1 b cell acute lymphoblastic leukemia all

... cyclophosphamide/vincristine/doxorubicin/ dexamethasone; IHC: immunohistochemistry; pre-B -cell ALL: precursor B -cell acute lymphoblastic leukemia Page of major contributor to the Discussion section NA was involved ... precursor T cell lymphoblastic leukemia/ lymphoma with cholestatic jaundice: case report J Hematol Oncol 2009, 2:12 Alvaro F, Jain M, Morris LL, Rice MS: Childhood acute lymphoblastic leukemia presenting ... function test results in acute leukemia Ann Pharmacother 2005, 39:1752-1754 doi:10.1186/1752-1947-5-269 Cite this article as: Siddique et al.: Precursor B -cell acute lymphoblastic leukemia presenting...

Ngày tải lên: 10/08/2014, 23:21

... del(9)(q34.11q34.13) in patients with T -cell acute lymphoblastic leukemia (T -ALL) [4] It has also been reported in a single case of acute myeloid leukemia (AML) [5] SETNUP214 positive T -ALL patients exhibited ... myeloid cell origin to detect SET-NUP214 positive examples A T -ALL cell line LOUCY (1/43 T cell lines tested) and an AML cell line MEGAL (1/53 myeloid cell lines tested) were the only cell lines ... positive cell line LOUCY than in six other T -ALL cell lines tested (data not shown) HOXA9 expression levels were also high in cell line MEGAL, but not above many SET-NUP214 negative AML cell lines...

Ngày tải lên: 10/08/2014, 22:20

... apoptosis in human T -cell acute lymphoblastic leukemia (T -ALL) cell lines (Jurkat, Molt-4) Additionally, global gene expression profiling revealed that BCL11B siRNA-mediated cell apoptosis may ... and treatment of childhood T-lineage acute lymphoblastic leukemia Blood 1998, 91:735-746 Morris JC, Waldmann TA, Janik JE: Receptor-Directed Therapy of T -Cell Leukemias and Lymphomas J Immunotoxicol ... patients with T -ALL, to clarify the role of BCL11B in T -cell malignancies Methods Samples Nine newly diagnosed T -ALL patients (male, 6-28 years old; median age, 20 years; white blood cell count (WBC),...

Ngày tải lên: 10/08/2014, 22:21

Ngày tải lên: 14/11/2016, 06:05

... Study Group for Adult Acute Lymphoblastic Leukemia: Clinical significance of minimal residual disease quantification in adult patients with standard-risk acute lymphoblastic leukemia Blood 2006, ... TEL-AML1 as MRD in CD 10 positive ALL is needed to determine how to best integrate TEL-AML1 testing into routine patient care Abbreviations ALL: Acute lymphoblastic leukemia; CD: cluster differentiation; ... childhood ALL This translocation has been recognized as the most common chromosomal aberration in childhood ALL [2-4] All (95–100%) of TEL-AML1 positive ALL patients found to has a consistent cell...

Ngày tải lên: 10/08/2014, 22:20

... Etiology of ALL Chapter Model for Identifying the Etiology of Acute Lymphoblastic Leukemia in Children Juan Manuel Mejía-Aranguré Chapter Infectious Etiology of Childhood Acute Lymphoblastic Leukemia, ... with acute lymphoblastic leukemias in Mexico City Leukemia & lymphoma 2009; 50(8): 1352–60 [32] Chuk MK, McIntyre E, Small D, Brown P Discordance of MLL-rearranged (MLL-R) infant acute lymphoblastic ... Mejía-Aranguré Contents Chapter 13 Acute Lymphoblastic Leukemia (ALL) Philadelphia Positive (Ph1) (Incidence Classifications, Prognostic Factor in ALL Principles of ALL Therapy) 297 Alicia Enrico...

Ngày tải lên: 17/03/2014, 12:20

... and cell derivation of B cell chronic lymphocytic leukemia Curr Top Microbiol Immunol 2005, 294:31-49 Caligaris-Cappio F, Ghia P: The normal counterpart to the chronic lymphocytic leukemia B cell ... other neoplastic B-cells [62,63] For this reason CLL is nowadays believed to derive from subsets of marginal zone memory B-cells that have undergone either a T -cell dependent or Tcell independent ... ZAP-70 ZAP-70 encodes for T cell specific zeta-associated protein70 and has been initially identified in T cells as a protein tyrosine kinase that plays a critical role in T -cell- receptor signaling...

