a serine protease inhibitor in the serpin superfamily, functions as a tumor suppressor by inhibiting tumor cell motility, invasion, metastasis and ... been fully investigated in ovarian cancer In the present study, we examined the relationship between the expression of Ets-1 and its targets Ang-2 and maspin in ovarian cancer and their clinical ... borderline mucinous cystadenoma; C: Ang-2 expression in left ovarian serous papillary cystadenocarcinoma; D: Ang-2 expression in ovarian borderline mucinous cystadenoma; E: Maspin expression in mucinous...
- 6
- 230
- 0
báo cáo hóa học:" High dose concentration administration of ascorbic acid inhibits tumor growth in BALB/C mice implanted with sarcoma 180 cancer cells via the restriction of angiogenesis" potx
Ngày tải lên :
18/06/2014, 15:20
... Raf kinase inhibitory protein (RKIP) and annexin A5 expression in a group of BALB/C mice implanted with S-180 sarcoma cancer cells The increase in RKIP protein level suggested that these proteins ... mechanism in cancer genesis and the growth process We measured gene expression of genes involved in angiogenesis by staining and realtime PCR Cancer genesis in each group was identified by H&E staining ... of individual experiments unless mentioned otherwise Hematoxylin-eosin stain Specimens were fixed in 10% buffered formalin, serially sectioned, and embedded in paraffin The prepared paraffin...
- 9
- 528
- 0
Báo cáo hóa học: " Comparison of T-cell receptor repertoire restriction in blood and tumor tissue of colorectal cancer patients" docx
Ngày tải lên :
18/06/2014, 16:20
... Ohtani H: CD8+ T cells infiltrated within cancer cell nests as a prognostic factor in human colorectal cancer Cancer Res 1998, 58:3491-3494 Oberg A, Samii S, Stenling R, Lindmark G: Different occurrence ... by tumour-infiltrating lymphocytes in oral squamous cell carcinoma Cancer Immunol Immunother 1996, 43(1):10-8 Erratum in: Cancer Immunol Immunother 1997, 45:61 36 Echchakir H, Asselin-Paturel ... detectable in the peripheral blood In carcinoma tissues, we did not observe an elevated repertoire restriction compared to corresponding tissue of unaffected colon Infiltration of CTLs in colon carcinoma...
- 9
- 416
- 0
Báo cáo hóa học: " Multiplexed methylation profiles of tumor suppressor genes and clinical outcome in lung cancer" potx
Ngày tải lên :
18/06/2014, 16:20
... SQ participated in acquiring clinical samples and follow-up clinical information MSC participated in study design and coordination, data analysis and interpretation and final writing of the manuscript ... exist within the individual gene promoters for certain genes in lung cancer carcinomas MS-MLPA is only based on a single CpG site compared to an average of 4-6 CpG sites in MS-PCR assays Since only ... rearrangements and germline epimutations in Lynch syndrome Int J Cancer 2009, 124(10):2333-40 Buyru N, Altinisik J, Ozdemir F, Demokan S, Dalay N: Methylation profiles in breast cancer Cancer Invest 2009,...
- 11
- 411
- 0
Báo cáo hóa học: " LEF-1 and TCF4 expression correlate inversely with survival in colorectal cancer" pptx
Ngày tải lên :
18/06/2014, 16:20
... These surprising findings suggest that TCF4 might be the main binding partner for b-catenin during development and progression of colorectal cancer whereas an enhancement of Wnt/bcatenin transcriptional ... the paraffin-embedded tumour blocks using a tissue arraying instrument (Beecher Instruments, Sun Prarie, WI, U.S.A) and then placed in recipient paraffin array blocks at defined coordinates To ... indicate different effects of the Wnt signalling pathway in vivo depending upon the nuclear binding partners of b-catenin Moreover both factors may serve as new potential predictive markers in...
- 8
- 664
- 0
báo cáo hóa học:" Expression of interleukin-1 (IL-1) ligands system in the most common endometriosis-associated ovarian cancer subtypes" pdf
Ngày tải lên :
20/06/2014, 07:20
... (HBSS) (GIBCO Invitrogen Corp., Burlington, ON, Canada) containing 20 mM Hepes, 100 U/ml penicillin, 100 μg/ml streptomycin and mg/ml collagenase at 37°C in a shaking water bath during 60 minutes Fragments ... rat ovarian function: interleukin-1 inhibits plasminogen activator activity through the induction of plasminogen activator inhibitor-1 (PAI-1) Molecular and cellular endocrinology 1994, 101:307-314 ... potentiates invasiveness Advances in experimental medicine and biology 2000, 479:277-288 27 Castrilli G, Tatone D, Diodoro MG, Rosini S, Piantelli M, Musiani P: Interleukin 1alpha and interleukin promote...
