... characterize the polymorphic behavior of an organic compound API over a temperature range of hundreds of degrees This allows the simultaneous measurements of thermochemical and thermophysical ... (see Figures and 9) The lack of any additional peaks in the XRPD patterns would imply the presence of an Figure DSC of atypical anhydrous Form I (sample 11) amorphous material and/or an impurity ... real time detection of the volatiles over the duration of the thermogravimetric analysis Simultaneously, a second split was also used to direct another small fraction of the evolved gases to...
Ngày tải lên: 14/02/2014, 03:20
... from the other Disappearance of some resonances without the obvious appearance of new signals suggests the presence of an intermediate rateexchanging equilibrium between the resonances of the ... disappearance of specific resonances without the concomitant appearance of other signals in other parts of the spectrum This result could be a consequence of the paramagnetic properties of Fe(II), ... rather than with specific binding Aggregation seems to initiate around the first helix Titration of CyaY with lanthanides ) the effect of europium and ytterbium Lanthanides were used to enhance the...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: Coordination chemistry of iron(III)±porphyrin±antibody complexes In¯uence on the peroxidase activity of the axial coordination of an imidazole on the iron atom ppt
... the antibody and particularly to appreciate the size of the cavity left around the iron atom and which kind of ligands it can accommodate; second, to measure the in¯uence of an axial ligand of ... (Table 1) The binding of the ®rst CN± ligand to the iron was thus more easy in the hydrophobic binding pocket of the antibody than the binding of the second one, most probably because of the steric ... bound to the iron, the steric hindrance due to the substituent could be balanced by a distortion of the porphyrin ring and a shift of the iron atom outside the plane of the porphyrin Binding of imidazole...
Ngày tải lên: 21/02/2014, 03:20
Báo cáo khoa học: The catalytic mechanism of dye-decolorizing peroxidase DyP may require the swinging movement of an aspartic acid residue potx
... H2O2 and CN, the position of the carbon atom of CN bound to the heme iron mimics the position of the proximal oxygen of H2O2 bound to the heme iron during compound I formation Therefore, the carbon ... each structure The distance between the CN carbon atom and the iron atom of heme is ˚ 2.05 A On the right, the relevant four residues are rotated by 60° to assist in an understanding of differences ... achieved with the hang- Fig The swinging mechanism of Asp171 (A) Interpretation of distances between Asp171 and a virtual proximal oxygen of H2O2 in the native and D171N-CN The native and D171N-CN...
Ngày tải lên: 06/03/2014, 00:20
the accidental death of an anarchist
... political amalgamation of lies aimed at hiding the truth behind the anarchist's death There were many themes presented in ADOA including that of the abuse of power by the authoritarian This occurs when ... By breaking down the fourth wall, the audience becomes co-conspirators, and part of the political conspiracy Through the Maniac's exaggerated and comic view of the court system, the responder also ... of the truth i.e the Italian police and the corrupt nature of society This is shown when the Maniac ridicules the police by burning and throwing out documents, mocking the way the police destroy...
Ngày tải lên: 21/03/2014, 22:52
Báo cáo khoa học: The role of residues R97 and Y331 in modulating the pH optimum of an insect b-glycosidase of family 1 pdf
... deglycosylation) of the hydrolysis of MUbglc by the mutant enzymes is rate-limiting, no hypothesis on the effect of R97 and Y331 on the rate constant of each step can be advanced ể FEBS 2003 Mechanism of ... As the pKa values of the catalytic residues determine the pH optima, the ionization constants (pKa) of the catalytic glutamates (E187 and E399) in the ES complex and in the free enzyme (E) of ... b-glucosidase affected the rate constant of the glycosylation step and also changed the enzyme pH optimum [14] Despite that, the effect of the tyrosine on the pKa values of the b-glycosidase catalytic...
