quality consortia—freedom of action and dependence
Tài liệu BIOCHEMICAL TARGETS OF PLANT BIOACTIVE COMPOUNDS A pharmacological reference guide to sites of action and biological effects doc
... tens of thousands of individual primary scientific papers and reviews describing the isolation, structural characterization, pharmacological effects and biochemical targets of thousands of plant-derived ... chemistry of living things) This biochemical review provides a detailed background for understanding the nature and function of the targets of plant defensive metabolites and proteins The remainder of ... K+-ATPase and Naf, K f -ATPase H Voltage-gated Na+ channel Ligand- and voltage-gated K+ channels + Voltage- and ligand-gated Ca2+channels and ~ a /Ca2+ antiporter CFTR, voltage-gated C channels and...
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Report of the Special Rapporteur on the promotion and protection of the right to freedom of opinion and expression, Frank La Rue* ppt
... the advantages and challenges of new information and communication technologies, including the Internet and mobile technologies, for the exercise of the right to freedom of opinion and expression, ... blocking and filtering, to inadequate guarantees of the right to privacy and protection of personal data, which inhibit the dissemination of opinions and information The Special Rapporteur is of the ... the enjoyment of the right to freedom of opinion and expression, because it leads to self-protective and over-broad private censorship, often without transparency and the due process of the law...
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stenersen - chemical pesticides - mode of action and toxicology (crc, 2004)
... Mode of action and toxicology Dose and effect The law of mass action tells us that the amount of reaction products and the velocity of a chemical reaction increase with the concentrations of the ... the law of mass action, and our knowledge of the nature of the chemical processes in organisms, we can condense biochemical toxicology to three sentences, and about seven types of reactions: ... inhibit synthesis of amino acids 81 5.2.1 The mode of action of glyphosate 81 5.2.2 Degradation of glyphosate 83 5.2.3 Selectivity 84 5.2.4 Mode of action of glufosinate...
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Chemical Pesticides: Mode of Action and Toxicology - Chapter 2 pptx
... Stenersen 2.2.2 Dose and effect The law of mass action tells us that the amount of reaction products and the velocity of a chemical reaction increase with the concentrations of the reactants This ... and resistant flies and a mixture (50:50) of susceptible and resistant flies (a) Doses and responses on linear scales (b) Doses on log scale and responses on probit scale LD50), will be large and ... between dose or concentration of the toxicant and the severity of the symptoms is fundamental in toxicology By using the law of mass action, we get the following equilibrium and mathematical expression:...
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Chemical Pesticides: Mode of Action and Toxicology - Chapter 3 pps
... butachlor, and several others) and a group of fungicides referred to as phenylamides (metalaxyl, ofurace, and oxadixyl) They have similar structure and mode of action: O C CH2R’’ N R R’ R is often ... may be derivatives of urea, s-triazines, anilides, ©2004 by Jorgen Stenersen Table 3.2 Site of Action of Some Mitochondrial Poisons Site of Action Compounds Toxic for Inhibition of acetyl-CoA synthesis ... few of them and give a very brief outline of the photosynthetic process Textbooks of cell biology, biochemistry, and plant physiology (e.g., Alberts et al., 2002; Nelson and Cox, 2000; Taitz and...
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Chemical Pesticides: Mode of Action and Toxicology - Chapter 4 ppt
... in cessation of feeding of Lepidoptera larvae and paralysis of the gut that retards the passage of food and allows the spores to germinate The larvae suffer a general paralysis and die Bt israelensis-treated ... from beach deserts and tundra, and may multiply in cadavers of insects and other animals Insecticidal activity does not correlate with the origin of the isolate, and many of them not seem to ... proteins, and their function and versatility for insect control have yet to be elucidated 4.1 The mechanism of action of δ-endotoxins As mentioned, the δ-endotoxin (Cry protein) that makes up most of...
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Chemical Pesticides: Mode of Action and Toxicology - Chapter 5 docx
... a buffer of pH 7.6 at 37˚C and have the unit min–1 G Schrader (1951, 1963) also synthesized a lot of other derivatives of parathion Parathion-methyl is of similar toxicity and mode of action but ... glutamate and ammonia, and the first common enzyme in the biosynthesis of the branched-chain amino acids 5.2.1 The mode of action of glyphosate The amino acids tryptophan, phenylalanine, and tyrosine ... acetylcholinesterases and the source of the enzyme Most of the data are taken from Aldridge and Reiner (1972) The half-lives and the corresponding k+3 values are dependent on the structure of, and therefore...
