... roles of ANGPTL2 and ANGPTL6 ⁄ AGF in obesity and related metabolic diseases, and discuss whether these ANGPTLs could be targets for the prevention and treatment of these conditions Suppression of ... Induction Fig Schematic diagram showing the roles of ANGPTL2 and ANGPTL6 ⁄ AGF in obesity and related metabolic diseases The expression of ANGPTL2 and ANGPTL6 ⁄ AGF is induced in obese conditions ... 2992–3002 Handschin C & Spiegelman BM (2008) The role of exercise and PGC1a in inflammation and chronic disease Nature 454, 463–469 Reaven GM (2005) The insulin resistance syndrome: definition and dietary...
Ngày tải lên: 14/02/2014, 22:20
... food preparation and Beyond the Fundamentals: Healthy and Safe Environments – Recognizing & Preventing Infectious Diseases pg 16 of 16 cleaning and sanitation of the environment and toys in the ... nessPrev_0506.pdf Sample Activities Symptoms of Illness Activity Hand washing Activity Infectious Disease Policy Activity Handouts for Participants Handout B Handout C Hand washing Checklist California Child ... and Safe Environments – Recognizing & Preventing Infectious Diseases pg of 16 Sample Activity Hand Washing Activity Materials: Sink with soap and paper towels Cornstarch, glitter, cinnamon, and...
Ngày tải lên: 22/03/2014, 10:20
báo cáo hóa học:" Research Article Improving the Performance of Bus Platforms by Means of Segmentation and Optimized Resource Allocation" ppt
... described in [8] By a reasonable organization of the hardware components and of the bus segments, one can increase the degree of parallelism of data transfers and in this way possibly improve the overall ... number of clock “ticks”) On the other hand, each extra segment means a new switch for allowing the connectivity of the respective segment to the rest of the platform A balance between parallelism and ... solutions The proposed heuristics start with a random initial deviceto-segments allocation set by: (i) InitRandomly Random initial order of devices, and randomly set segment borders (code not shown)...
Ngày tải lên: 21/06/2014, 20:20
Báo cáo khoa học: "Evapotranspiration measurements in a Mediterranean forest stand by means of ecophysiological and microclimatic techniques" ppsx
... coefficient of 0.88 beginning of the season, the predawn potential was about -0.5 MPa water for both sprouts and standards and it reached minimum values (-2.6, -2.8 MPa for sprouts and standards, ... consisted of measuring in the field the water uptake of sampled trees, which represented the averages of the size classes A plastic tank was attached around the stem and filled with water The bark and ... adding a blue dye to the water and counting with a microscope the number and area of vessels filled by the solution The relationship between the real sap velocity ( Vs) and the heat pulse velocity...
Ngày tải lên: 09/08/2014, 02:21
scala how to make best use of functions and objects
... languages, through its rich and flexible type system, its sparse and clean syntax, and its marriage of functional and object paradigms.” - Charles Nutter, creator of JRuby “I can honestly say ... as capable of being a "replacement for Java" as Scala, and the momentum behind Scala is now unquestionable While Scala is not a dynamic language, it has many of the characteristics of popular ... Psychology of Programming Interest Group Conference, pages 174-187, Limerick, Ireland, 2009 24 Part 2: The Scala Design 25 The Scala design Scala strives for the tightest possible integration of OOP and...
Ngày tải lên: 24/10/2014, 13:47
tudies of common variations in two candidate genes of dyslipidemia and coronary artery disease
... STUDIES OF COMMON VARIATIONS IN TWO CANDIDATE GENES OF DYSLIPIDEMIA AND CORONARY ARTERY DISEASE HE XUELIAN (BACHELOR OF MEDICINE) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY ... complex diseases vary in severity of symptoms, age of onset, and even in their etiological mechanisms Finally, an important feature of complex diseases is that the contribution of each candidate ... carried out and should greatly advance our understanding of the genetic basis of common diseases and complex traits 2.2.4.2.3 Association tests To observe the association of genotypes with disease...
Ngày tải lên: 14/09/2015, 09:00
Epigenetic potential of histone deacetylase inhibitors in treating fibroproliferative diseases and preventing peri implantational fibrosis
... hyperproliferation of fibroblasts/myofibroblasts, excessive production and deposition of extracellular matrix and chronic inflammation The hallmark of fibroproliferative diseases is the excessive deposition of ... the proliferation of the endothelial cells and worsen the occlusion of the microvessels and hypoxia Concentrations of VEGF and TGFβ1 are significantly increased in culture medium of keloid fibroblasts ... M344 and SAHA) The antifibrotic effect of SAHA was fully characterized on normal fibroblasts of lung and skin, and pathological fibroblasts of idiopathic pulmonary fibrosis, hypertrophic scar and...
