— a microdialysis study in patients with severe head injury pdf

... determining factors for fatal outcome in patients with SAP In particular, Luiten and coworkers [8] reported that Gram-negative intestinal colonization (except that with Escherichia coli) carries a ... antibiotic administration, is promising in the case of sterile pancreatic necrosis The same group formulated an algorithm including antibiotic administration as a standard in SAP [12], and repetitively ... investigators lead to the following conclusion; assessment of individual risk and optimal treatment in SAP remain areas of uncertainty A major reason for this uncertainty is misleading statistics,...

Ngày tải lên: 12/08/2014, 20:20

... the treatment of acute spinal cord injury Results of the Third National Acute Spinal Cord Injury Randomized Controlled Trial National Acute Spinal Cord Injury Study JAMA 1997, 277:1597-1604 Alderson ... Lomas G, Cottingham R, Svoboda P, Brayley N, Mazairac G, Laloe V, Munoz-Sanchez A, Arango M, Hartzenberg B, Khamis H, Yutthakasemsunt S, Komolafe E, Olldashi F, Yadav Y, Murillo-Cabezas F, Shakur ... H, Edwards P: Effect of intravenous corticosteroids on death within 14 days in 10008 adults with clinically significant head injury (MRC CRASH trial): randomised placebo-controlled trial Lancet...

Ngày tải lên: 12/08/2014, 22:22

... expiratory pressure (missing in n = 81) ‡ Data available for 167 patients in open and 301 patients in closed ICUs that may play a role in selecting ventilator settings, for example, thoracic ... federal hospital in King County ||Data missing for 12 (4%) of patients in open ICUs and 32 (7%) of patients in closed ICUs ALI = acute lung injury; APACHE = Acute Physiology Assessment and Chronic ... be academic and reside in hospitals caring for large volumes of mechanically ventilated patients, but these differences did not reach statistical significance (Table 1) Day one VT in patients in...

Ngày tải lên: 13/08/2014, 11:23

... expertise; obtaining funding; and drafting, revision, and approval of the manuscript SE was involved in the collection, analysis, and interpretation of the data; provision of study materials and patients; ... patients; and drafting, revision, and approval of the manuscript MM (Mealer) was involved in the collection, analysis, and interpretation of the data; provision of study materials and patients; and approval ... and chest radiographic (CXR) score are initial values calculated from study day Values are expressed as means ± standard deviation or as median (interquartile range) ARDS, acute respiratory distress...

Ngày tải lên: 12/08/2014, 20:21

... levels are expressed as the percentage of the level measured in normal pool plasma Data represent mean ± SD PAP, plasmin-antiplasmin complexes; TAFI-Ag, thrombinactivatable fibrinolysis inhibitor antigen; ... of rhAPC, no other anticoagulant was administered except nadroparin or dalteparin in a prophylactic dose Except for the administration of rhAPC, the treatment of patients in both groups was identical ... downregulated, leading to inadequate activation of protein C and thus to inadequate inhibition of thrombin generation Our findings confirm the results of Dhainaut et al., who demonstrated that treatment...

Ngày tải lên: 12/08/2014, 22:22

... grow at a rate of 1.5% per year [4] As the mortality rate of severe sepsis remains unacceptably high, a group of international critical care and infectious disease physicians, experts in the diagnosis ... executed individually For instance, the highest potential survival rate from cardiac arrest can only be achieved when the cardiac chain of survival, 'the care bundle' in cardiac arrest, occurs as rapidly ... hospital mortality from severe sepsis should focus on increasing compliance with these evidencebased interventions in appropriate patients Additional files The following Additional files are available...

Ngày tải lên: 12/08/2014, 23:20

... Hirashima Y, Nakamura S, Endo S, Kuwayama N, Naruse Y, Takaku A: Elevation of platelet activating factor, inflammatory cytokines, and coagulation factors in the internal jugular vein of patients ... Klauber MR, Marshall LF: Early and late systemic hypotension as a frequent and fundamental source of cerebral ischemia following severe brain injury in the Traumatic Coma Data Bank Acta Neurochir ... MOD-defined cardiovascular failure, SOFA-defined but not MOD-defined cardiovascular failure, MOD-defined but not SOFA-defined cardiovascular failure, and patients without SOFA-defined or MOD-defined...