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Chemical Pesticides: Mode of Action and Toxicology - Chapter 6 ppsx
... axon and is then transmitted to the receiving cell at the synapse are not extremely complicated, and some knowledge about this mechanism is of importance in understanding the mode of action of ... Stenersen of the synthetic analogues took off in the 1960s when M Elliott and his colleagues at Rothamstead Experimental Station, U.K., began an extensive study of the mechanisms of action and the ... Temp (oC) and DCC: 30 as a function of the temperature Figure 6.2 Toxicity of halocyclopropane analogues of DDT LD50 values for DDT and DCC as functions of the temperature Note that DDT and its...
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Chemical Pesticides: Mode of Action and Toxicology - Chapter 8 pptx
... A and B are constants) They measured the vapor densities of p,p-DDT on sand at 20, 30, and 40˚C and found them to be 2.9, 13.6, and 60.2 ng/l Furthermore, Spencer and Cliath found that DDE and ... an exposure of mg of dieldrin/kg of body weight/day and xenobiotics However, the enormous number of species, the high frequency of mutations per unit time in reproductive cells, and the high ... complicated and involves binding of the substrate to the enzyme, oxidation of Fe+++ to Fe++, change of the valence electrons of Fe++ from low-spin to high-spin orbital, binding of oxygen to iron, and...
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Chemical Pesticides: Mode of Action and Toxicology - Chapter 9 pdf
... to make resistant strains by breeding pairs of insects separately Some of the offspring were used for resistance testing, and the brothers and sisters of insects with low susceptibility were taken ... G.D., and Devonshire, A.L 1998 Pest Sci., 54, 319–320 The cotton bollworm, Helicoverpa armigera, in Australia is of great economic importance and is cross-resistant to parathion-methyl and profenofos, ... N NHCH(CH3)2 conjugate of atrazine and glutathione The data in Table 9.4 are extracted from data of Plaisance and Gronwald (1999) and show the difference in the activity of glutathione transferase...
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Mechanism of action and binding mode revealed by the crystal structures of key enzymes in plants sugar metalbolic pathway
... filtration profile of FRK Crystal of SeMet FRK 3.4 Sample diffraction pattern of SeMet FRK crystal 81 3.5 Crystal structure of HoFRK 85 3.6 Structure based sequence alignment of HoFRK 90 3.7 Stereo ... (magenta) Schematic diagram of the reaction between F6P and UDP-Glc in the binding cleft of SPS A schematic diagram of the reaction involving FRK and Fructose Top a) SDS-GEL image of purified FRK Bottom ... and the actual UDP ligand Superimposition of one docked-ADP ligand and the actual ADP ligand Superimposition of the catalytic regions of the open SPS-F6P complex (cyan) and the closed SPS-S6PUDP...
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lim and tan - 2010 - does auditor tenure improve audit quality moderating effects of industry specialization and fee dependence
... initial years for fear of threats of dismissal and loss of future quasi-rents (Geiger and Raghunandan 2002), this effect should be greater for higher fee dependence as the magnitude of these quasi-rents ... consideration of the auditor’s industry specialization and fee dependence Two interaction patterns are possible, and we discuss each of these in the next two subsections Auditor tenure and industry ... Exchange Commission enforcement actions (Carcello and Nagy 2004b) and are more likely to comply with auditing standards (O’ Keefe, Kin, and Gaver 1994) Effects of fee dependence Economic theory indicates...
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Báo cáo y học: "Does switching from oral extended-release methylphenidate to the methylphenidate transdermal system affect health-related quality-of-life and medication satisfaction for children with attention-deficit/hyperactivity disorder&
... probable predictors of HRQL change and/ or satisfaction will be important in understanding what elements of stimulant treatment contribute most to improvements in HRQL and satisfaction These studies ... evaluated and are the primary focus of this report Page of 12 (page number not for citation purposes) Child and Adolescent Psychiatry and Mental Health 2009, 3:39 The study consisted of experimental ... ongoing AEs Health-related quality of life and medication satisfaction measures As secondary objectives of this study, caregiver-reported HRQL and medication satisfaction were assessed using the...