Ngày tải lên: 23/03/2014, 15:21
hack the stack - using snort & ethereal to master the 8 layers of an insecure network
... to another Port 20 is used for the data stream, and transfers the data between the client and the server Port 21 is the control stream, and is used to pass commands between the client and the ... attacks, the bulk of the work of a social engineering attack is doing the reconnaissance and laying the groundwork .The attack itself usually takes on one of the following angles: ■ Diffusion of Responsibility ... user and privileged mode As you move toward the outer bounds of the model, the numbers increase and the level of trust decreases Another advancement in computer security was in the development of...
Ngày tải lên: 25/03/2014, 11:19
numerical analysis of the spectral response of an nsom measurement
... gives the magnitude of the energy flow and its direction Figure shows the sum of the energy density stored in the electric and magnetic field and the magnitude of the Poynting vector at the center of ... respectively The variance of the permittivity shown in Fig is reflected in both the near and far-fields and the peaks from the PEC model are dra- Numerical analysis of the spectral response of an NSOM ... is that the E field is orthogonal to the H field and scaled by η, the impedance of the medium This allows easy calculation of the radiated power The far-field response has both an angular and spectral...
Ngày tải lên: 06/05/2014, 08:58
university of texas press thelma & louise live the cultural afterlife of an american film nov 2007
... take advantage of the sweep of the American West, situating the personal development of the characters into the visual iconography of the American cinema and history In Thelma & Louise: The Last ... availability, the absence of civilization, and so hides the histories of the West in favor of the familiar fantasies of the West as an unoccupied place of self-creation for Anglo tourists (like their ... image of an empty two-lane blacktop road, emerging from the bottom center of the poster and leading toward an image of Monument Valley, a horizon of mesas and rocks across the lowest quarter of the...
Ngày tải lên: 11/06/2014, 13:58
university of texas press the teotihuacan trinity the sociopolitical structure of an ancient mesoamerican city dec 2007
... Teotihuacan and the appearance of the Teotihuacan state outside the Valley of Mexico This suggests that the manufacture and trade of obsidian were at least partially responsible for an increased ... Furthermore, these courtyards work in tandem with another feature of the avenue The walk is not only a directional one, but a vertical climb as well The southern section of the Avenue of the ... most of the construction at Teotihuacan concentrated on the grand pyramids along the main avenue, but during the end of the Miccaotli and the beginning of the Tlamimilolpa periods (a.d 200–250) an...
Ngày tải lên: 11/06/2014, 15:57
kidd - 1808 - remarks and experiments on the different parts of brewing
Ngày tải lên: 12/06/2014, 11:36
Báo cáo hóa học: " Development and application of a biomarker assay for determining the pharmacodynamic activity of an antagonist candidate biotherapeutic antibody to IL21R in whole blood" pptx
... performed all the studies on human samples reported here, analyzed the data and co-wrote the manuscript SJ and AAW performed all the pilot studies in humans and monkeys that identified the candidate ... data analysis and review and participated in the drafting of the manuscript DY co-led the Ab-01 team and was responsible for studies related to the characterization of the biological properties of ... observed in both humans and monkeys The presence of IL21R on the top gene list for monkeys and not for humans reflects a higher relative ranking in monkeys due to the lack of IFNγ and CD19 data in...
Ngày tải lên: 18/06/2014, 16:20
báo cáo sinh học:" Empowering the people: Development of an HIV peer education model for low literacy rural communities in India" pdf
... KK, VC and DS participated in the initial concept, the design of the study and the development of the IEC materials KVR assisted in data analysis and drafted the manuscript MR designed the monitoring ... formed by the OW of READ [10]) performed street theatre with acts that illustrated the modes of HIV transmission, the impact of the disease on the body's defences of the infected person, and ultimately ... to loans for micro-enterprise development) Monitoring and evaluation The evaluation of PEPP involved the collection and analysis of both quantitative and qualitative data Triangulation of data...
Ngày tải lên: 18/06/2014, 17:20
báo cáo sinh học:" Understanding the ‘four directions of travel’: qualitative research into the factors affecting recruitment and retention of doctors in rural Vietnam" doc
... Acknowledgements The study was designed and financed by the World Bank, and it was executed in collaboration with the Ministry of Health, Hanoi, by Oxford Policy Management and the Hanoi School of Public ... stable than in private practice They also identified better management and better professional ethics as factors: the lack of quality assurance and the focus on profit in the private sector has an ... is the main cadre of health worker providing clinical and preventive care, and the one with the greatest overall shortages and imbalances between remote and urban areas The master plan for human...
