1 failure of first line treatment

... boosted PI for first- line treatment of all children under three years of age or weighing less than 10 kilograms All recommended second -line regimens for children failing NNRTI-based first- line ART ... in Asia, it was part of the first- line regimen in 92% of children in southern Africa Ten percent of Asian and 3.3% of African children were on second -line ART at the time of data transfer Asian ... much higher In Asia, 15% of children in a Cambodian study and 37% of children in a Chinese study had viral loads of more than 1000 copies/ml after 12 months of first- line ART [11,12] An earlier...

Ngày tải lên: 20/06/2014, 08:20

... : A biregional survey and review of first- line treatment failure and second -line pediatric antiretroviral access and use in Asia and southern Africa Journal of the International AIDS Society ... AIDS (IeDEA) Southern Africa Paediatric Group: A biregional survey and review of first- line treatment failure and second -line paediatric antiretroviral access and use in Asia and southern Africa ... and Journal of the International AIDS Society 2011, 14:17 http://www.jiasociety.org/content/14/1/17 Page of Table First- and second -line antiretroviral therapy regimens...

Ngày tải lên: 20/06/2014, 08:20

... patient had a treatment- unrelated early death, and the other refused the treatment for reasons not related to toxicity during the course of the 2nd cycle Treatment administration of S-1 was delayed ... 1Department of Surgery, Division of Frontier Medical Science, Graduate School of Biomedical Science, Hiroshima University, Hiroshima, Japan and 2Department of Surgical Oncology, Graduate School of Medicine, ... current study were to retrospectively clarify the efficacy and toxicities of the docetaxel and S-1 combination as a first- line treatment for patients with advanced or recurrent gastric cancer and...

Ngày tải lên: 09/08/2014, 03:21

... with treatment failure after 24 months of ART Discussion This study, with a large cohort of children on ART, showed that first- line treatment remained effective in Isaakidis et al Journal of the ... other first- line cohort studies in resource-limited settings describing HIV-1 reverse transcriptase mutation patterns In future, standardized second -line regimens based on the type of first- line treatments ... months of first- line ART by December 2007 were eligible for this study All children ever started on ART, regardless of time on treatment, were included in the overall survival analysis of the...

Ngày tải lên: 20/06/2014, 08:20

... characteristic of imatinib treatment, such as rash, edema, and weight gain [19] Page of 10 The importance of adherence to imatinib in response to treatment is further illustrated by the results of a phase ... to imatinib [17] The AE profiles and tolerability of newer treatments are therefore important considerations for clinical practice in the first- line setting in terms of both efficacy and safety ... were also noted in smaller numbers of patients [25] In the DASISION trial, first- line dasatinib treatment resulted in fewer cases of rash compared with imatinib treatment (11% vs 17%), with grade...

Ngày tải lên: 10/08/2014, 22:21

... retention time (HRT) of 17 h (Ozer and Kasirga, 1995), (ii) to investigate the valorisation in wastewater treatment field of waste biomass of A niger and (iii) to verify the secretion of extracellular ... proposed bioaugmentation of indigenous bacteria; but it has not been performed and developed One of the explanations for this lack of interest could be the high concentration of required mixed liquor ... secretion of enzymes in its growth medium The aims of this research were (i) to assess the ability of A niger in removing chemical oxygen demand (COD) and proteins in raw wastewater under long sewer line...

Ngày tải lên: 05/09/2013, 09:08

... functionality of monocytes after treatment, we considered the upregulation of the expression of any one of these independent markers by more than 50% to be a gain of function In the 1.25 mg-group, 28% of ... Page of 11 The a priori level of significance was a p-value of < 0.05 Data was computed using JMP® software Results Safety Two out of the 33 enrolled patients were removed from the 1.25 mg arm of ... increases of monocytes (CD45 + CD14 + , 20 patients out of 24), NK cells, (CD3 - CD16 + CD56 + , 15 out of 24) and activated (CD38 + HLA-DR + ) CD8 T cells (17 out of 24) in absolute numbers per μl of...