Ngày tải lên: 12/09/2015, 10:42
Báo cáo y học: "Association of the T+294C polymorphism in PPAR δ with low HDL cholesterol and coronary heart disease risk in women"
... Treatment of obese rhesus monkeys with GW 501516, a selective PPARδ agonist, led to a significant improvement of metabolic traits characterized by a rise of HDL and lowering of LDL, triglycerides, and ... N, Ballantyne CM, Gotto AM, Marian AJ Effects of PPARα, γ and δ haplotypes on plasma levels of lipids and progression of coronary atherosclerosis and response to statin therapy in the lipoprotein ... gene counting and compared using the ²אtest The data was analysed using SPSS 12.0 software The association between the +294T/C polymorphism and serum lipids, coronary heart disease, and body mass...
Ngày tải lên: 31/10/2012, 17:03
Báo cáo y học: "Incidence of Ocular Zoonoses referred to the Inflammatory and Autoimmune Ocular Diseases Service of the University of Parma - Italy"
... after a combination of medical treatment and surgery, with a final visual acuity of 40% in the affected eye [1] The only case of Lyme disease affected a 31 year-old farmer and his ocular manifestations ... Figure 1: Geographical location of the province of Parma (Italy) References Mora P, Vecchi M, Barbera L, Toscani M, Orsoni JG Use of systemic cyclosporin A in a case of severe Toxocara uveitis J...
Ngày tải lên: 03/11/2012, 11:11
Tài liệu Báo cáo khoa học: TEC family kinases in health and disease – loss-of-function of BTK and ITK and the gain-of-function fusions ITK–SYK and BTK–SYK pptx
... also identify individuals with mild disease, thereby providing the missing data The phenotype of XLA and the potential of BTK and ITK inhibitors The outcome of defective BTK signaling in humans ... the expression of ITK is extremely low and often undetectable in immunoblot analysis The activation of CD4+ cells, however, dramatically induces transcription of the ITK gene and is key for the ... family of cytoplasmic enzymes that are important for several aspects of leukocyte biology Both loss- and gain -of- function mutations in humans have been instrumental in our understanding of their...
Ngày tải lên: 14/02/2014, 18:20
Tài liệu Báo cáo khoa học: Proteomic analysis of dopamine and a-synuclein interplay in a cellular model of Parkinson’s disease pathogenesis docx
... apoptosis and induces the synthesis of antioxidants [22] Alterations in mitochondrial proteins, on the other hand, are specifically linked to one of the major pathogenetic mechanisms of PD [5] Worthy of ... spots were manually excised and destained (1 · 10 50 lL of K3[Fe(CN)6] 30 mm and Na2S2O3 100 mm; · 10 100 lL of deionized water; · 20 100 lL of NH4HCO3 200 mm; · 20 100 lL of deionized water), dehydrated ... each sample and data were processed using CellQuest software (Becton-Dickinson) Fluorescent emission of propidium iodide and Annexin V-FITC were collected through a 575 and a 530 ⁄ 30 bandpass filter,...
Ngày tải lên: 15/02/2014, 01:20
Tài liệu Venereal Diseases in New Zealand (1922) by Committee Of The Board Of Health pdf
... Zealand "(2.) To inquire into and report any special reasons or causes for the existence of venereal disease in New Zealand "(3.) To advise as to the best means of combating and preventing venereal ... I.—Introductory and Historical Section 1.—Origin and Scope of Inquiry: Witnesses; Sittings, Date and Place of; Appreciation of Services rendered Section 2. Venereal Diseases and their Effects: ... Advantages of; Moral Imbeciles, Danger from; Delayed Marriages; Alcohol; Accidental Infections; Dances; Cinema; Returned Soldiers Part III .—Best Means of Combating and Preventing Venereal Diseases...
Ngày tải lên: 17/02/2014, 14:20
Tài liệu Báo cáo khoa học: Treatment of neutral glycosphingolipid lysosomal storage diseases via inhibition of the ABC drug transporter, MDR1 Cyclosporin A can lower serum and liver globotriaosyl ceramide levels in the Fabry mouse model doc
... levels [9] and the effect of a maintenance dosing of CsA on the recovery of serum Gb3 levels after termination of ERT was determined ERT is an effective means of eliminating serum Gb3, and Gb3 remained ... ng standard Gb3 and was able to detect > ng Gb3 per lL serum sample Gb3 in the serum of wildtype mice was below the background of this assay MDR1 inhibition and GSL storage disease ERT and CsA ... synthesis of most GSLs, including Gb3 (in Fabry disease) and of course, GlcCer (in Gaucher disease) By inhibiting this enzyme, the synthesis of most GSLs (and all gangliosides) is prevented The glucosyl...