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Báo cáo y học: "Ultra-low microcurrent in the management of diabetes mellitus, hypertension and chronic wounds: Report of twelve cases and discussion of mechanism of action"
... mellitus High levels of free radicals and the decline of antioxidant defense mechanisms lead to damage of cellular organelles and enzymes, increased lipid peroxidation, and development of insulin resistance ... Popliteal and pedal pulses were absent bilaterally with poor capillary refill The left foot was red and inflamed up to and including the medial malleolus The lateral aspect of the great toe and second ... continued to improve and heal, and her remaining gangrenous toes eventually fell off Her blood pressure at admission was 166/53 with use of Lisinopril, which was dropped and eventually ceased...
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Improvement of Water Quality by Removal of Suspended Solids and High-speed Biological Filtration in Closed Water Body
... pilot plant The height of this plant is 1.5 m and diameter is 0.5 m A 1000-ton of closed water body and a raft of 20×20 m2 were prepared at Tokiwako Lake The maximum water depth of experimental area ... m, and average is 2.3 m Water depth changes around 0.4 m (up and down) by various reasons This plant was floated and fixed at the center of the raft Lake water was - 234 - Journal of Water and ... in each point by standard methods [6] Pore size is 1µm In this paper, SS, transparency and COD at the outlet of plant and the outside of experimental area will be reported and discussed Experimental...
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Tài liệu Freedom of Expression on the Internet - A study of legal provisions and practices related to freedom of expression, the free flow of information and media pluralism on the Internet in OSCE participating States ppt
... the Moscow Meeting of the Conference on the Human Dimension of the CSCE and in breach of Article 19 of the International Covenant on Civil and Political Rights and Article 10 of the European Convention ... to offer the filtering service to their customers and the filtering database and profiles are controlled and maintained by the government Directive 2000/31/EC of the European Parliament and of ... content and even political content In the absence of openness and transparency of the work of hotlines and by creating secrecy surrounding the blocking criteria and keeping the list of blocked...
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Tài liệu GLOBAL SURVEY ON INTERNET PRIVACY AND FREEDOM OF EXPRESSION docx
... freedom of expression and privacy Research on safeguarding the principle of freedom of expression in Internet policy across a range of issues will continue to be part of UNESCO’s normative mandate and ... open and accessible Internet space as part of promoting comprehensive freedom of expression online and offline As demonstrated by UNESCO’s 2011 publication Freedom of Expression: Freedom of Connection, ... policy and practice and awareness raising Finally, Section provides an overview of literature, background material and tools on international and national policy and practice on privacy and freedom...
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Tài liệu Báo cáo khoa học: Antifungal effects and mechanism of action of viscotoxin A3 docx
... monochromator, and Glan-Thompson polarizers using quartz cuvettes with continuous stirring of the suspension, bandwidths of nm for excitation and nm for emission, and excitation and emission wavelengths of ... 79 Analysis of the fungicidal effect of viscotoxin A3 M Giudici et al excitation and emission wavelengths were 360 ⁄ 425 and 362 ⁄ 450 nm for observation of the fluorescence of DPH and TMA-DPH, ... generation of H2O2 in spores [9,15–18] In this work we have gained more information on the cellular targets and the mechanism of action of vis- cotoxins, by examining the interaction of VtA3 with...
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Tài liệu Báo cáo khoa học: Characterization and mode of action of an exopolygalacturonase from the hyperthermophilic bacterium Thermotoga maritima doc
... activity zone of the cytoplasmic fraction (not shown) No activity on PGA was observed when the corresponding medium fraction was concentrated and similarly analysed Mode of action of PelB To examine ... Hiromi K (1970) Interpretation of dependency of rate parameters on the degree of polymerization of substrate in enzyme-catalyzed reactions Evaluation of subsite afnities of exo-enzyme Biochem Biophys ... as the rst and only product on PGA and oligoGalpA On the basis of its mode of action, PelB should be classied as an exopolygalacturonase (EC 3.2.1.67) To date, no crystal structure of an exopolygalacturonase...
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