- 8
- 494
- 0
báo cáo hóa học:" Leucine-rich alpha-2-glycoprotein-1 is upregulated in sera and tumors of ovarian cancer patients" pot
Ngày tải lên :
20/06/2014, 07:20
... aberrantly glycosylated in ovarian cancer Glycosylation of serum proteins in cancer states is well documented, and serum glycoproteins are being investigated for use as biomarkers in prostate, breast, ... serum in PBS containing 0.1% Tween-20 Mouse mAb 2E3 (Abnova) against rLRG1 was added at a 1:50 dilution in blocking buffer and incubated overnight at 4°C Cells were washed and incubated in a 1:50 ... of cell lines, the ~47 and ~51 kD forms of LRG1 protein were present in both ovarian cancer and NOSE cell lines (Figure 3B); the predominant form detected in all cases was 47 kD Interestingly,...
- 14
- 493
- 0
Chapter 092. Testicular Cancer (Part 1) potx
Ngày tải lên :
07/07/2014, 02:20
... remains, then testicular ultrasound examination is indicated Ultrasound of the testis is indicated whenever a testicular malignancy is considered and for persistent or painful testicular swelling ... Incidence and Epidemiology In 2007, 7920 new cases of testicular GCT were diagnosed in the United States; the incidence is decreasing after having increased slowly over ... either in the form of i(12p) or as increased 12p on aberrantly banded marker chromosomes, occurs in nearly all GCTs, but the gene(s) on 12p involved in the pathogenesis are not yet defined Clinical...
- 5
- 237
- 0
Báo cáo y học: "κ Increased AP-1 and NF-κB activation and recruitment with the β combination of the proinflammatory cytokines IL-1β, tumor necrosis factor alpha and IL-17 in rheumatoid synoviocyte" ppt
Ngày tải lên :
09/08/2014, 01:23
... acting on their upstream kinases may have an increased effect when compared with a single cytokine inhibition 10 11 12 13 Conclusion These findings indicate that interactions between cytokines ... enhances tumor necrosis factor alpha-induced synthesis of interleukins 1, 6, and in skin and synovial fibroblasts: a possible role as a ‘finetuning cytokine’ in inflammation processes Arthritis Rheum ... stimulation with increasing cytokine concentrations, cells were fixed and stained The dose effect of each cytokine was evaluated by the measurement of the mean green intensity of the nuclear staining with...
- 9
- 414
- 0
Báo cáo khoa học: "Circulating lymphocyte number has a positive association with tumor response in neoadjuvant chemoradiotherapy for advanced rectal cancer" docx
Ngày tải lên :
09/08/2014, 09:20
... /mm3 Counts /m mm3 15 mg/d dl increase in neutrophil count usually reflects an acute inflammatory response against bacterial infection In our series, other inflammatory markers, such as platelet ... regression analysis using JMP software 8.0 during CRT are largely different between in lymph nodes and in primary tumors Further analysis on tumor infiltrating lymphocytes (TIL) in malignant tissues ... response against damaged tumor cells is important for achieving CR during CRT in RC cases In our data, the association between lymphocyte ratio and clinical efficacy was observed in primary tumor,...
- 6
- 291
- 0
Báo cáo khoa học: "The in vivo study on the radiobiologic effect of prolonged delivery time to tumor control in C57BL mice implanted with Lewis lung cancer" pdf
Ngày tải lên :
09/08/2014, 09:20
... a single dose Gy× at 60min intervals 2.57 Gy×7 at 10min intervals Gy× at 30min intervals 2.57 Gy×7 at 5min intervals control 18 Gy as a single dose Gy× at 60min intervals 2.57 Gy×7 at 10min intervals ... fractions of 2.57 Gy with interfraction intervals of 10 min, (4) fractions Page of of Gy with interfraction intervals of 30 min, (5) fractions of 2.57 Gy with interfraction intervals of Assay Tumor ... University was grown in RPMI 1640 (Gibco BRL, USA) supplemented with 10% fetal bovine serum, 100 μg/ml streptomycin and 100 U/ml penicillin The cell line was incubated at 37°C in 5% CO until near-confluency,...