Ngày tải lên: 18/06/2014, 15:20

... childhood acute lymphoblastic leukemia (ALL) in developed countries are about 80%, the survival rates in developing countries are often less than 35% In our previous study the overall even-free ... childhood acute lymphoblastic leukemia: experience in Chennai J Trop Pediatr 1999, 45:367-70 Metzger ML, Howard SC, Fu LC, Pena A, Stefan R, Hancock ML, et al.: Outcome of childhood acute lymphoblastic ... HRQOL in ALL patients on treatment [19,25] In contrast, studies on survivors of ALL found that psychosocial health was lower than physical health [27,28] Although survivors of ALL were generally...

Ngày tải lên: 18/06/2014, 19:20

... (median and inter quartile range) All CSHQ score 7 years ALL (n = 17) Norm* (n = 1507) p ALL (n = 6) Norm* (n = 174) p ALL (n = 6) Norm* (n = 315) p ALL (n = 5) Norm* (n = 1018) ... sleep and QoL, and on factors affecting sleep in pediatric ALL and in children with cancer in general Abbreviations ALL: Acute lymphoblastic leukemia; CHQ: Child Health Questionnaire; CSHQ: Children’s ... C, Glaser A: HRQOL implications of treatment with dexamethasone for children with acute lymphoblastic leukemia (ALL) Pediatr Blood Cancer 2006, 46(1):35-39 37 Gregory AM, Eley TC: Sleep problems,...

Ngày tải lên: 20/06/2014, 15:20

... childhood acute lymphoblastic leukemia (ALL) in developed countries are about 80%, the survival rates in developing countries are often less than 35% In our previous study the overall even-free ... childhood acute lymphoblastic leukemia: experience in Chennai J Trop Pediatr 1999, 45:367-70 Metzger ML, Howard SC, Fu LC, Pena A, Stefan R, Hancock ML, et al.: Outcome of childhood acute lymphoblastic ... HRQOL in ALL patients on treatment [19,25] In contrast, studies on survivors of ALL found that psychosocial health was lower than physical health [27,28] Although survivors of ALL were generally...

Ngày tải lên: 20/06/2014, 16:20

... chemotherapy, allogeneic or autologous stem cell transplantation as post-remission treatment for adult patients with high-risk acute lymphoblastic leukemia Final results of the PETHEMA ALL- 93 Trial ... lymphocytes from acute lymphoblastic leukemia (ALL) patients as well as to take them as predictors for radiation toxicity Methods: Peripheral blood lymphocytes were isolated from 26 ALL patients ... nonspecific dsDNA-binding dye PCR methods previously used [16] Besides, we taken the acute lymphoblastic leukemia (ALL) patients undergoging total body irradiation (TBI) precondionting as human beings...

Ngày tải lên: 09/08/2014, 09:21

... 2,8-20,7 0,9-10,4 ALL treatment (years) Median Time from completion of ALL treatment (years) Median 7,8 12,7 6,1 0,5-4,3 1,8-4,3 0,5-3,4 3,2 2,7 3,2 ALL - acute lymphoblastic leukemia; CRT - cranial ... hypertension and other cardiovascular diseases [2] Survivors of pediatric acute lymphoblastic leukemia (ALL) are at substantially increased risk of developing obesity [3-5] The most common explanations ... ALL diagnosis and after ALL treatment was found No statistically significant correlation between variants of the tested genes and intensity of ALL treatment, CRT and overweight status after ALL...

Ngày tải lên: 10/08/2014, 10:21

... blast cells consistent with acute leukemia Peripheral blood flow cytometry on immunophenotyping with five-color cytomics (fc500 Beckman Coulter flow cytometer) showed this population of cells ... very prominent, so immunophenotypic results were consistent with precursor-T -acute lymphoblastic leukemia (Pre-T -ALL) Bone marrow cytogenetics revealed a normal karyotype and negative Philadelphia ... myelosuppression [10] All alkylating agents are considered to carry a five to ten percent mutagenic risk potential for development of myeloid leukemia, but not for lymphoblastic leukemia TMZ is a...

Ngày tải lên: 11/08/2014, 03:21

... blast cells consistent with acute leukemia Peripheral blood flow cytometry on immunophenotyping with five-color cytomics (fc500 Beckman Coulter flow cytometer) showed this population of cells ... very prominent, so immunophenotypic results were consistent with precursor-T -acute lymphoblastic leukemia (Pre-T -ALL) Bone marrow cytogenetics revealed a normal karyotype and negative Philadelphia ... myelosuppression [10] All alkylating agents are considered to carry a five to ten percent mutagenic risk potential for development of myeloid leukemia, but not for lymphoblastic leukemia TMZ is a...