Ngày tải lên: 18/06/2014, 16:20

... of alternative firstline ART was two months, with a range of 10 days to 28.1 months Of the patients on alternative first- line ART, 60.7% were male Average time on ART until switch to second -line ... http://www.jiasociety.org/content/13/1/31 Page of Table Reasons for discontinuation of standard first- line ART regimen Reason for discontinuation of standard first- line ART (d4T/3TC/NVP) Number of patients (male/female) ... probability of failure after one year on the first- line regimen was 1.6% (95% CI: 0.9-2.6) This retrospective cohort review shows that the Malawian standard first- line ART regimen of d4T/3TC/NVP...

Ngày tải lên: 20/06/2014, 08:20

... mean difficult choices in the allocation of treatment modalities Therefore, a basic knowledge of the state of the art of the diagnosis and treatment of spinal disorders is required, not only ... Fundamentals of Diagnosis and Treatment Norbert Boos · Max Aebi (Editors) Spinal Disorders Fundamentals of Diagnosis and Treatment With 274 Figures in 1290 Parts and 190 Tables Prof Dr Norbert ... specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks Duplication of this publication...

Ngày tải lên: 02/07/2014, 06:20

... NA sequences of the ORF2 canine LINE- 1 and the TVT -LINE The ORF2 of caine LINE- 1 has one open reading frame from 178 to 4002 nucleotide The DNA sequences of the TVT -LINE in TVT lines are compared ... one of the causes of oncogenesis in the TVT Discussion In this study, we determined the DNA sequences of the ORF2 for canine LINE- 1 element and those of the LINE- 1 integrated in c-myc gene of ... compared with those of canine LINE- 1 The underlined below the sequences shows the reverse complementary 416-bp sequences of TVT -LINE The ten direct repeats found in the TVT -LINE are marked by...

Ngày tải lên: 07/08/2014, 15:20

... outcome of the disease: type of hormonotherapy, type of chemotherapy, type of response achieved by treatment [5-12] The impact of some factors remains debatable, such the duration of treatment ... versus liver); number of metastatic sites (single versus multiple); type of first- line chemotherapy (anthracycline- and/or taxane-containing regimen versus other); previous line of hormonotherapy ... the beginning of first line chemotherapy treatment to the date of progressive disease or death Metastatic survival is defined as the time from the diagnosis of a metastasis to date of death or...

Ngày tải lên: 08/08/2014, 17:20

... abdomen ultrasound depending on those used at baseline Time to progression (TTP) was calculated from the date of treatment start to the date of first- documented progression Overall survival (OS) ... positive cells on the total number of tumor cells A value of 11% of positive cells, corresponding to the mean value of p53 expressing tumor cells, was used as cut-off to distinguish high and low ... 10% of the tumor cells (0); weak staining in part of the membrane in more than 10% of the tumor cells (1+); complete staining of the membrane with weak or moderate intensity in more than 10% of...

Ngày tải lên: 10/08/2014, 10:21

... Table shows the course of disease concerning radiological lesions (means) in the first year of treatment Most bone lesions of the extremities were localized in the metaphyses of the long bones close ... 2Institute of Radiology, Department of Pediatric Radiology, University of Würzburg, Josef Schneider Straße 2, 97080 Würzburg, Germany 3University of Jena, Institute of Radiology, Department of Pediatric ... available Course of disease Treatment All patients were treated with naproxen (15 mg/kg/day) for 12 months starting shortly after biopsy Naproxen was well tolerated during the first year of treatment...

Ngày tải lên: 12/08/2014, 12:20

... out of the bottle If an infant (assuming kg of weight) ingests about 700 ml of breast milk a day[18], at a treatment concentration of 0.1% this would represent an intake of SDS 0.7 g If 90% of ... Influence of the heat treatment of human milk on some of its protective constituents J Pediatr 1977, 90:29-35 Papathakis PC, Rollins NC: Adequacy of feeding recommendations for infants of HIV-infected ... because: (1) of the time it may require to express milk, and (2) of the added cost of the final device if a mechanical milk pumping device would be required An economic assessment of this milk treatment...