Ngày tải lên: 13/08/2014, 02:24

... Critical Care Vol 13 No Peng et al started, common inflammatory pathways are invoked Initially, inflammatory reaction takes place within the pancreas, which can lead to systemic inflammatory ... Recently, bacteremia has been identified as an independent factor associated with mortality in patients with acute pancreatitis [20] In fact, bacteremia has also been shown to be an independent factor ... Leppäniemi AK, Kemppainen EA, Puolakkainen PA, Haapiainen RK: Multiple organ dysfunction associated with severe acute pancreatitis Crit Care Med 2002, 30:1274-1279 Bhatia M, Wong FL, Cao Y, Lau HY, Huang...

Ngày tải lên: 13/08/2014, 18:22

... Hospital: Sari Karlsson, Jaana Kallinen, Vesa Parviainen; (6) Seinäjoki Central Hospital: Kari Saarinen, Johanna Kristola, Niina Tuominen; (7) South Karelia Central Hospital: Seppo Hovilehto, Sari Melto, ... Ruokonen, Pertti Arvola, Minna-Liisa Peltola, Anna-Liina Korkala, Jani Heinilä; (18) Kuopio University Hospital: Ilkka Parviainen, Seija Laitinen, Elina Halonen, Mirja Tiainen, Heikki Ahonen; (19) ... decreased in 130 patients and increased in the remaining 25 patients, but the change in PCT concentration was not associated with mortality (P = 0.25) Of the patients with decreasing PCT concentrations,...

Ngày tải lên: 14/08/2014, 07:21

... Hirayama A, Matsuda T, Asakura H, Nakashima M, Aoki N: Efficacy and safety of recombinant human soluble thrombomodulin (ART-123) in disseminated intravascular coagulation: results of a phase ... disseminated intravascular coagulation Statistical analysis Data are expressed as group means ± standard error of the mean, medians with interquartile ranges, or percentages as appropriate Continuous ... whereas improving the acute liver injury and survival rates in experimental endotoxemia Crit Care Med 2009, 37:2181-2186 18 Iba T, Nakarai E, Takayama T, Nakajima K, Sasaoka T, Ohno Y: Combination...

Ngày tải lên: 14/08/2014, 08:21

... Statistics Data were recorded into a database designed with File Maker (FileMaker Inc., Santa Clara, CA, USA) We used Table National Committee on Aeronautics severity of injury or illness index (NACA) ... before arriving at the hospital or were admitted to Stavanger University Hospital We defined severe trauma as a primary diagnosis of traumatic injury and a National Committee on Aeronautics severity ... treating physician, and a variety of anaesthetic drugs are available to facilitate ETI Written guidelines for pre-hospital ETI were available in the Stavanger HEMS during the study period and adhered...

Ngày tải lên: 25/10/2012, 09:56

... FGF-23 in patients with end-stage renal disease on hemodialysis Kidney Int 2004, 65:1943-1946 45 Sato T, Tominaga Y, Ueki T, Goto N, Matsuoka S, Katayama A, Haba T, Uchida K, Nakanishi S, Kazama JJ, ... two patients had AKI after orthotopic liver transplantation, one had cardiorenal syndrome, and one had multifactorial AKI Two patients had Stage I AKI by the AKIN criteria [41], five patients had ... potential study subjects with a baseline creatinine greater than 97 Zhang et al Annals of Intensive Care 2011, 1:21 http://www.annalsofintensivecare.com/content/1/1/21 Page of Table Baseline characteristics...