Ngày tải lên: 11/08/2014, 07:20

... children with acute lymphoblastic leukemia Leukemia 2001, 15:74-79 Schmiegelow K, Forestier E, Hellebostad M, et al: Long-term results of NOPHO ALL- 92 and ALL- 2000 studies of childhood acute lymphoblastic ... risk acute lymphoblastic leukemia predicts risk of relapse Leukemia 2010, 24:715-720 35 Pui CH, Boyett JM, Relling MV, et al: Sex differences in prognosis for children with acute lymphoblastic leukemia ... of relapse for some children with acute lymphoblastic leukemia J Clin Oncol 2003, 21:1332-1339 Cunningham L, Aplenc R: Pharmacogenetics of acute lymphoblastic leukemia treatment response Expert...

Ngày tải lên: 13/08/2014, 13:20

... relapses are shown in the figure 96 x LIST OF ABBREVIATION ALL Acute Lymphoblastic Leukemia AML Acute Myeloid Leukemia CCR Continuous Complete Remission DT Decision Tree FDR False ... inflammatory response, and cell- to -cell signaling and interaction 51 Figure 4.4: The second top biological network, inflammatory response, cell death, and cell- to -cell signaling and interaction ... her support i SUMMARY Childhood acute lymphoblastic leukemia (ALL) is the most common type of cancer in children Contemporary management of patients with childhood ALL is based on the concept of...

Ngày tải lên: 10/09/2015, 15:50

... ATRA: all- trans retinoid acid; APL: acute promyelocytic leukemia; Aur: Aurora; PARP: poly ADP ribose polymerase; PML/RARα: promyelocytic leukemiaretinoid acid receptor α; AML: acute myeloid leukemia; ... μg/ml), cells were visualized using a microscope (1000 ×, Olympus) Cell growth assay Cell proliferation was assessed by MTT assay NB4-R2 cells were plated in 96-well plates at 2.5 × 104 cells/ml ... Aurora suppresses Akt-1 activation and induces apoptotic cell death in all- trans retinoid acid-resistant acute promyelocytic leukemia cells Journal of Translational Medicine 2011 9:74 Submit...

Ngày tải lên: 18/06/2014, 19:20

... ATRA: all- trans retinoid acid; APL: acute promyelocytic leukemia; Aur: Aurora; PARP: poly ADP ribose polymerase; PML/RARα: promyelocytic leukemiaretinoid acid receptor α; AML: acute myeloid leukemia; ... μg/ml), cells were visualized using a microscope (1000 ×, Olympus) Cell growth assay Cell proliferation was assessed by MTT assay NB4-R2 cells were plated in 96-well plates at 2.5 × 104 cells/ml ... Aurora suppresses Akt-1 activation and induces apoptotic cell death in all- trans retinoid acid-resistant acute promyelocytic leukemia cells Journal of Translational Medicine 2011 9:74 Submit...

Ngày tải lên: 20/06/2014, 03:20

... digestion pattern from patient alleles from AML cell DNA after transplantation; Lane = digestion pattern from donor cell alleles post-SCT hematopoietic cells and the donor’s cells were the same, revealing ... basophilic and/or mastocytic, cell phenotypes are uncommon and they account for only 4-5% of all cases of acute nonlymphocytic leukemia [34,35] Although acute basophilic leukemia (ABL) has been long ... of a secondary AML developing from donor-derived cells in a breast cancer patient who underwent allogeneic stem cell transplantation Donor cell leukemia is a rare although well-recognized disease...

Ngày tải lên: 10/08/2014, 21:23

... G, Hallek M, Hiddemann W, Kolb HJ: Long-term survival in refractory acute myeloid leukemia after sequential treatment with chemotherapy and reducedintensity conditioning for allogeneic stem cell ... reduced-intensity conditioning for allogeneic 15 16 17 18 19 20 21 22 stem -cell transplantation, and prophylactic donor lymphocyte transfusion in high-risk acute myeloid leukemia and myelodysplastic ... efficacy of an intermediate intensity conditioning regimen for allogeneic stem cell transplantation in patients with high-risk acute myeloid leukemia in first complete remission Bone Marrow Transplant...

Ngày tải lên: 10/08/2014, 22:21