- 6
- 289
- 0
Báo cáo khoa học: "Postmastectomy irradiation in breast in breast cancer patients with T1-2 and 1-3 positive axillary lymph nodes: Is there a role for radiation therapy" ppsx
Ngày tải lên :
09/08/2014, 09:20
... above the seventh rib Any relapse involving the axillary lymph nodes, and/or other nodes in the infra or supraclavicular fossa or in the internal mammary chain was considered as a regional recurrence ... with to positive lymph nodes remains uncertain and is being examined in a randomized clinical trial” Many surgeons and radiation oncologist are not recommending PMRT to 1-3 axillary lymph node ... crude way of defining a potential indication for PMRT More information may come from other clinicopathologic parameters (e.g., capsule and lymphovascular invasion, malignancy grading, etc.) Moreover,...
- 8
- 357
- 0
Báo cáo khoa học: " Potentials of on-line repositioning based on implanted fiducial markers and electronic portal imaging in prostate cancer radiotherapy" docx
Ngày tải lên :
09/08/2014, 09:22
... performed on-line by repositioning the target according to the internal markers, moving the treatment couch manually To calculate the minimum required margin width around the clinical target ... the interobserver variability is low Therefore implanted markers and EPID based methods are used for targeting in radiotherapy of prostate cancer with increasing frequency Our results provide information ... precision is achieved by using intraprostatic markers Figure showing the mean in setup directions a box plot tion (bottom the box) errorand box) and horizontal horizontal line) in and totalLR, SIthe...
- 9
- 300
- 0
Báo cáo khoa học: " The TGF-β1 dynamics during radiation therapy and its correlation to symptomatic radiation pneumonitis in lung cancer patients" potx
Ngày tải lên :
09/08/2014, 10:20
... molecular events in developing radiation-induced complications in normal tissue [5,8,12] Several clinical reports have suggested a possible role of profibrogenic and proinflammatory cytokines in the modulation ... Profibrogenic cytokine TGF-β1 is the most extensively investigated among the various biological markers in radiation-induced injuries We observed that TGF-β1 decreased during RT and it began to increase ... pneumonitis in several reports [13,23] Especially Arpin et al reported covariation of proinflammatory cytokine (IL6) and anti-inflammatory cytokine (IL-10) levels during the first week of RT were independent...
- 9
- 271
- 0
Báo cáo khoa hoc:" Genetic variation in two conserved local Romanian pig breeds using type 1 DNA markers" pdf
Ngày tải lên :
09/08/2014, 18:21
... breed Their manner of breeding following the initial crossing is unknown, but is thought to have been uncontrolled The local breeders used inbreeding to improve and to maintain the superior traits ... with dominantly inherited obesity in humans [38,42] The inactivation of the MC4R gene in the mouse has resulted in a maturity onset obesity syndrome, demonstrating the role of this gene in regulation ... test for a major gene in pig breeding [9] A single point mutation in the calcium release channel gene, when present in the homozygous condition, is responsible for porcine stress syndrome (PSS,...
- 16
- 282
- 0
Báo cáo y học: "Period-2: a tumor suppressor gene in breast cancer" pdf
Ngày tải lên :
10/08/2014, 09:20
... whereas in wild-type mice the clock genes are induced rapidly, suggesting they may be involved in DNA damage response Furthermore, a number of cell cycle and checkpoint proteins were deregulated in ... plasmids containing the human Per or Cry genes as described above On each day following transfection cells were harvested in phosphate-buffered saline (PBS)/EDTA solution containing 0.1% trypsin and ... seeded in 12-well plates (3.8 cm2) in culture medium containing 0.35% low-melting agarose over a 0.7% agarose base layer and incubated for 12 days at 37ºC in a humidified 5% CO2 atmosphere in RPMI...
- 9
- 362
- 0
báo cáo khoa học: " Overexpression of Pim-1 in bladder cancer" pdf
Ngày tải lên :
10/08/2014, 10:20
... further classified into Noninvasive (Tis, Ta and T1) and invasive (≥T2) groups The data (Table 2) shows that the staining intensity of Pim-1 is increased in invasive bladder carcinoma samples (95%) ... illustrated Scoring and Statistical analyses The staining of Pim-1 was graded in each sample based on the intensity of the immunoreactivity in the cancer cells and was stratified as strong staining (3), ... (3), moderate staining (2), weak staining (1) and negative (0) Using these criteria, the immunostaining results were evaluated independently by XPM and BH The correlation of interobserver was...
- 7
- 222
- 0