Ngày tải lên: 21/06/2014, 03:20

... baseline and year later Absolute changes were measured and presented as variation, defined as the final values minus the initial values BMD variation was also represented as relative (%) changes ... Disease Activity Score (DAS)28 [12], and a good clinical response was defined as an improvement of at least 1.2 in DAS28 score at year Bone mineral density evaluation At baseline and year later, ... findings of these usual correlations provide validation of the data at baseline In the study, we were unable to demonstrate an increase in BMD with infliximab, as was recently observed in smaller...

Ngày tải lên: 09/08/2014, 10:20

... clinical trial in patients with RA A proof-of-concept study to explore safety and tolerability, pharmacokinetics and pharmacodynamics was conducted in patients with established RA with ongoing ... time point during the study apy in RA in disease Reductionpatients activity and CRP levels following ACZ885 therapy in RA patients (a) Mean disease activity (Disease Activity Score using 28 joint ... Almost all rheumatologists prefer to administer a TNF blocker rather than anakinra as a first biologic agent to treat RA patients, concordant with a recent consensus statement, and national and...

Ngày tải lên: 09/08/2014, 10:23

... priority within their treatment program It is argued that managing obesity in SMI patients is a challenging task as these patients may have impaired attention, motivation and memory that may impair ... J, Cincotta SL, Baldessarini RJ: Weight loss in overweight patients maintained on atypical antipsychotic agents Int J Obes 2006, 30:1011-1016 Lindenmayer JP, Khan A, Wance D, Maccabee N, Kaushik ... CJ, Bradley AJ, Doshi S, Karagianis J: Changes in weight and metabolic parameters during treatment with antipsychotics and metformin: the data inform as to potential guideline development? A systematic...

Ngày tải lên: 11/08/2014, 16:23

... albumin or saline No pediatric patients received placebo Statistical analysis Data were extracted from validated clinical trial databases All calculations were derived with SAS version 8.2 (SAS Institute, ... and ENHANCE trials APACHE II, acute physiology and chronic health evaluation II; APTT, activated partial thromboplastin time; BL, baseline; DrotAA, drotrecogin alfa (activated); ICH, intracranial ... methods Data collection Data were extracted from four clinical studies investigating DrotAA in adult and pediatric patients with severe sepsis A database of 4,360 patients (4,096 adult, 264 pediatric)...

Ngày tải lên: 12/08/2014, 22:21

... via a rapid qualitative bedside assay The primary a priori population for efficacy analysis was the subgroup of patients with elevated IL-6 levels (n=998) The authors found that mortality was ... Critical Care October 2005 Vol No Rondon and Venkataraman time Nearly sixty randomized controlled clinical trials have been conducted in this area, yet no new agents have been introduced into clinical ... addition of afelimomab to already existing proven therapies, such as drotrecogin alfa (activated) or steroids [6], leads to additional mortality benefits in severe sepsis Competing interests The authors...

Ngày tải lên: 12/08/2014, 22:22

... patients with severe sepsis A total of 73 patients were included in the study APACHE, Acute Physiology and Chronic Health Evaluation; TAC, total antioxidant capacity Statistical analysis All values were ... demographic data, clinical diagnoses, and microbiological data for patients and healthy control individuals are summarized in Table Correlation between serum total antioxidant capacity level and ... sepsis A total of 73 patients were included in the study APACHE, Acute Physiology and Chronic Health Evaluation; UA, uric acid than in control individuals MacKinnon and colleagues [13], in a study...

Ngày tải lên: 12/08/2014, 23:21

... pulmonary disease, heart failure or severe head trauma Their main clinical characteristics are summarized in Table After completing the study and analyzing the data we realized the possible importance ... Cheatham and Safcsak [21] Statistical analysis Data are shown as means ± SD All data were analyzed with SAS software (version 8.2; SAS Institute, Cary, NC, USA) The study design included a baseline ... Blood gas tensions in the arterial and central venous blood were analysed with a blood gas analyzer (IL-1312 Blood Gas Manager; Instrumentation Laboratory, Milan, Italy) Minute metabolic carbon...

Ngày tải lên: 12/08/2014, 23:23

Ngày tải lên: 13/08/2014, 03:20