Ngày tải lên: 19/02/2014, 07:20
Tài liệu Human Breast Milk: Current Concepts of Immunology and Infectious Diseases pptx
... slowly, reaching 60% of adult levels for IgG1 and IgG3 at year of age, and 60% of adult levels for IgG2 and IgG4 at to years of age.49 IgG2 production begins to develop at about years of age Secretory ... severity of symptoms in formula-fed infants Severity was defined based on scales of number of loose stools and duration, episodes, and duration of emesis, body temperature, and degree of dehydration ... receptors on T- and B-cells The capability of the adaptive immune response to recognize and react against thousands of specific antigens is dependent on T- and B-cell receptor expression and binding...
Ngày tải lên: 22/02/2014, 05:20
Memory performance in healthy elderly without Alzheimer’s disease: effects of time and apolipoprotein-E pptx
... visuospatial and tests of reasoning were the main contributors These included the Rosen Drawing Test [45], matching and recognition components of the Benton Visual Retention Test [4] and the Identities and ... 2000 The role of apolipoprotein E in Alzheimer’s disease, acute brain injury and cerebrovascular disease: evidence of common mechanisms and utility of animal models [In Process Citation] Neurobiol ... decline and dementia J Clin Epidemiol 50(9):1025– 33 [48] Schmand B, Smit JH, Geerlings MI, Lindeboom J 1997 The effects of intelligence and education on the development of dementia A test of the...
Ngày tải lên: 05/03/2014, 21:20
Control of Innate and Adaptive Immune Responses during Infectious Diseases ppt
... neutralization of toxic elements and elimination of replicating organisms and finally healing and remodeling of damaged tissues On one side pathogens evolved mechanisms to evade recognition and killing, ... pathogenesis of many widely prevalent diseases including infectious, cardiovascular and cerebrovascular disease, cancer, obesity and Alzheimer’s disease (Libby 2002; Calder 2006) (Van Dyke and Serhan ... monocytes/macrophages and T cell subsets including Tr1, Treg, and Th1 cells It acts via activation of a transmembrane receptor complex, which is composed of IL-10R1 and IL-10R2, and controls the activities of several...
Ngày tải lên: 05/03/2014, 23:20
Recommendations from the American Thoracic Society, CDC, and the Infectious Diseases Society of America docx
... Assessment of the extent and characteristics of TB in the jurisdiction through collection and analysis of epidemiologic and other data • Development of policies and procedures and of a plan for ... formulate public health policy and make decisions about allocation of resources for disease control and health maintenance and directors and staff members of state, county, and local public health agencies ... approaches to education of medical practitioners, new models for organizing TB services (2), and a clear understanding and acceptance of roles and responsibilities by an expanded group of participants...
Ngày tải lên: 06/03/2014, 04:20
Programmatic update Use of Antiretroviral Drugs for Treating Pregnant Women and Preventing HIV Infection in Infants pptx
... simplify and optimize the use of ARVs and standardize the first-line treatment regimen (8,9); •• reassuring data on the safety of efavirenz in pregnancy (10); and •• the decreasing cost of ARV ... and assess the feasibility, cost-benefit and public health impact of Option B+ WHO advice to countries In light of global and country commitments to elimination of new paediatric infections and ... challenges and problems of expanding coverage and successfully transitioning pregnant women from PMTCT programmes to HIV care and treatment programmes Well-supported referral systems and strong MCH and...
Ngày tải lên: 08/03/2014, 15:20
fraud and responsibilities of auditor in detecting and preventing of fraud
... possibility of innocent mistakes and deliberate misstatements such as fraud and management manipulation (Chandler, Edwards and Anderson, 1993) The role of auditor plays importance in detecting and preventing ... to fraud and the responsibility of auditor in preventing and detecting fraud The objective of chapter is to provide some of various studies and theories around this definition of fraud and responsibilities ... in preventing and detecting of fraud ISA 240 said that the primary responsibility in preventing and uncovering of fraud is both management and governance of entities Hence, both management and...
Ngày tải lên: 13/03/2014, 14:20