Ngày tải lên: 13/08/2014, 09:21

... Education 1991, 60:427-440 Madoff J: Islands of Success in the Midst of Inequality: the situation of AIDS care for women of color Dissertation, Mailman School of Public Health of Columbia University; ... variety of methods, including lists of agencies maintained by the County Department of Health, brochures of existing services and telephone books A total of 51 agencies were identified Directors of ... than the existence of such islands of success was the relative scarcity of such holistic care, due, in large part, to the relative scarcity of some components of the package of services, and typically...

Ngày tải lên: 13/08/2014, 16:21

... Sixty-one percent of the subjects had been accused of a single offense, 31% of two offenses and 8% of three or more offenses The nature of the offenses was: 48% property offenses, 21% offenses against ... 7% sex offenses, and 3% other types of offenses Fortyone percent of the subjects had a history of registration by the police Table demonstrates the concern of the CPB worker by domains of the ... sensitivity of 81% and a specificity of 69% (Figure 2) For the Y&P-index, the AUC reached a moderate level of 0.79 (95% CI: 0.67 - 0.91, p < 0.0001) The optimal cut-off of 13.5 had a sensitivity of 77%...

Ngày tải lên: 13/08/2014, 18:22

... months or at time of switch to second line regimens 2.2.2.5 Rresearch procedures Recruiment of patients at base line (T1) At the the time of commencement of first- line ART, in the last of counselling ... resistance prevention at 12 months of first line ART 2.3 Percentage of patients with HIV drug resistance who receiving first line ART in OPC at base line and at 12 months of ART was low Specify: - 3.5% ... ending point of the study – 12 months after ART 1st line (T2) After 12 months of 1st line ART, 415 patients maintained the st line ART and no patient was officially transferred to nd line ART After...

Ngày tải lên: 04/10/2014, 13:22

... of the teacher of English to speakers of Other Languages Orlando FL, March 11-15 35 Riazi, A M (2003), What textbook evaluation schemes tell us? , A study of the textbook evaluation schemes of ... Rationale……………………………………………………………………… Aims of the study………………………………………… Research questions…………………………………………… Significance of the study……………………………… Methods of the study…………………………………………………………… Scope of the study……………………………………………………………… ... Chapter 2: An overview of the textbook and current Situation of using textbook at HUI 14 2.1 Current situation of using textbook…………………………………………… 14 2.1.1 Brief introduction of HUI……………………………………………………...

Ngày tải lên: 10/08/2015, 19:50

... strength of ply X’ longitudinal compressive strength of ply Y transverse tensile strength of ply Y’ transverse compressive strength of ply ! ! ! ! ! ! ! ! !xii List of Acronyms List of Acronyms ... resulting in premature failure of the laminates The detrimental !viii Summary effect of off-axis loading and the introduction of an open-hole in the laminates for each of the three loading angles ... displacement of 0.45 mm ! ! !xxi List of Tables List of Tables Table Cruciform specimen geometries Table Summary of the six test cases in the current study Table Specifications of unnotched cruciform...

Ngày tải lên: 09/09/2015, 08:18

... resistance of femur fractures (29) and also the torsional strength of distracted rabbit tibiae(30)Nilsson et al (31) compared the influences of heparin, dextrane and HBOT in preventing soft and ... in periosteum of CPCBB specimens could have limited the effects of HBOT on these groups From this point of view, these findings could also suggest that the successful interaction of a bone graft ... J Oral Maxillofac Surg 2010 Jul;68(7):1642-5 Hislop WS, Finlay PM, Moos KF A preliminary study into the uses of anorganic bone in oral and maxillofacial surgery Br J Oral Maxillofac Surg 1993;...

Ngày tải lên: 25/10/2012, 11:15