Ngày tải lên: 18/06/2014, 17:20
báo cáo hóa học:" New quality and quantity indices in science (NewQIS): the study protocol of an international project" docx
... is obvious that the policy for the allocation of research grants could benefit from an increase in 1) objectivity and 2) transparency This is due to the fact that non-transparent and questionable ... Ltd ence, specific organs, diseases or other phenomena 2) countries 3) publication dates 4) authors 5) affiliations depending on the focus of the study The data can then be transferred to visualisation ... asthma, the first being published in the year 1968 [14] These studies were published by 52 countries The US, Japan and the UK were the most productive countries, participating in 55.8% of all...
Ngày tải lên: 20/06/2014, 00:20
báo cáo hóa học:" Difficulty in diagnosing the pathological nature of an acute fracture of the clavicle: a case report" ppt
... conceived the idea and wrote the paper SA and SM analysed the notes and contributed to the discussion CBH was responsible for editing and approving the final manuscript All authors read and approved the ... (CT) scan of the thorax, abdomen and pelvis revealed a right renal tumour with metastases to the lungs, liver and bone The bone metastases were to the left clavicle and the right ilium A further ... investigations, and may include further imaging of the clavicle with cone views and upper rib radiographs or a CT scan to adequately delineate the fracture and the quality of the surrounding...
Ngày tải lên: 20/06/2014, 01:20
The Four Pillars of Investing: Lessons for Building a Winning Portfolio_2 ppt
... History of Interest Rates.) The tradeoff between the variability of bill payouts and the interestrate risk of consols reverses during the twentieth century With the abandonment of the gold standard ... inflation) with the otherwise ultrasafe consols On the other hand, the Englishman in the late Victorian era lived in, what seemed at the time, the height of stability and permanence With such ... decrease over time The stockholder, on the other hand, balanced the prospect of modest dividend growth versus the much higher risk of stocks The abandonment of the gold standard turned all that...
Ngày tải lên: 20/06/2014, 20:20
The Four Pillars of Investing: Lessons for Building a Winning Portfolio_3 potx
... state of affairs as normal, certain, and permanent, except in the direction of further improvement, and any deviation from it as aberrant, scandalous, and avoidable The projects and politics of ... years at an 8% DR The total present value of the mine—in effect, its “true value”—is the sum of all of the future dividends, discounted to the present This is the sum at the bottom of the table: ... a portfolio of value stocks is the equivalent of wearing a Nehru jacket over a pair of bell-bottom trousers 38 The Four Pillars of Investing The data on the performance of value and growth stocks...
Ngày tải lên: 20/06/2014, 20:20
The Four Pillars of Investing: Lessons for Building a Winning Portfolio_4 pdf
... reliable than that of the car manufacturer—people will need to buy food no matter what the condition of the economy or their employment On the other hand, the earnings and dividends of auto manufacturers ... statistical study of financial assets The importance of his generosity and research cannot be overstated He was directly responsible for the collection and analysis of most of the nation’s stock and bond ... fatal case of chimpanzee syndrome The years 1966–1967 were mediocre for Manhattan and in 1968, the patient crashed In the first half of the year, Manhattan lost 6.6% of its value while the market...
Ngày tải lên: 20/06/2014, 20:20
The Four Pillars of Investing: Lessons for Building a Winning Portfolio_5 docx
... Obviously, the magnitude of impact costs depends on the size of the fund, the size of the company, and the total amount transacted As a first approximation, assume that it is equal to the spread The four ... surveillance apparatus, the chances of pulling this off even once without winding up a guest of the state grow dimmer each year Put another way, the simple fact that there are so many talented analysts ... a mix of 60% S&P 500 and 40% Lehman Bond Index As you can see, more than 90% of these plans underperformed the 60/40 indexed mix Discouraged by this failure of active management, these plans are...
Ngày tải lên: 20/06/2014, 20:20